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Volume 99(1);  January 8, 2002
Commentaries
Brucella melitensis: A nasty bug with hidden credentials for virulence
Edgardo Moreno and Ignacio Moriyón
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 1–3. doi: 10.1073/pnas.022622699.
PMCID: PMC117501
Structured intermittent treatment for HIV disease: Necessary concession or premature compromise?
Diane V. Havlir
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 4–6. doi: 10.1073/pnas.022629399.
PMCID: PMC117502
Bacterial chemotaxis and the question of gain
Dennis Bray
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 7–9. doi: 10.1073/pnas.022641699.
PMCID: PMC117503
In our genes
Henry Harpending and Gregory Cochran
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 10–12. doi: 10.1073/pnas.012612799.
PMCID: PMC117504
Physical Sciences
Chemistry
Femtosecond dynamics of rubredoxin: Tryptophan solvation and resonance energy transfer in the protein
Dongping Zhong, Samir Kumar Pal, Deqiang Zhang, Sunney I. Chan, and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 13–18. Published online 2001 December 18. doi: 10.1073/pnas.012582399.
PMCID: PMC117505
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
Kristi L. Kiick, Eliana Saxon, David A. Tirrell, and Carolyn R. Bertozzi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 19–24. Published online 2001 December 18. doi: 10.1073/pnas.012583299.
PMCID: PMC117506
Geophysics
High-pressure transformations in xenon hydrates
Chrystèle Sanloup, Ho-kwang Mao, and Russell J. Hemley
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 25–28. Published online 2001 December 26. doi: 10.1073/pnas.221602698.
PMCID: PMC117507
Physics
Generation of ultra-intense single-cycle laser pulses by using photon deceleration
F. S. Tsung, C. Ren, L. O. Silva, W. B. Mori, and T. Katsouleas
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 29–32. Published online 2001 December 18. doi: 10.1073/pnas.262543899.
PMCID: PMC117508
A closer look at the elementary fermions
Maurice Goldhaber
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 33–36. Published online 2002 January 2. doi: 10.1073/pnas.221582298.
PMCID: PMC117509
Biological Sciences
Agricultural Sciences
Insect NMDA receptors mediate juvenile hormone biosynthesis
Ann-Shyn Chiang, Wei-Yong Lin, Hsin-Ping Liu, Maciej A. Pszczolkowski, Tsai-Feng Fu, Shu-Ling Chiu, and Glenn L. Holbrook
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 37–42. Published online 2002 January 2. doi: 10.1073/pnas.012318899.
PMCID: PMC117510
Anthropology
High levels of Y-chromosome nucleotide diversity in the genus Pan
Anne C. Stone, Robert C. Griffiths, Stephen L. Zegura, and Michael F. Hammer
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 43–48. Published online 2001 December 26. doi: 10.1073/pnas.012364999.
PMCID: PMC117511
Applied Biological Sciences
Biosensors from conjugated polyelectrolyte complexes
Deli Wang, Xiong Gong, Peter S. Heeger, Frauke Rininsland, Guillermo C. Bazan, and Alan J. Heeger
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 49–53. Published online 2001 December 26. doi: 10.1073/pnas.012581399.
PMCID: PMC117512
Efficient bacterial transcription of DNA nanocircle vectors with optimized single-stranded promoters
Tatsuo Ohmichi, Angèle Maki, and Eric T. Kool
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 54–59. Published online 2001 December 18. doi: 10.1073/pnas.012589099.
PMCID: PMC117513
Biochemistry
Integration of Shaker-type K+ channel, KAT1, into the endoplasmic reticulum membrane: Synergistic insertion of voltage-sensing segments, S3–S4, and independent insertion of pore-forming segments, S5–P–S6
Yoko Sato, Masao Sakaguchi, Shinobu Goshima, Tatsunosuke Nakamura, and Nobuyuki Uozumi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 60–65. Published online 2001 December 26. doi: 10.1073/pnas.012399799.
PMCID: PMC117514
Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides
Teruhiko Shimokawa, Monica V. Kumar, and M. Daniel Lane
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 66–71. Published online 2001 December 26. doi: 10.1073/pnas.012606199.
