| | This journal provides immediate access to some articles. Commentaries A cut above: Discovery of an alternative excision repair pathway in bacteria Bennett Van Houten, Jonathan A. Eisen, and Philip C. Hanawalt PMCID: PMC122389 Induction of T cell alertness by bacterial colonization of intestinal epithelium Thomas Spies PMCID: PMC122390 Physical Sciences Applied Physical Sciences A comparison of experimental, theoretical, and numerical simulation Rayleigh–Taylor mixing rates E. George, J. Glimm, X.-L. Li, A. Marchese, and Z.-L. Xu PMCID: PMC122391 Chemistry Chemical amplification with encapsulated reagents Jian Chen, Steffi Körner, Stephen L. Craig, Shirley Lin, Dmitry M. Rudkevich, and Julius Rebek, Jr. PMCID: PMC122392 Asymptotic solution of the cylindrical nonlinear Poisson–Boltzmann equation at low salt concentration: Analytic expressions for surface potential and preferential interaction coefficient Irina A. Shkel, Oleg V. Tsodikov, and M. Thomas Record, Jr. PMCID: PMC122393 Engineering Matching gene activity with physiological functions Wei Huang, Yuh-Pyng Sher, Konan Peck, and Yuan Cheng B. Fung PMCID: PMC122394 Geophysics From the Cover:
Arctic “ozone hole” in a cold volcanic stratosphere A. Tabazadeh, K. Drdla, M. R. Schoeberl, P. Hamill, and O. B. Toon PMCID: PMC122395 Mathematics Dynamics of bacterial phenotype selection in a colonized host G. F. Webb and M. J. Blaser PMCID: PMC122485 Biological Sciences Applied Biological Sciences The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling Yanhong Shi, Michelle Hon, and Ronald M. Evans PMCID: PMC122396 Biochemistry The role of n-3 polyunsaturated fatty acids in brain: Modulation of rat brain gene expression by dietary n-3 fatty acids Klára Kitajka, László G. Puskás, Ágnes Zvara, László Hackler, Jr., Gwendolyn Barceló-Coblijn, Young K. Yeo, and Tibor Farkas PMCID: PMC122397 Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity Pingtao Tang, Tammy P. Cheng, Davide Agnello, Chang-You Wu, Bruce D. Hissong, Wendy T. Watford, Hyun-Jong Ahn, Jerome Galon, Joel Moss, Martha Vaughan, John J. O'Shea, and Massimo Gadina PMCID: PMC122398 tRNA-like recognition of group I introns by a tyrosyl-tRNA synthetase Christopher A. Myers, Birte Kuhla, Stephen Cusack, and Alan M. Lambowitz PMCID: PMC122399 Mechanism for antibody catalysis of the oxidation of water by singlet dioxygen Deepshikha Datta, Nagarajan Vaidehi, Xin Xu, and William A. Goddard, III PMCID: PMC122400 The TRAP/Mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function in vitro Yun Kyoung Kang, Mohamed Guermah, Chao-Xing Yuan, and Robert G. Roeder PMCID: PMC122401 A cofactor approach to copper-dependent catalytic antibodies Kenneth M. Nicholas, Paul Wentworth, Jr., Curtis W. Harwig, Anita D. Wentworth, Asher Shafton, and Kim D. Janda PMCID: PMC122402 Proteome-scale purification of human proteins from bacteria Pascal Braun, Yanhui Hu, Binghua Shen, Allison Halleck, Malvika Koundinya, Ed Harlow, and Joshua LaBaer PMCID: PMC122403 Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+ Daisuke Tsuchiya, Naoki Kunishima, Narutoshi Kamiya, Hisato Jingami, and Kosuke Morikawa PMCID: PMC122404 Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms Arindam Dasgupta, Russell P. Darst, Karla J. Martin, Cynthia A. Afshari, and David T. Auble PMCID: PMC122405 Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands J. F. Riou, L. Guittat, P. Mailliet, A. Laoui, E. Renou, O. Petitgenet, F. Mégnin-Chanet, C. Hélène, and