| | This journal provides immediate access to some articles. Commentary New technology may reveal mechanisms of radiation resistance in Deinococcus radiodurans Jan Mrázek Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10943–10944. Published online 2002 August 12. doi: 10.1073/pnas.182429699.PMCID: PMC129299 Perspective How does ATP hydrolysis control actin's associations? Elena P. Sablin, John F. Dawson, Margaret S. VanLoock, James A. Spudich, Edward H. Egelman, and Robert J. Fletterick Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10945–10947. Published online 2002 August 7. doi: 10.1073/pnas.152329899.PMCID: PMC123189 Physical Sciences Applied Mathematics Transitions between dynamical states of differing stability in the human brain Andreas Meyer-Lindenberg, Ulf Ziemann, Göran Hajak, Leonardo Cohen, and Karen Faith Berman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10948–10953. Published online 2002 July 31. doi: 10.1073/pnas.162114799.PMCID: PMC123190 Applied Physical Sciences DNA detection using water-soluble conjugated polymers and peptide nucleic acid probes Brent S. Gaylord, Alan J. Heeger, and Guillermo C. Bazan Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10954–10957. Published online 2002 August 7. doi: 10.1073/pnas.162375999.PMCID: PMC123191 Chemistry The reduction potential of nitric oxide (NO) and its importance to NO biochemistry Michael D. Bartberger, Wei Liu, Eleonora Ford, Katrina M. Miranda, Christopher Switzer, Jon M. Fukuto, Patrick J. Farmer, David A. Wink, and Kendall N. Houk Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10958–10963. Published online 2002 August 12. doi: 10.1073/pnas.162095599.PMCID: PMC123192 Hydration at the surface of the protein Monellin: Dynamics with femtosecond resolution Jorge Peon, Samir Kumar Pal, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10964–10969. Published online 2002 August 12. doi: 10.1073/pnas.162366099.PMCID: PMC123193 From the Cover: Are Pfiesteria species toxicogenic? Evidence against production of ichthyotoxins by Pfiesteria shumwayae J. P. Berry, K. S. Reece, K. S. Rein, D. G. Baden, L. W. Haas, W. L. Ribeiro, J. D. Shields, R. V. Snyder, W. K. Vogelbein, and R. E. Gawley Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10970–10975. Published online 2002 August 5. doi: 10.1073/pnas.172221699.PMCID: PMC123194 The evolution of multicomponent systems at high pressures: VI. The thermodynamic stability of the hydrogen–carbon system: The genesis of hydrocarbons and the origin of petroleum J. F. Kenney, Vladimir A. Kutcherov, Nikolai A. Bendeliani, and Vladimir A. Alekseev Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10976–10981. Published online 2002 August 12. doi: 10.1073/pnas.172376899.PMCID: PMC123195 Interchain vs. intrachain energy transfer in acceptor-capped conjugated polymers D. Beljonne, G. Pourtois, C. Silva, E. Hennebicq, L. M. Herz, R. H. Friend, G. D. Scholes, S. Setayesh, K. Müllen, and J. L. Brédas Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10982–10987. Published online 2002 August 12. doi: 10.1073/pnas.172390999.PMCID: PMC123196 Mass-independent fractionation of oxygen isotopes during thermal decomposition of carbonates Martin F. Miller, Ian A. Franchi, Mark H. Thiemens, Teresa L. Jackson, André Brack, Gero Kurat, and Colin T. Pillinger Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10988–10993. Published online 2002 August 7. doi: 10.1073/pnas.172378499.PMCID: PMC123197 Engineering INAUGURAL ARTICLE by a Recently Elected Academy Member: FAST CARS: Engineering a laser spectroscopic technique for rapid identification of bacterial spores M. O. Scully, G. W. Kattawar, R. P. Lucht, T. Opatrný, H. Pilloff, A. Rebane, A. V. Sokolov, and M. S. Zubairy Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10994–11001. Published online 2002 August 13. doi: 10.1073/pnas.172290899.PMCID: PMC123198 Geology Arizona porphyry copper/hydrothermal deposits II: Crystal structure of ajoite, (K + Na) 3Cu 20Al 3Si 29O 76(OH) 16![[center dot]](corehtml/pmc/pmcents/middot.gif) ~8H 2O Joseph J. Pluth and Joseph V. Smith Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11002–11005. Published online 2002 August 13. doi: 10.1073/pnas.132391299.PMCID: PMC123199 Mathematics From the Cover: Drops: The collapse of capillary jets Antonio Cordoba, Diego Cordoba, Charles Fefferman, and Marco A. Fontelos Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11006–11007. Published online 2002 August 9. doi: 10.1073/pnas.152318399.PMCID: PMC123200 Physics The evolution of multicomponent systems at high pressures: VI. The thermodynamic stability of the hydrogen–carbon