| | This journal provides immediate access to some articles. Commentary Alerting dendritic cells to pathogens: The importance of Toll-like receptor signaling of stromal cells Marco Colonna Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16083–16084. Published online 2004 November 8. doi: 10.1073/pnas.0407202101.PMCID: PMC528949 Perspective Inorganic polyphosphate in the origin and survival of species Michael R. W. Brown and Arthur Kornberg Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16085–16087. Published online 2004 November 1. doi: 10.1073/pnas.0406909101.PMCID: PMC528972 Biography INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Peter H. Quail Oliver Yun Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16088–16090. Published online 2004 November 8. doi: 10.1073/pnas.0407723101.PMCID: PMC528985 Physical Sciences Applied Physical Sciences From the Cover: Higher-order assembly of microtubules by counterions: From hexagonal bundles to living necklaces Daniel J. Needleman, Miguel A. Ojeda-Lopez, Uri Raviv, Herbert P. Miller, Leslie Wilson, and Cyrus R. Safinya Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16099–16103. Published online 2004 November 8. doi: 10.1073/pnas.0406076101.PMCID: PMC528963 Chemistry Guiding neuronal development with in situ microfabrication Bryan Kaehr, Richard Allen, David J. Javier, John Currie, and Jason B. Shear Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16104–16108. Published online 2004 November 8. doi: 10.1073/pnas.0407204101.PMCID: PMC528953 Environmental Sciences Greenhouse gas growth rates James Hansen and Makiko Sato Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16109–16114. Published online 2004 November 9. doi: 10.1073/pnas.0406982101.PMCID: PMC526279 The influence of large-scale wind power on global climate David W. Keith, Joseph F. DeCarolis, David C. Denkenberger, Donald H. Lenschow, Sergey L. Malyshev, Stephen Pacala, and Philip J. Rasch Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16115–16120. Published online 2004 November 9. doi: 10.1073/pnas.0406930101.PMCID: PMC526278 Geology Formation of tabular single-domain magnetite induced by Geobacter metallireducens GS-15 Hojatollah Vali, Benjamin Weiss, Yi-Liang Li, S. Kelly Sears, Soon Sam Kim, Joseph L. Kirschvink, and Chuanlun L. Zhang Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16121–16126. Published online 2004 November 3. doi: 10.1073/pnas.0404040101.PMCID: PMC528942 Mathematics A combinatorial model for the Macdonald polynomials J. Haglund Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16127–16131. Published online 2004 November 8. doi: 10.1073/pnas.0405567101.PMCID: PMC528938 Statistics Tropical geometry of statistical models Lior Pachter and Bernd Sturmfels Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16132–16137. Published online 2004 November 8. doi: 10.1073/pnas.0406010101.PMCID: PMC528960 Parametric inference for biological sequence analysis Lior Pachter and Bernd Sturmfels Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16138–16143. Published online 2004 November 8. doi: 10.1073/pnas.0406011101.PMCID: PMC528961 Biological Sciences Applied Biological Sciences From the Cover: Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens Steve N. Bailey, David M. Sabatini, and Brent R. Stockwell Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16144–16149. Published online 2004 November 8. doi: 10.1073/pnas.0404425101.PMCID: PMC528944 Transgenic mice expressing a soluble form of porcine nectin-1/herpesvirus entry mediator C as a model for pseudorabies-resistant livestock Etsuro Ono, Keiko Amagai, Satoshi Taharaguchi, Yukiko Tomioka, Saori Yoshino, Yuki Watanabe, Pierre Cherel, Louis-Marie Houdebine, Micheline Adam, Marc Eloit, Manabu Inobe, and Toshimitsu Uede Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16150–16155. Published online 2004 November 8. doi: 10.1073/pnas.0405816101.PMCID: PMC528950 Biochemistry Atomic structure of a tryptophan-zipper pentamer Jie Liu, Wei Yong, Yiqun Deng, Neville R. Kallenbach, and Min Lu Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16156–16161. Published online 2004 November 1. doi: 10.1073/pnas.0405319101.PMCID: PMC528954 Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling l-selenocysteine and Sps2 for selenite assimilation Takashi Tamura, Shinpei Yamamoto, Muneaki Takahata, Hiromich Sakaguchi, Hidehiko Tanaka, Thressa C. Stadtman, and Kenji Inagaki Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16162–16167. Published online 2004 November 8. doi: 10.1073/pnas.0406313101.PMCID: PMC528966 Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing Jesse S. Wright, III, Gholson J. Lyon, Elizabeth A. George, Tom W. Muir, and Richard