| | This journal provides immediate access to some articles. Commentaries Organismal stress and telomeric aging: An unexpected connection Robert M. Sapolsky Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17323–17324. Published online 2004 December 3. doi: 10.1073/pnas.0408041101.PMCID: PMC536029 A multiple-levels-of-analysis approach to the study of developmental processes in maltreated children Dante Cicchetti and Jennifer A. Blender Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17325–17326. Published online 2004 December 6. doi: 10.1073/pnas.0408033101.PMCID: PMC536022 Φ value versus ψ analysis Alan R. Fersht Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17327–17328. Published online 2004 December 6. doi: 10.1073/pnas.0407863101.PMCID: PMC536033 Fragile X syndrome: (What's) lost in translation? Kevin Miyashiro and James Eberwine Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17329–17330. Published online 2004 December 6. doi: 10.1073/pnas.0408034101.PMCID: PMC536026 Physical Sciences Applied Physical Sciences From the Cover: Ordered patterns of liquid crystal toroidal defects by microchannel confinement Myung Chul Choi, Thomas Pfohl, Zhiyu Wen, Youli Li, Mahn Won Kim, Jacob N. Israelachvili, and Cyrus R. Safinya Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17340–17344. Published online 2004 November 30. doi: 10.1073/pnas.0407925101.PMCID: PMC536040 In silico study of amyloid β-protein folding and oligomerization B. Urbanc, L. Cruz, S. Yun, S. V. Buldyrev, G. Bitan, D. B. Teplow, and H. E. Stanley Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17345–17350. Published online 2004 December 6. doi: 10.1073/pnas.0408153101.PMCID: PMC536046 Chemistry The structure of carbonmonoxy neuroglobin reveals a heme-sliding mechanism for control of ligand affinity Beatrice Vallone, Karin Nienhaus, Annemarie Matthes, Maurizio Brunori, and G. Ulrich Nienhaus Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17351–17356. Published online 2004 November 17. doi: 10.1073/pnas.0407633101.PMCID: PMC536024 Mathematics Unexpected connections between Burnside groups and knot theory Mieczyslaw K. Dabkowski and Józef H. Przytycki Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17357–17360. Published online 2004 December 2. doi: 10.1073/pnas.0406098101.PMCID: PMC536021 Biological Sciences Biochemistry The structure of carbonmonoxy neuroglobin reveals a heme-sliding mechanism for control of ligand affinity Beatrice Vallone, Karin Nienhaus, Annemarie Matthes, Maurizio Brunori, and G. Ulrich Nienhaus Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17351–17356. Published online 2004 November 17. doi: 10.1073/pnas.0407633101.PMCID: PMC536024 Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center Nizar N. Batada, Kenneth D. Westover, David A. Bushnell, Michael Levitt, and Roger D. Kornberg Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17361–17364. Published online 2004 December 1. doi: 10.1073/pnas.0408168101.PMCID: PMC536049 The bacteriophage T4 late-transcription coactivator gp33 binds the flap domain of Escherichia coli RNA polymerase Sergei Nechaev, Masood Kamali-Moghaddam, Estelle André, Jean-Paul Léonetti, and E. Peter Geiduschek Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17365–17370. Published online 2004 December 1. doi: 10.1073/pnas.0408028101.PMCID: PMC535105 Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG Katja Wenig, Lorenz Chatwell, Ulrich von Pawel-Rammingen, Lars Björck, Robert Huber, and Peter Sondermann Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17371–17376. Published online 2004 December 1. doi: 10.1073/pnas.0407965101.PMCID: PMC536041 Biophysics In silico study of amyloid β-protein folding and oligomerization B. Urbanc, L. Cruz, S. Yun, S. V. Buldyrev, G. Bitan, D. B. Teplow, and H. E. Stanley Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17345–17350. Published online 2004 December 6. doi: 10.1073/pnas.0408153101.PMCID: PMC536046 Differences in the folding transition state of ubiquitin indicated by ![[var phi]](corehtml/pmc/pmcents/x03C6.gif) and ψ analyses