J. L. Mergny PMCID: PMC122406 Transfer RNA-dependent amino acid biosynthesis: An essential route to asparagine formation Bokkee Min, Joanne T. Pelaschier, David E. Graham, Debra Tumbula-Hansen, and Dieter Söll PMCID: PMC122407 Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P Felicia Houser-Scott, Shaohua Xiao, Christopher E. Millikin, Janice M. Zengel, Lasse Lindahl, and David R. Engelke PMCID: PMC122408 Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis David Drew, Dan Sjöstrand, Johan Nilsson, Thomas Urbig, Chen-ni Chin, Jan-Willem de Gier, and Gunnar von Heijne PMCID: PMC122409 Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines Claudio Hetz, María Rosa Bono, Luis Felipe Barros, and Rosalba Lagos PMCID: PMC122410 Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily S. Colette Daubner, Giovanni Gadda, Michael P. Valley, and Paul F. Fitzpatrick PMCID: PMC122411 13C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS) Danhong Lu, Hindrik Mulder, Piyu Zhao, Shawn C. Burgess, Mette V. Jensen, Svetlana Kamzolova, Christopher B. Newgard, and A. Dean Sherry PMCID: PMC122412 Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix Fabrice Allain, Christophe Vanpouille, Mathieu Carpentier, Marie-Christine Slomianny, Sandrine Durieux, and Geneviève Spik PMCID: PMC122413 Activity-dependent isolation of the presenilin– γ-secretase complex reveals nicastrin and a γ substrate William P. Esler, W. Taylor Kimberly, Beth L. Ostaszewski, Wenjuan Ye, Thekla S. Diehl, Dennis J. Selkoe, and Michael S. Wolfe PMCID: PMC122414 Nucleotides and phospholipids compete for binding to the C terminus of KATP channels Gordon G. MacGregor, Ke Dong, Carlos G. Vanoye, LieQi Tang, Gerhard Giebisch, and Steven C. Hebert PMCID: PMC122415 Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding Douglas A. Hattendorf and Susan L. Lindquist PMCID: PMC122416 Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity S. N. Prasanna Murthy, Siiri Iismaa, Gillian Begg, Douglas M. Freymann, Robert M. Graham, and Laszlo Lorand PMCID: PMC122417 Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity Shenping Liu, Richard A. Cerione, and Jon Clardy PMCID: PMC122418 High-quality life extension by the enzyme peptide methionine sulfoxide reductase Hongyu Ruan, Xiang Dong Tang, M.-L. Chen, M. A. Joiner, Guangrong Sun, Nathan Brot, Herbert Weissbach, Stephen H. Heinemann, Linda Iverson, Chun-Fang Wu, and Toshinori Hoshi PMCID: PMC122419 Biophysics Natural β-sheet proteins use negative design to avoid edge-to-edge aggregation Jane S. Richardson and David C. Richardson PMCID: PMC122420 Rationally designed mutations convert de novo amyloid-like fibrils into monomeric β-sheet proteins Weixun Wang and Michael H. Hecht PMCID: PMC122421 Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli Sue A. Roberts, Andrzej Weichsel, Gregor Grass, Keshari Thakali, James T. Hazzard, Gordon Tollin, Christopher Rensing, and William R. Montfort PMCID: PMC122422 Two-photon excitation microscopy of tryptophan-containing proteins M. Lippitz, W. Erker, H. Decker, K. E. van Holde, and T. Basché PMCID: PMC122423 Proton shuttle in green fluorescent protein studied by dynamic simulations Markus A. Lill and Volkhard Helms PMCID: PMC122424 α-Helical stabilization by side chain shielding of backbone hydrogen bonds Angel E. García and Kevin Y. Sanbonmatsu PMCID: PMC122425 Helix formation via conformation diffusion search Cheng-Yen Huang, Zelleka Getahun, Yongjin Zhu, Jason W. Klemke, William F. DeGrado, and Feng Gai PMCID: PMC122426 Network of coupled promoting motions in enzyme catalysis Pratul K. Agarwal, Salomon R. Billeter, P. T. Ravi Rajagopalan, Stephen J. Benkovic, and Sharon Hammes-Schiffer PMCID: PMC122427 From the Cover:
Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c Christian Lange and Carola Hunte PMCID: PMC122428 Crystal structure of an antiparallel DNA fragment with Hoogsteen base pairing Nicola G. A. Abrescia, Andrew Thompson, Tam Huynh-Dinh, and Juan A. Subirana PMCID: PMC122429 Cell Biology Polarized cytokinesis in vacuolate cells of Arabidopsis Sean R. Cutler and David W. Ehrhardt PMCID: PMC122430 Interferon regulatory factor-3 is an in vivo target of DNA-PK Alla Y. Karpova, Maren Trost, John M. Murray, Lewis C. Cantley, and Peter M. Howley PMCID: PMC122431 Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex Oliver J. Rando, Keji Zhao, Paul Janmey, and Gerald R. Crabtree PMCID: PMC122432 Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression Jianyong Shou, Robert Soriano, Simon W. Hayward, Gerald R. Cunha, P. Mickey Williams, and Wei-Qiang Gao PMCID: PMC122433 Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: A DNA microarray analysis Yoon-Jae Song and Mark F. Stinski PMCID: PMC122434 Phosphatidylinositol 4,5-bisphosphate stimulates vesicle formation from liposomes by brain cytosol Masahiro Kinuta, Hiroshi Yamada, Tadashi Abe, Masami Watanabe, Shun-Ai Li, Akihiro Kamitani, Tatsuji Yasuda, Takashi Matsukawa, Hiromi Kumon, and Kohji Takei PMCID: PMC122435 DEC1 is a downstream target of TGF-β with sequence-specific transcriptional repressor activities Leigh Zawel, Jian Yu, Christopher J. Torrance, Sanford Markowitz, Kenneth W. Kinzler, Bert Vogelstein, and Shibin Zhou PMCID: PMC122436 Binding of rainbow trout sperm to egg is mediated by strong carbohydrate-to-carbohydrate interaction between (KDN)GM3 (deaminated neuraminyl ganglioside) and Gg3-like epitope Song Yu, Naoya Kojima, Sen-itiroh Hakomori, Shigeharu Kudo, Sadako Inoue, and Yasuo Inoue PMCID: PMC122437 The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: Implications for a role of BCL6 in the down-regulation of apoptosis Beverly W. Baron, John Anastasi, Michael J. Thirman, Yoichi Furukawa, Scott Fears, David C. Kim, Federico Simone, Mark Birkenbach, Anthony Montag, Annamma Sadhu, Nancy Zeleznik-Le, and Timothy W. McKeithan PMCID: PMC122438 An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels A. John Diamonti, Pamela M. Guy, Caryn Ivanof, Karen Wong, Colleen Sweeney, and Kermit L. Carraway, III PMCID: PMC122439 Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity Darja Schmidt and Stefan Müller PMCID: PMC122440 Developmental Biology Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3 Vinciane Gaussin, Tom Van de Putte, Yuji Mishina, Mark C. Hanks, An Zwijsen, Danny Huylebroeck, Richard R. Behringer, and Michael D. Schneider PMCID: PMC122441 Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis Minjung J. Kim, Robert D. Cardiff, Nishita Desai, Whitney A. Banach-Petrosky, Ramon Parsons, Michael M. Shen, and Cory Abate-Shen PMCID: PMC122442 The mammalian oocyte orchestrates the rate of ovarian follicular development John J. Eppig, Karen Wigglesworth, and Frank L. Pendola PMCID: PMC122443 The interaction between the coactivator dCBP and Modulo, a chromatin-associated factor, affects segmentation and melanotic tumor formation in Drosophila Frédéric Bantignies, Richard