| | This journal provides immediate access to some articles. Commentaries Fit for life in the immune system? Surrogate L chain tests H chains
that test L chains Fritz Melchers PMCID: PMC33529 A notable cleavage: Winding up with β-amyloid Kenneth S. Kosik PMCID: PMC33530 Heart or hand? Unmasking the basis for specific Holt-Oram phenotypes Michael D. Schneider and Robert J. Schwartz PMCID: PMC33531 More surprises from Kinetoplastida John E. Donelson, Malcolm J. Gardner, and Najib M. El-Sayed PMCID: PMC33532 More on the X files Rosalind M. Harding PMCID: PMC33533 Attention and primary visual cortex Michael I. Posner and Charles D. Gilbert PMCID: PMC33534 The dynamic dialogue between cells and matrices: Implications of
fibronectin’s elasticity Richard O. Hynes PMCID: PMC33535 Physical Sciences Chemistry A hierarchical approach to protein molecular evolution Leonard D. Bogarad and Michael W. Deem PMCID: PMC15812 The topomer-sampling model of protein folding Derek A. Debe, Matt J. Carlson, and William A. Goddard, III PMCID: PMC15813 Femtosecond dynamics of dative bonding: Concepts of reversible and dissociative electron transfer reactions Dongping Zhong and Ahmed H. Zewail PMCID: PMC15814 Protein folding at the air–water interface studied with x-ray reflectivity David Gidalevitz, Zhengqing Huang, and Stuart A. Rice PMCID: PMC15815 Mathematics On the behavior of hyperbolic neutral points in two-dimensional ideal magnetohydrodynamics Diego Cordoba and Christiane Marliani PMCID: PMC15816 Biological Sciences Applied Biological Sciences Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector Alessandra Recchia, Robin J. Parks, Stefania Lamartina, Carlo Toniatti, Luisa Pieroni, Fabio Palombo, Gennaro Ciliberto, Frank L. Graham, Riccardo Cortese, Nicola La Monica, and Stefano Colloca PMCID: PMC15817 Structural characteristics of supramolecular assemblies formed by guanidinium-cholesterol reagents for gene transfection Bruno Pitard, Noufissa Oudrhiri, Jean-Pierre Vigneron, Michelle Hauchecorne, Olivier Aguerre, Renée Toury, Marc Airiau, Rajen Ramasawmy, Daniel Scherman, Joël Crouzet, Jean-Marie Lehn, and Pierre Lehn PMCID: PMC15818 Biochemistry Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling Vassilis Doucas, Marc Tini, David A. Egan, and Ronald M. Evans PMCID: PMC15819 Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling Vassilis Doucas and Ronald M. Evans PMCID: PMC15820 Unique forms of human and mouse nuclear receptor corepressor SMRT Peter Ordentlich, Michael Downes, Wen Xie, Anna Genin, Nancy B. Spinner, and Ronald M. Evans PMCID: PMC15821 Troponin I is present in human cartilage and inhibits angiogenesis Marsha A. Moses, Dmitri Wiederschain, Inmin Wu, Cecilia A. Fernandez, Vahid Ghazizadeh, William S. Lane, Evelyn Flynn, Arthur Sytkowski, Terence Tao, and Robert Langer PMCID: PMC15822 Serine–arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing Klemens J. Hertel and Tom Maniatis PMCID: PMC15823 The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks Ray-Yuan Chuang and Thomas J. Kelly PMCID: PMC15824 Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-Å resolution Vladimir N. Malashkevich, Brian J. Schneider, Margaret L. McNally, Michael A. Milhollen, James X. Pang, and Peter S. Kim PMCID: PMC15825 Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences Luc Gaudreau, Marie Keaveney, Julián Nevado, Zafar Zaman, Gene O. Bryant, Kevin Struhl, and Mark Ptashne PMCID: PMC15826 