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Volume 95(15);  July 21, 1998
Commentaries
Telomerase catalysis: A phylogenetically conserved reverse transcriptase
Victoria Lundblad
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8415–8416.
PMCID: PMC33869
Evolution in the light of developmental and cell biology, and vice versa
Mary Jane West-Eberhard
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8417–8419.
PMCID: PMC33870
Perspective
Evolvability
Marc Kirschner and John Gerhart
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8420–8427.
PMCID: PMC33871
The elusive function of metallothioneins
Richard D. Palmiter
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8428–8430.
PMCID: PMC33872
Physical Sciences
Applied Mathematics
Computing geodesic paths on manifolds
R. Kimmel and J. A. Sethian
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8431–8435.
PMCID: PMC21092
Chemistry
Hydration for a series of hydrocarbons
Raymond D. Mountain and D. Thirumalai
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8436–8440.
PMCID: PMC21093
Mathematics
The Weyl character formula, the half-spin representations, and equal rank subgroups
Benedict Gross, Bertram Kostant, Pierre Ramond, and Shlomo Sternberg
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8441–8442.
PMCID: PMC21094
Biological Sciences
Applied Biological Sciences
A model for MRI contrast enhancement using T1 agents
E. T. Ahrens, U. Rothbächer, R. E. Jacobs, and S. E. Fraser
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8443–8448.
PMCID: PMC21095
Biochemistry
Transition state structure of arginine kinase: Implications for catalysis of bimolecular reactions
Genfa Zhou, Thayumanasamy Somasundaram, Eric Blanc, Golapakrishnan Parthasarathy, W. Ross Ellington, and Michael S. Chapman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8449–8454.
PMCID: PMC21096
The solution structure of the DNA-binding domain of Skn-1
Mei-Chu Lo, Sha Ha, István Pelczer, Santona Pal, and Suzanne Walker
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8455–8460.
PMCID: PMC21097
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
Xuesong Liu, Peng Li, Piotr Widlak, Hua Zou, Xu Luo, William T. Garrard, and Xiaodong Wang
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8461–8466.
PMCID: PMC21098
Conversion of a human low-density lipoprotein receptor ligandbinding repeat to a virus receptor: Identification of residues important for ligand specificity
Lijun Rong, Kristin Gendron, and Paul Bates
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8467–8472.
PMCID: PMC21099
Synergy between simulation and experiment in describing the energy landscape of protein folding
Andreas G. Ladurner, Laura S. Itzhaki, Valerie Daggett, and Alan R. Fersht
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8473–8478.
PMCID: PMC21100
Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax
Tracy M. Bryan, Jamie M. Sperger, Karen B. Chapman, and Thomas R. Cech
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8479–8484.
PMCID: PMC21101
The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex
Kathleen Collins and Leena Gandhi
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8485–8490.
PMCID: PMC21102
In vivo and in vitro complementation of the N-terminal domain of enzyme I of the Escherichia coli phosphotransferase system by the cloned C-terminal domain
Alexey Fomenkov, Airat Valiakhmetov, Ludwig Brand, and Saul Roseman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8491–8495.
PMCID: PMC21103
A C-terminal motif found in the β2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins
Randy A. Hall, Lynda S. Ostedgaard, Richard T. Premont, Jeremy T. Blitzer, Nadeem Rahman, Michael J. Welsh, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8496–8501.
PMCID: PMC21104
The allosteric mechanism of the chaperonin GroEL: A dynamic analysis
Jianpeng Ma and Martin Karplus
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8502–8507.
PMCID: PMC21105
3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase
Murat Saparbaev and Jacques Laval
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8508–8513.
PMCID: PMC21106
Activities of adenovirus virus-associated RNAs: Purification and characterization of RNA binding proteins
Huey-Jane Liao, Ryuji Kobayashi, and Michael B. Mathews
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8514–8519.
PMCID: PMC21107
Human thioredoxin reductase from HeLa cells: Selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin
Sergey N. Gorlatov and Thressa C. Stadtman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8520–8525.