PMCID: PMC117515
DNA sequence recognition in the minor groove by crosslinked polyamides: The effect of N-terminal head group and linker length on binding affinity and specificity
C. Caroline O'Hare, Darcy Mack, Manju Tandon, Sanjay K. Sharma, J. William Lown, Mary L. Kopka, Richard E. Dickerson, and John A. Hartley
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 72–77. Published online 2001 December 26. doi: 10.1073/pnas.012588799.
PMCID: PMC117516
The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase
Maria A. Schumacher, Caleb J. Bashor, Minsun Hong Song, Kanao Otsu, Shuren Zhu, Ronald J. Parry, Buddy Ullman, and Richard G. Brennan
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 78–83. Published online 2002 January 2. doi: 10.1073/pnas.012399599.
PMCID: PMC117517
Identification of a potent antidiuretic factor acting on beetle Malpighian tubules
Richard A. Eigenheer, Susan W. Nicolson, Kathleen M. Schegg, J. Joe Hull, and David A. Schooley
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 84–89. Published online 2001 December 26. doi: 10.1073/pnas.012436199.
PMCID: PMC117518
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
Peter L. Nagy, Joachim Griesenbeck, Roger D. Kornberg, and Michael L. Cleary
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 90–94. Published online 2001 December 18. doi: 10.1073/pnas.221596698.
PMCID: PMC117519
From the Cover:
Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo
M. D. Kaeser and R. D. Iggo
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 95–100. Published online 2001 December 26. doi: 10.1073/pnas.012283399.
PMCID: PMC117520
The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation
Gwendolyn M. Wilmes and Stephen P. Bell
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 101–106. Published online 2001 December 26. doi: 10.1073/pnas.012578499.
PMCID: PMC117521
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans
Subrata Adak, Alexandrine M. Bilwes, Koustubh Panda, David Hosfield, Kulwant S. Aulak, John F. McDonald, John A. Tainer, Elizabeth D. Getzoff, Brian R. Crane, and Dennis J. Stuehr
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 107–112. Published online 2001 December 26. doi: 10.1073/pnas.012470099.
PMCID: PMC117522
Regulatory DNA required for vnd/NK-2 homeobox gene expression pattern in neuroblasts
Xiaoping Shao, Keita Koizumi, Neil Nosworthy, Dong-Ping Tan, Ward Odenwald, and Marshall Nirenberg
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 113–117. Published online 2001 December 18. doi: 10.1073/pnas.012584599.
PMCID: PMC117523
A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2
Stefan Krauss, Chen-Yu Zhang, and Bradford B. Lowell
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 118–122. Published online 2001 December 26. doi: 10.1073/pnas.012410699.
PMCID: PMC117524
Receptor sensitivity in bacterial chemotaxis
Victor Sourjik and Howard C. Berg
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 123–127. Published online 2001 December 11. doi: 10.1073/pnas.011589998.
PMCID: PMC117525
Recruitment of intron-encoded and co-opted proteins in splicing of the bI3 group I intron RNA
Gurminder S. Bassi, Daniela M. de Oliveira, Malcolm F. White, and Kevin M. Weeks
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 128–133. Published online 2002 January 2. doi: 10.1073/pnas.012579299.
PMCID: PMC117526
Effect of HIV integrase inhibitors on the RAG1/2 recombinase
Meni Melek, Jessica M. Jones, Mary H. O'Dea, Godwin Pais, Terrence R. Burke, Jr., Yves Pommier, Nouri Neamati, and Martin Gellert
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 134–137. Published online 2001 December 26. doi: 10.1073/pnas.012610699.
PMCID: PMC117527
Quaternary structure of human fatty acid synthase by electron cryomicroscopy
Jacob Brink, Steven J. Ludtke, Chao-Yuh Yang, Zei-Wei Gu, Salih J. Wakil, and Wah Chiu
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 138–143. Published online 2001 December 26. doi: 10.1073/pnas.012589499.
PMCID: PMC117528
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites
Peter D. Senter, Yousef Al-Abed, Christine N. Metz, Fabio Benigni, Robert A. Mitchell, J. Chesney, Jianlin Han, Carlos G. Gartner, Sidney D. Nelson, George J. Todaro, and Richard Bucala
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 144–149. Published online 2002 January 2. doi: 10.1073/pnas.011569399.