H. Goodman, and Sarah M. Smolik PMCID: PMC122444 Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin Thomas Weber, Ulrike Zimmermann, Harald Winter, Andreas Mack, Iris Köpschall, Karin Rohbock, Hans-Peter Zenner, and Marlies Knipper PMCID: PMC122445 Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors Dominique Baas, Claude Legrand, Jacques Samarut, and Frédéric Flamant PMCID: PMC122446 Evolution Inference of functional regions in proteins by quantification of evolutionary constraints Alexander L. Simon, Eric A. Stone, and Arend Sidow PMCID: PMC122447 Wolbachia density and virulence attenuation after transfer into a novel host E. A. McGraw, D. J. Merritt, J. N. Droller, and S. L. O'Neill PMCID: PMC122448 Genetics GATA-1 binding sites mapped in the β-globin locus by using mammalian chIp-chip analysis Christine E. Horak, Milind C. Mahajan, Nicholas M. Luscombe, Mark Gerstein, Sherman M. Weissman, and Michael Snyder PMCID: PMC122449 Genes, pseudogenes, and Alu sequence organization across human chromosomes 21 and 22 Chingfer Chen, Andrew J. Gentles, Jerzy Jurka, and Samuel Karlin PMCID: PMC122450 Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals Sydney Brenner, Byrappa Venkatesh, Wai Ho Yap, Chih-Fong Chou, Alice Tay, Sathivel Ponniah, Yue Wang, and Y. H. Tan PMCID: PMC122451 Genome complexity reduction for SNP genotyping analysis Barbara Jordan, Alain Charest, John F. Dowd, Justin P. Blumenstiel, Ru-fang Yeh, Asiah Osman, David E. Housman, and John E. Landers PMCID: PMC122452 Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function Annemieke de Vries, Elsa R. Flores, Barbara Miranda, Harn-Mei Hsieh, Conny Th. M. van Oostrom, Julien Sage, and Tyler Jacks PMCID: PMC122453 Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or “multiple” colorectal adenomas O. M. Sieber, H. Lamlum, M. D. Crabtree, A. J. Rowan, E. Barclay, L. Lipton, S. Hodgson, H. J. W. Thomas, K. Neale, R. K. S. Phillips, S. M. Farrington, M. G. Dunlop, H. J. Mueller, M. L. Bisgaard, S. Bulow, P. Fidalgo, C. Albuquerque, M. I. Scarano, W. Bodmer, I. P. M. Tomlinson, and K. Heinimann PMCID: PMC122454 The organization of Physcomitrella patens RAD51 genes is unique among eukaryotic organisms Ulrich Markmann-Mulisch, Masood Z. Hadi, Kerstin Koepchen, Juan C. Alonso, Vincenzo E. A. Russo, Jeff Schell, and Bernd Reiss PMCID: PMC122455 Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays Angela Sesto, Manuel Navarro, Frank Burslem, and José L. Jorcano PMCID: PMC122456 Immunology A basolateral sorting motif in the MICA cytoplasmic tail Hiroshi Suemizu, Mirjana Radosavljevic, Minoru Kimura, Sotaro Sadahiro, Shinichi Yoshimura, Seiamak Bahram, and Hidetoshi Inoko PMCID: PMC122457 From the Cover:
Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA Vannary Tieng, Chantal Le Bouguénec, Laurence du Merle, Philippe Bertheau, Pierre Desreumaux, Anne Janin, Dominique Charron, and Antoine Toubert PMCID: PMC122458 Homeostatic T cell proliferation in a T cell-dendritic cell coculture system Qing Ge, Deborah Palliser, Herman N. Eisen, and Jianzhu Chen PMCID: PMC122459 Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments Qing Ge, Hui Hu, Herman N. Eisen, and Jianzhu Chen PMCID: PMC122460 The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines Flavio Leoni, Andrea Zaliani, Giorgio Bertolini, Giulia Porro, Paolo Pagani, Pietro Pozzi, Giancarlo Donà, Gianluca Fossati, Silvano Sozzani, Tania Azam, Philip Bufler, Giamila Fantuzzi, Igor