PMCID: PMC21108
Concerted formation of macromolecular Suppressor–mutator transposition complexes
Ramesh Raina, Michael Schläppi, Balasulojini Karunanandaa, Adam Elhofy, and Nina Fedoroff
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8526–8531.
PMCID: PMC21109
A cloning method for caspase substrates that uses the yeast two-hybrid system: Cloning of the antiapoptotic gene gelsolin
Shinji Kamada, Hajime Kusano, Hisakazu Fujita, Makoto Ohtsu, Richard Chikara Koya, Noboru Kuzumaki, and Yoshihide Tsujimoto
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8532–8537.
PMCID: PMC21110
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
Yi Wei Jiang, Philippe Veschambre, Hediye Erdjument-Bromage, Paul Tempst, Joan W. Conaway, Ronald C. Conaway, and Roger D. Kornberg
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8538–8543.
PMCID: PMC21111
The exocyclic groups of DNA modulate the affinity and positioning of the histone octamer
Memmo Buttinelli, Andrew Minnock, Gianna Panetta, Michael Waring, and Andrew Travers
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8544–8549.
PMCID: PMC21112
Mechanism of DNA segregation in prokaryotes: Replicon pairing by parC of plasmid R1
Rasmus Bugge Jensen, Rudi Lurz, and Kenn Gerdes
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8550–8555.
PMCID: PMC21113
In search of a mutational hotspot
Zafer Hatahet, Meixia Zhou, Linda J. Reha-Krantz, Scott W. Morrical, and Susan S. Wallace
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8556–8561.
PMCID: PMC21114
Variability in the stability of DNA–peptide nucleic acid (PNA) single-base mismatched duplexes: Real-time hybridization during affinity electrophoresis in PNA-containing gels
Gabor L. Igloi
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8562–8567.
PMCID: PMC21115
Mismatch repair deficiency associated with overexpression of the MSH3 gene
Giancarlo Marra, Ingram Iaccarino, Teresa Lettieri, Giuseppe Roscilli, Paola Delmastro, and Josef Jiricny
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8568–8573.
PMCID: PMC21116
Control of retinoblastoma protein-independent hematopoietic cell cycle by the pRB-related p130
Yutaka Hoshikawa, Akio Mori, Keiko Amimoto, Koji Iwabe, and Masanori Hatakeyama
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8574–8579.
PMCID: PMC21117
Biophysics
“Hidden” sequence periodicities and protein architecture
S. Rackovsky
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8580–8584.
PMCID: PMC21118
Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca2+ and K+ channels
Yingying Li-Smerin and Kenton J. Swartz
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8585–8589.
PMCID: PMC21119
The proton collecting function of the inner surface of cytochrome c oxidase from Rhodobacter sphaeroides
Yael Marantz, Esther Nachliel, Anna Aagaard, Peter Brzezinski, and Menachem Gutman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8590–8595.
PMCID: PMC21120
Identification of viral mutants by mass spectrometry
J. Kathleen Lewis, Mohammed Bendahmane, Thomas J. Smith, Roger N. Beachy, and Gary Siuzdak
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8596–8601.
PMCID: PMC21121
Kinetics of conformational fluctuations in DNA hairpin-loops
Grégoire Bonnet, Oleg Krichevsky, and Albert Libchaber
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8602–8606.
PMCID: PMC21122
Cell Biology
ADP ribosylation factor regulates spectrin binding to the Golgi complex
Anna Godi, Ivana Santone, Paolo Pertile, Prasad Devarajan, Paul R. Stabach, Jon S. Morrow, Giuseppe Di Tullio, Roman Polishchuk, Tamara C. Petrucci, Alberto Luini, and Maria Antonietta De Matteis
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8607–8612.
PMCID: PMC21123
Localization of ADP-ribosylation factor domain protein 1 (ARD1) in lysosomes and Golgi apparatus
Nicolas Vitale, Koji Horiba, Victor J. Ferrans, Joel Moss, and Martha Vaughan
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8613–8618.
PMCID: PMC21124
A yeast glutamine tRNA signals nitrogen status for regulation of dimorphic growth and sporulation
L. E. Murray, N. Rowley, I. W. Dawes, G. C. Johnston, and R. A. Singer
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8619–8624.
