| | This journal provides immediate access to some articles. From the Academy Introduction to German-American Frontiers of Science PMCID: PMC33621 Ultrafast detection and control of molecular dynamics Philip Anfinrud, Regina de Vivie-Riedle, and Volker Engel PMCID: PMC33622 Smart materials and structures Wenwu Cao, Harley H. Cudney, and Rainer Waser PMCID: PMC33623 The mathematics of microstructure and the design of
new materials K. Bhattacharya, G. Friesecke, and R. D. James PMCID: PMC33624 The past and the future fate of the universe and the formation of
structure in it Hans-Walter Rix PMCID: PMC33625 Emerging fluorescence sensing technologies: From photophysical
principles to cellular applications A. Prasanna de Silva, Jens Eilers, and Gregor Zlokarnik PMCID: PMC33626 Commentaries On the mechanism of silencing in Escherichia coli Jasper Rine PMCID: PMC33615 How to induce involuntary suicide: The need for
dipeptidyl peptidase I Eckhard R. Podack PMCID: PMC33616 A paradigm for finding genes for a complex human trait: Polycystic
ovary syndrome and follistatin Kunle Odunsi and Kenneth K. Kidd PMCID: PMC33617 Here’s the hook: Similar substrate binding sites in the chaperone
domains of Clp and Lon Sue Wickner and Michael R. Maurizi PMCID: PMC33618 Gene therapy in plants Barbara Hohn and Holger Puchta PMCID: PMC33619 Perspective Tat as one key to HIV-induced immune pathogenesis and Pat toxoid as an
important component of a vaccine Robert C. Gallo PMCID: PMC33620 Physical Sciences Chemistry Resolution of concerted versus sequential mechanisms in photo-induced double-proton transfer reaction in 7-azaindole H-bonded dimer Javier Catalán, Juan Carlos del Valle, and Michael Kasha PMCID: PMC17518 Guest exchange in an encapsulation complex: A supramolecular substitution reaction Javier Santamaría, Tomás Martín, Göran Hilmersson, Stephen L. Craig, and Julius Rebek, Jr. PMCID: PMC17519 Potent selective nonpeptidic inhibitors of human lung tryptase Laurence E. Burgess, Bradley J. Newhouse, Prabha Ibrahim, James Rizzi, Mohammed A. Kashem, Ann Hartman, Barbara J. Brandhuber, Clifford D. Wright, David S. Thomson, Guy P. A. Vigers, and Kevin Koch PMCID: PMC17520 Long-distance charge transport in duplex DNA: The phonon-assisted polaron-like hopping mechanism Paul T. Henderson, Denise Jones, Gregory Hampikian, Yongzhi Kan, and Gary B. Schuster PMCID: PMC17521 Mathematics Dynamics of Helicobacter pylori colonization in relation to the host response Martin J. Blaser and Denise Kirschner PMCID: PMC17522 Physics INAUGURAL ARTICLE by a Recently Elected Academy Member: A “midinfrared” scenario for
cuprate superconductivity A. J. Leggett PMCID: PMC31091 Biological Sciences Agricultural Sciences Genetic mapping of resistance to Bacillus thuringiensis toxins in diamondback moth using biphasic linkage analysis David G. Heckel, Linda J. Gahan, Yong-Biao Liu, and Bruce E. Tabashnik PMCID: PMC17523 Biochemistry Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1 Sirano Dhe-Paganon, Elizabeth A. Ottinger, Robert T. Nolte, Michael J. Eck, and Steven E. Shoelson PMCID: PMC17524 A structural snapshot of an intermediate on the