PMCID: PMC117529
Biophysics
Femtosecond dynamics of rubredoxin: Tryptophan solvation and resonance energy transfer in the protein
Dongping Zhong, Samir Kumar Pal, Deqiang Zhang, Sunney I. Chan, and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 13–18. Published online 2001 December 18. doi: 10.1073/pnas.012582399.
PMCID: PMC117505
Structure determination of micelle-like intermediates in amyloid β-protein fibril assembly by using small angle neutron scattering
Winnie Yong, Aleksey Lomakin, Marina D. Kirkitadze, David B. Teplow, Sow-Hsin Chen, and George B. Benedek
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 150–154. Published online 2001 December 26. doi: 10.1073/pnas.012584899.
PMCID: PMC117530
Exploring the folding landscape of a structured RNA
Rick Russell, Xiaowei Zhuang, Hazen P. Babcock, Ian S. Millett, Sebastian Doniach, Steven Chu, and Daniel Herschlag
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 155–160. Published online 2001 December 26. doi: 10.1073/pnas.221593598.
PMCID: PMC117531
Cell Biology
From the Cover:
Dynamin at actin tails
Eunkyung Lee and Pietro De Camilli
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 161–166. doi: 10.1073/pnas.012607799.
PMCID: PMC117532
From the Cover:
The large GTPase dynamin regulates actin comet formation and movement in living cells
James D. Orth, E. W. Krueger, H. Cao, and Mark A. McNiven
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 167–172. doi: 10.1073/pnas.012607899.
PMCID: PMC117533
A human aminoacyl-tRNA synthetase as a regulator of angiogenesis
Keisuke Wakasugi, Bonnie M. Slike, John Hood, Atsushi Otani, Karla L. Ewalt, Martin Friedlander, David A. Cheresh, and Paul Schimmel
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 173–177. Published online 2002 January 2. doi: 10.1073/pnas.012602099.
PMCID: PMC117534
A fragment of human TrpRS as a potent antagonist of ocular angiogenesis
Atsushi Otani, Bonnie M. Slike, Michael I. Dorrell, John Hood, Karen Kinder, Karla L. Ewalt, David Cheresh, Paul Schimmel, and Martin Friedlander
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 178–183. Published online 2002 January 2. doi: 10.1073/pnas.012601899.
PMCID: PMC117535
Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase
Natalia I. Dmitrieva, Dmitry V. Bulavin, Albert J. Fornace, Jr., and Maurice B. Burg
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 184–189. Published online 2001 December 26. doi: 10.1073/pnas.231623498.
PMCID: PMC117536
Regulation of starvation- and virus-induced autophagy by the eIF2α kinase signaling pathway
Zsolt Tallóczy, Wenxia Jiang, Herbert W. Virgin, IV, David A. Leib, Donalyn Scheuner, Randal J. Kaufman, Eeva-Liisa Eskelinen, and Beth Levine
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 190–195. Published online 2001 December 26. doi: 10.1073/pnas.012485299.
PMCID: PMC117537
Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs
Hippokratis Kiaris, Andrew V. Schally, Rebeca Busto, Gabor Halmos, Spyros Artavanis–Tsakonas, and Jozsef L. Varga
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 196–200. Published online 2002 January 2. doi: 10.1073/pnas.012590999.
PMCID: PMC117538
Translocation of Cockayne syndrome group A protein to the nuclear matrix: Possible relevance to transcription-coupled DNA repair
Shinya Kamiuchi, Masafumi Saijo, Elisabetta Citterio, Martijn de Jager, Jan H. J. Hoeijmakers, and Kiyoji Tanaka
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 201–206. doi: 10.1073/pnas.012473199.
PMCID: PMC117539
CCAAT/enhancer binding protein-β is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling
Songyun Zhu, Kyungsil Yoon, Esta Sterneck, Peter F. Johnson, and Robert C. Smart
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 207–212. Published online 2001 December 26. doi: 10.1073/pnas.012437299.