system: The genesis of hydrocarbons and the origin of petroleum J. F. Kenney, Vladimir A. Kutcherov, Nikolai A. Bendeliani, and Vladimir A. Alekseev Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10976–10981. Published online 2002 August 12. doi: 10.1073/pnas.172376899.PMCID: PMC123195 A model for the simultaneous analysis of reflectance spectra and basis factors of Munsell color samples under D65 illumination in three-dimensional Euclidean space A. Kimball Romney and Tarow Indow Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11543–11546. Published online 2002 August 2. doi: 10.1073/pnas.162368999.PMCID: PMC123292 Biological Sciences Anthropology-BS Y genetic data support the Neolithic demic diffusion model Lounès Chikhi, Richard A. Nichols, Guido Barbujani, and Mark A. Beaumont Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11008–11013. Published online 2002 August 7. doi: 10.1073/pnas.162158799.PMCID: PMC123201 Applied Biological Sciences Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence Aikaterini Zoumi, Alvin Yeh, and Bruce J. Tromberg Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11014–11019. Published online 2002 August 12. doi: 10.1073/pnas.172368799.PMCID: PMC123202 Biochemistry Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli Jason W. Chin, Andrew B. Martin, David S. King, Lei Wang, and Peter G. Schultz Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11020–11024. Published online 2002 August 1. doi: 10.1073/pnas.172226299.PMCID: PMC123203 Caspase 3 activity is required for skeletal muscle differentiation Pasan Fernando, John F. Kelly, Kim Balazsi, Ruth S. Slack, and Lynn A. Megeney Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11025–11030. Published online 2002 August 12. doi: 10.1073/pnas.162172899.PMCID: PMC123204 Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence Christoph Seibert, Martine Cadene, Anthony Sanfiz, Brian T. Chait, and Thomas P. Sakmar Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11031–11036. Published online 2002 August 8. doi: 10.1073/pnas.172380899.PMCID: PMC123205 ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence Joel R. Hoskins, Katsuhiko Yanagihara, Kiyoshi Mizuuchi, and Sue Wickner Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11037–11042. Published online 2002 August 12. doi: 10.1073/pnas.172378899.PMCID: PMC123206 Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster James T. Warren, Anna Petryk, Guillermo Marqués, Michael Jarcho, Jean-Philippe Parvy, Chantal Dauphin-Villemant, Michael B. O'Connor, and Lawrence I. Gilbert Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11043–11048. Published online 2002 August 12. doi: 10.1073/pnas.162375799.PMCID: PMC123207 From the Cover: Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags Mary S. Lipton, Ljiljana Paša-Tolić, Gordon A. Anderson, David J. Anderson, Deanna L. Auberry, John R. Battista, Michael J. Daly, Jim Fredrickson, Kim K. Hixson, Heather Kostandarithes, Christophe Masselon, Lye Meng Markillie, Ronald J. Moore, Margaret F. Romine, Yufeng Shen, Eric Stritmatter, Nikola Tolić, Harold R. Udseth, Amudhan Venkateswaran, Kwong-Kwok Wong, Rui Zhao, and Richard D. Smith Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11049–11054. Published online 2002 August 12. doi: 10.1073/pnas.172170199.PMCID: PMC129300 Interactions between lipids and bacterial reaction centers determined by protein crystallography A. Camara-Artigas, D. Brune, and J. P. Allen Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11055–11060. Published online 2002 August 7. doi: 10.1073/pnas.162368399.PMCID: PMC123209 Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis Phuong Pham, Erica M. Seitz, Sergei Saveliev, Xuan Shen, Roger Woodgate, Michael M. Cox, and Myron F. Goodman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11061–11066. Published online 2002 August 12. doi: 10.1073/pnas.172197099.PMCID: PMC123210 NusA-stimulated RNA polymerase pausing and termination participates in the Bacillus subtilis trp operon attenuation mechanism in vitro Alexander V. Yakhnin and Paul Babitzke Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11067–11072. Published online 2002 August 2. doi: 10.1073/pnas.162373299.PMCID: PMC123211 A genotyping strategy based on incorporation and cleavage of chemically modified nucleotides Jia Liu Wolfe, Tomohiko Kawate, David A. Sarracino, Martin Zillmann, Jeffrey Olson, Vincent P. Stanton, Jr., and Gregory L. Verdine Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11073–11078. Published online 2002 August 8. doi: 10.1073/pnas.162346699.PMCID: PMC123212 Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism Trevor P. Baglin, Robin W. Carrell, Frank C. Church, Charles T. Esmon, and James A. Huntington Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11079–11084. Published online 2002 August 8. doi: 10.1073/pnas.162232399.PMCID: PMC123213 CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90 Stefan Rüdiger, Stefan M. V. Freund, Dmitry B. Veprintsev, and Alan R. Fersht Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11085–11090. Published online 2002 August 5. doi: 10.1073/pnas.132393699.PMCID: PMC123214 Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing Jessica L. Childs, Matthew D. Disney, and Douglas H. Turner Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11091–11096. Published online 2002 August 8. doi: 10.1073/pnas.172391199.PMCID: PMC123215 Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists Anne-Sophie Bessis, Philippe Rondard, Florence Gaven, Isabelle Brabet, Nicolas Triballeau, Laurent Prézeau, Francine Acher, and Jean-Philippe Pin Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11097–11102. Published online 2002 July 31. doi: 10.1073/pnas.162138699.PMCID: PMC123216 Transition to the open state of the TolC periplasmic tunnel entrance Christian Andersen, Eva Koronakis, Evert Bokma, Jeyanthy Eswaran, Daniel Humphreys, Colin Hughes, and Vassilis Koronakis Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11103–11108. Published online 2002 August 5. doi: 10.1073/pnas.162039399.PMCID: PMC123217 Dimerization of cotton fiber cellulose synthase catalytic subunits occurs via oxidation of the zinc-binding domains Isaac Kurek, Yasushi Kawagoe, Deborah Jacob-Wilk, Monika Doblin, and Deborah Delmer Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11109–11114. Published online 2002 August 1. doi: 10.1073/pnas.162077099.PMCID: PMC123218 Transplanting allosteric control of enzyme activity by protein–protein interactions: Coupling a regulatory site to the conserved catalytic core Aaron C. Pawlyk and Donald W. Pettigrew Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11115–11120. Published online 2002 August 2. doi: 10.1073/pnas.132393599.PMCID: PMC123219 tRNA-mediated transcription antitermination in vitro: Codon–anticodon pairing independent of the ribosome Frank J. Grundy, Wade C. Winkler, and Tina M. Henkin Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11121–11126. Published online 2002 August 6. doi: 10.1073/pnas.162366799.PMCID: PMC123220 Focusing of nitric oxide mediated nitrosation and oxidative nitrosylation as a consequence of reaction with superoxide Michael G. Espey, Douglas D. Thomas, Katrina M. Miranda, and David A. Wink Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11127–11132. Published online 2002 August 12. doi: 10.1073/pnas.152157599.PMCID: PMC123221 A −1 ribosomal frameshift element that requires base pairing across four kilobases suggests a mechanism of regulating ribosome and replicase traffic on a viral RNA Jennifer K. Barry and W. Allen Miller Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11133–11138. Published online 2002 July 30. doi: 10.1073/pnas.162223099.PMCID: PMC123222 Profiling protein function with small molecule microarrays Nicolas Winssinger, Scott Ficarro, Peter G. Schultz, and Jennifer L. Harris Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11139–11144. Published online 2002 August 7. doi: 10.1073/pnas.172286899.PMCID: PMC123223 Biophysics Hydration at the surface of the protein Monellin: Dynamics with femtosecond resolution Jorge Peon, Samir Kumar Pal, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10964–10969. Published online 2002 August 12. doi: 10.1073/pnas.162366099.PMCID: PMC123193 Enzymology below 200 K: The kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase Derren J. Heyes, Alexander V. Ruban, Helen M. Wilks, and C. Neil Hunter Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11145–11150. Published online 2002 August 12. doi: 10.1073/pnas.182274199.PMCID: PMC123224 Cosolvent-induced transformation of a death domain tertiary structure Tsan Xiao, Kevin H. Gardner, and Stephen R. Sprang Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11151–11156. Published online 2002 August 12. doi: 10.1073/pnas.172188399.PMCID: PMC123225 Toward predicting protein topology: An approach to identifying β hairpins Xavier de la Cruz, E. Gail Hutchinson, Adrian Shepherd, and Janet M. Thornton Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11157–11162. Published online 2002 August 12. doi: 10.1073/pnas.162376199.PMCID: PMC123226 Designability of α-helical proteins Eldon G. Emberly, Ned S. Wingreen, and Chao Tang Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11163–11168. Published