PMCID: PMC21125
A family of fatty acid transporters conserved from mycobacterium to man
David Hirsch, Andreas Stahl, and Harvey F. Lodish
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8625–8629.
PMCID: PMC21126
Disruption of a PEX1–PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum disease
Brian V. Geisbrecht, Cynthia S. Collins, Bernadette E. Reuber, and Stephen J. Gould
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8630–8635.
PMCID: PMC21127
Localization of myosin-V in the centrosome
Enilza M. Espreafico, Donald E. Coling, Vasiliki Tsakraklides, Karin Krogh, Joseph S. Wolenski, Gilda Kalinec, and Bechara Kachar
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8636–8641.
PMCID: PMC21128
Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation
Paul de Figueiredo, Daniel Drecktrah, John A. Katzenellenbogen, Marian Strang, and William J. Brown
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8642–8647.
PMCID: PMC21129
Telomere length regulation in mice is linked to a novel chromosome locus
Lingxiang Zhu, Karen S. Hathcock, Prakash Hande, Peter M. Lansdorp, Michael F. Seldin, and Richard J. Hodes
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8648–8653.
PMCID: PMC21130
Developmental Biology
Targeted oncogenesis of hormone-negative pancreatic islet progenitor cells
Thomas L. Jetton, J. Michael Moates, Jill Lindner, Christopher V. E. Wright, and Mark A. Magnuson
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8654–8659.
PMCID: PMC21131
Evolution
Resonating circadian clocks enhance fitness in cyanobacteria
Yan Ouyang, Carol R. Andersson, Takao Kondo, Susan S. Golden, and Carl Hirschie Johnson
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8660–8664.
PMCID: PMC21132
Productivity, individual-level and colony-level flexibility, and organization of work as consequences of colony size
István Karsai and John W. Wenzel
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8665–8669.
PMCID: PMC21133
Antarctic fish hemoglobins: Evidence for adaptive evolution at subzero temperature
Luca Bargelloni, Stefania Marcato, and Tomaso Patarnello
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8670–8675.
PMCID: PMC21134
The evolution of interspecific mutualisms
Michael Doebeli and Nancy Knowlton
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8676–8680.
PMCID: PMC21135
Testing migration patterns and estimating founding population size in Polynesia by using human mtDNA sequences
Rosalind P. Murray-McIntosh, Brian J. Scrimshaw, Peter J. Hatfield, and David Penny
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9047–9052.
PMCID: PMC21200
Genetics
A member of a family of sulfate-activating enzymes causes murine brachymorphism
Kiyoto Kurima, Matthew L. Warman, Srinivasan Krishnan, Miriam Domowicz, Richard C. Krueger, Jr., Andrea Deyrup, and Nancy B. Schwartz
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8681–8685.
PMCID: PMC21136
Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes
Martin Raabe, Laura M. Flynn, Constance H. Zlot, Jinny S. Wong, Murielle M. Véniant, Robert L. Hamilton, and Stephen G. Young
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8686–8691.
PMCID: PMC21137
Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency
Bettina Wilm, Edgar Dahl, Heiko Peters, Rudi Balling, and Kenji Imai
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8692–8697.
PMCID: PMC21138
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
Martina L. Veigl, Lakshmi Kasturi, Joseph Olechnowicz, AiHong Ma, James D. Lutterbaugh, Sumudra Periyasamy, Guo-Min Li, James Drummond, Paul L. Modrich, W. David Sedwick, and Sanford D. Markowitz
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8698–8702.
PMCID: PMC21139
Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma
Colin Collins, Johanna M. Rommens, David Kowbel, Tony Godfrey, Minna Tanner, Soo-in Hwang, Daniel Polikoff, Genevieve Nonet, Joanne Cochran, Ken Myambo, Karen E. Jay, Jeff Froula, Thomas Cloutier, Wen-Lin Kuo, Paul Yaswen, Shanaz Dairkee, Jennifer Giovanola, Gordon B. Hutchinson, Jorma Isola, Olli-P Kallioniemi, Mike Palazzolo, Chris Martin, Cheryl Ericsson, Dan Pinkel, Donna Albertson, Wu-Bo Li, and Joe W. Gray
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8703–8708.