PMCID: PMC117540
Molecular immunolabeling with recombinant single-chain variable fragment (scFv) antibodies designed with metal-binding domains
Marek Malecki, Annie Hsu, Lynn Truong, and Sylvia Sanchez
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 213–218. Published online 2001 December 26. doi: 10.1073/pnas.261567298.
PMCID: PMC117541
Activation of β-catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias
Keiko Miyoshi, Jonathan M. Shillingford, Fabienne Le Provost, Fotini Gounari, Roderick Bronson, Harald von Boehmer, Makoto M. Taketo, Robert D. Cardiff, Lothar Hennighausen, and Khashayarsha Khazaie
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 219–224. Published online 2002 January 2. doi: 10.1073/pnas.012414099.
PMCID: PMC117542
The glycosynapse
Sen-itiroh Hakomori
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 225–232. Published online 2002 January 2. doi: 10.1073/pnas.012540899.
PMCID: PMC117543
UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization
Charles L. Limoli, Erich Giedzinski, William M. Bonner, and James E. Cleaver
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 233–238. Published online 2001 December 26. doi: 10.1073/pnas.231611798.
PMCID: PMC117544
Mullerian-inhibiting substance regulates NF–κB signaling in the prostate in vitro and in vivo
Dorry L. Segev, Yasunori Hoshiya, Makiko Hoshiya, Trinh T. Tran, Jennifer L. Carey, Antonia E. Stephen, David T. MacLaughlin, Patricia K. Donahoe, and Shyamala Maheswaran
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 239–244. Published online 2002 January 2. doi: 10.1073/pnas.221599298.
PMCID: PMC117545
Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage
El Bachir Affar, Rashmi G. Shah, Annie-Karine Dallaire, Vincent Castonguay, and Girish M. Shah
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 245–250. Published online 2001 December 26. doi: 10.1073/pnas.012460399.
PMCID: PMC117546
Developmental Biology
A role for biliverdin IXα in dorsal axis development of Xenopus laevis embryos
Kenneth H. Falchuk, Jennifer M. Contin, T. Scott Dziedzic, Zhongling Feng, Thayer C. French, Gregory J. Heffron, and Marcelo Montorzi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 251–256. doi: 10.1073/pnas.012616099.
PMCID: PMC117547
EDEN-dependent translational repression of maternal mRNAs is conserved between Xenopus and Drosophila
Nader Ezzeddine, Luc Paillard, Michèle Capri, Dominique Maniey, Thérèse Bassez, Ounissa Aït-Ahmed, and H. Beverley Osborne
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 257–262. Published online 2001 December 26. doi: 10.1073/pnas.012555499.
PMCID: PMC117548
Ecology
Disappearance of insectivorous birds from tropical forest fragments
Çagan H. Şekercioglu, Paul R. Ehrlich, Gretchen C. Daily, Deniz Aygen, David Goehring, and Randi F. Sandí
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 263–267. doi: 10.1073/pnas.012616199.
PMCID: PMC117549
Evolution
Sequence evolution and copy number of Ty1-copia retrotransposons in diverse plant genomes
Aura Navarro-Quezada and Daniel J. Schoen
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 268–273. Published online 2001 December 18. doi: 10.1073/pnas.012422299.
PMCID: PMC117550
A single Hox3 gene with composite bicoid and zerknüllt expression characteristics in non-Cyclorrhaphan flies
Michael Stauber, Alexander Prell, and Urs Schmidt-Ott
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 274–279. Published online 2002 January 2. doi: 10.1073/pnas.012292899.
PMCID: PMC117551
Mariner-like transposases are widespread and diverse in flowering plants
Cédric Feschotte and Susan R. Wessler
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 280–285. Published online 2001 December 26. doi: 10.1073/pnas.022626699.
PMCID: PMC117552
Evolution of sociality in a primitively eusocial lineage of bees
Bryan N. Danforth
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 286–290. Published online 2001 December 26. doi: 10.1073/pnas.012387999.
PMCID: PMC117553
Sequence analysis of mouse vomeronasal receptor gene clusters reveals common promoter motifs and a history of recent expansion
Robert P. Lane, Tyler Cutforth, Richard Axel, Leroy Hood, and Barbara J. Trask
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 291–296. Published online 2001 December 18. doi: 10.1073/pnas.012608399.