online 2002 August 12. doi: 10.1073/pnas.162105999.PMCID: PMC123227 DNA-dependent divalent cation binding in the nucleosome core particle Curt A. Davey and Timothy J. Richmond Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11169–11174. Published online 2002 August 8. doi: 10.1073/pnas.172271399.PMCID: PMC123228 The ensemble folding kinetics of protein G from an all-atom Monte Carlo simulation Jun Shimada and Eugene I. Shakhnovich Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11175–11180. Published online 2002 August 6. doi: 10.1073/pnas.162268099.PMCID: PMC123229 Cell Biology Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice Andrew I. Su, Luca G. Guidotti, John Paul Pezacki, Francis V. Chisari, and Peter G. Schultz Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11181–11186. Published online 2002 August 12. doi: 10.1073/pnas.122359899.PMCID: PMC123230 Inducible expression of FGF-3 in mouse mammary gland Elly S. W. Ngan, Zhi-Qing Ma, Steven S. Chua, Francesco J. DeMayo, and Sophia Y. Tsai Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11187–11192. Published online 2002 August 8. doi: 10.1073/pnas.172366199.PMCID: PMC123231 Mechanism of caveolin filament assembly Imma Fernandez, Yunshu Ying, Joseph Albanesi, and Richard G. W. Anderson Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11193–11198. Published online 2002 August 7. doi: 10.1073/pnas.172196599.PMCID: PMC123232 A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination Stéphan Gasca, Joaquin Cañizares, Pascal de Santa Barbara, Catherine Méjean, Francis Poulat, Philippe Berta, and Brigitte Boizet-Bonhoure Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11199–11204. Published online 2002 August 8. doi: 10.1073/pnas.172383099.PMCID: PMC123233 From the Cover: Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo Ivan B. Lobov, Peter C. Brooks, and Richard A. Lang Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11205–11210. Published online 2002 August 5. doi: 10.1073/pnas.172161899.PMCID: PMC123234 Lack of acrosome formation in mice lacking a Golgi protein, GOPC Ryoji Yao, Chizuru Ito, Yasuko Natsume, Yoshinobu Sugitani, Hitomi Yamanaka, Shoji Kuretake, Kaoru Yanagida, Akira Sato, Kiyotaka Toshimori, and Tetsuo Noda Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11211–11216. Published online 2002 July 30. doi: 10.1073/pnas.162027899.PMCID: PMC123235 Developmental Biology The anaphase promoting complex/cyclosome is required during development for modified cell cycles Helena Kashevsky, Julie A. Wallace, Bruce H. Reed, Cary Lai, Aki Hayashi-Hagihara, and Terry L. Orr-Weaver Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11217–11222. Published online 2002 August 8. doi: 10.1073/pnas.172391099.PMCID: PMC123236 Ecology From the Cover: Are Pfiesteria species toxicogenic? Evidence against production of ichthyotoxins by Pfiesteria shumwayae J. P. Berry, K. S. Reece, K. S. Rein, D. G. Baden, L. W. Haas, W. L. Ribeiro, J. D. Shields, R. V. Snyder, W. K. Vogelbein, and R. E. Gawley Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10970–10975. Published online 2002 August 5. doi: 10.1073/pnas.172221699.PMCID: PMC123194 Disarming the mustard oil bomb Andreas Ratzka, Heiko Vogel, Daniel J. Kliebenstein, Thomas Mitchell-Olds, and Juergen Kroymann Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11223–11228. Published online 2002 August 2. doi: 10.1073/pnas.172112899.PMCID: PMC123237 Extinction rates under nonrandom patterns of habitat loss Eric W. Seabloom, Andy P. Dobson, and David M. Stoms Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11229–11234. Published online 2002 August 12. doi: 10.1073/pnas.162064899.PMCID: PMC123238 Adverse effects of acid rain on the distribution of the Wood Thrush Hylocichla mustelina in North America Ralph S. Hames, Kenneth V. Rosenberg, James D. Lowe, Sara E. Barker, and André A. Dhondt Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11235–11240. Published online 2002 August 12. doi: 10.1073/pnas.172700199.PMCID: PMC123239 Biodiversity, population regulation, and the stability of coral-reef fish communities Mark H. Carr, Todd W. Anderson, and Mark A. Hixon Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11241–11245. Published online 2002 August 12. doi: 10.1073/pnas.162653499.PMCID: PMC123240 Evolution A phylogenetic analysis of myosin heavy chain type II sequences corroborates that Acoela and Nemertodermatida are basal bilaterians I. Ruiz-Trillo, J. Paps, M. Loukota, C. Ribera, U. Jondelius, J. Baguñà, and M. Riutort Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11246–11251. Published online 2002 