PMCID: PMC21140
Chromosomal basis of X chromosome inactivation: Identification of a multigene domain in Xp11.21-p11.22 that escapes X inactivation
Andrew P. Miller and Huntington F. Willard
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8709–8714.
PMCID: PMC21141
Variable and tissue-specific hormone resistance in heterotrimeric Gs protein α-subunit (Gsα) knockout mice is due to tissue-specific imprinting of the Gsα gene
Shuhua Yu, Dawen Yu, Eric Lee, Michael Eckhaus, Randy Lee, Zakia Corria, Domenico Accili, Heiner Westphal, and Lee S. Weinstein
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8715–8720.
PMCID: PMC21142
The Upf3 protein is a component of the surveillance complex that monitors both translation and mRNA turnover and affects viral propagation
Maria J. Ruiz-Echevarría, Jason M. Yasenchak, Xia Han, Jonathan D. Dinman, and Stuart W. Peltz
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8721–8726.
PMCID: PMC21143
Evidence for gene silencing by endogenous DNA methylation
Robin Holliday and Thu Ho
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8727–8732.
PMCID: PMC21144
Bloom’s and Werner’s syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases
Kazutsune Yamagata, Jun-ichi Kato, Akira Shimamoto, Makoto Goto, Yasuhiro Furuichi, and Hideo Ikeda
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8733–8738.
PMCID: PMC21145
Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability
Agnes Baross-Francis, Susan E. Andrew, Janice E. Penney, and Frank R. Jirik
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8739–8743.
PMCID: PMC21146
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans
Yuri Pekarsky, Manuela Campiglio, Zurab Siprashvili, Teresa Druck, Yurii Sedkov, Sergei Tillib, Alexandra Draganescu, Peter Wermuth, Joel H. Rothman, Kay Huebner, Arthur M. Buchberg, Alexander Mazo, Charles Brenner, and Carlo M. Croce
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8744–8749.
PMCID: PMC21147
Male-specific transcription initiation of the C4-Slp gene in mouse liver follows activation of STAT5
N. Varin-Blank, E. Dondi, M. Tosi, C. Hernandez, L. Boucontet, H. Gotoh, T. Shiroishi, K. Moriwaki, and T. Meo
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8750–8755.
PMCID: PMC21148
Mitogen-activated protein kinases enhance long-range activation by the β-globin locus control region
Wayne K. Versaw, Volker Blank, Nancy M. Andrews, and Emery H. Bresnick
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8756–8760.
PMCID: PMC21149
unc-1: A stomatin homologue controls sensitivity to volatile anesthetics in Caenorhabditis elegans
S. Rajaram, M. M. Sedensky, and P. G. Morgan
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8761–8766.
PMCID: PMC21150
α-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration
David K. Jin, Jean Vacher, and Miriam H. Feuerman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8767–8772.
PMCID: PMC21151
Signaling pathways in Ras-mediated tumorigenicity and metastasis
Craig P. Webb, Linda Van Aelst, Michael H. Wigler, and George F. Vande Woude
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8773–8778.
PMCID: PMC21152
Immunology
FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells
Junke Liu, Hyun Kang, Monika Raab, Antonio J. da Silva, Stine-Kathrein Kraeft, and Christopher E. Rudd
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8779–8784.
PMCID: PMC21153
Activation of preexisting T cell clones by targeted interleukin 2 therapy
Per thor Straten, Per Guldberg, Tina Seremet, Ralph A. Reisfeld, Jesper Zeuthen, and Jürgen C. Becker
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8785–8790.
PMCID: PMC21154
Both DNA strands of antibody genes are hypermutation targets
Cesar Milstein, Michael S. Neuberger, and Rodger Staden
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8791–8794.
PMCID: PMC21155
Medical Sciences
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
Corey K. Goldman, Richard L. Kendall, Gustavo Cabrera, Liliana Soroceanu, Yuji Heike, G. Yancey Gillespie, Gene P. Siegal, Xianzhi Mao, Andrew J. Bett, William R. Huckle, Kenneth A. Thomas, and David T. Curiel
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8795–8800.