PMCID: PMC117554
Phylogenetic relationships among domesticated and wild species of Cucurbita (Cucurbitaceae) inferred from a mitochondrial gene: Implications for crop plant evolution and areas of origin
Oris I. Sanjur, Dolores R. Piperno, Thomas C. Andres, and Linda Wessel-Beaver
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 535–540. doi: 10.1073/pnas.012577299.
PMCID: PMC117595
Genetics
Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene
Sumitaka Hasegawa, Tomoyuki Sato, Hiroshi Akazawa, Hitoshi Okada, Akiteru Maeno, Masaki Ito, Yoshinobu Sugitani, Hiroyuki Shibata, Jun-ichi Miyazaki, Motoya Katsuki, Yasutaka Yamauchi, Ken-ichi Yamamura, Shigeru Katamine, and Tetsuo Noda
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 297–302. Published online 2001 December 26. doi: 10.1073/pnas.012264999.
PMCID: PMC117555
Effects of peroxisome proliferator-activated receptor δ on placentation, adiposity, and colorectal cancer
Yaacov Barak, Debbie Liao, Weimin He, Estelita S. Ong, Michael C. Nelson, Jerrold M. Olefsky, Richard Boland, and Ronald M. Evans
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 303–308. Published online 2001 December 26. doi: 10.1073/pnas.012610299.
PMCID: PMC117556
From the Cover:
Evidence of positive selection acting at the human dopamine receptor D4 gene locus
Yuan-Chun Ding, Han-Chang Chi, Deborah L. Grady, Atsuyuki Morishima, Judith R. Kidd, Kenneth K. Kidd, Pamela Flodman, M. Anne Spence, Sabrina Schuck, James M. Swanson, Ya-Ping Zhang, and Robert K. Moyzis
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 309–314. Published online 2001 December 26. doi: 10.1073/pnas.012464099.
PMCID: PMC117557
Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE)
Dror Sharon, Seth Blackshaw, Constance L. Cepko, and Thaddeus P. Dryja
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 315–320. Published online 2001 December 26. doi: 10.1073/pnas.012582799.
PMCID: PMC117558
Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p
Jochen Hampe, Henning Frenzel, Muddassar M. Mirza, Peter J. P. Croucher, Andrew Cuthbert, Silvia Mascheretti, Klaus Huse, Matthias Platzer, Stephen Bridger, Birgit Meyer, Peter Nürnberg, Pieter Stokkers, Michael Krawczak, Christopher G. Mathew, Mark Curran, and Stefan Schreiber
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 321–326. Published online 2001 December 18. doi: 10.1073/pnas.261567999.
PMCID: PMC117559
Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome
John M. Greally
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 327–332. Published online 2001 December 26. doi: 10.1073/pnas.012539199.
PMCID: PMC117560
Amino acid runs in eukaryotic proteomes and disease associations
Samuel Karlin, Luciano Brocchieri, Aviv Bergman, Jan Mrázek, and Andrew J. Gentles
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 333–338. doi: 10.1073/pnas.012608599.
PMCID: PMC117561
Immunology
A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum
Anthony W. Stowers, Li-how Chen, Yanling Zhang, Michael C. Kennedy, Lanling Zou, Lynn Lambert, Timothy J. Rice, David C. Kaslow, Allan Saul, Carole A. Long, Harry Meade, and Louis H. Miller
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 339–344. Published online 2001 December 18. doi: 10.1073/pnas.012590199.
PMCID: PMC117562
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response
Robert A. Mitchell, Hong Liao, Jason Chesney, Gunter Fingerle-Rowson, John Baugh, John David, and Richard Bucala
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 345–350. Published online 2001 December 26. doi: 10.1073/pnas.012511599.
PMCID: PMC117563
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
Ralph Marvin Steinman and Michel C. Nussenzweig
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 351–358. Published online 2002 January 2. doi: 10.1073/pnas.231606698.
PMCID: PMC117564
Phosphoinositide 3-kinase and Bruton's tyrosine kinase regulate overlapping sets of genes in B lymphocytes
David A. Fruman, Gregory Z. Ferl, Sam S. An, Amber C. Donahue, Anne B. Satterthwaite, and Owen N. Witte
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 359–364. Published online 2001 December 26. doi: 10.1073/pnas.012605099.