Transcriptional activation by artificial recruitment in mammalian cells Julián Nevado, Luc Gaudreau, Maryse Adam, and Mark Ptashne PMCID: PMC15827 Lysozyme and RNases as anti-HIV components in β-core preparations of human chorionic gonadotropin Sylvia Lee-Huang, Paul L. Huang, Yongtao Sun, Philip L. Huang, Hsiang-fu Kung, Diana L. Blithe, and Hao-Chia Chen PMCID: PMC15828 GroES in the asymmetric GroEL14–GroES7 complex exchanges via an associative mechanism Paul M. Horowitz, George H. Lorimer, and Jesse Ybarra PMCID: PMC15829 Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum Jung-Keun Suh, Lawrence L. Poulsen, Daniel M. Ziegler, and Jon D. Robertus PMCID: PMC15830 Identification of a transcription factor, encoded by two vaccinia virus early genes, that regulates the intermediate stage of viral gene expression Patrick Sanz and Bernard Moss PMCID: PMC15831 A strategy for rapid sequencing of heparan sulfate and heparin
saccharides Jeremy E. Turnbull, John J. Hopwood, and John T. Gallagher PMCID: PMC15832 HIV-1 Gag shares a signature motif with annexin (Anx7), which is required for virus replication M. Srivastava, M. Cartas, T. A. Rizvi, S. P. Singh, D. Serio, V. S. Kalyanaraman, H. B. Pollard, and A. Srinivasan PMCID: PMC15833 Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis Marco Di Fruscio, Taiping Chen, and Stéphane Richard PMCID: PMC15834 Iron availability dramatically alters the distribution of ferritin subunit messages in Drosophila melanogaster Teodora Georgieva, Boris C. Dunkov, Nedjalka Harizanova, Kiril Ralchev, and John H. Law PMCID: PMC15835 Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat Lars Thim, Peter Kristensen, Per F. Nielsen, Birgitte S. Wulff, and Jes T. Clausen PMCID: PMC15836 Specific interaction of Tat with the human but not rodent P-TEFb complex mediates the species-specific Tat activation of HIV-1 transcription Dan Chen, Yick Fong, and Qiang Zhou PMCID: PMC15837 In vitro suicide inhibition of self-splicing of a
group I intron from Pneumocystis carinii by an N3′ → P5′
phosphoramidate hexanucleotide Stephen M. Testa, Sergei M. Gryaznov, and Douglas H. Turner PMCID: PMC15838 Mutation analysis of the Pip interaction domain reveals critical residues for protein–protein interactions Maria Antonia Ortiz, James Light, Richard A. Maki, and Nuria Assa-Munt PMCID: PMC15839 Phosphorylating DNA with DNA Yingfu Li and Ronald R. Breaker PMCID: PMC15840 Structural basis for the inhibitory effect of brefeldin A on guanine nucleotide-exchange proteins for ADP-ribosylation factors Makoto Sata, Joel Moss, and Martha Vaughan PMCID: PMC15841 Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences David J. Segal, Birgit Dreier, Roger R. Beerli, and Carlos F. Barbas, III PMCID: PMC15842 An activation-specific role for transcription factor TFIIB in vivo Wei-Hua Wu and Michael Hampsey PMCID: PMC15843 Biophysics Protein folding at the air–water interface studied with x-ray reflectivity David Gidalevitz, Zhengqing Huang, and Stuart A. Rice PMCID: PMC15815 Molecular model of muscle contraction T. A. J. Duke PMCID: PMC15844 Interpretation of the spatial charge displacements in bacteriorhodopsin in terms of structural changes during the photocycle András Dér, László Oroszi, Ágnes Kulcsár, László Zimányi, Rudolf Tóth-Boconádi, Lajos Keszthelyi, Walther Stoeckenius, and Pál Ormos PMCID: PMC15845 Multiple pathways on a protein-folding energy landscape: Kinetic evidence Robert A. Goldbeck, Yiren