Tobin R. Sosnick, Robin S. Dothager, and Bryan A. Krantz Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17377–17382. Published online 2004 December 2. doi: 10.1073/pnas.0407683101.PMCID: PMC536030 Inhaling to mitigate exhaled bioaerosols David A. Edwards, Jonathan C. Man, Peter Brand, Jeffrey P. Katstra, K. Sommerer, Howard A. Stone, Edward Nardell, and Gerhard Scheuch Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17383–17388. Published online 2004 December 6. doi: 10.1073/pnas.0408159101.PMCID: PMC536048 Catalysis of protein folding by chaperones in pathogenic bacteria James G. Bann, Jerome S. Pinkner, Carl Frieden, and Scott J. Hultgren Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17389–17393. Published online 2004 December 6. doi: 10.1073/pnas.0408072101.PMCID: PMC536034 Protein chemical shifts arising from α-helices and β-sheets depend on solvent exposure Franc Avbelj, Darko Kocjan, and Robert L. Baldwin Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17394–17397. Published online 2004 December 1. doi: 10.1073/pnas.0407969101.PMCID: PMC536043 Cell Biology Regulation of flagellar dynein activity by a central pair kinesin Ruth Yokoyama, Eileen O'Toole, Sudipto Ghosh, and David R. Mitchell Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17398–17403. Published online 2004 November 30. doi: 10.1073/pnas.0406817101.PMCID: PMC536025 Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor Amy E. Palmer, Can Jin, John C. Reed, and Roger Y. Tsien Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17404–17409. Published online 2004 December 7. doi: 10.1073/pnas.0408030101.PMCID: PMC535104 Structure of the complex between the cytosolic chaperonin CCT and phosducin-like protein Jaime Martín-Benito, Sara Bertrand, Ting Hu, Paul J. Ludtke, Joseph N. McLaughlin, Barry M. Willardson, José L. Carrascosa, and José M. Valpuesta Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17410–17415. Published online 2004 December 6. doi: 10.1073/pnas.0405070101.PMCID: PMC536017 IκB kinase β phosphorylates Dok1 serines in response to TNF, IL-1, or γ radiation Sanghoon Lee, Charlotte Andrieu, Frédéric Saltel, Olivier Destaing, Jessie Auclair, Véronique Pouchkine, Jocelyne Michelon, Bruno Salaun, Ryuji Kobayashi, Pierre Jurdic, Elliott D. Kieff, and Bakary S. Sylla Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17416–17421. Published online 2004 December 1. doi: 10.1073/pnas.0408061101.PMCID: PMC536032 The Saccharomyces cerevisiae aquaporin Aqy1 is involved in sporulation Frédéric Sidoux-Walter, Nina Pettersson, and Stefan Hohmann Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17422–17427. Published online 2004 December 6. doi: 10.1073/pnas.0404337101.PMCID: PMC536013 Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein Shuo-Chien Ling, Peter S. Fahrner, William T. Greenough, and Vladimir I. Gelfand Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17428–17433. Published online 2004 December 6. doi: 10.1073/pnas.0408114101.PMCID: PMC536039 The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport Anikó Náray-Fejes-Tóth, Peter M. Snyder, and Géza Fejes-Tóth Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17434–17439. Published online 2004 December 6. doi: 10.1073/pnas.0408146101.PMCID: PMC536044 Ecology Familiar route loyalty implies visual pilotage in the homing pigeon Dora Biro, Jessica Meade, and Tim Guilford Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17440–17443. Published online 2004 November 30. doi: 10.1073/pnas.0406984101.PMCID: PMC536010 Evolution Heterogeneous evolutionary processes affect R gene diversity in natural populations of Solanum pimpinellifolium Ana L. Caicedo and Barbara A. Schaal Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17444–17449. Published online 2004 December 6. doi: 10.1073/pnas.0407899101.PMCID: PMC536038 Genetics Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome Brian P. Chadwick and Huntington F. Willard Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17450–17455. Published online 2004 December 1. doi: 10.1073/pnas.0408021101.PMCID: PMC534659 Medical