Goncharov, Soo-Hyun Kim, Benjamin J. Pomerantz, Leonid L. Reznikov, Britta Siegmund, Charles A. Dinarello, and Paolo Mascagni PMCID: PMC122461 Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death Laurence E. Cheng, Claes Öhlén, Brad H. Nelson, and Philip D. Greenberg PMCID: PMC122462 Identification of a germ-line pro-B cell subset that distinguishes the fetal/neonatal from the adult B cell development pathway Li-Sheng Lu, James Tung, Nicole Baumgarth, Ometa Herman, Michael Gleimer, Leonard A. Herzenberg, and Leonore A. Herzenberg PMCID: PMC122463 Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice Arthur A. Hurwitz, Timothy J. Sullivan, Raymond A. Sobel, and James P. Allison PMCID: PMC122464 Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity Didi Matza, Frida Lantner, Yoel Bogoch, Liat Flaishon, Rami Hershkoviz, and Idit Shachar PMCID: PMC122465 Medical Sciences Matching gene activity with physiological functions Wei Huang, Yuh-Pyng Sher, Konan Peck, and Yuan Cheng B. Fung PMCID: PMC122394 Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells Yang D. Teng, Erin B. Lavik, Xianlu Qu, Kook I. Park, Jitka Ourednik, David Zurakowski, Robert Langer, and Evan Y. Snyder PMCID: PMC122466 Ex vivo cell labeling with 64Cu–pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography Nora Adonai, Khoi N. Nguyen, Joseph Walsh, M. Iyer, Tatsushi Toyokuni, Michael E. Phelps, Timothy McCarthy, Deborah W. McCarthy, and Sanjiv Sam Gambhir PMCID: PMC122467 From the Cover:
West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacy Alexander G. Pletnev, Robert Putnak, Jim Speicher, Eric J. Wagar, and David W. Vaughn PMCID: PMC122468 Identification in traditional herbal medications and confirmation by synthesis of factors that inhibit cholera toxin-induced fluid accumulation Hiroshi Oi, Daisuke Matsuura, Masami Miyake, Masamiti Ueno, Izumi Takai, Takeshi Yamamoto, Masayoshi Kubo, Joel Moss, and Masatoshi Noda PMCID: PMC122469 Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm Aslihan Turhan, Linnea A. Weiss, Narla Mohandas, Barry S. Coller, and Paul S. Frenette PMCID: PMC122470 Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase Han-Mo Koo, Matt VanBrocklin, Mary Jane McWilliams, Stephan H. Leppla, Nicholas S. Duesbery, and George F. Vande Woude PMCID: PMC122471 PATE, a gene expressed in prostate cancer, normal prostate, and testis, identified by a functional genomic approach Tapan K. Bera, Rangan Maitra, Carlo Iavarone, Giuliana Salvatore, Vasantha Kumar, James J. Vincent, B. K. Sathyanarayana, Paul Duray, B. K. Lee, and Ira Pastan PMCID: PMC122472 A prototypic platelet septin and its participation in secretion Judith Dent, Kazunobu Kato, Xiao-Rong Peng, Constantino Martinez, Marco Cattaneo, Christel Poujol, Paquita Nurden, Alan Nurden, William S. Trimble, and Jerry Ware PMCID: PMC122473 Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia Yanming Zhang, Pamela Strissel, Reiner Strick, Jianjun Chen, Giuseppina Nucifora, Michelle M. Le Beau, Richard A. Larson, and Janet D. Rowley PMCID: PMC122474 Prevalence of somatic alterations in the colorectal cancer cell genome Tian-Li Wang, Carlo Rago, Natalie Silliman, Janine Ptak, Sanford Markowitz, James K. V. Willson, Giovanni Parmigiani, Kenneth W. Kinzler, Bert Vogelstein, and Victor E. Velculescu PMCID: PMC122475 Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome Patrizia Farci, Rita Strazzera, Harvey J. Alter, Stefania Farci, Daniela Degioannis, Alessandra