G. Thomas, Eefei Chen, Raymond M. Esquerra, and David S. Kliger PMCID: PMC15846 Cell Biology Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase Regina M. Goetz, Hemant S. Thatte, Prakash Prabhakar, Michael R. Cho, Thomas Michel, and David E. Golan PMCID: PMC15847 The Opitz syndrome gene product, MID1, associates with microtubules Susann Schweiger, John Foerster, Tanja Lehmann, Vanessa Suckow, Yves A. Muller, Gerald Walter, Theresa Davies, Helen Porter, Hans van Bokhoven, Peter W. Lunt, Peter Traub, and Hans-Hilger Ropers PMCID: PMC15848 DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase B. Tibor Roberts, Carol Y. Ying, Jean Gautier, and James L. Maller PMCID: PMC15849 Syndecan-4 signals cooperatively with integrins in a Rhodependent manner in the assembly of focal adhesions and actin stress fibers Stefania Saoncella, Frank Echtermeyer, Fabienne Denhez, Julie K. Nowlen, Deane F. Mosher, Stephen D. Robinson, Richard O. Hynes, and Paul F. Goetinck PMCID: PMC15850 Angiostatin binds ATP synthase on the surface of human endothelial cells Tammy L. Moser, M. Sharon Stack, Iain Asplin, Jan J. Enghild, Peter Højrup, Lorraine Everitt, Susan Hubchak, H. William Schnaper, and Salvatore V. Pizzo PMCID: PMC15851 Cyclin-dependent kinase control of centrosome duplication Kathleen R. Lacey, Peter K. Jackson, and Tim Stearns PMCID: PMC15852 Histidine-tagged wild-type yeast actin: Its properties and use in an approach for obtaining yeast actin mutants Jenny Buzan, Jinyan Du, Tatiana Karpova, and Carl Frieden PMCID: PMC15853 A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division Shi-Ying Cai, Roger W. Babbitt, and Vincent T. Marchesi PMCID: PMC15854 Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function Mei Bai, Sunita Trivedi, Olga Kifor, Stephen J. Quinn, and Edward M. Brown PMCID: PMC15855 Identification of a putative effector protein for rab11 that participates in transferrin recycling Jianbo Zeng, Mindong Ren, Diego Gravotta, Carmen De Lemos-Chiarandini, Mary Lui, Hediye Erdjument-Bromage, Paul Tempst, Genxing Xu, Tian Huai Shen, Takashi Morimoto, Milton Adesnik, and David D. Sabatini PMCID: PMC15856 Essential role of STAT3 for embryonic stem cell pluripotency Regina Raz, Chien-Kuo Lee, Linda A. Cannizzaro, Peter d’Eustachio, and David E. Levy PMCID: PMC15857 The tail domain of lamin Dm0 binds histones H2A and H2B Michal Goldberg, Amnon Harel, Michael Brandeis, Thomas Rechsteiner, Timothy J. Richmond, Aryeh M. Weiss, and Yosef Gruenbaum PMCID: PMC15858 Regulation of endogenous E2F1 stability by the retinoblastoma family proteins Fabio Martelli and David M. Livingston PMCID: PMC15859 Evolution A hierarchical approach to protein molecular evolution Leonard D. Bogarad and Michael W. Deem PMCID: PMC15812 Molecular evidence of cryptic speciation in planktonic foraminifers and their relation to oceanic provinces Colomban de Vargas, Richard Norris, Louisette Zaninetti, Stuart W. Gibb, and Jan Pawlowski PMCID: PMC15860 CORE-SINEs: Eukaryotic short interspersed retroposing elements with common sequence motifs Nicolas Gilbert and Damian Labuda PMCID: PMC15861 X chromosome evidence for ancient human histories Eugene E. Harris and Jody Hey PMCID: PMC15940 Genetics Relative rates of insertion and deletion mutations in a microsatellite sequence in cultured cells Christine D. Twerdi, Jayne C. Boyer, and Rosann A. Farber PMCID: PMC15862 GLI3 mutations in human disorders mimic Drosophila Cubitus interruptus