| | This journal provides immediate access to some articles. Editorial PubMed Central: The GenBank of the published literature Richard J. Roberts PMCID: PMC33354 Commentaries Looking for the exit: How do malaria parasites escape from red
blood cells? Lawrence H. Bannister PMCID: PMC33355 The six functions of Agrobacterium VirE2 Doyle V. Ward and Patricia C. Zambryski PMCID: PMC33356 Biomolecular processes in the fast lane Mark A. Ratner PMCID: PMC33357 Ancient DNA and the origin of modern humans John H. Relethford PMCID: PMC33358 Cancer epigenetics takes center stage Andrew P. Feinberg PMCID: PMC33359 Lactic acid: New roles in a new millennium L. Bruce Gladden PMCID: PMC33360 Can mosaic tumor vessels facilitate molecular diagnosis of
cancer? Judah Folkman PMCID: PMC33361 Transmitochondrial mice: Proof of principle and promises Michio Hirano PMCID: PMC33362 Physical Sciences Applied Mathematics From the Cover:
The structure of scientific collaboration networks M. E. J. Newman PMCID: PMC14598 Chemistry A molecular logic gate K. L. Kompa and R. D. Levine PMCID: PMC14599 Biological Sciences Biochemistry Coupling of histone deacetylation to NAD breakdown by the yeast
silencing protein Sir2: Evidence for acetyl transfer from substrate to
an NAD breakdown product Jason C. Tanny and Danesh Moazed PMCID: PMC14600 A dietary source of coenzyme Q is essential for growth of
long-lived Caenorhabditis elegans
clk-1 mutants Tanya Jonassen, Pamela L. Larsen, and Catherine F. Clarke PMCID: PMC14601 The role of rigidity in DNA looping-unlooping by AraC Tara Harmer, Martin Wu, and Robert Schleif PMCID: PMC14602 Catalytic mechanism of quinoprotein methanol dehydrogenase: A
theoretical and x-ray crystallographic investigation Ya-Jun Zheng, Zong-xiang Xia, Zhi-wei Chen, F. Scott Mathews, and Thomas C. Bruice PMCID: PMC14603 A complex signaling module governs the activity of MalT, the
prototype of an emerging transactivator family Olivier Danot PMCID: PMC14604 A subunit of human nuclear RNase P has ATPase activity Yong Li and Sidney Altman PMCID: PMC14605 Cleavage/polyadenylation factor IA associates with the
carboxyl-terminal domain of RNA polymerase II in
Saccharomyces cerevisiae Daniela Barillà, Barbara A. Lee, and Nick J. Proudfoot PMCID: PMC14606 Antioxidant activity of Ferrozine–iron–amino acid complexes Barbara S. Berlett, Rodney L. Levine, P.
Boon Chock, Mordechai Chevion, and Earl R. Stadtman PMCID: PMC14607 Biophysics The “glycogen shunt” in exercising muscle: A role for
glycogen in muscle energetics and fatigue R. G. Shulman and D. L. Rothman PMCID: PMC14608 Refined crystal structure of DsRed, a red fluorescent protein
from coral, at 2.0-Å resolution Daniel Yarbrough, Rebekka M. Wachter, Karen Kallio, Mikhail V. Matz, and S. James Remington PMCID: PMC14609 Stepwise unfolding of titin under force-clamp atomic
force microscopy Andres F. Oberhauser, Paul K. Hansma, Mariano Carrion-Vazquez, and Julio M. Fernandez PMCID: PMC14610 Direct evidence for the participation of gap
junction-mediated intercellular communication in the transmission
of damage signals from α-particle irradiated to nonirradiated