Sciences Sole BCR-ABL inhibition is insufficient to eliminate all myeloproliferative disorder cell populations S. Wong, J. McLaughlin, D. Cheng, C. Zhang, K. M. Shokat, and O. N. Witte Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17456–17461. Published online 2004 October 25. doi: 10.1073/pnas.0407061101.PMCID: PMC524218 Molecular and genetic analysis of disseminated neoplastic cells in lymphangioleiomyomatosis Denise M. Crooks, Gustavo Pacheco-Rodriguez, Rosamma M. DeCastro, J. Philip McCoy, Jr., Ji-an Wang, Fumiyuki Kumaki, Thomas Darling, and Joel Moss Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17462–17467. Published online 2004 December 6. doi: 10.1073/pnas.0407971101.PMCID: PMC536045 From the Cover: 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-β-induced suppressor of human gastrointestinal cancers Min Yan, Ronald M. Rerko, Petra Platzer, Dawn Dawson, Joseph Willis, Min Tong, Earl Lawrence, James Lutterbaugh, Shilong Lu, James K. V. Willson, Guangbin Luo, Jack Hensold, Hsin-Hsiung Tai, Keith Wilson, and Sanford D. Markowitz Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17468–17473. Published online 2004 December 1. doi: 10.1073/pnas.0406142101.PMCID: PMC536023 Microbiology Cell-surface expression of a mutated Epstein–Barr virus glycoprotein B allows fusion independent of other viral proteins Marisa P. McShane and Richard Longnecker Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17474–17479. Published online 2004 December 6. doi: 10.1073/pnas.0404535101.PMCID: PMC536015 From the Cover: Three-dimensional structure and organization of a receptor/signaling complex Noreen R. Francis, Peter M. Wolanin, Jeffry B. Stock, David J. DeRosier, and Dennis R. Thomas Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17480–17485. Published online 2004 November 30. doi: 10.1073/pnas.0407826101.PMCID: PMC536031 Subcellular distribution of enzyme I of the Escherichia coli phosphoenolpyruvate:glycose phosphotransferase system depends on growth conditions Himatkumar V. Patel, Kavita A. Vyas, Xibing Li, Regina Savtchenko, and Saul Roseman Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17486–17491. Published online 2004 November 22. doi: 10.1073/pnas.0407865101.PMCID: PMC536035 Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses Amita Sharma and Ayub Qadri Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17492–17497. Published online 2004 December 2. doi: 10.1073/pnas.0407536101.PMCID: PMC536020 Use of herpes simplex virus and pseudorabies virus chimeric glycoprotein D molecules to identify regions critical for membrane fusion Anna Zago, Cheryl R. Jogger, and Patricia G. Spear Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17498–17503. Published online 2004 December 6. doi: 10.1073/pnas.0408186101.PMCID: PMC536050 Neuroscience From the Cover: Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses Ivan Jeanne Weiler, Chad C. Spangler, Anna Y. Klintsova, Aaron W. Grossman, Soong Ho Kim, Valerie Bertaina-Anglade, Hooma Khaliq, Froukje E. de Vries, Femke A. E. Lambers, Fatima Hatia, Christine K. Base, and William T. Greenough Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17504–17509. Published online 2004 November 17. doi: 10.1073/pnas.0407533101.PMCID: PMC536018 Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease Christophe Lo Bianco, Bernard L. Schneider, Matthias Bauer, Ali Sajadi, Alexis Brice, Takeshi Iwatsubo, and Patrick Aebischer Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17510–17515. Published online 2004 December 2. doi: 10.1073/pnas.0405313101.PMCID: PMC536019 Toward an evolutionary perspective on conceptual representation: Species-specific calls activate visual and affective processing systems in the macaque Ricardo Gil-da-Costa, Allen Braun, Marco Lopes, Marc D. Hauser, Richard E. Carson, Peter Herscovitch, and Alex Martin Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17516–17521. Published online 2004 December 6. doi: 10.1073/pnas.0408077101.PMCID: PMC536037 Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy Mohsin Raza, Robert E. Blair, Sompong