protein functions and localization Sang Hoon Shin, Priit Kogerman, Erika Lindström, Rune Toftgárd, and Leslie G. Biesecker PMCID: PMC15863 A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1 Christine J. Hawkins, Susan L. Wang, and Bruce A. Hay PMCID: PMC15864 Periodical distribution of transcription factor sites in promoter regions and connection with chromatin structure Ilya Ioshikhes, Edward N. Trifonov, and Michael Q. Zhang PMCID: PMC15865 The use of gene clusters to infer functional coupling Ross Overbeek, Michael Fonstein, Mark D’Souza, Gordon D. Pusch, and Natalia Maltsev PMCID: PMC15866 Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes Peter J. Myler, Lindsey Audleman, Theo deVos, Greg Hixson, Patti Kiser, Craig Lemley, Charles Magness, Erika Rickel, Ellen Sisk, Susan Sunkin, Steven Swartzell, Thomas Westlake, Patrick Bastien, Guoliang Fu, Alasdair Ivens, and Kenneth Stuart PMCID: PMC15867 Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation Pablo Tamayo, Donna Slonim, Jill Mesirov, Qing Zhu, Sutisak Kitareewan, Ethan Dmitrovsky, Eric S. Lander, and Todd R. Golub PMCID: PMC15868 Isolation of DNA fragments associated with methylated CpG islands in human adenocarcinomas of the lung using a methylated DNA binding column and denaturing gradient gel electrophoresis Masahiko Shiraishi, Ying H. Chuu, and Takao Sekiya PMCID: PMC15869 Different TBX5 interactions in heart and limb defined by Holt–Oram syndrome mutations Craig T. Basson, Taosheng Huang, Robert C. Lin, David R. Bachinsky, Stanislawa Weremowicz, Alicia Vaglio, Rina Bruzzone, Roberto Quadrelli, Margherita Lerone, Giovanni Romeo, Margherita Silengo, Alexandre Pereira, Jose Krieger, Sonia F. Mesquita, Mitsuhiro Kamisago, Cynthia C. Morton, Mary Ella M. Pierpont, Chistoph W. Müller, J. G. Seidman, and Christine E. Seidman PMCID: PMC15870 Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene Elad B. Gil, Elizabeth Malone Link, Leo X. Liu, Carl D. Johnson, and Jacqueline A. Lees PMCID: PMC15871 A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys–Drash syndrome Charles E. Patek, Melissa H. Little, Stewart Fleming, Colin Miles, Jean-Paul Charlieu, Alan R. Clarke, Kiyoshi Miyagawa, Sheila Christie, Jennifer Doig, David J. Harrison, David J. Porteous, Anthony J. Brookes, Martin L. Hooper, and Nicholas D. Hastie PMCID: PMC15872 Detecting patterns of protein distribution and gene expression in silico Michael T. Geraghty, Doug Bassett, James C. Morrell, Gregory J. Gatto, Jr., Jianwu Bai, Brian V. Geisbrecht, Phil Hieter, and Stephen J. Gould PMCID: PMC15873 Polarity of recombination in transformation of Streptococcus pneumoniae Franck Pasta and Michel A. Sicard PMCID: PMC15874 Abnormalities at 14q32.1 in T cell malignancies involve two oncogenes Yuri Pekarsky, Cora Hallas, Masaharu Isobe, Giandomenico Russo, and Carlo M. Croce PMCID: PMC15875 Mitotic recombination map of 13cen–13q14 derived from an investigation of loss of heterozygosity in retinoblastomas Stephanie A. Hagstrom and Thaddeus P. Dryja PMCID: PMC15876 Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved Allison Weiss, Debra McDonough, Brett Wertman, Leslie Acakpo-Satchivi, Kate Montgomery, Raju Kucherlapati, Leslie Leinwand, and Kenneth Krauter PMCID: PMC15877 Microsatellite instability in Drosophila spellchecker1 (MutS homolog) mutants Carlos Flores and William Engels PMCID: PMC15878 Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene Karin