PMCID: PMC117565
Medical Sciences
Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis
Yoshinori Ino, Masahiro Gotoh, Michiie Sakamoto, Kiyomi Tsukagoshi, and Setsuo Hirohashi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 365–370. Published online 2001 December 26. doi: 10.1073/pnas.012425299.
PMCID: PMC117566
Tumor attenuation by combined heparan sulfate and polyamine depletion
Mattias Belting, Lubor Borsig, Mark M. Fuster, Jillian R. Brown, Lo Persson, Lars-Åke Fransson, and Jeffrey D. Esko
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 371–376. Published online 2001 December 18. doi: 10.1073/pnas.012346499.
PMCID: PMC117567
Optical imaging of Renilla luciferase reporter gene expression in living mice
S. Bhaumik and S. S. Gambhir
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 377–382. Published online 2001 December 18. doi: 10.1073/pnas.012611099.
PMCID: PMC117568
Selective induction of neuropilin-1 by vascular endothelial growth factor (VEGF): A mechanism contributing to VEGF-induced angiogenesis
Hideyasu Oh, Hitoshi Takagi, Atsushi Otani, Shinji Koyama, Seiji Kemmochi, Akiyoshi Uemura, and Yoshihito Honda
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 383–388. Published online 2001 December 26. doi: 10.1073/pnas.012074399.
PMCID: PMC117569
Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent
Bey-Dih Chang, Mari E. Swift, Mei Shen, Jing Fang, Eugenia V. Broude, and Igor B. Roninson
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 389–394. Published online 2001 December 18. doi: 10.1073/pnas.012602599.
PMCID: PMC117570
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
Alexandra Trkola, Shawn E. Kuhmann, Julie M. Strizki, Elizabeth Maxwell, Tom Ketas, Tom Morgan, Pavel Pugach, Serena Xu, Lisa Wojcik, Jayaram Tagat, Anandan Palani, Sherry Shapiro, John W. Clader, Stuart McCombie, Gregory R. Reyes, Bahige M. Baroudy, and John P. Moore
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 395–400. doi: 10.1073/pnas.012519099.
PMCID: PMC117571
Growth, regeneration, and tumorigenesis of the prostate activates the PSCA promoter
Tetsuro Watabe, Mark Lin, Hisamitsu Ide, Annemarie A. Donjacour, Gerald R. Cunha, Owen N. Witte, and Robert E. Reiter
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 401–406. Published online 2001 December 18. doi: 10.1073/pnas.012574899.
PMCID: PMC117572
The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice
Charles W. Joyce, Marcelo J. A. Amar, Gilles Lambert, Boris L. Vaisman, Beverly Paigen, Jamila Najib-Fruchart, Robert F. Hoyt, Jr., Edward D. Neufeld, Alan T. Remaley, Donald S. Fredrickson, H. Bryan Brewer, Jr., and Silvia Santamarina-Fojo
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 407–412. Published online 2001 December 18. doi: 10.1073/pnas.012587699.
PMCID: PMC117573
Differential long-term and multilineage engraftment potential from subfractions of human CD34+ cord blood cells transplanted into NOD/SCID mice
Christopher J. Hogan, Elizabeth J. Shpall, and Gordon Keller
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 413–418. doi: 10.1073/pnas.012336799.
PMCID: PMC117574
Increased insulin sensitivity in mice lacking p85β subunit of phosphoinositide 3-kinase
Kohjiro Ueki, Claudine M. Yballe, Saskia M. Brachmann, David Vicent, John M. Watt, C. Ronald Kahn, and Lewis C. Cantley
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 419–424. Published online 2001 December 18. doi: 10.1073/pnas.012581799.
PMCID: PMC117575
Functional self-association of von Willebrand factor during platelet adhesion under flow
Brian Savage, Jan J. Sixma, and Zaverio M. Ruggeri
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 425–430. Published online 2001 December 26. doi: 10.1073/pnas.012459599.
PMCID: PMC117576
Microbiology
Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria
Isabel Chico-Calero, Mónica Suárez, Bruno González-Zorn, Mariela Scortti, Jörg Slaghuis, Werner Goebel, The European Listeria Genome Consortium, and José A. Vázquez-Boland
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 431–436. Published online 2001 December 26. doi: 10.1073/pnas.012363899.