Sombati, Dawn S. Carter, Laxmikant S. Deshpande, and Robert J. DeLorenzo Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17522–17527. Published online 2004 December 6. doi: 10.1073/pnas.0408155101.PMCID: PMC535000 Radial glia give rise to adult neural stem cells in the subventricular zone Florian T. Merkle, Anthony D. Tramontin, José Manuel García-Verdugo, and Arturo Alvarez-Buylla Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17528–17532. Published online 2004 December 1. doi: 10.1073/pnas.0407893101.PMCID: PMC536036 Physiology Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes Peter J. Mohler, Ilaria Rivolta, Carlo Napolitano, Guy LeMaillet, Stephen Lambert, Silvia G. Priori, and Vann Bennett Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17533–17538. Published online 2004 December 3. doi: 10.1073/pnas.0403711101.PMCID: PMC536011 Molecular basis of Kir6.2 mutations associated with neonatal diabetes or neonatal diabetes plus neurological features Peter Proks, Jennifer F. Antcliff, Jon Lippiat, Anna L. Gloyn, Andrew T. Hattersley, and Frances M. Ashcroft Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17539–17544. Published online 2004 December 6. doi: 10.1073/pnas.0404756101.PMCID: PMC536014 Common scale-invariant patterns of sleep–wake transitions across mammalian species Chung-Chuan Lo, Thomas Chou, Thomas Penzel, Thomas E. Scammell, Robert E. Strecker, H. Eugene Stanley, and Plamen Ch. Ivanov Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17545–17548. Published online 2004 December 6. doi: 10.1073/pnas.0408242101.PMCID: PMC536051 Plant Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of J. Clark Lagarias Tinsley H. Davis Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17331–17333. Published online 2004 December 6. doi: 10.1073/pnas.0408338102.PMCID: PMC536052 INAUGURAL ARTICLE by a Recently Elected Academy Member: Harnessing phytochrome's glowing potential Amanda J. Fischer and J. Clark Lagarias Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17334–17339. Published online 2004 November 17. doi: 10.1073/pnas.0407645101.PMCID: PMC536027 Two perfectly conserved arginine residues are required for substrate binding in a high-affinity nitrate transporter Shiela E. Unkles, Duncan A. Rouch, Ye Wang, M. Yaeesh Siddiqi, Anthony D. M. Glass, and James R. Kinghorn Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17549–17554. Published online 2004 December 2. doi: 10.1073/pnas.0405054101.PMCID: PMC536016 Evolution of xylem lignification and hydrogel transport regulation C. Kevin Boyce, Maciej A. Zwieniecki, George D. Cody, Chris Jacobsen, Sue Wirick, Andrew H. Knoll, and N. Michele Holbrook Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17555–17558. Published online 2004 December 1. doi: 10.1073/pnas.0408024101.PMCID: PMC536047 Population Biology From the Cover: Regulation of behavioral maturation by a primer pheromone produced by adult worker honey bees Isabelle Leoncini, Yves Le Conte, Guy Costagliola, Erika Plettner, Amy L. Toth, Mianwei Wang, Zachary Huang, Jean-Marc Bécard, Didier Crauser, Keith N. Slessor, and Gene E. Robinson Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17559–17564. Published online 2004 November 30. doi: 10.1073/pnas.0407652101.PMCID: PMC536028 Corrections Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17565. doi: 10.1073/pnas.0404694101.PMCID: PMC536009 Corrects: Bibiana Bielekova, et al. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon β. Proc Natl Acad Sci U S A. 2004 June 8; 101(23): 8705–8708. Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17565. doi: 10.1073/pnas.0408124101.PMCID: PMC536042 Corrects: Dafang Wan, et al. Large-scale cDNA transfection screening for genes related to cancer development and progression. Proc Natl Acad Sci U S A. 2004 November 2; 101(44): 15724–15729. Proc Natl Acad Sci U S A. 2004 December 14; 101(50): 17565. doi: 10.1073/pnas.0408339101.PMCID: PMC536053 Corrects: Joshua I. Armstrong, et al. Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis. Proc Natl Acad Sci U S A. 2004 October 12; 101(41): 14978–14983. |