PMCID: PMC21156
Myocyte proliferation in end-stage cardiac failure in humans
Jan Kajstura, Annarosa Leri, Nicoletta Finato, Carla Di Loreto, Carlo A. Beltrami, and Piero Anversa
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8801–8805.
PMCID: PMC21157
Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
Elena Elstner, Carsten Müller, Kozo Koshizuka, Elizabeth A. Williamson, Dorothy Park, Hiroya Asou, Peter Shintaku, Jonathan W. Said, David Heber, and H. Phillip Koeffler
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8806–8811.
PMCID: PMC21158
Prion protein expression in different species: Analysis with a panel of new mAbs
Gianluigi Zanusso, Dacai Liu, Sergio Ferrari, Ivan Hegyi, Xinghua Yin, Adriano Aguzzi, Simone Hornemann, Susanne Liemann, Rudi Glockshuber, Jean C. Manson, Paul Brown, Robert B. Petersen, Pierluigi Gambetti, and Man-Sun Sy
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8812–8816.
PMCID: PMC21159
A second major native von Hippel–Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor
Alan Schoenfeld, Eliot J. Davidowitz, and Robert D. Burk
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8817–8822.
PMCID: PMC21160
Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice
Stefan Ambs, Mofolusara O. Ogunfusika, William G. Merriam, William P. Bennett, Timothy R. Billiar, and Curtis C. Harris
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8823–8828.
PMCID: PMC21161
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2
Pengnian Lin, Jake A. Buxton, Ann Acheson, Czeslaw Radziejewski, Peter C. Maisonpierre, George D. Yancopoulos, Keith M. Channon, Laura P. Hale, Mark W. Dewhirst, Samuel E. George, and Kevin G. Peters
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8829–8834.
PMCID: PMC21162
hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer
A. Varrault, E. Ciani, F. Apiou, B. Bilanges, A. Hoffmann, C. Pantaloni, J. Bockaert, D. Spengler, and L. Journot
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8835–8840.
PMCID: PMC21163
Mast cells mediate acute inflammatory responses to implanted biomaterials
Liping Tang, Timothy A. Jennings, and John W. Eaton
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8841–8846.
PMCID: PMC21164
Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas
Alix de La Coste, Béatrice Romagnolo, Pierre Billuart, Claire-Angélique Renard, Marie-Annick Buendia, Olivier Soubrane, Monique Fabre, Jamel Chelly, Cherif Beldjord, Axel Kahn, and Christine Perret
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8847–8851.
PMCID: PMC21165
The Epstein–Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression
Vivian Ruvolo, Eryu Wang, Sarah Boyle, and Sankar Swaminathan
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8852–8857.
PMCID: PMC21166
Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53
Angela M. Pierce, Irma B. Gimenez-Conti, Robin Schneider-Broussard, Luis A. Martinez, Claudio J. Conti, and David G. Johnson
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8858–8863.
PMCID: PMC21167
Growth hormone-releasing hormone antagonist MZ-5-156 inhibits growth of DU-145 human androgen-independent prostate carcinoma in nude mice and suppresses the levels and mRNA expression of insulin-like growth factor II in tumors
Najib Lamharzi, Andrew V. Schally, Miklós Koppán, and Kate Groot
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8864–8868.
PMCID: PMC21168
Early establishment of a pool of latently infected, resting CD4+ T cells during primary HIV-1 infection
Tae-Wook Chun, Delphine Engel, M. Michelle Berrey, Theresa Shea, Lawrence Corey, and Anthony S. Fauci
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8869–8873.
PMCID: PMC21169
Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA
Mark R. Player, Dale L. Barnard, and Paul F. Torrence
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8874–8879.
PMCID: PMC21170
Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
Matthias Endres, Ulrich Laufs, Zhihong Huang, Tadashi Nakamura, Paul Huang, Michael A. Moskowitz, and James K. Liao
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8880–8885.
PMCID: PMC21171
Dual effect of interleukin 4 on HIV-1 expression: Implications for viral phenotypic switch and disease progression
Antonio Valentin, Wenhong Lu, Margherita Rosati, Ralf Schneider, Jan Albert, Anders Karlsson, and George N. Pavlakis
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8886–8891.