cells Edouard I. Azzam, Sonia M. de Toledo, and John B. Little PMCID: PMC14611 Simultaneous observation of the O—O and Fe—O2
stretching modes in oxyhemoglobins Tapan Kanti Das, Manon Couture, Yannick Ouellet, Michel Guertin, and Denis L. Rousseau PMCID: PMC14612 An Agrobacterium VirE2 channel for transferred-DNA
transport into plant cells Fabrice Dumas, Myriam Duckely, Pawel Pelczar, Patrick Van Gelder, and Barbara Hohn PMCID: PMC14613 Cell Biology Regulating ankyrin dynamics: Roles of sigma-1 receptors Teruo Hayashi and Tsung-Ping Su PMCID: PMC14614 Cleavage of cyclin A at R70/R71 by the bacterial protease OmpT Cain H. Yam, Wai Yi Siu, Daniel Kaganovich, Joan V. Ruderman, and Randy Y. C. Poon PMCID: PMC14615 A family of tissue-specific resistin-like molecules Claire M. Steppan, Elizabeth J. Brown, Christopher M. Wright, Savitha Bhat, Ronadip R. Banerjee, Charlotte Y. Dai, Gregory H. Enders, Debra G. Silberg, Xiaoming Wen, Gary D. Wu, and Mitchell A. Lazar PMCID: PMC14616 LXRs control lipid-inducible expression of the apolipoprotein E
gene in macrophages and adipocytes Bryan A. Laffitte, Joyce J. Repa, Sean B. Joseph, Damien C. Wilpitz, Heidi R. Kast, David J. Mangelsdorf, and Peter Tontonoz PMCID: PMC14617 Cells adapted to the proteasome inhibitor
4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone
require enzymatically active proteasomes for continued survival Michael F. Princiotta, Ulrich Schubert, Weisan Chen, Jack R. Bennink, Jayhyuk Myung, Craig M. Crews, and Jonathan W. Yewdell PMCID: PMC14618 Interaction of Gα12 and Gα13 with the cytoplasmic domain of
cadherin provides a mechanism for β-catenin release Thomas E. Meigs, Timothy A. Fields, David D. McKee, and Patrick J. Casey PMCID: PMC14619 Evolution Genetic architecture of thermal adaptation in
Escherichia coli Michelle M. Riehle, Albert F. Bennett, and Anthony D. Long PMCID: PMC14620 Heterogeneous geographic patterns of nucleotide sequence
diversity between two alcohol dehydrogenase genes in wild
barley (Hordeum vulgare
subspecies spontaneum) Jing-Zhong Lin, Anthony H. D. Brown, and Michael T. Clegg PMCID: PMC14621 From the Cover:
Mitochondrial DNA sequences in ancient Australians: Implications
for modern human origins Gregory J. Adcock, Elizabeth S. Dennis, Simon Easteal, Gavin A. Huttley, Lars S. Jermiin, W. James Peacock, and Alan Thorne PMCID: PMC14622 A model for the emergence of cooperation, interdependence, and
structure in evolving networks Sanjay Jain and Sandeep Krishna PMCID: PMC14623 Function–structure analysis of proteins using covarion-based
evolutionary approaches: Elongation factors Eric A. Gaucher, Michael M. Miyamoto, and Steven A. Benner PMCID: PMC14624 Evolution of hematopoiesis: Three members of the PU.1
transcription factor family in a cartilaginous fish,
Raja eglanteria Michele K. Anderson, Xiao Sun, Ann L. Miracle, Gary W. Litman, and Ellen V. Rothenberg PMCID: PMC14625 Genetics Attractin/Mahogany/Zitter plays a critical role in