streptavidin–biotin dissociation pathway Stefanie Freitag, Vano Chu, Julie E. Penzotti, Lisa A. Klumb, Richard To, David Hyre, Isolde Le Trong, Terry P. Lybrand, Ronald E. Stenkamp, and Patrick S. Stayton PMCID: PMC17525 Interactions of Escherichia coli σ70 within the transcription elongation complex Shirley S. Daube and Peter H. von Hippel PMCID: PMC17526 Crystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motif Xin Chen, Donald L. Court, and Xinhua Ji PMCID: PMC17527 A novel function for transglutaminase 1: Attachment of long-chain ω-hydroxyceramides to involucrin by ester bond formation Zoltán Nemes, Lyuben N. Marekov, Lázló Fésüs, and Peter M. Steinert PMCID: PMC17528 Crystallographic analysis of CD40 recognition and signaling by human TRAF2 Sarah M. McWhirter, Steven S. Pullen, James M. Holton, James J. Crute, Marilyn R. Kehry, and Tom Alber PMCID: PMC17529 A model for the mechanism of strand passage by DNA gyrase Sotirios C. Kampranis, Andrew D. Bates, and Anthony Maxwell PMCID: PMC17530 Three-dimensional structure of low density lipoproteins by electron cryomicroscopy Elena V. Orlova, Michael B. Sherman, Wah Chiu, Hiro Mowri, Louis C. Smith, and Antonio M. Gotto, Jr. PMCID: PMC17531 Protein preservation and DNA retrieval from ancient tissues Hendrik N. Poinar and B. Artur Stankiewicz PMCID: PMC17532 A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation Jeffrey R. Allen, Daniel D. Clark, Jonathan G. Krum, and Scott A. Ensign PMCID: PMC17533 Hot-spot mutants of p53 core domain evince characteristic local structural changes Kam-Bo Wong, Brian S. DeDecker, Stefan M. V. Freund, Mark R. Proctor, Mark Bycroft, and Alan R. Fersht PMCID: PMC17534 Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase Grant W. Brown and Thomas J. Kelly PMCID: PMC17535 Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes Jennifer T. Thomas, Walter G. Hubert, Margaret N. Ruesch, and Laimonis A. Laimins PMCID: PMC17536 The kinetoplast structure-specific endonuclease I is related to the 5′ exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase β during replication Michele L. Engel and Dan S. Ray PMCID: PMC17537 Gene silencing via protein-mediated subcellular localization of DNA Sook-Kyung Kim and James C. Wang PMCID: PMC17555 Biophysics Characterization of lipid bilayer phases by confocal microscopy and fluorescence correlation spectroscopy Jonas Korlach, Petra Schwille, Watt W. Webb, and Gerald W. Feigenson PMCID: PMC17538 Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain Kyoung Joon Oh, Lisa Senzel, R. John Collier, and Alan Finkelstein PMCID: PMC17539 Mapping the sensitivity of T cells with an optical trap: Polarity and minimal number of receptors for Ca2+ signaling Xunbin Wei, Bruce J. Tromberg, and Michael D. Cahalan PMCID: PMC17540 A systematic study of low-resolution recognition in protein–protein complexes Ilya A. Vakser, Omar G. Matar, and Chan F. Lam PMCID: PMC17541 Cell Biology Development of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermis Xiao-Jing Wang, Kristin M. Liefer, Sophia Tsai, Bert W. O’Malley, and Dennis R. Roop PMCID: PMC17542 The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control Laura Sard, Paola Accornero, Silvana Tornielli, Domenico Delia, Giuseppe Bunone, Manuela Campiglio, Mario P. Colombo, Marcella Gramegna, Carlo M. Croce, Marco A. Pierotti, and Gabriella Sozzi PMCID: PMC17543 Retention of the Bub3 checkpoint protein on lagging chromosomes Maria J. Martinez-Exposito, Kenneth B. Kaplan, Jay Copeland, and Peter K. Sorger PMCID: PMC17544 TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions Josh Syken, Tali De-Medina, and Karl Münger PMCID: PMC17545 Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression Joseph W. Brewer, Linda M. Hendershot, Charles J. Sherr, and J. Alan Diehl PMCID: PMC17546 Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins Lixin