August 12. doi: 10.1073/pnas.172390199.PMCID: PMC123241 Reconsidering the null hypothesis: Is maternal rank associated with birth sex ratios in primate groups? Gillian R. Brown and Joan B. Silk Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11252–11255. Published online 2002 August 12. doi: 10.1073/pnas.162360599.PMCID: PMC123242 Hybrid Tamarix widespread in U.S. invasion and undetected in native Asian range John F. Gaskin and Barbara A. Schaal Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11256–11259. Published online 2002 August 12. doi: 10.1073/pnas.132403299.PMCID: PMC123243 MHC heterozygosity confers a selective advantage against multiple-strain infections Dustin J. Penn, Kristy Damjanovich, and Wayne K. Potts Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11260–11264. Published online 2002 August 12. doi: 10.1073/pnas.162006499.PMCID: PMC123244 Genealogical evidence for epidemics of selfish genes Pär K. Ingvarsson and Douglas R. Taylor Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11265–11269. Published online 2002 August 12. doi: 10.1073/pnas.172318099.PMCID: PMC123245 Genetic variation for disease resistance and tolerance among Arabidopsis thaliana accessions Paula X. Kover and Barbara A. Schaal Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11270–11274. Published online 2002 August 9. doi: 10.1073/pnas.102288999.PMCID: PMC123246 The chloroplast and mitochondrial genome sequences of the charophyte Chaetosphaeridium globosum: Insights into the timing of the events that restructured organelle DNAs within the green algal lineage that led to land plants Monique Turmel, Christian Otis, and Claude Lemieux Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11275–11280. Published online 2002 August 2. doi: 10.1073/pnas.162203299.PMCID: PMC123247 Genetics An improved genetic model generates high-resolution mapping of QTL for protein quality in maize endosperm Rongling Wu, Xiang-Yang Lou, Chang-Xing Ma, Xuelu Wang, Brian A. Larkins, and George Casella Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11281–11286. Published online 2002 August 12. doi: 10.1073/pnas.112345699.PMCID: PMC123248 An anatomy of normal and malignant gene expression Kathy Boon, Elisson C. Osório, Susan F. Greenhut, Carl F. Schaefer, Jennifer Shoemaker, Kornelia Polyak, Patrice J. Morin, Kenneth H. Buetow, Robert L. Strausberg, Sandro J. de Souza, and Gregory J. Riggins Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11287–11292. Published online 2002 July 15. doi: 10.1073/pnas.152324199.PMCID: PMC123249 Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis Harry C. Hwang, Carla P. Martins, Yvon Bronkhorst, Erin Randel, Anton Berns, Matthew Fero, and Bruce E. Clurman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11293–11298. Published online 2002 July 31. doi: 10.1073/pnas.162356099.PMCID: PMC123250 Multiple genetic loci modify susceptibility to plasmacytoma-related morbidity in Eμ-v-abl transgenic mice R. C. Andrew Symons, Mark J. Daly, Jane Fridlyand, Terence P. Speed, Wendy D. Cook, Steven Gerondakis, Alan W. Harris, and Simon J. Foote Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11299–11304. Published online 2002 July 30. doi: 10.1073/pnas.162566999.PMCID: PMC123251 Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila Malte Peters, Carmela DeLuca, Atsushi Hirao, Vuk Stambolic, Julia Potter, Lily Zhou, Jennifer Liepa, Bryan Snow, Sudha Arya, Jorge Wong, Denis Bouchard, Richard Binari, Armen S. Manoukian, and Tak W. Mak Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11305–11310. Published online 2002 August 9. doi: 10.1073/pnas.172382899.PMCID: PMC123252 A nonsense mutation in the gene encoding 2′-5′-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice Tomoji Mashimo, Marianne Lucas, Dominique Simon-Chazottes, Marie-Pascale Frenkiel, Xavier Montagutelli, Pierre-Emmanuel Ceccaldi, Vincent Deubel, Jean-Louis Guénet, and Philippe Desprès Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11311–11316. Published online 2002 August 19. doi: 10.1073/pnas.172195399.PMCID: PMC123253 Mismatch-targeted transposition of Mu: A new strategy to map genetic polymorphism Katsuhiko Yanagihara and Kiyoshi Mizuuchi Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11317–11321. Published online 2002 August 12. doi: 10.1073/pnas.132403399.PMCID: PMC123254 Immunology Disruption of pre-TCR expression accelerates lymphomagenesis in E2A-deficient mice Isaac Engel and Cornelis Murre Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11322–11327. Published online 2002 August 9. doi: 10.1073/pnas.162373999.PMCID: PMC123255 Identification of HLA-E-specific