P. Novick Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16168–16173. Published online 2004 November 4. doi: 10.1073/pnas.0404039101.PMCID: PMC528941 Biophysics Transition state and encounter complex for fast association of cytochrome c2 with bacterial reaction center Osamu Miyashita, José N. Onuchic, and Melvin Y. Okamura Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16174–16179. Published online 2004 November 1. doi: 10.1073/pnas.0405745101.PMCID: PMC528947 Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides Hung D. Nguyen and Carol K. Hall Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16180–16185. Published online 2004 November 8. doi: 10.1073/pnas.0407273101.PMCID: PMC526199 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis Shuchismita Dutta, Ying Li, Donald Johnson, Leonid Dzantiev, Charles C. Richardson, Louis J. Romano, and Tom Ellenberger Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16186–16191. Published online 2004 November 4. doi: 10.1073/pnas.0406516101.PMCID: PMC528967 Exploring the energy landscape of GFP by single-molecule mechanical experiments Hendrik Dietz and Matthias Rief Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16192–16197. Published online 2004 November 5. doi: 10.1073/pnas.0404549101.PMCID: PMC528946 Electron transfer between hemes in mammalian cytochrome c oxidase Eric Pilet, Audrius Jasaitis, Ursula Liebl, and Marten H. Vos Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16198–16203. Published online 2004 November 8. doi: 10.1073/pnas.0405032101.PMCID: PMC528948 Cell Biology Reversion of the Jun-induced oncogenic phenotype by enhanced synthesis of sialosyllactosylceramide (GM3 ganglioside) Yutaka Miura, Mami Kainuma, Hao Jiang, Hershey Velasco, Peter K. Vogt, and Senitiroh Hakomori Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16204–16209. Published online 2004 November 8. doi: 10.1073/pnas.0407297101.PMCID: PMC528971 The axonal attractant Netrin-1 is an angiogenic factor Kye Won Park, Dana Crouse, Mark Lee, Satyajit K. Karnik, Lise K. Sorensen, Kelly J. Murphy, Calvin J. Kuo, and Dean Y. Li Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16210–16215. Published online 2004 November 1. doi: 10.1073/pnas.0405984101.PMCID: PMC528958 Developmental Biology Genes required for Drosophila nervous system development identified by RNA interference Andrej I. Ivanov, Alessandra C. Rovescalli, Paola Pozzi, Siuk Yoo, Brian Mozer, Hsi-Ping Li, Shu-Hua Yu, Haruhiro Higashida, Vicky Guo, Michael Spencer, and Marshall Nirenberg Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16216–16221. Published online 2004 November 8. doi: 10.1073/pnas.0407188101.PMCID: PMC528945 Ecology Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei Jörn Piel, Dequan Hui, Gaiping Wen, Daniel Butzke, Matthias Platzer, Nobuhiro Fusetani, and Shigeki Matsunaga Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16222–16227. Published online 2004 November 1. doi: 10.1073/pnas.0405976101.PMCID: PMC528957 Evolution Convergent evolution of behavior in an adaptive radiation of Hawaiian web-building spiders Todd A. Blackledge and Rosemary G. Gillespie Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16228–16233. Published online 2004 November 1. doi: 10.1073/pnas.0407395101.PMCID: PMC528981 Genetics Interacting models of cooperative gene regulation Debopriya Das, Nilanjana Banerjee, and Michael Q. Zhang Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16234–16239. Published online 2004 November 8. doi: 10.1073/pnas.0407365101.PMCID: PMC528978 Hematopoietic gene expression profile in zebrafish kidney marrow Huai-Dong Song, Xiao-Jian Sun, Min Deng, Guo-Wei Zhang, Yi Zhou, Xin-Yan Wu, Yan Sheng, Yi Chen, Zheng Ruan, Chun-Lei Jiang, Hui-Yong Fan, Leonard I. Zon, John P. Kanki, Ting Xi Liu, A. Thomas Look, and Zhu Chen Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16240–16245. Published online 2004 November 1. doi: 10.1073/pnas.0407241101.PMCID: PMC528959 Evolving protein functional diversity in new genes of Drosophila Jianming Zhang, Antony M. Dean, Frédéric Brunet, and Manyuan Long Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16246–16250. Published online 2004 November 8. doi: 10.1073/pnas.0407066101.PMCID: PMC528974 A screen for genes that suppress loss of contact inhibition: Identification of ING4 as a candidate tumor suppressor gene in human cancer Suwon Kim, Koei Chin, Joe W. Gray, and J. Michael Bishop Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16251–16256. Published online 2004 November 4. doi: 10.1073/pnas.0407158101.PMCID: PMC528940 From the Cover: Resolution and evolution of the duck-billed platypus karyotype with an X1Y1X2Y2X3Y3X4Y4X5Y5 male sex chromosome constitution Willem Rens, Frank Grützner, Patricia