Drotschmann, Alan B. Clark, Hiep T. Tran, Michael A. Resnick, Dmitry A. Gordenin, and Thomas A. Kunkel PMCID: PMC15879 Immunology Functional differences between memory and naive CD8 T cells Bryan K. Cho, Changyu Wang, Satoshi Sugawa, Herman N. Eisen, and Jianzhu Chen PMCID: PMC15880 Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4+ T lymphocytes Willem W. Overwijk, David S. Lee, Deborah R. Surman, Kari R. Irvine, Christopher E. Touloukian, Chi-Chao Chan, Miles W. Carroll, Bernard Moss, Steven A. Rosenberg, and Nicholas P. Restifo PMCID: PMC15881 Stable transduction of quiescent CD34+CD38− human hematopoietic cells by HIV-1-based lentiviral vectors Scott S. Case, Mary A. Price, Craig T. Jordan, Xiao Jin Yu, Lijun Wang, Gerhard Bauer, Dennis L. Haas, Dakun Xu, Renata Stripecke, Luigi Naldini, Donald B. Kohn, and Gay M. Crooks PMCID: PMC15882 Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality Takahiro S. Doi, Michael W. Marino, Toshitada Takahashi, Toshimichi Yoshida, Teruyo Sakakura, Lloyd J. Old, and Yuichi Obata PMCID: PMC15883 Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus Katherine J. Seidl, John P. Manis, Andrea Bottaro, Jue Zhang, Laurie Davidson, Alison Kisselgof, Hans Oettgen, and Frederick W. Alt PMCID: PMC15884 Cyclophilin C-associated protein: A normal secreted glycoprotein that down-modulates endotoxin and proinflammatory responses in vivo Meg Trahey and Irving L. Weissman PMCID: PMC15885 Effective treatment of autoimmune disease and progressive renal disease by mixed bone-marrow transplantation that establishes a stable mixed chimerism in BXSB recipient mice Bingyan Wang, Yoshihisa Yamamoto, Nagwa S. El-Badri, and Robert A. Good PMCID: PMC15886 Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily José M. Casasnovas, Cristiana Pieroni, and Timothy A. Springer PMCID: PMC15887 Intercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cells Claudia R. Luksch, Ola Winqvist, Minette E. Ozaki, Lars Karlsson, Michael R. Jackson, Per A. Peterson, and Susan R. Webb PMCID: PMC15888 In vitro comparison of the antigen-binding and stability properties of the various molecular forms of IgA antibodies assembled and produced in CHO cells José Berdoz, Corinne Tallichet Blanc, Monique Reinhardt, Jean-Pierre Kraehenbuhl, and Blaise Corthésy PMCID: PMC15889 The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-κB pathways Patrick S. Costello, Alice E. Walters, P. Joseph Mee, Martin Turner, Lucinda F. Reynolds, Antonella Prisco, Nitza Sarner, Rose Zamoyska, and Victor L. J. Tybulewicz PMCID: PMC15890 Novel mechanisms control the folding and assembly of λ5/14.1 and VpreB to produce an intact surrogate light chain Yoshiyuki Minegishi, Linda M. Hendershot, and Mary Ellen Conley PMCID: PMC15891 Medical Sciences An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect Jason Chesney, Robert Mitchell, Fabio Benigni, Michael Bacher, Lori Spiegel, Yousef Al-Abed, Jung Hee Han, Christine Metz, and Richard Bucala PMCID: PMC15892 Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein Stefan F. Lichtenthaler, Rong Wang, Heike Grimm, Sacha N. Uljon, Colin L. Masters, and Konrad Beyreuther PMCID: PMC15893 Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes Andrew A. Pieper, Daniel J. Brat, David K. Krug, Crystal C. Watkins, Alok Gupta, Seth Blackshaw, Ajay Verma, Zhao-Qi Wang, and Solomon H. Snyder PMCID: PMC15894 A model for studying megakaryocyte development and biology George J. Murphy and