Zhang, Jing Chen, and Haian Fu PMCID: PMC17547 The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products Craig M. Story, Margo H. Furman, and Hidde L. Ploegh PMCID: PMC17548 Hsl7p, a negative regulator of Ste20p protein kinase in the Saccharomyces cerevisiae filamentous growth-signaling pathway Atsushi Fujita, Akio Tonouchi, Takatoshi Hiroko, Fumika Inose, Takeyuki Nagashima, Rika Satoh, and Shigeko Tanaka PMCID: PMC17549 Developmental Biology Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals Cheng-Kui Qu, Wen-Mei Yu, Biagio Azzarelli, and Gen-Sheng Feng PMCID: PMC17550 Ecology Natural 13C abundance reveals trophic status of fungi and host-origin of carbon in mycorrhizal fungi in mixed forests Peter Högberg, Agneta H. Plamboeck, Andrew F. S. Taylor, and Petra M. A. Fransson PMCID: PMC17551 Evolution Divergent evolution of membrane protein topology: The Escherichia coli RnfA and RnfE homologues Annika Sääf, Marie Johansson, Erik Wallin, and Gunnar von Heijne PMCID: PMC17552 Transcription in Archaea Nikos C. Kyrpides and Christos A. Ouzounis PMCID: PMC17553 Genetics The magical touch: Genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin Valeri Vasioukhin, Linda Degenstein, Bart Wise, and Elaine Fuchs PMCID: PMC17554 Gene silencing via protein-mediated subcellular localization of DNA Sook-Kyung Kim and James C. Wang PMCID: PMC17555 Mucolipidosis IV consists of one complementation group Ehud Goldin, Adele Cooney, Christine R. Kaneski, Roscoe O. Brady, and Raphael Schiffmann PMCID: PMC17556 “Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections C. Ronald Geyer, Alejandro Colman-Lerner, and Roger Brent PMCID: PMC17557 Thirty-seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with follistatin Margrit Urbanek, Richard S. Legro, Deborah A. Driscoll, Ricardo Azziz, David A. Ehrmann, Robert J. Norman, Jerome F. Strauss, III, Richard S. Spielman, and Andrea Dunaif PMCID: PMC17558 An agouti mutation lacking the basic domain induces yellow pigmentation but not obesity in transgenic mice R. J. Miltenberger, R. L. Mynatt, B. D. Bruce, W. O. Wilkison, R. P. Woychik, and E. J. Michaud PMCID: PMC17559 Immunology Stromal cell-derived factor 1 (SDF-1) and antenatal human B cell lymphopoiesis: Expression of SDF-1 by mesothelial cells and biliary ductal plate epithelial cells Aurore Coulomb-L’Herminé, Ali Amara, Claudine Schiff, Ingrid Durand-Gasselin, Arnaud Foussat, Thierry Delaunay, Gérard Chaouat, Frédérique Capron, Nathalie Ledee, Pierre Galanaud, Fernando Arenzana-Seisdedos, and Dominique Emilie PMCID: PMC17560 Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12 Holger N. Lode, Rong Xiang, Steven R. Duncan, Argyrios N. Theofilopoulos, Stephen D. Gillies, and Ralph A. Reisfeld PMCID: PMC17561 In vivo proliferation of naïve and memory influenza-specific CD8+ T cells Kirsten J. Flynn, Janice M. Riberdy, Jan P. Christensen, John D. Altman, and Peter C. Doherty PMCID: PMC17562 Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+ T cell responses Cynthia A. Chambers, Michael S. Kuhns, and James P. Allison PMCID: PMC17563 Induction of hyporesponsiveness to intact foreign protein via retroviral-mediated gene expression: The IgG scaffold is important for induction and maintenance of immune hyporesponsiveness Yubin Kang, Marco Melo, Edward Deng, Roland Tisch, Moustapha El-Amine, and David W. Scott PMCID: PMC17564 One Lyn molecule is sufficient to initiate phosphorylation of aggregated high-affinity IgE receptors Carla Wofsy, Becky M. Vonakis, Henry