myelination of the central nervous system Takashi Kuramoto, Kazuhiro Kitada, Toshihide Inui, Yoshifumi Sasaki, Kazumi Ito, Takao Hase, Saburo Kawagachi, Yoshihiro Ogawa, Kazuwa Nakao, Gregory S. Barsh, Minako Nagao, Toshikazu Ushijima, and Tadao Serikawa PMCID: PMC14626 CpG island protects Rous sarcoma virus-derived vectors integrated
into nonpermissive cells from DNA methylation and transcriptional suppression Ji ![[r with breve]](corehtml/pmc/pmcents/x0072x0306.gif) í Hejnar, Petra Hájková, Ji í Plachý, Daniel Elleder, Volodymyr Stepanets, and Jan Svoboda PMCID: PMC14627 The Bithorax Complex of Drosophila
melanogaster: Underreplication and morphology in
polytene chromosomes Yuri M. Moshkin, Artyom A. Alekseyenko, Valery F. Semeshin, Anne Spierer, Pierre Spierer, Grigoryi F. Makarevich, Elena S. Belyaeva, and Igor F. Zhimulev PMCID: PMC14628 Mutations in the small heterodimer partner gene are associated
with mild obesity in Japanese subjects Hidekazu Nishigori, Hideaki Tomura, Naoko Tonooka, Masao Kanamori, Shirou Yamada, Kimie Sho, Ituro Inoue, Nobuyuki Kikuchi, Kazumichi Onigata, Itaru Kojima, Tomoko Kohama, Kazuya Yamagata, Qin Yang, Yuji Matsuzawa, Takashi Miki, Susumu Seino, Mi-Young Kim, Hueng-Sik Choi, Yoon-Kwang Lee, David D. Moore, and Jun Takeda PMCID: PMC14629 High-throughput development and characterization of a
genomewide collection of gene-based single nucleotide polymorphism
markers by chip-based matrix-assisted laser
desorption/ionization time-of-flight mass spectrometry Kenneth H. Buetow, Michael Edmonson, Richard MacDonald, Robert Clifford, Ping Yip, Jenny Kelley, Daniel P. Little, Robert Strausberg, Hubert Koester, Charles R. Cantor, and Andreas Braun PMCID: PMC14630 A genome survey indicates a possible susceptibility locus for
bipolar disorder on chromosome 22 John R. Kelsoe, M. Anne Spence, Erika Loetscher, Montserrat Foguet, A. Dessa Sadovnick, Ronald A. Remick, Pamela Flodman, Jason Khristich, Zofi Mroczkowski-Parker, John L. Brown, Diane Masser, Sharon Ungerleider, Mark H. Rapaport, William L. Wishart, and Hermann Luebbert PMCID: PMC14631 From the Cover:
Loss of imprinting of the insulin-like growth factor II gene
occurs by biallelic methylation in a core region of
H19-associated CTCF-binding sites in
colorectal cancer Hidewaki Nakagawa, Robert B. Chadwick, Päivi Peltomäki, Christoph Plass, Yusuke Nakamura, and Albert de la Chapelle PMCID: PMC14632 Immunology Evolution of hematopoiesis: Three members of the PU.1
transcription factor family in a cartilaginous fish,
Raja eglanteria Michele K. Anderson, Xiao Sun, Ann L. Miracle, Gary W. Litman, and Ellen V. Rothenberg PMCID: PMC14625 Reduction in CD8+ cell noncytotoxic anti-HIV activity
in individuals receiving highly active antiretroviral therapy during
primary infection Sharon A. Stranford, June C. Ong, Beatriz Martinez-Mariño, Michael Busch, Frederick M. Hecht, James Kahn, and Jay A. Levy PMCID: PMC14633 Soluble CD14 enriched in colostrum and milk induces B cell growth
and differentiation Dominik Filipp, Kamel Alizadeh-Khiavi, Christopher Richardson, Anthony Palma, Nethnapha Paredes, Osamu Takeuchi, Shizuo Akira, and Michael Julius PMCID: PMC14634 Allelic exclusion and differentiation by protein kinase