alloreactive T lymphocytes: A cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells Chiara Romagnani, Gabriella Pietra, Michela Falco, Enrico Millo, Paola Mazzarino, Roberto Biassoni, Alessandro Moretta, Lorenzo Moretta, and Maria Cristina Mingari Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11328–11333. Published online 2002 August 7. doi: 10.1073/pnas.172369799.PMCID: PMC123256 Deletion of immunoglobulin β in developing B cells leads to cell death Eric Meffre and Michel C. Nussenzweig Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11334–11339. Published online 2002 August 6. doi: 10.1073/pnas.172369999.PMCID: PMC123257 IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions Hiroshi Konishi, Hiroko Tsutsui, Takaaki Murakami, Shizue Yumikura-Futatsugi, Kei-ichi Yamanaka, Minoru Tanaka, Yohichiro Iwakura, Noboru Suzuki, Kiyoshi Takeda, Shizuo Akira, Kenji Nakanishi, and Hitoshi Mizutani Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11340–11345. Published online 2002 July 31. doi: 10.1073/pnas.152337799.PMCID: PMC123258 Potent neutralization of botulinum neurotoxin by recombinant oligoclonal antibody A. Nowakowski, C. Wang, D. B. Powers, P. Amersdorfer, T. J. Smith, V. A. Montgomery, R. Sheridan, R. Blake, L. A. Smith, and J. D. Marks Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11346–11350. Published online 2002 August 12. doi: 10.1073/pnas.172229899.PMCID: PMC123259 Wiskott–Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses Jordan S. Orange, Narayanaswamy Ramesh, Eileen Remold-O'Donnell, Yoji Sasahara, Louise Koopman, Michael Byrne, Francisco A. Bonilla, Fred S. Rosen, Raif S. Geha, and Jack L. Strominger Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11351–11356. Published online 2002 August 12. doi: 10.1073/pnas.162376099.PMCID: PMC123260 Medical Sciences PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice Bradley A. Zinker, Cristina M. Rondinone, James M. Trevillyan, Rebecca J. Gum, Jill E. Clampit, Jeffrey F. Waring, Nancy Xie, Denise Wilcox, Peer Jacobson, Leigh Frost, Paul E. Kroeger, Regina M. Reilly, Sandra Koterski, Terry J. Opgenorth, Roger G. Ulrich, Seth Crosby, Madeline Butler, Susan F. Murray, Robert A. McKay, Sanjay Bhanot, Brett P. Monia, and Michael R. Jirousek Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11357–11362. Published online 2002 August 8. doi: 10.1073/pnas.142298199.PMCID: PMC123261 Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes Beate Fiedler, Suzanne M. Lohmann, Albert Smolenski, Stephan Linnemüller, Burkert Pieske, Frank Schröder, Jeffery D. Molkentin, Helmut Drexler, and Kai C. Wollert Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11363–11368. Published online 2002 August 12. doi: 10.1073/pnas.162100799.PMCID: PMC123262 High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells Xin Huang, Susanne M. Gollin, Siva Raja, and Tony E. Godfrey Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11369–11374. Published online 2002 August 9. doi: 10.1073/pnas.172285799.PMCID: PMC123263 Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice You-Yang Zhao, Yang Liu, Radu-Virgil Stan, Lian Fan, Yusu Gu, Nancy Dalton, Po-Hsien Chu, Kirk Peterson, John Ross, Jr., and Kenneth R. Chien Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11375–11380. Published online 2002 August 12. doi: 10.1073/pnas.172360799.PMCID: PMC123264 A role for the melanocortin 4 receptor in sexual function Lex H. T. Van der Ploeg, William J. Martin, Andrew D. Howard, Ravi P. Nargund, Christopher P. Austin, Xiaoming Guan, Jennifer Drisko, Doreen Cashen, Iyassu Sebhat, Arthur A. Patchett, David J. Figueroa, Anthony G. DiLella, Brett M. Connolly, David H. Weinberg, Carina P. Tan, Oksana C. Palyha, Sheng-Shung Pong, Tanya MacNeil, Charles Rosenblum, Aurawan Vongs, Rui Tang, Hong Yu, Andreas W. Sailer, Tung Ming Fong, Cathy Huang, Michael R. Tota, Ray S. Chang, Ralph Stearns, Constantin Tamvakopoulos, George Christ, Deborah L. Drazen, Brian D. Spar, Randy J. Nelson, and D. Euan MacIntyre Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11381–11386. Published online 2002 August 9. doi: 10.1073/pnas.172378699.PMCID: PMC123265 The gene expression fingerprint of human heart failure Fen-Lai Tan, Christine S. Moravec, Jianbo Li, Carolyn Apperson-Hansen, Patrick M. McCarthy, James B. Young, and Meredith Bond Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11387–11392. Published online 2002 August 12. doi: 10.1073/pnas.162370099.PMCID: PMC123266 VEGF-Trap: A VEGF blocker with potent antitumor effects Jocelyn Holash, Sam Davis, Nick Papadopoulos, Susan D. Croll, Lillian Ho, Michelle Russell, Patricia Boland, Ray