Andrew D. Leavitt PMCID: PMC15895 Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1 Lyn M. Wise, Tanja Veikkola, Andrew A. Mercer, Loreen J. Savory, Stephen B. Fleming, Carol Caesar, Angela Vitali, Taija Makinen, Kari Alitalo, and Steven A. Stacker PMCID: PMC15896 Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53 Weikang Tao and Arnold J. Levine PMCID: PMC15897 Epidermal growth factor system regulates mucin production in airways Kiyoshi Takeyama, Karim Dabbagh, Heung-Man Lee, Carlos Agustí, James A. Lausier, Iris F. Ueki, Kathleen M. Grattan, and Jay A. Nadel PMCID: PMC15898 Transforming growth factor β stimulation of colorectal cancer cell lines: Type II receptor bypass and changes in adhesion molecule expression Mohammad Ilyas, Jason A. Efstathiou, Josef Straub, Hee C. Kim, and Walter F. Bodmer PMCID: PMC15899 Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis Renato V. Iozzo, Fatima Chakrani, Danilo Perrotti, David J. McQuillan, Tomasz Skorski, Bruno Calabretta, and Inge Eichstetter PMCID: PMC15900 Inhibition of growth, production of insulin-like growth factor-II (IGF-II), and expression of IGF-II mRNA of human cancer cell lines by antagonistic analogs of growth hormone-releasing hormone in vitro Valér J. Csernus, Andrew V. Schally, Hippokratis Kiaris, and Patricia Armatis PMCID: PMC15901 Transdermal photopolymerization for minimally invasive implantation J. Elisseeff, K. Anseth, D. Sims, W. McIntosh, M. Randolph, and R. Langer PMCID: PMC15902 Exposure of cryptic epitopes on transthyretin only in amyloid and in amyloidogenic mutants Gundars Goldsteins, Håkan Persson, Karin Andersson, Anders Olofsson, Ingrid Dacklin, Åsa Edvinsson, Maria João Saraiva, and Erik Lundgren PMCID: PMC15903 Molecular cloning and characterization of prostase, an androgen-regulated serine protease with prostate-restricted expression Peter S. Nelson, Lu Gan, Camari Ferguson, Patrick Moss, Richard Gelinas, Leroy Hood, and Kai Wang PMCID: PMC15904 In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells Samuel H. Cheshier, Sean J. Morrison, Xinsheng Liao, and Irving L. Weissman PMCID: PMC15905 Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats Yves Uteza, Jean-Sébastien Rouillot, Alexandra Kobetz, Dominique Marchant, Sèverine Pecqueur, Emmanuelle Arnaud, Hervé Prats, Jiri Honiger, Jean-Louis Dufier, Marc Abitbol, and Martin Neuner-Jehle PMCID: PMC15906 Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia Kenji Ihara, Eiichi Ishii, Mariko Eguchi, Hidetoshi Takada, Aiko Suminoe, Robert A. Good, and Toshiro Hara PMCID: PMC15907 Enhancement of fluid filtration across tumor vessels: Implication for delivery of macromolecules Paolo A. Netti, Leena M. Hamberg, John W. Babich, Diane Kierstead, Wendy Graham, George J. Hunter, Gerald L. Wolf, Alan Fischman, Yves Boucher, and Rakesh K. Jain PMCID: PMC15908 Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1 Robert E. Fleming, Mary C. Migas, XiaoYan Zhou, Jinxing Jiang, Robert S. Britton, Elizabeth M. Brunt, Shunji Tomatsu, Abdul Waheed, Bruce R. Bacon, and William S. Sly PMCID: PMC15909 The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A James B. Lawrence, Claus Oxvig, Michael T. Overgaard, Lars Sottrup-Jensen, Gerald J. Gleich, Lara G. Hays, John R. Yates, III, and Cheryl A. Conover PMCID: PMC15910 Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro Natacha DePaola, Peter F. Davies, William F. Pritchard, Jr., Lucio Florez, Nadeene Harbeck, and