C-mediated signals in immature thymocytes Alison M. Michie, Jae-Won Soh, Robert G. Hawley, I. Bernard Weinstein, and Juan Carlos Zúñiga-Pflücker PMCID: PMC14635 Medical Sciences Extreme hydrops fetalis and cardiovascular abnormalities in mice
lacking a functional Adrenomedullin gene Kathleen M. Caron and Oliver Smithies PMCID: PMC14636 A fibronectin fragment inhibits tumor growth, angiogenesis,
and metastasis Ming Yi and Erkki Ruoslahti PMCID: PMC14637 A peripheral marker for schizophrenia: Increased levels of
D3 dopamine receptor mRNA in blood lymphocytes Tal Ilani, Dorit Ben-Shachar, Rael D. Strous, Marina Mazor, Ala Sheinkman, Moshe Kotler, and Sara Fuchs PMCID: PMC14638 Serological detection of cutaneous T-cell lymphoma-associated
antigens Stefan Eichmüller, Dirk Usener, Reinhard Dummer, Angelika Stein, Daniela Thiel, and Dirk Schadendorf PMCID: PMC14639 Inhibition of melanoma tumor growth in vivo by
survivin targeting Douglas Grossman, Paul J. Kim, Jeffrey S. Schechner, and Dario C. Altieri PMCID: PMC14640 Point mutations in the murine fumarylacetoacetate hydrolase gene:
Animal models for the human genetic disorder hereditary tyrosinemia
type 1 Jennifer L. Aponte, Gary A. Sega, Loren J. Hauser, Madhu S. Dhar, Catherine M. Withrow, Donald A. Carpenter, Eugene M. Rinchik, Cymbeline T. Culiat, and Dabney K. Johnson PMCID: PMC14641 Conditional immortalization of freshly isolated human mammary
fibroblasts and endothelial cells Michael J. O'Hare, Jacquelyn Bond, Catherine Clarke, Yasuhiro Takeuchi, Amanda J. Atherton, Catherine Berry, John Moody, Andrew R. J. Silver, Derek C. Davies, Amber E. Alsop, A.
Munro Neville, and Parmjit S. Jat PMCID: PMC14642 Microbiology The evolutionary history of chromosomal super-integrons provides
an ancestry for multiresistant integrons Dean A. Rowe-Magnus, Anne-Marie Guerout, Pascaline Ploncard, Broderick Dychinco, Julian Davies, and Didier Mazel PMCID: PMC14643 Macrophage are the principal reservoir and sustain high virus
loads in rhesus macaques after the depletion of CD4+ T
cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1
infections of humans Tatsuhiko Igarashi, Charles R. Brown, Yasuyuki Endo, Alicia Buckler-White, Ronald Plishka, Norbert Bischofberger, Vanessa Hirsch, and Malcolm A. Martin PMCID: PMC14644 Bunyamwera bunyavirus nonstructural protein NSs is a nonessential
gene product that contributes to viral pathogenesis Anne Bridgen, Friedemann Weber, John K. Fazakerley, and Richard M. Elliott PMCID: PMC14645 Antigenic and genetic heterogeneity of Borrelia
burgdorferi populations transmitted by ticks Jun Ohnishi, Joseph Piesman, and Aravinda M. de Silva PMCID: PMC14646 Neurobiology INAUGURAL ARTICLE by a Recently Elected Academy Member: A default mode of brain function Marcus E. Raichle, Ann Mary MacLeod, Abraham Z. Snyder, William J. Powers, Debra A. Gusnard, and Gordon L. Shulman PMCID: PMC14647 Emotion-induced changes in human medial prefrontal cortex: I.
During cognitive task performance Joseph R. Simpson, Jr., Abraham Z. Snyder, Debra A. Gusnard, and Marcus E. Raichle PMCID: PMC14648 Emotion-induced changes in human medial prefrontal cortex: II.
