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Volume 102(1);  January 4, 2005
In This Issue
This Week in PNAS
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 1–2. doi: 10.1073/iti0105102.
PMCID: PMC544079
Commentary
Planting and pruning in the brain: MHC antigens involved in synaptic plasticity?
Hartmut Wekerle
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 3–4. Published online 2004 December 27. doi: 10.1073/pnas.0408495101.
PMCID: PMC544060
Biography
Biography of Joshua R. Sanes
Tinsley H. Davis
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 5–7. Published online 2004 December 27. doi: 10.1073/pnas.0408739102.
PMCID: PMC544077
Physical Sciences
Chemistry
On the capturing of low-energy electrons by DNA
S. G. Ray, S. S. Daube, and R. Naaman
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 15–19. Published online 2004 December 22. doi: 10.1073/pnas.0407020102.
PMCID: PMC544061
Photochemical selectivity in guanine–cytosine base-pair structures
Ali Abo-Riziq, Louis Grace, Eyal Nir, Martin Kabelac, Pavel Hobza, and Mattanjah S. de Vries
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 20–23. Published online 2004 December 23. doi: 10.1073/pnas.0408574102.
PMCID: PMC544067
Changes in DNA bending induced by restricting nucleotide ring pucker studied by weak alignment NMR spectroscopy
Zhengrong Wu, Melissa Maderia, Joseph J. Barchi, Jr, Victor E. Marquez, and Ad Bax
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 24–28. Published online 2004 December 23. doi: 10.1073/pnas.0408498102.
PMCID: PMC544063
Biological Sciences
Applied Biological Sciences
From the Cover:
Propagation of an infertile hermaphrodite mouse lacking germ cells by using nuclear transfer and embryonic stem cell technology
Sayaka Wakayama, Satoshi Kishigami, Nguyen Van Thuan, Hiroshi Ohta, Takafusa Hikichi, Eiji Mizutani, Ryuzo Yanagimachi, and Teruhiko Wakayama
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 29–33. Published online 2004 December 23. doi: 10.1073/pnas.0408548102.
PMCID: PMC544064
SNP detection using peptide nucleic acid probes and conjugated polymers: Applications in neurodegenerative disease identification
Brent S. Gaylord, Michelle R. Massie, Stuart C. Feinstein, and Guillermo C. Bazan
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 34–39. Published online 2004 December 23. doi: 10.1073/pnas.0407578101.
PMCID: PMC544065
Antibody buffering of a ligand in vivo
Carol E. O'Hear and Jefferson Foote
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 40–44. Published online 2004 December 22. doi: 10.1073/pnas.0405797102.
PMCID: PMC544049
Biochemistry
On the capturing of low-energy electrons by DNA
S. G. Ray, S. S. Daube, and R. Naaman
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 15–19. Published online 2004 December 22. doi: 10.1073/pnas.0407020102.
PMCID: PMC544061
The cAMP binding domain: An ancient signaling module
Helen M. Berman, Lynn F. Ten Eyck, David S. Goodsell, Nina M. Haste, Alexandr Kornev, and Susan S. Taylor
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 45–50. Published online 2004 December 23. doi: 10.1073/pnas.0408579102.
PMCID: PMC544069
The crystal structure of yeast copper thionein: The solution of a long-lasting enigma
Vito Calderone, Benedikt Dolderer, Hans-Juergen Hartmann, Hartmut Echner, Claudio Luchinat, Cristina Del Bianco, Stefano Mangani, and Ulrich Weser
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 51–56. Published online 2004 December 21. doi: 10.1073/pnas.0408254101.
PMCID: PMC544076
From the Cover:
The modular architecture of protein–protein binding interfaces
D. Reichmann, O. Rahat, S. Albeck, R. Meged, O. Dym, and G. Schreiber
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 57–62. Published online 2004 December 23. doi: 10.1073/pnas.0407280102.
PMCID: PMC544062
HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule
Baoying Liu, Sohee Hong, Zhanyun Tang, Hongtao Yu, and Chou-Zen Giam
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 63–68. Published online 2004 December 27. doi: 10.1073/pnas.0406424101.
PMCID: PMC544051
Studies of the properties of human origin recognition complex and its Walker A motif mutants
Jennifer Giordano-Coltart, Carol Y. Ying, Jean Gautier, and Jerard Hurwitz
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 69–74. Published online 2004 December 23. doi: 10.1073/pnas.0408690102.
PMCID: PMC544074
Sequential multiple functions of the conserved sequence in sequence-specific termination by T7 RNA polymerase
Younghee Sohn and Changwon Kang
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 75–80. Published online 2004 December 22. doi: 10.1073/pnas.0406581101.
PMCID: PMC544054
Biophysics
Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation
Andrea Balbo, Kenneth H. Minor, Carlos A. Velikovsky, Roy A. Mariuzza, Cynthia B. Peterson, and Peter Schuck
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 81–86. Published online 2004 December 21. doi: 10.1073/pnas.0408399102.