Denise C. Polacek PMCID: PMC15911 A model of human phenylalanine metabolism in normal subjects and in phenylketonuric patients Seymour Kaufman PMCID: PMC15912 Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and high-density lipoprotein-cholesterol levels Sanja Levak-Frank, Wolfgang Hofmann, Peter H. Weinstock, Herbert Radner, Wolfgang Sattler, Jan L. Breslow, and Rudolf Zechner PMCID: PMC15913 Microbiology Restriction of major surface protein 2 (MSP2) variants during tick transmission of the ehrlichia Anaplasma marginale Fred R. Rurangirwa, David Stiller, Dorothy M. French, and Guy H. Palmer PMCID: PMC15914 Molecular and biophysical characterization of TT virus: Evidence for a new virus family infecting humans Isa K. Mushahwar, James C. Erker, A. Scott Muerhoff, Thomas P. Leary, John N. Simons, Larry G. Birkenmeyer, Michelle L. Chalmers, Tami J. Pilot-Matias, and Suresh M. Dexai PMCID: PMC15915 Effects of changes in membrane sodium flux on virulence gene expression in Vibrio cholerae Claudia C. Häse and John J. Mekalanos PMCID: PMC15916 The role of an alternative sigma factor in motility and pilus formation in the cyanobacterium Synechocystis sp. strain PCC6803 Devaki Bhaya, Natsu Watanabe, Teruo Ogawa, and Arthur R. Grossman PMCID: PMC15917 Neurobiology A genetic approach to trace neural circuits Lisa F. Horowitz, Jean-Pierre Montmayeur, Yann Echelard, and Linda B. Buck PMCID: PMC15918 Functional repair of motor endplates after botulinum neurotoxin type A poisoning: Biphasic switch of synaptic activity between nerve sprouts and their parent terminals Anton de Paiva, Frédéric A. Meunier, Jordi Molgó, K. Roger Aoki, and J. Oliver Dolly PMCID: PMC15919 Stimulus–secretion coupling in neurohypophysial nerve endings: A role for intravesicular sodium? Sylve Thirion, Jean-Denis Troadec, Natalia B. Pivovarova, Sophie Pagnotta, S. Brian Andrews, Richard D. Leapman, and Ghislain Nicaise PMCID: PMC15920 Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus Steven P. Wilson, David C. Yeomans, Mary Ann Bender, Ying Lu, William F. Goins, and Joseph C. Glorioso PMCID: PMC15921 Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression Christine Pesold, Wen Sheng Liu, Alessandro Guidotti, Erminio Costa, and Hector J. Caruncho PMCID: PMC15922 Induction of utrophin gene expression by heregulin in skeletal muscle cells: Role of the N-box motif and GA binding protein Anthony O. Gramolini, Lindsay M. Angus, Laurent Schaeffer, Edward A. Burton, Jonathon M. Tinsley, Kay E. Davies, Jean-Pierre Changeux, and Bernard J. Jasmin PMCID: PMC15923 Plaque-independent disruption of neural circuits in Alzheimer’s disease mouse models Albert Y. Hsia, Eliezer Masliah, Lisa McConlogue, Gui-Qiu Yu, Gwen Tatsuno, Kang Hu, Dora Kholodenko, Robert C. Malenka, Roger A. Nicoll, and Lennart Mucke PMCID: PMC15924 Modulation of glycine receptors in retinal ganglion cells by zinc Yi Han and Samuel M. Wu PMCID: PMC15925 Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-d-aspartate receptor A. Soren Leonard, Indra A. Lim, Daniel E. Hemsworth, Mary C. Horne, and Johannes W. Hell PMCID: PMC15926 Stimulated changes in localized cerebral energy consumption under anesthesia Robert G. Shulman, Douglas L. Rothman, and Fahmeed Hyder PMCID: PMC15927 The role of immunophilins in mutant superoxide dismutase-1linked familial amyotrophic lateral sclerosis Jean-pyo Lee, H. Clive Palfrey, Vytautas P. Bindokas, Ghanashyam D. Ghadge, Li Ma, Richard