PMCID: PMC117577
Control of Epstein–Barr virus reactivation by activated CD40 and viral latent membrane protein 1
Barbara Adler, Eveline Schaadt, Bettina Kempkes, Ursula Zimber-Strobl, Barbara Baier, and Georg W. Bornkamm
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 437–442. Published online 2001 December 18. doi: 10.1073/pnas.221439999.
PMCID: PMC117578
The genome sequence of the facultative intracellular pathogen Brucella melitensis
Vito G. DelVecchio, Vinayak Kapatral, Rajendra J. Redkar, Guy Patra, Cesar Mujer, Tamara Los, Natalia Ivanova, Iain Anderson, Anamitra Bhattacharyya, Athanasios Lykidis, Gary Reznik, Lynn Jablonski, Niels Larsen, Mark D'Souza, Axel Bernal, Mikhail Mazur, Eugene Goltsman, Eugene Selkov, Philip H. Elzer, Sue Hagius, David O'Callaghan, Jean-Jacques Letesson, Robert Haselkorn, Nikos Kyrpides, and Ross Overbeek
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 443–448. Published online 2001 December 26. doi: 10.1073/pnas.221575398.
PMCID: PMC117579
Neurobiology
Temporal binding via cortical coincidence detection of specific and nonspecific thalamocortical inputs: A voltage-dependent dye-imaging study in mouse brain slices
Rodolfo R. Llinás, Elena Leznik, and Francisco J. Urbano
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 449–454. Published online 2002 January 2. doi: 10.1073/pnas.012604899.
PMCID: PMC117580
Functional MRI detection of pharmacologically induced memory impairment
Reisa Sperling, Douglas Greve, Anders Dale, Ronald Killiany, Jennifer Holmes, H. Diana Rosas, Andrew Cocchiarella, Paul Firth, Bruce Rosen, Stephen Lake, Nicholas Lange, Carol Routledge, and Marilyn Albert
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 455–460. Published online 2001 December 26. doi: 10.1073/pnas.012467899.
PMCID: PMC117581
Pituitary adenylate cyclase-activating polypeptide is a sympathoadrenal neurotransmitter involved in catecholamine regulation and glucohomeostasis
Carol Hamelink, Olga Tjurmina, Ruslan Damadzic, W. Scott Young, Eberhard Weihe, Hyeon-Woo Lee, and Lee E. Eiden
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 461–466. Published online 2001 December 26. doi: 10.1073/pnas.012608999.
PMCID: PMC117582
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
Shao Jun Tang, Gerald Reis, Hyejin Kang, Anne-Claude Gingras, Nahum Sonenberg, and Erin M. Schuman
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 467–472. Published online 2001 December 26. doi: 10.1073/pnas.012605299.
PMCID: PMC117583
From the Cover:
The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration
Ann H. Milam, Linda Rose, Artur V. Cideciyan, Mark R. Barakat, Wai-Xing Tang, Nisha Gupta, Tomas S. Aleman, Alan F. Wright, Edwin M. Stone, Val C. Sheffield, and Samuel G. Jacobson
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 473–478. Published online 2002 January 2. doi: 10.1073/pnas.022533099.
PMCID: PMC117584
Mice and humans perceive multiharmonic communication sounds in the same way
Günter Ehret and Sabine Riecke
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 479–482. Published online 2001 December 26. doi: 10.1073/pnas.012361999.
PMCID: PMC117585
Differential aggregation of the Trembler and Trembler J mutants of peripheral myelin protein 22
Andreas R. Tobler, Ning Liu, Lukas Mueller, and Eric M. Shooter
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 483–488. Published online 2001 December 18. doi: 10.1073/pnas.012593399.
PMCID: PMC117586
Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice in vivo
Lisa D. Wilsbacher, Shin Yamazaki, Erik D. Herzog, Eun-Joo Song, Laurel A. Radcliffe, Michikazu Abe, Gene Block, Edward Spitznagel, Michael Menaker, and Joseph S. Takahashi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 489–494. Published online 2001 December 18. doi: 10.1073/pnas.012248599.
