| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 February 8; 102(6): 1809–1810. doi: 10.1073/iti0605102.PMCID: PMC548569 Commentaries Telomere maintenance by intracellular signals: New kid on the block? Stephen B. Shears PMCID: PMC548594 Inverting the selectivity of aquaporin 6: Gating versus direct electrostatic interaction Arieh Warshel PMCID: PMC548591 Plant Golgi cell wall synthesis: From genes to enzyme activities Kanwarpal S. Dhugga PMCID: PMC548580 Control improves with age: Intercellular transport in plant embryos and adults Shoko Ueki and Vitaly Citovsky PMCID: PMC548589 Physical Sciences Applied Mathematics Fluid-flow-induced flutter of a flag Médéric Argentina and L. Mahadevan PMCID: PMC548550 Chemistry Dynamics of unbinding of cell adhesion molecules: Transition from catch to slip bonds V. Barsegov and D. Thirumalai PMCID: PMC548539 Zero- to low-field MRI with averaging of concomitant gradient fields Carlos A. Meriles, Dimitris Sakellariou, Andreas H. Trabesinger, Vasiliki Demas, and Alexander Pines PMCID: PMC548560 Chemical peristalsis R. Dean Astumian PMCID: PMC548544 Wetting morphologies at microstructured surfaces Ralf Seemann, Martin Brinkmann, Edward J. Kramer, Frederick F. Lange, and Reinhard Lipowsky PMCID: PMC546015 Characterization of an organometallic xenon complex using NMR and IR spectroscopy Graham E. Ball, Tamim A. Darwish, Spili Geftakis, Michael W. George, Douglas J. Lawes, Peter Portius, and Jonathan P. Rourke PMCID: PMC548530 Geology INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Edward Irving Tinsley H. Davis PMCID: PMC548532 INAUGURAL ARTICLE by a Recently Elected Academy Member: The role of latitude in mobilism debates Edward Irving PMCID: PMC548542 Biological Sciences Biochemistry Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation Andrei Kuzmichev, Raphael Margueron, Alejandro Vaquero, Tanja S. Preissner, Michael Scher, Antonis Kirmizis, Xuesong Ouyang, Neil Brockdorff, Cory Abate-Shen, Peggy Farnham, and Danny Reinberg PMCID: PMC548563 Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis John Dresios, Armaz Aschrafi, Geoffrey C. Owens, Peter W. Vanderklish, Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC548588 From the Cover:
Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design George Kontopidis, Su-Ying Wu, Daniella I. Zheleva, Paul Taylor, Campbell McInnes, David P. Lane, Peter M. Fischer, and Malcolm D. Walkinshaw PMCID: PMC548533 Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence of histone H1 Boris Kysela, Miroslav Chovanec, and Penny A. Jeggo PMCID: PMC548527 Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity Sinisa Urban and Michael S. Wolfe PMCID: PMC548546 Biophysics De novo design of an IL-4 antagonist and its structure at 1.9 Å Sherry L. LaPorte, Charles M. Forsyth, Brian C. Cunningham, Larry J. Miercke, David Akhavan, and Robert M. Stroud PMCID: PMC548554 Cooperative behavior of Escherichia coli cell-division protein FtsZ assembly involves the preferential cyclization of long single-stranded fibrils José Manuel González, Marisela Vélez, Mercedes Jiménez, Carlos Alfonso, Peter Schuck, Jesús Mingorance, Miguel Vicente, Allen P. Minton, and Germán Rivas PMCID: PMC548572 NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline Rebecca Page, Wolfgang Peti, Ian A. Wilson, Raymond C. Stevens, and Kurt Wüthrich PMCID: PMC548552 Cell Biology Regulation of hepcidin transcription by interleukin-1 and interleukin-6 Pauline Lee, Hongfan Peng, Terri Gelbart, Lei Wang, and Ernest Beutler PMCID: PMC548537 From the Cover:
Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases Adolfo Saiardi, Adam C. Resnick, Adele M. Snowman, Beverly Wendland, and Solomon H. Snyder PMCID: PMC548528 Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: Implications for cancer immunotherapy Lilach M. Friedman, Ariel Rinon, Bilha Schechter, Ljuba Lyass, Sara Lavi, Sarah S. Bacus, Michael Sela, and Yosef Yarden PMCID: PMC548578 Gelsolin mediates calcium-dependent disassembly of Listeria actin tails Laura Larson, Serge Arnaudeau, Bruce Gibson, Wei Li, Ryoko Krause, Binghua Hao, James R. Bamburg, Daniel P. Lew, Nicolas Demaurex, and Frederick Southwick PMCID: PMC548556 Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis Jun Liu, Anne G. Bang, Chris Kintner, Anthony P. Orth, Sumit K. Chanda, Sheng Ding, and Peter G. Schultz PMCID: PMC548559 Intercellular transfer of P-glycoprotein mediates acquired multidrug resistance in tumor cells Andre Levchenko, Bipin M. Mehta, Xinle Niu, Grace Kang, Liliana Villafania, Denise Way, Dolores Polycarpe, Michel Sadelain, and Steven M. Larson PMCID: PMC545583 Potentiation of the ligand-binding activity of integrin α3β1 via association with tetraspanin CD151 Ryoko Nishiuchi, Noriko Sanzen, Shigeyuki Nada, Yasuhiro Sumida, Yoshinao Wada, Masato Okada, Junichi Takagi, Hitoshi Hasegawa, and Kiyotoshi Sekiguchi PMCID: PMC548567 E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1) Alessandro Vichi, D. Michael Payne, Gustavo Pacheco-Rodriguez, Joel Moss, and Martha Vaughan PMCID: PMC548593 Developmental Biology Computational insights into Caenorhabditis elegans vulval development Jasmin Fisher, Nir Piterman, E. Jane Albert Hubbard, Michael J. Stern, and David Harel PMCID: PMC548551 Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer Ray K. Ng and John B. Gurdon PMCID: PMC548545 Ecology Predicting the risk of extinction from shared ecological characteristics Janne S. Kotiaho, Veijo Kaitala, Atte Komonen, and Jussi Päivinen PMCID: PMC548535 Evolution Neutral microepidemic evolution of bacterial pathogens Christophe Fraser, William P. Hanage, and Brian G. Spratt PMCID: PMC548543 From the Cover:
Conserved patterns of protein interaction in multiple species Roded Sharan, Silpa Suthram, Ryan M. Kelley, Tanja Kuhn, Scott McCuine, Peter Uetz, Taylor Sittler, Richard M. Karp, and Trey Ideker PMCID: PMC548573 A monkey's tale: The origin of Plasmodium vivax as a human malaria parasite Ananias A. Escalante, Omar E. Cornejo, Denise E. Freeland, Amanda C. Poe, Ester Durrego, William E. Collins, and Altaf A. Lal PMCID: PMC548581 Complex early genes Scott W. Roy and Walter Gilbert PMCID: PMC548548 Genetics A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance Kiranmai Gumireddy, Stacey J. Baker, Stephen C. Cosenza, Premila John, Anthony D. Kang, Kimberly A. Robell, M. V. Ramana Reddy, and E. Premkumar Reddy PMCID: PMC546016 Inference of combinatorial regulation in yeast transcriptional networks: A case study of sporulation Wei Wang, J. Michael Cherry, Yigal Nochomovitz, Emmitt Jolly, David Botstein, and Hao Li PMCID: PMC548531 Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility Stefan Kammerer, Richard B. Roth, Carolyn R. Hoyal, Richard Reneland, George Marnellos, Marion Kiechle, Ulrike Schwarz-Boeger, Lyn R. Griffiths, Florian Ebner, Joachim Rehbock, Charles R. Cantor, Matthew R. Nelson, and Andreas Braun PMCID: PMC548529 Immunology Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets Bo Wei, Peter Velazquez, Olga Turovskaya, Karsten Spricher, Richard Aranda, Mitchell Kronenberg, Lutz Birnbaumer, and Jonathan Braun PMCID: PMC548553 NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression Devangi S. Mehta, Andrea L. Wurster, Amy S. Weinmann, and Michael J. Grusby PMCID: PMC548571 DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase Hitoshi Nagaoka, Satomi Ito, Masamichi Muramatsu, Mikiyo Nakata, and Tasuku Honjo PMCID: PMC548564 Down-regulation of myasthenogenic T cell responses by a dual altered peptide ligand via CD4+CD25+-regulated events leading to apoptosis Hava Ben-David, Michael Sela, and Edna Mozes PMCID: PMC548575 T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-γ promoter via a conserved T-box half-site Yingkai Tong, Thomas Aune, and Mark Boothby PMCID: PMC548570 Medical Sciences Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature Maria E. Åkerman, Jan Pilch, David Peters, and Erkki Ruoslahti PMCID: PMC548558 A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia–reperfusion injury Fabio Fiordaliso, Stefano Chimenti, Lidia Staszewsky, Antonio Bai, Eleonora Carlo, Ivan Cuccovillo, Mirko Doni, Manuela Mengozzi, Rossella Tonelli, Pietro Ghezzi, Thomas Coleman, Michael Brines, Anthony Cerami, and Roberto Latini PMCID: PMC548534 Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI) Rickard Sandberg and Ingemar Ernberg PMCID: PMC548538 Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation Kristina Schoonjans, Laurent Dubuquoy, Joseph Mebis, Elisabeth Fayard, Olivia Wendling, Céline Haby, Karel Geboes, and Johan Auwerx PMCID: PMC548586 Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury Catherine A. M. Stedman, Christopher Liddle, Sally A. Coulter, Junichiro Sonoda, Jacqueline G. A. Alvarez, David D. Moore, Ronald M. Evans, and Michael Downes PMCID: PMC548592 Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment Kara N. Maxwell, Edward A. Fisher, and Jan L. Breslow PMCID: PMC546019 Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris Francesca Chamian, Michelle A. Lowes, Shao-Lee Lin, Edmund Lee, Toyoko Kikuchi, Patricia Gilleaudeau, Mary Sullivan-Whalen, Irma Cardinale, Artemis Khatcherian, Inna Novitskaya, Knut M. Wittkowski, and James G. Krueger PMCID: PMC545584 Microbiology Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein Maria C. Silva, Jörg Schröer, and Thomas Shenk PMCID: PMC548577 Molecular characterization of proteolytic cleavage sites of the Pseudomonas syringae effector AvrRpt2 Stephen T. Chisholm, Douglas Dahlbeck, Nandini Krishnamurthy, Brad Day, Kimmen Sjolander, and Brian J. Staskawicz PMCID: PMC548309 Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision Galina N. Nikolenko, Sarah Palmer, Frank Maldarelli, John W. Mellors, John M. Coffin, and Vinay K. Pathak PMCID: PMC548555 Global profiling of Shewanella oneidensis MR-1: Expression of hypothetical genes and improved functional annotations Eugene Kolker, Alex F. Picone, Michael Y. Galperin, Margaret F. Romine, Roger Higdon, Kira S. Makarova, Natali Kolker, Gordon A. Anderson, Xiaoyun Qiu, Kenneth J. Auberry, Gyorgy Babnigg, Alex S. Beliaev, Paul Edlefsen, Dwayne A. Elias, Yuri A. Gorby, Ted Holzman, Joel A. Klappenbach, Konstantinos T. Konstantinidis, Miriam L. Land, Mary S. Lipton, Lee-Ann McCue, Matthew Monroe, Ljiljana Pasa-Tolic, Grigoriy Pinchuk, Samuel Purvine, Margrethe H. Serres, Sasha Tsapin, Brian A. Zakrajsek, Wenhong Zhu, Jizhong Zhou, Frank W. Larimer, Charles E. Lawrence, Monica Riley, Frank R. Collart, John R. Yates, III, Richard D. Smith, Carol S. Giometti, Kenneth H. Nealson, James K. Fredrickson, and James M. Tiedje PMCID: PMC548307 Neuroscience Serine racemase: Activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration Paul M. Kim, Hiroyuki Aizawa, Peter S. Kim, Alex S. Huang, Sasrutha R. Wickramasinghe, Amir H. Kashani, Roxanne K. Barrow, Richard L. Huganir, Anirvan Ghosh, and Solomon H. Snyder PMCID: PMC548584 Characterizing functional hippocampal pathways in a brain-based device as it solves a spatial memory task Jeffrey L. Krichmar, Douglas A. Nitz, Joseph A. Gally, and Gerald M. Edelman PMCID: PMC548312 Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, and Taketoshi Ono PMCID: PMC548585 A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice Verity A. Letts, Connie L. Mahaffey, Barbara Beyer, and Wayne N. Frankel PMCID: PMC548574 Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates Muhammad Shahab, Claudio Mastronardi, Stephanie B. Seminara, William F. Crowley, Sergio R. Ojeda, and Tony M. Plant PMCID: PMC548549 Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior Graziano Pinna, Erminio Costa, and Alessandro Guidotti PMCID: PMC548579 Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity Tieqiao Wen, Clayton A. Parrish, Dan Xu, Qi Wu, and Ping Shen PMCID: PMC548536 Brain correlates of subjective reality of physically and psychologically induced pain Tuukka T. Raij, Jussi Numminen, Sakari Närvänen, Jaana Hiltunen, and Riitta Hari PMCID: PMC548310 In psychosis, cortical interneurons overexpress DNA-methyltransferase 1 Marin Veldic, Alessandro Guidotti, Ekrem Maloku, John M. Davis, and Erminio Costa PMCID: PMC548582 Effects of cholinergic deafferentation of the rhinal cortex on visual recognition memory in monkeys Janita Turchi, Richard C. Saunders, and Mortimer Mishkin PMCID: PMC548583 Aggregation promoting C-terminal truncation of α-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations Wenxue Li, Neva West, Emanuela Colla, Olga Pletnikova, Juan C. Troncoso, Laura Marsh, Ted M. Dawson, Pekka Jäkälä, Tobias Hartmann, Donald L. Price, and Michael K. Lee PMCID: PMC548541 Strain-specified characteristics of mouse synthetic prions Giuseppe Legname, Hoang-Oanh B. Nguyen, Ilia V. Baskakov, Fred E. Cohen, Stephen J. DeArmond, and Stanley B. Prusiner PMCID: PMC548557 Parkin-deficient mice are not a robust model of parkinsonism Francisco A. Perez and Richard D. Palmiter PMCID: PMC548311 The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain Armaz Aschrafi, Bruce A. Cunningham, Gerald M. Edelman, and Peter W. Vanderklish PMCID: PMC548595 Pharmacology Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor Kevin R. Smith, Kent E. Pinkerton, Takaho Watanabe, Theresa L. Pedersen, Seung Jin Ma, and Bruce D. Hammock PMCID: PMC548576 Physiology From the Cover:
Conversion of aquaporin 6 from an anion channel to a water-selective channel by a single amino acid substitution Kun Liu, David Kozono, Yasuhiro Kato, Peter Agre, Akihiro Hazama, and Masato Yasui PMCID: PMC548568 Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites Junichiro Sonoda, Ling Wa Chong, Michael Downes, Grant D. Barish, Sally Coulter, Christopher Liddle, Chih-Hao Lee, and Ronald M. Evans PMCID: PMC548561 Three GnRH receptor types in laser-captured single cells of the cichlid pituitary display cellular and functional heterogeneity Ishwar S. Parhar, Satoshi Ogawa, and Yasuo Sakuma PMCID: PMC546018 From the Cover:
Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles Antonio M. Pregueiro, Nathan Price-Lloyd, Deborah Bell-Pedersen, Christian Heintzen, Jennifer J. Loros, and Jay C. Dunlap PMCID: PMC548525 ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity Christoph O. Randak and Michael J. Welsh PMCID: PMC548590 Plant Biology Expression of cellulose synthase-like (Csl) genes in insect cells reveals that CslA family members encode mannan synthases Aaron H. Liepman, Curtis G. Wilkerson, and Kenneth Keegstra PMCID: PMC548565 Cell-to-cell movement of GFP during embryogenesis and early seedling development in Arabidopsis Insoon Kim, Euna Cho, Katrina Crawford, Frederick D. Hempel, and Patricia C. Zambryski PMCID: PMC548566 Targeted mutagenesis using zinc-finger nucleases in Arabidopsis Alan Lloyd, Christopher L. Plaisier, Dana Carroll, and Gary N. Drews PMCID: PMC548540 Ricinosomes and endosperm transfer cell structure in programmed cell death of the nucellus during Ricinus seed development John S. Greenwood, Michael Helm, and Christine Gietl PMCID: PMC548547 Psychology Synchronizing to real events: Subjective audiovisual alignment scales with perceived auditory depth and speed of sound David Alais and Simon Carlile PMCID: PMC548526 Social Sciences Anthropology Demographic dynamics and kinship in anthropological populations E. A. Hammel PMCID: PMC548587 Economic Sciences The predictive power of zero intelligence in financial markets J. Doyne Farmer, Paolo Patelli, and Ilija I. Zovko PMCID: PMC548562 Correction Proc Natl Acad Sci U S A. 2005 February 8; 102(6): 2260. doi: 10.1073/pnas.0500082102.PMCID: PMC548598 Corrects: Alice Nicolas, et al. Cell mechanosensitivity controls the anisotropy of focal adhesions. Proc Natl Acad Sci U S A. 2004 August 24; 101(34): 12520–12525. |