Metzger, and Byron Goldstein PMCID: PMC17565 The lack of consensus for I-Ag7-peptide binding motifs: Is there a requirement for anchor amino acid side chains? Eugenio Carrasco-Marin, Osami Kanagawa, and Emil R. Unanue PMCID: PMC17566 Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo Christine T. N. Pham and Timothy J. Ley PMCID: PMC17567 CD4+ T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-γ Dominik Mumberg, Paul A. Monach, Sherry Wanderling, Mary Philip, Alicia Y. Toledano, Robert D. Schreiber, and Hans Schreiber PMCID: PMC17568 Medical Sciences Potent selective nonpeptidic inhibitors of human lung tryptase Laurence E. Burgess, Bradley J. Newhouse, Prabha Ibrahim, James Rizzi, Mohammed A. Kashem, Ann Hartman, Barbara J. Brandhuber, Clifford D. Wright, David S. Thomson, Guy P. A. Vigers, and Kevin Koch PMCID: PMC17520 CD8+ minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells Dominique Bonnet, Edus H. Warren, Philip D. Greenberg, John E. Dick, and Stanley R. Riddell PMCID: PMC17569 Defective CTLA-4 cycling pathway in Chediak–Higashi syndrome: A possible mechanism for deregulation of T lymphocyte activation Franck J. Barrat, Françoise Le Deist, Malika Benkerrou, Philippe Bousso, Jérome Feldmann, Alain Fischer, and Geneviève de Saint Basile PMCID: PMC17570 Elevated retinoic acid receptor β4 protein in human breast tumor cells with nuclear and cytoplasmic localization Karen M. Sommer, Lucinda I. Chen, Piper M. Treuting, Lynne T. Smith, and Karen Swisshelm PMCID: PMC17571 Long-term regulated expression of growth hormone in mice after intramuscular gene transfer Victor M. Rivera, Xuehai Ye, Nancy L. Courage, Jeff Sachar, Frank Cerasoli, Jr., James M. Wilson, and Michael Gilman PMCID: PMC17572 Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor Keisuke Abe, Mamoru Shoji, Jiang Chen, Angelika Bierhaus, Indrani Danave, Cornelia Micko, Katherine Casper, Dirck L. Dillehay, Peter P. Nawroth, and Frederick R. Rickles PMCID: PMC17573 Medin: An integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid Bo Häggqvist, Jan Näslund, Knut Sletten, Gunilla T. Westermark, Gerd Mucchiano, Lars O. Tjernberg, Christer Nordstedt, Ulla Engström, and Per Westermark PMCID: PMC17574 JE-2147: A dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1 Kazuhisa Yoshimura, Ryohei Kato, Keisuke Yusa, Mark F. Kavlick, Victor Maroun, Aline Nguyen, Tsutomu Mimoto, Takamasa Ueno, Makoto Shintani, Judith Falloon, Henry Masur, Hideya Hayashi, John Erickson, and Hiroaki Mitsuya PMCID: PMC17575 CpG island methylator phenotype in colorectal cancer Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota, James G. Herman, Stephen B. Baylin, and Jean-Pierre J. Issa PMCID: PMC17576 Transient expression of DNA and RNA in parasitic helminths by using particle bombardment Richard E. Davis, Angelica Parra, Philip T. LoVerde, Eugenia Ribeiro, Gina Glorioso, and Scott Hodgson PMCID: PMC17577 A heterozygous mutation of β-actin associated with neutrophil dysfunction and recurrent infection Hiroyuki Nunoi, Tsuyoshi Yamazaki, Hiroyuki Tsuchiya, Seishi Kato, Harry L. Malech, Ichiro Matsuda, and Shiro Kanegasaki PMCID: PMC17578 Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases Christian Beltinger, Simone Fulda, Thomas Kammertoens, Eric Meyer, Wolfgang Uckert, and Klaus-Michael Debatin PMCID: PMC17579 Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1 Pu Zhang, Gerhard Behre, Jing Pan, Atsushi Iwama, Nawarat Wara-aswapati, Hanna S. Radomska, Philip E. Auron, Daniel G. Tenen, and