PMCID: PMC117587
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture
Jorge E. Contreras, Helmut A. Sánchez, Eliseo A. Eugenín, Dina Speidel, Martin Theis, Klaus Willecke, Feliksas F. Bukauskas, Michael V. L. Bennett, and Juan C. Sáez
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 495–500. Published online 2001 December 26. doi: 10.1073/pnas.012589799.
PMCID: PMC117588
Pharmacology
Decreased intracellular calcium mediates the histamine H3-receptor-induced attenuation of norepinephrine exocytosis from cardiac sympathetic nerve endings
Randi B. Silver, Kumar S. Poonwasi, Nahid Seyedi, Sandy J. Wilson, Timothy W. Lovenberg, and Roberto Levi
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 501–506. Published online 2001 December 18. doi: 10.1073/pnas.012506099.
PMCID: PMC117589
On the activation of soluble guanylyl cyclase by nitric oxide
Tomas C. Bellamy, John Wood, and John Garthwaite
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 507–510. Published online 2001 December 18. doi: 10.1073/pnas.012368499.
PMCID: PMC117590
Physiology
Functional requirement of aquaporin-5 in plasma membranes of sweat glands
Lene N. Nejsum, Tae-Hwan Kwon, Uffe B. Jensen, Ornella Fumagalli, Jørgen Frøkiaer, Carissa M. Krane, Anil G. Menon, Landon S. King, Peter C. Agre, and Søren Nielsen
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 511–516. Published online 2002 January 2. doi: 10.1073/pnas.012588099.
PMCID: PMC117591
Plant Biology
Arabidopsis gp91phox homologues AtrbohD and AtrbohF are required for accumulation of reactive oxygen intermediates in the plant defense response
Miguel Angel Torres, Jeffery L. Dangl, and Jonathan D. G. Jones
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 517–522. Published online 2001 December 26. doi: 10.1073/pnas.012452499.
PMCID: PMC117592
Psychology
Dorsal anterior cingulate cortex: A role in reward-based decision making
George Bush, Brent A. Vogt, Jennifer Holmes, Anders M. Dale, Douglas Greve, Michael A. Jenike, and Bruce R. Rosen
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 523–528. Published online 2001 December 26. doi: 10.1073/pnas.012470999.
PMCID: PMC117593
From the Cover:
Brain signatures of artificial language processing: Evidence challenging the critical period hypothesis
Angela D. Friederici, Karsten Steinhauer, and Erdmut Pfeifer
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 529–534. Published online 2002 January 2. doi: 10.1073/pnas.012611199.
PMCID: PMC117594
Social Sciences
Anthropology
Phylogenetic relationships among domesticated and wild species of Cucurbita (Cucurbitaceae) inferred from a mitochondrial gene: Implications for crop plant evolution and areas of origin
Oris I. Sanjur, Dolores R. Piperno, Thomas C. Andres, and Linda Wessel-Beaver
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 535–540. doi: 10.1073/pnas.012577299.
PMCID: PMC117595
Psychology
From the Cover:
Brain signatures of artificial language processing: Evidence challenging the critical period hypothesis
Angela D. Friederici, Karsten Steinhauer, and Erdmut Pfeifer
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 529–534. Published online 2002 January 2. doi: 10.1073/pnas.012611199.
PMCID: PMC117594
Corrections
Correction
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 541. Published online 2002 January 2.
PMCID: PMC117498
Corrects: Gregory J. Adcock, et al. From the Cover:
Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins.
Proc Natl Acad Sci U S A. 2001 January 16; 98(2): 537–542.
Correction
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 541. Published online 2001 December 18.
PMCID: PMC117499
Corrects: Albrecht H. Kossel, et al. A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation. Proc Natl Acad Sci U S A. 2001 December 4; 98(25): 14702–14707.
Correction
Proc Natl Acad Sci U S A. 2002 January 8; 99(1): 541. Published online 2001 December 18.
PMCID: PMC117500
Corrects: Claudio Grosman, et al. The dissociation of acetylcholine from open nicotinic receptor channels. Proc Natl Acad Sci U S A. 2001 November 20; 98(24): 14102–14107.
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