PMCID: PMC538923
A speed limit for conformational change of an allosteric membrane protein
Sudha Chakrapani and Anthony Auerbach
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 87–92. Published online 2004 December 23. doi: 10.1073/pnas.0406777102.
PMCID: PMC544059
Cell Biology
Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway
Andrey A. Sharov, Michael Fessing, Ruzanna Atoyan, Tatyana Y. Sharova, Carrie Haskell-Luevano, Lorin Weiner, Keiko Funa, Janice L. Brissette, Barbara A. Gilchrest, and Vladimir A. Botchkarev
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 93–98. Published online 2004 December 23. doi: 10.1073/pnas.0408455102.
PMCID: PMC544050
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
Sarah L. Pull, Jason M. Doherty, Jason C. Mills, Jeffrey I. Gordon, and Thaddeus S. Stappenbeck
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 99–104. Published online 2004 December 22. doi: 10.1073/pnas.0405979102.
PMCID: PMC544052
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
Scott A. Oakes, Luca Scorrano, Joseph T. Opferman, Michael C. Bassik, Mari Nishino, Tullio Pozzan, and Stanley J. Korsmeyer
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 105–110. Published online 2004 December 21. doi: 10.1073/pnas.0408352102.
PMCID: PMC544078
Endometrial cancer is a receptor-mediated target for Mullerian Inhibiting Substance
Elizabeth J. Renaud, David T. MacLaughlin, Esther Oliva, Bo R. Rueda, and Patricia K. Donahoe
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 111–116. Published online 2004 December 23. doi: 10.1073/pnas.0407772101.
PMCID: PMC544070
S-nitrosoprotein formation and localization in endothelial cells
Yi Yang and Joseph Loscalzo
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 117–122. Published online 2004 December 23. doi: 10.1073/pnas.0405989102.
PMCID: PMC544053
Rapid biogenesis and sensitization of secretory lysosomes in NK cells mediated by target-cell recognition
Dongfang Liu, Liang Xu, Fan Yang, Dongdong Li, Feili Gong, and Tao Xu
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 123–127. Published online 2004 December 23. doi: 10.1073/pnas.0405737102.
PMCID: PMC544047
Developmental Biology
Microvascular patterning is controlled by fine-tuning the Akt signal
Jing Fang Sun, Thuy Phung, Ichiro Shiojima, Terri Felske, J. Nalinee Upalakalin, Dian Feng, Tad Kornaga, Talia Dor, Ann M. Dvorak, Kenneth Walsh, and Laura E. Benjamin
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 128–133. Published online 2004 December 20. doi: 10.1073/pnas.0403198102.
PMCID: PMC538747
Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin
Julien Y. Bertrand, Sébastien Giroux, Rachel Golub, Michèle Klaine, Abdelali Jalil, Laurent Boucontet, Isabelle Godin, and Ana Cumano
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 134–139. Published online 2004 December 27. doi: 10.1073/pnas.0402270102.
PMCID: PMC544043
Evolution
The rate of DNA evolution: Effects of body size and temperature on the molecular clock
James F. Gillooly, Andrew P. Allen, Geoffrey B. West, and James H. Brown
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 140–145. Published online 2004 December 23. doi: 10.1073/pnas.0407735101.
PMCID: PMC544068
Identification of a nematode chemosensory gene family
Nansheng Chen, Shraddha Pai, Zhongying Zhao, Allan Mah, Rebecca Newbury, Robert C. Johnsen, Zeynep Altun, Donald G. Moerman, David L. Baillie, and Lincoln D. Stein
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 146–151. Published online 2004 December 23. doi: 10.1073/pnas.0408307102.
PMCID: PMC539308
Genetics
From the Cover:
RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production
Tomoyasu Sugiyama, Hugh Cam, André Verdel, Danesh Moazed, and Shiv I. S. Grewal
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 152–157. Published online 2004 December 22. doi: 10.1073/pnas.0407641102.
PMCID: PMC544066
gerbil: Genotype resolution and block identification using likelihood
Gad Kimmel and Ron Shamir
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 158–162. Published online 2004 December 22. doi: 10.1073/pnas.0404730102.
PMCID: PMC544046
The splicing of yeast mitochondrial group I and group II introns requires a DEAD-box protein with RNA chaperone function
Hon-Ren Huang, Claire E. Rowe, Sabine Mohr, Yue Jiang, Alan M. Lambowitz, and Philip S. Perlman
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 163–168. Published online 2004 December 23. doi: 10.1073/pnas.0407896101.
PMCID: PMC544071
Immunology
The descent of the antibody-based immune system by gradual evolution
Jan Klein and Nikolas Nikolaidis
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 169–174. Published online 2004 December 23. doi: 10.1073/pnas.0408480102.