PMCID: PMC21172
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
Russell T. Matthews, Lichuan Yang, Susan Browne, Myong Baik, and M. Flint Beal
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8892–8897.
PMCID: PMC21173
Role of peroxisome proliferator-activated receptor α in disease of pancreatic β cells
Yan-Ting Zhou, Michio Shimabukuro, May-Yun Wang, Young Lee, Moritake Higa, Joseph L. Milburn, Christopher B. Newgard, and Roger H. Unger
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8898–8903.
PMCID: PMC21174
Leukoregulin induction of protein expression in human orbital fibroblasts: Evidence for anatomical site-restricted cytokine–target cell interactions
Donald A. Young, Charles H. Evans, and Terry J. Smith
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8904–8909.
PMCID: PMC21175
A phage display approach for rapid antibody humanization: Designed combinatorial V gene libraries
Christoph Rader, David A. Cheresh, and Carlos F. Barbas, III
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8910–8915.
PMCID: PMC21176
Microbiology
A bacterial cytokine
Galina V. Mukamolova, Arseny S. Kaprelyants, Danielle I. Young, Michael Young, and Douglas B. Kell
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8916–8921.
PMCID: PMC21177
Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin
Evgeni V. Sokurenko, Veronika Chesnokova, Daniel E. Dykhuizen, Itzhak Ofek, Xue-Ru Wu, Karen A. Krogfelt, Carsten Struve, Mark A. Schembri, and David L. Hasty
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8922–8926.
PMCID: PMC21178
Systematic identification of essential genes by in vitro mariner mutagenesis
Brian J. Akerley, Eric J. Rubin, Andrew Camilli, David J. Lampe, Hugh M. Robertson, and John J. Mekalanos
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8927–8932.
PMCID: PMC21179
Neurobiology
Characterization and solubilization of bitter-responsive receptors that couple to gustducin
Ding Ming, Luis Ruiz-Avila, and Robert F. Margolskee
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8933–8938.
PMCID: PMC21180
Functional connectivity of the angular gyrus in normal reading and dyslexia
B. Horwitz, J. M. Rumsey, and B. C. Donohue
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8939–8944.
PMCID: PMC21181
Spatiotemporal imaging of human brain activity using functional MRI constrained magnetoencephalography data: Monte Carlo simulations
Arthur K. Liu, John W. Belliveau, and Anders M. Dale
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8945–8950.
PMCID: PMC21182
Social inhibition of song imitation among sibling male zebra finches
Ofer Tchernichovski and Fernando Nottebohm
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8951–8956.
PMCID: PMC21183
The superior colliculus–pretectum mediates the direct effects of light on sleep
Ann M. Miller, William H. Obermeyer, Mary Behan, and Ruth M. Benca
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8957–8962.
PMCID: PMC21184
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
S. D. Dib-Hajj, L. Tyrrell, J. A. Black, and S. G. Waxman
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8963–8968.
PMCID: PMC21185
Direct effects of metabotropic glutamate receptor compounds on native and recombinant N-methyl-d-aspartate receptors
Anis Contractor, Robert W. Gereau, IV, Tim Green, and Stephen F. Heinemann
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8969–8974.
PMCID: PMC21186
Geometric and viscous components of the tortuosity of the extracellular space in the brain
Dmitri A. Rusakov and Dimitri M. Kullmann
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8975–8980.
PMCID: PMC21187
Visual representations during saccadic eye movements
Tirin Moore, Andreas S. Tolias, and Peter H. Schiller
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8981–8984.
PMCID: PMC21188
Pharmacology
Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic, acid-stimulated mitogenic activity in L cells
Andreas Herrlich, Henrik Daub, Axel Knebel, Peter Herrlich, Axel Ullrich, Günter Schultz, and Thomas Gudermann
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8985–8990.
PMCID: PMC21189
Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase
S. H. Soderling, S. J. Bayuga, and J. A. Beavo
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8991–8996.