J. Miller, and Raymond P. Roos PMCID: PMC15928 Measures of degeneracy and redundancy in biological networks Giulio Tononi, Olaf Sporns, and Gerald M. Edelman PMCID: PMC15929 Evidence for a physical interaction between presenilin and Notch William J. Ray, Min Yao, Petra Nowotny, Jeff Mumm, Wanjiang Zhang, Jane Y. Wu, Raphael Kopan, and Alison M. Goate PMCID: PMC15930 Ca2+/calmodulin-kinase II enhances channel conductance of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors Victor Derkach, Andres Barria, and Thomas R. Soderling PMCID: PMC15931 Pharmacology Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs Daniel L. Simmons, Regina M. Botting, Philip M. Robertson, Matthew L. Madsen, and John R. Vane PMCID: PMC15932 Physiology Insulin increases near-membrane but not global Ca2+ in isolated skeletal muscle Joseph D. Bruton, Abram Katz, and Håkan Westerblad PMCID: PMC15933 Insulin-like growth factor 1 is required for G2 progression in the estradiol-induced mitotic cycle O. O. Adesanya, J. Zhou, C. Samathanam, L. Powell-Braxton, and C. A. Bondy PMCID: PMC15934 Plant Biology EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases Anders Falk, Bart J. Feys, Louise N. Frost, Jonathan D. G. Jones, Michael J. Daniels, and Jane E. Parker PMCID: PMC15935 Channel-mediated high-affinity K+ uptake into guard cells from Arabidopsis Lioubov Brüggemann, Petra Dietrich, Dirk Becker, Ingo Dreyer, Klaus Palme, and Rainer Hedrich PMCID: PMC15936 Population Biology Phenomenological theory of mortality evolution: Its singularities, universality, and superuniversality Mark Ya. Azbel’ PMCID: PMC15937 Declining survival probability threatens the North Atlantic right whale Hal Caswell, Masami Fujiwara, and Solange Brault PMCID: PMC15938 Psychology Spatial attention affects brain activity in human primary visual cortex Sunil P. Gandhi, David J. Heeger, and Geoffrey M. Boynton PMCID: PMC15939 Social Sciences Anthropology X chromosome evidence for ancient human histories Eugene E. Harris and Jody Hey PMCID: PMC15940 Linguistic diversity of the Americas can be reconciled with a recent colonization Daniel Nettle PMCID: PMC15941 Corrections Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3330. PMCID: PMC56052 Corrects: Darius Balciunas, et al. The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression. Proc Natl Acad Sci U S A. 1999 January 19; 96(2): 376–381. Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3330. PMCID: PMC56053 Corrects: Masami Miyamae, et al. Activation of ![[var epsilon]](corehtml/pmc/pmcents/epsiv.gif) protein kinase C correlates with a cardioprotective effect of regular ethanol consumption. Proc Natl Acad Sci U S A. 1998 July 7; 95(14): 8262–8267. Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3330. PMCID: PMC56054 Corrects: Piera Pasinelli, et al. Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase. Proc Natl Acad Sci U S A. 1998 December 22; 95(26): 15763–15768. Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3330. PMCID: PMC56055 Corrects: Don-On Daniel Mak, et al. Inositol 1,4,5-tris-phosphate activation of inositol tris-phosphate receptor Ca2+ channel by ligand tuning of Ca2+ inhibition. Proc Natl Acad Sci U S A. 1998 December 22; 95(26): 15821–15825. Proc Natl Acad Sci U S A. 1999 March 16; 96(6): 3330. PMCID: PMC56056 Corrects: Noriko Takahashi, et al. Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells. Proc Natl Acad Sci U S A. 1999 January 19; 96(2): 760–765. |