PMCID: PMC544055
Medical Sciences
Reactive oxygen signaling and MAPK activation distinguish Epstein–Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma
Francesca Cerimele, Traci Battle, Rebecca Lynch, David A. Frank, Emma Murad, Cynthia Cohen, Nada Macaron, John Sixbey, Kenneth Smith, Randolph S. Watnick, Aristidis Eliopoulos, Bahig Shehata, and Jack L. Arbiser
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 175–179. Published online 2004 December 20. doi: 10.1073/pnas.0408381102.
PMCID: PMC544042
Impaired up-regulation of CD25 on CD4+ T cells in IFN-γ knockout mice is associated with progression of myocarditis to heart failure
Marina Afanasyeva, Dimitrios Georgakopoulos, Diego F. Belardi, Djahida Bedja, DeLisa Fairweather, Yan Wang, Ziya Kaya, Kathleen L. Gabrielson, E. Rene Rodriguez, Patrizio Caturegli, David A. Kass, and Noel R. Rose
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 180–185. Published online 2004 December 20. doi: 10.1073/pnas.0408241102.
PMCID: PMC544075
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis
Guoshun Wang, Bruce A. Bunnell, Richard G. Painter, Blesilda C. Quiniones, Susan Tom, Nicholas A. Lanson, Jr, Jeffrey L. Spees, Donna Bertucci, Alexandra Peister, Daniel J. Weiss, Vincent G. Valentine, Darwin J. Prockop, and Jay K. Kolls
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 186–191. Published online 2004 December 22. doi: 10.1073/pnas.0406266102.
PMCID: PMC544045
Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis
Hamdiye Erdal, Maria Berndtsson, Juan Castro, Ulf Brunk, Maria C. Shoshan, and Stig Linder
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 192–197. Published online 2004 December 23. doi: 10.1073/pnas.0408592102.
PMCID: PMC544072
From the Cover:
Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles
Qi Long Lu, Adam Rabinowitz, Yun Chao Chen, Toshifumi Yokota, HaiFang Yin, Julia Alter, Atif Jadoon, George Bou-Gharios, and Terence Partridge
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 198–203. Published online 2004 December 17. doi: 10.1073/pnas.0406700102.
PMCID: PMC544058
Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis
Philip M. Bauer, Jun Yu, Yan Chen, Reed Hickey, Pascal N. Bernatchez, Robin Looft-Wilson, Yan Huang, Frank Giordano, Radu V. Stan, and William C. Sessa
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 204–209. Published online 2004 December 22. doi: 10.1073/pnas.0406092102.
PMCID: PMC544041
Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate
David R. Shaffer, Agnes Viale, Ryota Ishiwata, Margaret Leversha, Semra Olgac, Katia Manova, Jaya Satagopan, Howard Scher, and Andrew Koff
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 210–215. Published online 2004 December 22. doi: 10.1073/pnas.0407362102.
PMCID: PMC539141
Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets
Li Ma, Rafael Perini, Webb McKnight, Michael Dicay, Andre Klein, Morley D. Hollenberg, and John L. Wallace
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 216–220. Published online 2004 December 22. doi: 10.1073/pnas.0406682102.
PMCID: PMC544057
Microbiology
From the Cover:
An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporter
Rose L. Szabady, Janine H. Peterson, Kristen M. Skillman, and Harris D. Bernstein
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 221–226. Published online 2004 December 22. doi: 10.1073/pnas.0406055102.
PMCID: PMC544056
Neuroscience
Gamma protocadherins are required for synaptic development in the spinal cord
Joshua A. Weiner, Xiaozhong Wang, Juan Carlos Tapia, and Joshua R. Sanes
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 8–14. Published online 2004 December 1. doi: 10.1073/pnas.0407931101.
PMCID: PMC544073
Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model
Bin Zhang, Arpita Maiti, Sharon Shively, Fara Lakhani, Gaye McDonald-Jones, Jennifer Bruce, Edward B. Lee, Sharon X. Xie, Sonali Joyce, Chi Li, Philip M. Toleikis, Virginia M.-Y. Lee, and John Q. Trojanowski
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 227–231. Published online 2004 December 22. doi: 10.1073/pnas.0406361102.
PMCID: PMC544048
θ frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus
Yan-You Huang and Eric R. Kandel
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 232–237. Published online 2004 December 27. doi: 10.1073/pnas.0408368102.
PMCID: PMC539311
Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease
Roberto Chiesa, Pedro Piccardo, Sara Dossena, Lisa Nowoslawski, Kevin A. Roth, Bernardino Ghetti, and David A. Harris
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 238–243. Published online 2004 December 23. doi: 10.1073/pnas.0406173102.
PMCID: PMC544044
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription
Marcus J. Calkins, Rebekah J. Jakel, Delinda A. Johnson, Kaimin Chan, Yuet Wai Kan, and Jeffrey A. Johnson
Proc Natl Acad Sci U S A. 2005 January 4; 102(1): 244–249. Published online 2004 December 20. doi: 10.1073/pnas.0408487101.
PMCID: PMC538748
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