PMCID: PMC21190
Physiology
S-Sulfohemoglobin and disulfide exchange: The mechanisms of sulfide binding by Riftia pachyptila hemoglobins
Franck Zal, Emmanuelle Leize, François H. Lallier, André Toulmond, Alain Van Dorsselaer, and James J. Childress
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 8997–9002.
PMCID: PMC21191
Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells
Stepan Gambaryan, Charlotte Wagner, Albert Smolenski, Ulrich Walter, Wolfgang Poller, Winfried Haase, Armin Kurtz, and Suzanne M. Lohmann
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9003–9008.
PMCID: PMC21192
Plant Biology
Ferredoxin-1 mRNA is destabilized by changes in photosynthetic electron transport
Marie E. Petracek, Lynn F. Dickey, Tuyen T. Nguyen, Christiane Gatz, Dolores A. Sowinski, George C. Allen, and William F. Thompson
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9009–9013.
PMCID: PMC21193
Successful search for a resistance gene in tomato targeted against a virulence factor of a fungal pathogen
Richard Laugé, Matthieu H. A. J. Joosten, Jair P. W. Haanstra, Paul H. Goodwin, Pim Lindhout, and Pierre J. G. M. De Wit
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9014–9018.
PMCID: PMC21194
Cloning of the Arabidopsis ent-kaurene oxidase gene GA3
Chris A. Helliwell, Candice C. Sheldon, Mark R. Olive, Amanda R. Walker, Jan A. D. Zeevaart, W. James Peacock, and Elizabeth S. Dennis
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9019–9024.
PMCID: PMC21195
His-65 in the proton–sucrose symporter is an essential amino acid whose modification with site-directed mutagenesis increases transport activity
Jade M.-Y. Lu and Daniel R. Bush
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9025–9030.
PMCID: PMC21196
Population Biology
Chytridiomycosis causes amphibian mortality associated with population declines in the rain forests of Australia and Central America
Lee Berger, Rick Speare, Peter Daszak, D. Earl Green, Andrew A. Cunningham, C. Louise Goggin, Ron Slocombe, Mark A. Ragan, Alex D. Hyatt, Keith R. McDonald, Harry B. Hines, Karen R. Lips, Gerry Marantelli, and Helen Parkes
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9031–9036.
PMCID: PMC21197
Mortality invariants and their genetic implications
Mark Yacov Azbel’
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9037–9041.
PMCID: PMC21198
Psychology
Interhemispheric disconnection syndrome in Alzheimer’s disease
Yamina Lakmache, Maryse Lassonde, Serge Gauthier, Jean-Yves Frigon, and Franco Lepore
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9042–9046.
PMCID: PMC21199
Social Sciences
Anthropology
Testing migration patterns and estimating founding population size in Polynesia by using human mtDNA sequences
Rosalind P. Murray-McIntosh, Brian J. Scrimshaw, Peter J. Hatfield, and David Penny
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9047–9052.
PMCID: PMC21200
Clines of nuclear DNA markers suggest a largely Neolithic ancestry of the European gene pool
Lounès Chikhi, Giovanni Destro-Bisol, Giorgio Bertorelle, Vincenzo Pascali, and Guido Barbujani
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9053–9058.
PMCID: PMC21201
Corrections
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9059.
PMCID: PMC56045
Corrects: Lothar Trieschmann, et al. The chromatin unfolding domain of chromosomal protein HMG-14 targets the N-terminal tail of histone H3 in nucleosomes. Proc Natl Acad Sci U S A. 1998 May 12; 95(10): 5468–5473.
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9059.
PMCID: PMC56046
Corrects: John T. Sullivan, et al. Evolution of rhizobia by acquisition of a 500-kb symbiosis island that integrates into a phe-tRNA gene. Proc Natl Acad Sci U S A. 1998 April 28; 95(9): 5145–5149.
Proc Natl Acad Sci U S A. 1998 July 21; 95(15): 9059.
PMCID: PMC56047
Corrects: Karen L. Clark, et al. Association of the Arabidopsis CTR1 Raf-like kinase with the ETR1 and ERS ethylene receptors. Proc Natl Acad Sci U S A. 1998 April 28; 95(9): 5401–5406.
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