Coiana, Giovanna Peddis, Francesco Usai, Giancarlo Serra, Luchino Chessa, Giacomo Diaz, Angelo Balestrieri, and Robert H. Purcell PMCID: PMC122476 Mortality in 7B2 null mice can be rescued by adrenalectomy: Involvement of dopamine in ACTH hypersecretion V. Laurent, A. Kimble, B. Peng, P. Zhu, J. E. Pintar, D. F. Steiner, and I. Lindberg PMCID: PMC122477 CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo Lynda S. Ostedgaard, Joseph Zabner, Daniel W. Vermeer, Tatiana Rokhlina, Philip H. Karp, Arlene A. Stecenko, Christoph Randak, and Michael J. Welsh PMCID: PMC122478 NQO1 stabilizes p53 through a distinct pathway Gad Asher, Joseph Lotem, Rachel Kama, Leo Sachs, and Yosef Shaul PMCID: PMC122479 Noninvasive quantitative imaging of protein–protein interactions in living subjects P. Ray, H. Pimenta, R. Paulmurugan, F. Berger, M. E. Phelps, M. Iyer, and S. S. Gambhir PMCID: PMC122480 Quantitative in vivo assessment of lung microstructure at the alveolar level with hyperpolarized 3He diffusion MRI Dmitriy A. Yablonskiy, Alexander L. Sukstanskii, Jason C. Leawoods, David S. Gierada, G. Larry Bretthorst, Stephen S. Lefrak, Joel D. Cooper, and Mark S. Conradi PMCID: PMC122481 Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis Abdul Waheed, Jeffrey H. Grubb, Xiao Yan Zhou, Shunji Tomatsu, Robert E. Fleming, Mark E. Costaldi, Robert S. Britton, Bruce R. Bacon, and William S. Sly PMCID: PMC122482 Drug selection with paclitaxel restores expression of linked IL-2 receptor γ-chain and multidrug resistance (MDR1) transgenes in canine bone marrow Thomas Licht, Mark Haskins, Paula Henthorn, Sandra E. Kleiman, David M. Bodine, Todd Whitwam, Jennifer M. Puck, Michael M. Gottesman, and John R. Melniczek PMCID: PMC122483 Microbiology Quorum-sensing regulators control virulence gene expression in Vibrio cholerae Jun Zhu, Melissa B. Miller, Russell E. Vance, Michelle Dziejman, Bonnie L. Bassler, and John J. Mekalanos PMCID: PMC122484 Dynamics of bacterial phenotype selection in a colonized host G. F. Webb and M. J. Blaser PMCID: PMC122485 Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein Julie A. Heider, Wade A. Bresnahan, and Thomas E. Shenk PMCID: PMC122486 Mycobacterium tuberculosis WhiB3 interacts with RpoV to affect host survival but is dispensable for in vivo growth Adrie J. C. Steyn, Desmond M. Collins, Mary K. Hondalus, William R. Jacobs, Jr., R. Pamela Kawakami, and Barry R. Bloom PMCID: PMC122487 Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes Georg Kochs, Christian Janzen, Heinz Hohenberg, and Otto Haller PMCID: PMC122488 The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum Stefan Pukatzki, Richard H. Kessin, and John J. Mekalanos PMCID: PMC122489 Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm Stephanie C. Tucker and Arturo Casadevall PMCID: PMC122490 Rapid assembly dynamics of the Escherichia coli FtsZ-ring demonstrated by fluorescence recovery after photobleaching Jesse Stricker, Paul Maddox, E. D. Salmon, and Harold P. Erickson PMCID: PMC122491 Neurobiology Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness Daniel H. Geschwind, Bruce L. Miller, Charles DeCarli, and Dorit Carmelli PMCID: PMC122492 Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac) Per Svenningsson, Eleni T. Tzavara, Jeffrey M. Witkin, Allen A. Fienberg, George G. Nomikos, and Paul Greengard PMCID: PMC122493 DARPP-32 mediates serotonergic neurotransmission in the forebrain Per Svenningsson, Eleni T. Tzavara, Feng