During anticipatory anxiety Joseph R. Simpson, Jr., Wayne C. Drevets, Abraham Z. Snyder, Debra A. Gusnard, and Marcus E. Raichle PMCID: PMC14649 Dynamic imaging of coherent sources: Studying neural
interactions in the human brain J. Gross, J. Kujala, M. Hämäläinen, L. Timmermann, A. Schnitzler, and R. Salmelin PMCID: PMC14650 Reproduction-related behaviors of Swiss–Webster female mice
living in a cold environment Johnny Chan, Sonoko Ogawa, and Donald
W. Pfaff PMCID: PMC14651 A mechanism for combinatorial regulation of electrical
activity: Potassium channel subunits capable of functioning as
Src homology 3-dependent adaptors Michael N. Nitabach, D. Alberto Llamas, Ricardo C. Araneda, Joanne L. Intile, Ian J. Thompson, Yi I. Zhou, and Todd C. Holmes PMCID: PMC14652 From the Cover:
Acid-sensing ion channel 3 matches the acid-gated current in
cardiac ischemia-sensing neurons Stephani P. Sutherland, Christopher J. Benson, John P. Adelman, and Edwin W. McCleskey PMCID: PMC14653 Pharmacology Regulating ankyrin dynamics: Roles of sigma-1 receptors Teruo Hayashi and Tsung-Ping Su PMCID: PMC14614 Estradiol rapidly inhibits soluble guanylyl cyclase expression in
rat uterus Joshua S. Krumenacker, Salman M. Hyder, and Ferid Murad PMCID: PMC14654 Physiology From the Cover:
Shaking up glycolysis: Sustained, high lactate flux during
aerobic rattling William F. Kemper, Stan L. Lindstedt, Lynn K. Hartzler, James W. Hicks, and Kevin E. Conley PMCID: PMC14655 A mechanism for ATP-sensitive potassium channel diversity:
Functional coassembly of two pore-forming subunits Yi Cui, Jonathan P. Giblin, Lucie H. Clapp, and Andrew Tinker PMCID: PMC14656 Myoglobin: A scavenger of bioactive NO Ulrich Flögel, Marc W. Merx, Axel Gödecke, Ulrich K. M. Decking, and Jürgen Schrader PMCID: PMC14657 Plant Biology Activation of a mitogen-activated protein kinase pathway is
involved in disease resistance in tobacco Kwang-Yeol Yang, Yidong Liu, and Shuqun Zhang PMCID: PMC14658 In planta sequential hydroxylation and
glycosylation of a fungal phytotoxin: Avoiding cell death and
overcoming the fungal invader M. S. C. Pedras, I. L. Zaharia, Y. Gai, Y. Zhou, and D. E. Ward PMCID: PMC14659 Accumulation of soluble and wall-bound indolic metabolites in
Arabidopsis thaliana leaves infected with virulent
or avirulent Pseudomonas syringae pathovar tomato strains Jens Hagemeier, Bernd Schneider, Neil J. Oldham, and Klaus Hahlbrock PMCID: PMC14660 Essential role of the small GTPase Rac in disease resistance
of rice Eiichiro Ono, Hann Ling Wong, Tsutomu Kawasaki, Morifumi Hasegawa, Osamu Kodama, and Ko Shimamoto PMCID: PMC14661 Regulation of starch accumulation by granule-associated plant
14-3-3 proteins Paul C. Sehnke, Hwa-Jee Chung, Ke Wu, and Robert J. Ferl PMCID: PMC14662 The Arabidopsis-accelerated cell death gene
ACD2 encodes red chlorophyll catabolite reductase and
suppresses the spread of disease symptoms Jennifer M. Mach, Andrea R. Castillo, Rebecca Hoogstraten, and Jean T. Greenberg PMCID: PMC14663 Corrections Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 777. Published online 2001 January 9. PMCID: PMC55928 Corrects: Ugo Mayor, et al. Protein folding and unfolding in microseconds to nanoseconds by
experiment and simulation. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13518–13522. Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 777. PMCID: PMC55929 Corrects: Katrin G. Heinze, et al. Simultaneous two-photon excitation of distinct labels for dual-color fluorescence crosscorrelation analysis. Proc Natl Acad Sci U S A. 2000 September 12; 97(19): 10377–10382. Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 777. PMCID: PMC55930 Corrects: Joshua B. Plotkin, et al. Predicting species diversity in tropical forests. Proc Natl Acad Sci U S A. 2000 September 26; 97(20): 10850–10854. Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 777. PMCID: PMC55931 Corrects: Karen S. Aboody, et al. From the Cover:
Neural stem cells display extensive tropism for pathology in
adult brain: Evidence from intracranial gliomas. Proc Natl Acad Sci U S A. 2000 November 7; 97(23): 12846–12851. Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 777. Published online 2001 January 9. PMCID: PMC55932 Corrects: Hans-Otto Karnath, et al. The neural representation of postural control in humans. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13931–13936. |