Zijie Sun PMCID: PMC17580 Cancer dormancy and cell signaling: Induction of p21waf1 initiated by membrane IgM engagement increases survival of B lymphoma cells Radu Marches, Robert Hsueh, and Jonathan W. Uhr PMCID: PMC17581 Microbiology Dynamics of Helicobacter pylori colonization in relation to the host response Martin J. Blaser and Denise Kirschner PMCID: PMC17522 A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum Choukri Ben Mamoun, Ilya Y. Gluzman, Sophie Goyard, Stephen M. Beverley, and Daniel E. Goldberg PMCID: PMC17582 Neurobiology Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury Uwe Scherbel, Ramesh Raghupathi, Michio Nakamura, Kathryn E. Saatman, John Q. Trojanowski, Edmund Neugebauer, Michael W. Marino, and Tracy K. McIntosh PMCID: PMC17583 Transgenic mice expressing a Huntington’s disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity Oskar Hansson, Åsa Petersén, Marcel Leist, Pierluigi Nicotera, Roger F. Castilho, and Patrik Brundin PMCID: PMC17584 Inhibition of uptake unmasks rapid extracellular turnover of glutamate of nonvesicular origin D. Jabaudon, K. Shimamoto, Y. Yasuda-Kamatani, M. Scanziani, B. H. Gähwiler, and U. Gerber PMCID: PMC17585 Novelty acquisition is associated with induction of hippocampal long-term depression Denise Manahan-Vaughan and Karl-Heinz Braunewell PMCID: PMC17586 Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons Elzbieta Chalecka-Franaszek and De-Maw Chuang PMCID: PMC17587 Cross-modal reorganization of callosal connectivity without altering thalamocortical projections Sarah L. Pallas, Thomas Littman, and David R. Moore PMCID: PMC17588 Physiology Intravascular flow decreases erythrocyte consumption of nitric oxide James C. Liao, Travis W. Hein, Mark W. Vaughn, Kuang-Tse Huang, and Lih Kuo PMCID: PMC17589 Plant Biology The violaxanthin cycle protects plants from photooxidative damage by more than one mechanism Michel Havaux and Krishna K. Niyogi PMCID: PMC17590 Targeted manipulation of maize genes in vivo using chimeric RNA/DNA oligonucleotides Tong Zhu, David J. Peterson, Laura Tagliani, Grace St. Clair, Chris L. Baszczynski, and Ben Bowen PMCID: PMC17591 A tool for functional plant genomics: Chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutations Peter R. Beetham, Peter B. Kipp, Xenia L. Sawycky, Charles J. Arntzen, and Gregory D. May PMCID: PMC17592 LOV (light, oxygen, or voltage) domains of the blue-light photoreceptor phototropin (nph1): Binding sites for the chromophore flavin mononucleotide John M. Christie, Michael Salomon, Kazunari Nozue, Masamitsu Wada, and Winslow R. Briggs PMCID: PMC17593 Algae displaying the diadinoxanthin cycle also possess the violaxanthin cycle Martin Lohr and Christian Wilhelm PMCID: PMC17594 Psychology How can we boost IQs of “dull children”?: A late adoption study Michel Duyme, Annick-Camille Dumaret, and Stanislaw Tomkiewicz PMCID: PMC17595 Social Sciences Anthropology Oreopithecus was a bipedal ape after all: Evidence from the iliac cancellous architecture Lorenzo Rook, Luca Bondioli, Meike Köhler, Salvador Moyà-Solà, and Roberto Macchiarelli PMCID: PMC17596 Corrections Proc Natl Acad Sci U S A. 1999 July 20; 96(15): 8800. PMCID: PMC56120 Corrects: List of New Members. Proc Natl Acad Sci U S A. 1999 April 27; 96(9): 4767–4768. Proc Natl Acad Sci U S A. 1999 July 20; 96(15): 8800. PMCID: PMC56121 Corrects: Robert J. McMahon, et al. Regulation of the zinc transporter ZnT-1 by dietary zinc. Proc Natl Acad Sci U S A. 1998 April 28; 95(9): 4841–4846. |