Liu, Allen A. Fienberg, George G. Nomikos, and Paul Greengard PMCID: PMC122494 Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells Hill-Aina Steffenach, Robert S. Sloviter, Edvard I. Moser, and May-Britt Moser PMCID: PMC122495 Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON Samie R. Jaffrey, Fabio Benfenati, Adele M. Snowman, Andrew J. Czernik, and Solomon H. Snyder PMCID: PMC122496 Order-sensitive plasticity in adult primary auditory cortex Michael P. Kilgard and Michael M. Merzenich PMCID: PMC122497 Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites Nicolas Le Novère, Thomas Grutter, and Jean-Pierre Changeux PMCID: PMC122498 Experimentally based model of a complex between a snake toxin and the α7 nicotinic receptor Carole Fruchart-Gaillard, Bernard Gilquin, Stéphanie Antil-Delbeke, Nicolas Le Novère, Toru Tamiya, Pierre-Jean Corringer, Jean-Pierre Changeux, André Ménez, and Denis Servent PMCID: PMC122499 Selective imaging of presynaptic activity in the mouse olfactory bulb shows concentration and structure dependence of odor responses in identified glomeruli Hans U. Fried, Stefan H. Fuss, and Sigrun I. Korsching PMCID: PMC122500 Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophrenia Tyrone D. Cannon, Paul M. Thompson, Theo G. M. van Erp, Arthur W. Toga, Veli-Pekka Poutanen, Matti Huttunen, Jouko Lonnqvist, Carl-Gustav Standerskjold-Nordenstam, Katherine L. Narr, Mohammad Khaledy, Chris I. Zoumalan, Rajneesh Dail, and Jaakko Kaprio PMCID: PMC122501 Neuronal activity-dependent membrane traffic at the neuromuscular junction Francisco Javier Miana-Mena, Sylvie Roux, Jean-Claude Benichou, Rosario Osta, and Philippe Brûlet PMCID: PMC122502 Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism Donald J. Marsh, Drew T. Weingarth, Dawn E. Novi, Howard Y. Chen, Myrna E. Trumbauer, Airu S. Chen, Xiao-Ming Guan, Michael M. Jiang, Yue Feng, Ramon E. Camacho, Zhu Shen, Easter G. Frazier, Hong Yu, Joseph M. Metzger, Stephanie J. Kuca, Lauren P. Shearman, Shobhna Gopal-Truter, Douglas J. MacNeil, Alison M. Strack, D. Euan MacIntyre, Lex H. T. Van der Ploeg, and Su Qian PMCID: PMC122503 Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury Brian K. Kwon, Jie Liu, Corrie Messerer, Nao R. Kobayashi, John McGraw, Loren Oschipok, and Wolfram Tetzlaff PMCID: PMC122504 Visualization of functionally activated circuitry in the brain Yvette Wilson, Nupur Nag, Pamela Davern, Brian J. Oldfield, Michael J. McKinley, Ursula Greferath, and Mark Murphy PMCID: PMC122505 Thyroid hormone activates oligodendrocyte precursors and increases a myelin-forming protein and NGF content in the spinal cord during experimental allergic encephalomyelitis Laura Calza, Mercedes Fernandez, Alessandro Giuliani, Luigi Aloe, and Luciana Giardino PMCID: PMC122506 Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans Richard Nass, David H. Hall, David M. Miller, III, and Randy D. Blakely PMCID: PMC122507 Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia Hyo Chol Ha, Lynda D. Hester, and Solomon H. Snyder PMCID: PMC122508 Molecular basis of R-type calcium channels in central amygdala neurons of the mouse Seung-Chan Lee, Sukwoo Choi, Taehoon Lee, Hyung-Lae Kim, Hemin Chin, and Hee-Sup Shin PMCID: PMC122509 Pharmacology Nitric oxide down-regulates brain-derived neurotrophic factor secretion in cultured hippocampal neurons Marco Canossa, Emanuele Giordano, Silvia Cappello, Carlo Guarnieri, and Sergio Ferri PMCID: PMC122510 Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum Toshiaki Kume, Naoki Asai, Hiroyuki Nishikawa, Nariyasu Mano, Taro Terauchi, Ryota Taguchi, Hisashi Shirakawa, Fumitaka Osakada, Hiroki Mori, Naoki Asakawa, Masahiro Yonaga, Yukio Nishizawa, Hachiro Sugimoto, Shun Shimohama, Hiroshi Katsuki, Shuji Kaneko, and Akinori Akaike PMCID: PMC122511 Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells Ramesh C. Patel, Ujendra Kumar, Don C. Lamb, John S. Eid, Magalie Rocheville, Michael Grant, Aruna Rani, Theodore Hazlett, Shutish C. Patel, Enrico Gratton, and Yogesh C. Patel PMCID: PMC122512 Physiology Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotropin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells Eleni Aggelidou, Edward W. Hillhouse, and Dimitris K. Grammatopoulos PMCID: PMC122513 Sexually dimorphic expression of estrogen receptor β in the anteroventral periventricular nucleus of the rat preoptic area: Implication in luteinizing hormone surge Chitose Orikasa, Yasuhiko Kondo, Shinji Hayashi, Bruce S. McEwen, and Yasuo Sakuma PMCID: PMC122514 Protection of cardiac mitochondria by diazoxide and protein kinase C: Implications for ischemic preconditioning Paavo Korge, Henry M. Honda, and James N. Weiss PMCID: PMC122515 Revised estimates of human cochlear tuning from otoacoustic and behavioral measurements Christopher A. Shera, John J. Guinan, Jr., and Andrew J. Oxenham PMCID: PMC122516 Heterologous regulation of trafficking and signaling of G protein-coupled receptors: β-Arrestin-dependent interactions between neurokinin receptors Fabien Schmidlin, Olivier Déry, Nigel W. Bunnett, and Eileen F. Grady PMCID: PMC122517 Plant Biology From the Cover:
Light modulation of Rubisco in Arabidopsis requires a capacity for redox regulation of the larger Rubisco activase isoform Ning Zhang, Russell P. Kallis, Robert G. Ewy, and Archie R. Portis, Jr. PMCID: PMC122518 A stilbene synthase from Japanese red pine (Pinus densiflora): Implications for phytoalexin accumulation and down-regulation of flavonoid biosynthesis Atsushi Kodan, Hiroyuki Kuroda, and Fukumi Sakai PMCID: PMC122519 The mur2 mutant of Arabidopsis thaliana lacks fucosylated xyloglucan because of a lesion in fucosyltransferase AtFUT1 Gary F. Vanzin, Michael Madson, Nicholas C. Carpita, Natasha V. Raikhel, Kenneth Keegstra, and Wolf-Dieter Reiter PMCID: PMC122520 Psychology Revised estimates of human cochlear tuning from otoacoustic and behavioral measurements Christopher A. Shera, John J. Guinan, Jr., and Andrew J. Oxenham PMCID: PMC122516 Neural mechanisms of planning: A computational analysis using event-related fMRI Jon M. Fincham, Cameron S. Carter, Vincent van Veen, V. Andrew Stenger, and John R. Anderson PMCID: PMC122521 Social Sciences Economic Sciences Framing effects and risky decisions in starlings Barnaby Marsh and Alex Kacelnik PMCID: PMC122522 Corrections Proc Natl Acad Sci U S A. 2002 March 5; 99(5): 3356. Published online 2002 February 19. doi: 10.1073/pnas.062024499.PMCID: PMC122387 Corrects: J. Jelenska, et al. Subcellular localization of acetyl-CoA carboxylase in the
apicomplexan parasite Toxoplasma gondii. Proc Natl Acad Sci U S A. 2001 February 27; 98(5): 2723–2728. Proc Natl Acad Sci U S A. 2002 March 5; 99(5): 3356. doi: 10.1073/pnas.062024099.PMCID: PMC122388 Corrects: Sen-itiroh Hakomori. INAUGURAL ARTICLE by a Recently Elected Academy Member: The glycosynapse. Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 225–232. |