C. M. O'Brien, Helen Fairclough, Jennifer A. M. Graves, and Malcolm A. Ferguson-Smith Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16257–16261. Published online 2004 November 8. doi: 10.1073/pnas.0405702101.PMCID: PMC528943 RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation Elena A. Kouzminova, Ella Rotman, Lee Macomber, Jian Zhang, and Andrei Kuzminov Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16262–16267. Published online 2004 November 5. doi: 10.1073/pnas.0405943101.PMCID: PMC528955 Immunology Crystal structure of a human CD3-ε/δ dimer in complex with a UCHT1 single-chain antibody fragment Kelly L. Arnett, Stephen C. Harrison, and Don C. Wiley Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16268–16273. Published online 2004 November 8. doi: 10.1073/pnas.0407359101.PMCID: PMC528977 From the Cover: Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments Ayuko Sato and Akiko Iwasaki Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16274–16279. Published online 2004 November 8. doi: 10.1073/pnas.0406268101.PMCID: PMC528964 Medical Sciences Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts Hua Su, Shuji Joho, Yu Huang, Alicia Barcena, Janice Arakawa-Hoyt, William Grossman, and Yuet Wai Kan Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16280–16285. Published online 2004 November 8. doi: 10.1073/pnas.0407449101.PMCID: PMC527136 Proteins of purified Epstein-Barr virus Eric Johannsen, Micah Luftig, Michael R. Chase, Steve Weicksel, Ellen Cahir-McFarland, Diego Illanes, David Sarracino, and Elliott Kieff Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16286–16291. Published online 2004 November 8. doi: 10.1073/pnas.0407320101.PMCID: PMC528973 A versatile statistical analysis algorithm to detect genome copy number variation Raoul-Sam Daruwala, Archisman Rudra, Harry Ostrer, Robert Lucito, Michael Wigler, and Bud Mishra Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16292–16297. Published online 2004 November 8. doi: 10.1073/pnas.0407247101.PMCID: PMC528962 The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes Katalin Takács, Camille Du Roure, Stephen Nabarro, Niall Dillon, John H. McVey, Zoe Webster, Angus MacNeil, István Bartók, Christopher Higgins, David Gray, Matthias Merkenschlager, and Amanda G. Fisher Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16298–16303. Published online 2004 November 1. doi: 10.1073/pnas.0405271101.PMCID: PMC528951 Microbiology Uncoupling substrate and activation functions of rotavirus NSP5: Phosphorylation of Ser-67 by casein kinase 1 is essential for hyperphosphorylation Catherine Eichwald, Germaine Jacob, Bartosz Muszynski, Jorge E. Allende, and Oscar R. Burrone Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16304–16309. Published online 2004 November 1. doi: 10.1073/pnas.0406691101.PMCID: PMC528968 From the Cover: Essential role of membrane-attack protein in malarial transmission to mosquito host Kimie Kadota, Tomoko Ishino, Takahiro Matsuyama, Yasuo Chinzei, and Masao Yuda Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16310–16315. Published online 2004 November 1. doi: 10.1073/pnas.0406187101.PMCID: PMC524694 A crucial arginine residue is required for a conformational switch in NifL to regulate nitrogen fixation in Azotobacter vinelandii Isabel Martinez-Argudo, Richard Little, and Ray Dixon Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16316–16321. Published online 2004 November 8. doi: 10.1073/pnas.0405312101.PMCID: PMC528952 Integrated regulatory responses of fimB to N-acetylneuraminic (sialic) acid and GlcNAc in Escherichia coli K-12 Baljinder K. Sohanpal, Sammia El-Labany, Maryam Lahooti, Jacqueline A. Plumbridge, and Ian C. Blomfield Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16322–16327. Published online 2004 November 8. doi: 10.1073/pnas.0405821101.PMCID: PMC526197 Identification of viral genomic elements responsible for rabies virus neuroinvasiveness Milosz Faber, Rojjanaporn Pulmanausahakul, Kazuhiko Nagao, Mikhail Prosniak, Amy B. Rice, Hilary Koprowski, Matthias J. Schnell, and Bernhard Dietzschold Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16328–16332. Published online 2004 November 1. doi: 10.1073/pnas.0407289101.PMCID: PMC528969 Neuroscience Guiding neuronal development with in situ microfabrication Bryan Kaehr, Richard Allen, David J. Javier, John Currie, and Jason B. Shear Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16104–16108. Published online 2004 November 8. doi: 10.1073/pnas.0407204101.PMCID: PMC528953 Fly motion vision is based on Reichardt detectors regardless of the signal-to-noise ratio J. Haag, W. Denk, and A. Borst Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16333–16338. Published online 2004 November 8. doi: 