Leidich, Donna Hylton, Elena Burova, Ella Ioffe, Tammy Huang, Czeslaw Radziejewski, Kevin Bailey, James P. Fandl, Tom Daly, Stanley J. Wiegand, George D. Yancopoulos, and John S. Rudge Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11393–11398. Published online 2002 August 12. doi: 10.1073/pnas.172398299.PMCID: PMC123267 Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma Eugene S. Kim, Anna Serur, Jianzhong Huang, Christina A. Manley, Kimberly W. McCrudden, Jason S. Frischer, Samuel Z. Soffer, Laurence Ring, Tamara New, Stephanie Zabski, John S. Rudge, Jocelyn Holash, George D. Yancopoulos, Jessica J. Kandel, and Darrell J. Yamashiro Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11399–11404. Published online 2002 August 12. doi: 10.1073/pnas.172398399.PMCID: PMC123268 Microbiology Detergent extraction identifies different VirB protein subassemblies of the type IV secretion machinery in the membranes of Agrobacterium tumefaciens Lilian Krall, Urs Wiedemann, Gabriele Unsin, Sabine Weiss, Natalie Domke, and Christian Baron Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11405–11410. Published online 2002 August 12. doi: 10.1073/pnas.172390699.PMCID: PMC123269 Rescue of influenza B virus from eight plasmids Erich Hoffmann, Kutubuddin Mahmood, Chin-Fen Yang, Robert G. Webster, Harry B. Greenberg, and George Kemble Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11411–11416. Published online 2002 August 9. doi: 10.1073/pnas.172393399.PMCID: PMC123270 INAUGURAL ARTICLE by a Recently Elected Academy Member: Peptide linkage mapping of the Agrobacterium tumefaciens vir-encoded type IV secretion system reveals protein subassemblies Doyle V. Ward, Olga Draper, John R. Zupan, and Patricia C. Zambryski Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11493–11500. Published online 2002 August 12. doi: 10.1073/pnas.172390299.PMCID: PMC123284 Neurobiology Transitions between dynamical states of differing stability in the human brain Andreas Meyer-Lindenberg, Ulf Ziemann, Göran Hajak, Leonardo Cohen, and Karen Faith Berman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 10948–10953. Published online 2002 July 31. doi: 10.1073/pnas.162114799.PMCID: PMC123190 Glutamatergic activity in the amygdala signals visceral input during taste memory formation María Isabel Miranda, Guillaume Ferreira, Leticia Ramírez-Lugo, and Federico Bermúdez-Rattoni Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11417–11422. Published online 2002 August 7. doi: 10.1073/pnas.182200499.PMCID: PMC123271 Identification of G protein-coupled receptors for Drosophila PRXamide peptides, CCAP, corazonin, and AKH supports a theory of ligand-receptor coevolution Yoonseong Park, Young-Joon Kim, and Michael E. Adams Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11423–11428. Published online 2002 August 12. doi: 10.1073/pnas.162276199.PMCID: PMC123272 Massive cross-modal cortical plasticity and the emergence of a new cortical area in developmentally blind mammals Dianna M. Kahn and Leah Krubitzer Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11429–11434. Published online 2002 August 5. doi: 10.1073/pnas.162342799.PMCID: PMC123273 CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli Michel Barrot, Jocelien D. A. Olivier, Linda I. Perrotti, Ralph J. DiLeone, Olivier Berton, Amelia J. Eisch, Soren Impey, Daniel R. Storm, Rachael L. Neve, Jerry C. Yin, Venetia Zachariou, and Eric J. Nestler Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11435–11440. Published online 2002 August 6. doi: 10.1073/pnas.172091899.PMCID: PMC123274 Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+ Xiaowei Niu and Karl L. Magleby Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11441–11446. Published online 2002 August 2. doi: 10.1073/pnas.172254699.PMCID: PMC123275 Dissociable prefrontal brain systems for attention and emotion Hiroshi Yamasaki, Kevin S. LaBar, and Gregory McCarthy Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11447–11451. Published online 2002 August 12. doi: 10.1073/pnas.182176499.PMCID: PMC123276 Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia Anthony S. Basile, Irina Fedorova, Agustin Zapata, Xiaoguang Liu, Toni Shippenberg, Alokesh Duttaroy, Masahisa Yamada, and Jürgen Wess Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11452–11457. Published online 2002 August 1. doi: 10.1073/pnas.162371899.PMCID: PMC123277 Neural processing of emotional faces requires attention L. Pessoa, M. McKenna, E. Gutierrez, and L. G. Ungerleider Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11458–11463. Published online 2002 August 12. doi: 10.1073/pnas.172403899.PMCID: PMC123278 Newly generated neurons in the amygdala and adjoining cortex of adult primates Patrick J. Bernier, Andréanne Bédard, Jonathan Vinet, Martin Lévesque, and André Parent Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11464–11469. Published online 2002 August 12. doi: 10.1073/pnas.172403999.PMCID: PMC123279 Physiology Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting S. Shenolikar, J. W. Voltz, C. M. Minkoff, J. B. Wade, and E. J. Weinman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11470–11475. Published online 2002 August 8. doi: 10.1073/pnas.162232699.PMCID: PMC123280 Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties Gilles Crambert, Maria Füzesi, Haim Garty, Steven Karlish, and Käthi Geering Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11476–11481. Published online 2002 August 8. doi: 10.1073/pnas.182267299.PMCID: PMC123281 Loss of stearoyl–CoA desaturase-1 function protects mice against adiposity James M. Ntambi, Makoto Miyazaki, Jonathan P. Stoehr, Hong Lan, Christina M. Kendziorski, Brian S. Yandell, Yang Song, Paul Cohen, Jeffrey M. Friedman, and Alan D. Attie Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11482–11486. Published online 2002 August 12. doi: 10.1073/pnas.132384699.PMCID: PMC123282 Plant Biology Integral membrane proteins of the chloroplast envelope: Identification and subcellular localization of new transporters Myriam Ferro, Daniel Salvi, Hélène Rivière-Rolland, Thierry Vermat, Daphné Seigneurin-Berny, Didier Grunwald, Jérôme Garin, Jacques Joyard, and Norbert Rolland Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11487–11492. Published online 2002 August 12. doi: 10.1073/pnas.172390399.PMCID: PMC123283 INAUGURAL ARTICLE by a Recently Elected Academy Member: Peptide linkage mapping of the Agrobacterium tumefaciens vir-encoded type IV secretion system reveals protein subassemblies Doyle V. Ward, Olga Draper, John R. Zupan, and Patricia C. Zambryski Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11493–11500. Published online 2002 August 12. doi: 10.1073/pnas.172390299.PMCID: PMC123284 Cell and chloroplast division requires ARTEMIS Hrvoje Fulgosi, Lars Gerdes, Sabine Westphal, Christel Glockmann, and Jürgen Soll Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11501–11506. Published online 2002 August 8. doi: 10.1073/pnas.172032599.PMCID: PMC123285 RNA helicase-like protein as an early regulator of transcription factors for plant chilling and freezing tolerance Zhizhong Gong, Hojoung Lee, Liming Xiong, André Jagendorf, Becky Stevenson, and Jian-Kang Zhu Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11507–11512. Published online 2002 August 6. doi: 10.1073/pnas.172399299.PMCID: PMC123286 Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: Rapid decay is associated with a group of touch- and specific clock-controlled genes Rodrigo A. Gutiérrez, Rob M. Ewing, J. Michael Cherry, and Pamela J. Green Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11513–11518. Published online 2002 August 7. doi: 10.1073/pnas.152204099.PMCID: PMC123287 The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis Jennifer M. Gagne, Brian P. Downes, Shin-Han Shiu, Adam M. Durski, and Richard D. Vierstra Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11519–11524. Published online 2002 August 8. doi: 10.1073/pnas.162339999.PMCID: PMC123288 Population Biology Signature of balancing selection in Arabidopsis Dacheng Tian, Hitoshi Araki, Eli Stahl, Joy Bergelson, and Martin Kreitman Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11525–11530. Published online 2002 August 9. doi: 10.1073/pnas.172203599.PMCID: PMC123289 Social Sciences Psychology Selective impairment of reasoning about social exchange in a patient with bilateral limbic system damage Valerie E. Stone, Leda Cosmides, John Tooby, Neal Kroll, and Robert T. Knight Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11531–11536. Published online 2002 August 12. doi: 10.1073/pnas.122352699.PMCID: PMC123290 Cross-cultural evidence of cognitive adaptations for social exchange among the Shiwiar of Ecuadorian Amazonia Lawrence S. Sugiyama, John Tooby, and Leda Cosmides Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11537–11542. Published online 2002 August 12. doi: 10.1073/pnas.122352999.PMCID: PMC123291 A model for the simultaneous analysis of reflectance spectra and basis factors of Munsell color samples under D65 illumination in three-dimensional Euclidean space A. Kimball Romney and Tarow Indow Proc Natl Acad Sci U S A. 2002 August 20; 99(17): 11543–11546. Published online 2002 August 2. doi: 10.1073/pnas.162368999.PMCID: PMC123292 |