10.1073/pnas.0407368101.PMCID: PMC526200 RGS9-2 modulates D2 dopamine receptor-mediated Ca2+ channel inhibition in rat striatal cholinergic interneurons Theresa M. Cabrera-Vera, Salvador Hernandez, Laurie R. Earls, Martina Medkova, Anna K. Sundgren-Andersson, D. James Surmeier, and Heidi E. Hamm Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16339–16344. Published online 2004 November 8. doi: 10.1073/pnas.0407416101.PMCID: PMC528982 Tissue plasminogen activator promotes the effects of corticotropin-releasing factor on the amygdala and anxiety-like behavior Tomasz Matys, Robert Pawlak, Elzbieta Matys, Constantine Pavlides, Bruce S. McEwen, and Sidney Strickland Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16345–16350. Published online 2004 November 2. doi: 10.1073/pnas.0407355101.PMCID: PMC528975 Associative learning shapes the neural code for stimulus magnitude in primary auditory cortex Daniel B. Polley, Marc A. Heiser, David T. Blake, Christoph E. Schreiner, and Michael M. Merzenich Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16351–16356. Published online 2004 November 8. doi: 10.1073/pnas.0407586101.PMCID: PMC528983 Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice Jinhui Chen, Sanjay S. P. Magavi, and Jeffrey D. Macklis Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16357–16362. Published online 2004 November 8. doi: 10.1073/pnas.0406795101.PMCID: PMC528970 Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease Mercedes Fernandez, Alessandro Giuliani, Stefania Pirondi, Giulia D'Intino, Luciana Giardino, Luigi Aloe, Rita Levi-Montalcini, and Laura Calzà Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16363–16368. Published online 2004 November 8. doi: 10.1073/pnas.0407262101.PMCID: PMC526198 Long-term meditators self-induce high-amplitude gamma synchrony during mental practice Antoine Lutz, Lawrence L. Greischar, Nancy B. Rawlings, Matthieu Ricard, and Richard J. Davidson Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16369–16373. Published online 2004 November 8. doi: 10.1073/pnas.0407401101.PMCID: PMC526201 Physiology Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation Junko Kurokawa, Howard K. Motoike, Jenny Rao, and Robert S. Kass Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16374–16378. Published online 2004 November 4. doi: 10.1073/pnas.0405583101.PMCID: PMC525330 Plant Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: The phytochrome-interacting transcription factor, PIF3, acts early, selectively, and positively in light-induced chloroplast development Elena Monte, James M. Tepperman, Bassem Al-Sady, Karen A. Kaczorowski, Jose M. Alonso, Joseph R. Ecker, Xin Li, Yuelin Zhang, and Peter H. Quail Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16091–16098. Published online 2004 October 25. doi: 10.1073/pnas.0407107101.PMCID: PMC528976 Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE Mary Frank, Coumaran Egile, Julia Dyachok, Stevan Djakovic, Michelle Nolasco, Rong Li, and Laurie G. Smith Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16379–16384. Published online 2004 November 8. doi: 10.1073/pnas.0407392101.PMCID: PMC528980 Social Sciences Economic Sciences Groups of diverse problem solvers can outperform groups of high-ability problem solvers Lu Hong and Scott E. Page Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16385–16389. Published online 2004 November 8. doi: 10.1073/pnas.0403723101.PMCID: PMC528939 Corrections Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16390. doi: 10.1073/pnas.0407231101.PMCID: PMC528956 Corrects: Gonçalo Castelo-Branco, et al. Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a. Proc Natl Acad Sci U S A. 2003 October 28; 100(22): 12747–12752. Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16391. doi: 10.1073/pnas.0407263101.PMCID: PMC528965 Corrects: Isabelle Landrieu, et al. A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2004 September 7; 101(36): 13380–13385. Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16391. doi: 10.1073/pnas.0407377101.PMCID: PMC528979 Corrects: Yuuko Ninomiya, et al. From the Cover: Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining. Proc Natl Acad Sci U S A. 2004 August 17; 101(33): 12248–12253. Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16391. doi: 10.1073/pnas.0407689101.PMCID: PMC528984 Corrects: Ingrid M. Parker. Mating patterns and rates of biological invasion. Proc Natl Acad Sci U S A. 2004 September 21; 101(38): 13695–13696. Proc Natl Acad Sci U S A. 2004 November 16; 101(46): 16391. doi: 10.1073/pnas.0407740101.PMCID: PMC528986 Corrects: Jiunn-Liang Chen, et al. An emerging consensus for telomerase RNA structure. Proc Natl Acad Sci U S A. 2004 October 12; 101(41): 14683–14684. |