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Volume 91(3);  February 1, 1994
The cover of the journal
American origins.
K M Weiss
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 833–835.
PMCID: PMC521405
Atomic force microscopy produces faithful high-resolution images of protein surfaces in an aqueous environment.
S Karrasch, R Hegerl, J H Hoh, W Baumeister, and A Engel
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 836–838.
PMCID: PMC521406
Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.
D Ron, C H Chen, J Caldwell, L Jamieson, E Orr, and D Mochly-Rosen
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 839–843.
PMCID: PMC521407
Identification of active-site residues of the adenovirus endopeptidase.
C Rancourt, K Tihanyi, M Bourbonniere, and J M Weber
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 844–847.
PMCID: PMC521408
Liver fatty acid-binding protein: specific mediator of the mitogenesis induced by two classes of carcinogenic peroxisome proliferators.
S H Khan and S Sorof
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 848–852.
PMCID: PMC521409
Association of a cellular myosin II with anionic phospholipids and the neuronal plasma membrane.
D Li, M Miller, and P D Chantler
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 853–857.
PMCID: PMC521410
Enhancement in amount of P1 (hsp60) in mutants of Chinese hamster ovary (CHO-K1) cells exhibiting increases in the A system of amino acid transport.
M Jones, R S Gupta, and E Englesberg
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 858–862.
PMCID: PMC521411
DNA class organization on maize Adh1 yeast artificial chromosomes.
P S Springer, K J Edwards, and J L Bennetzen
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 863–867.
PMCID: PMC521412
Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C.
X Li and P M Burgers
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 868–872.
PMCID: PMC521413
Oncogene activation of human keratin 18 transcription via the Ras signal transduction pathway.
R Pankov, A Umezawa, R Maki, C J Der, C A Hauser, and R G Oshima
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 873–877.
PMCID: PMC521414
Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons.
H Schweitz, C Heurteaux, P Bois, D Moinier, G Romey, and M Lazdunski
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 878–882.
PMCID: PMC521415
Chimeric restriction endonuclease.
Y G Kim and S Chandrasegaran
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 883–887.
PMCID: PMC521416
Molecular model of the specificity pocket of the hepatitis C virus protease: implications for substrate recognition.
E Pizzi, A Tramontano, L Tomei, N La Monica, C Failla, M Sardana, T Wood, and R De Francesco
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 888–892.
PMCID: PMC521417
A simpler sort of antibody.
L Masat, M Wabl, and J P Johnson
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 893–896.
PMCID: PMC521418
Analysis of a hyperdeformed band of 152(66)Dy86 on the basis of a structure with two revolving clusters, each with a previously unrecognized two-tiered structure.
L Pauling
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 897–899.
PMCID: PMC521419
Identification of a vitamin D-response element in the rat calcidiol (25-hydroxyvitamin D3) 24-hydroxylase gene.
C Zierold, H M Darwish, and H F DeLuca
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 900–902.
PMCID: PMC521420
Splicing function of mammalian U6 small nuclear RNA: conserved positions in central domain and helix I are essential during the first and second step of pre-mRNA splicing.
T Wolff, R Menssen, J Hammel, and A Bindereif
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 903–907.
PMCID: PMC521421
Evidence for a non-alpha-helical DNA-binding motif in the Rel homology region.
J Liu, M Sodeoka, W S Lane, and G L Verdine
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 908–912.
PMCID: PMC521422
Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.
C Hammond, I Braakman, and A Helenius
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 913–917.
PMCID: PMC521423
Phylogenetic analysis of RNA editing: a primitive genetic phenomenon.
L F Landweber and W Gilbert
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 918–921.
PMCID: PMC521424
Candida albicans estrogen-binding protein gene encodes an oxidoreductase that is inhibited by estradiol.
N D Madani, P J Malloy, P Rodriguez-Pombo, A V Krishnan, and D Feldman
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 922–926.
PMCID: PMC521425
Arabidopsis thaliana contains two differentially expressed 3-hydroxy-3-methylglutaryl-CoA reductase genes, which encode microsomal forms of the enzyme.
M Enjuto, L Balcells, N Campos, C Caelles, M Arró, and A Boronat
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 927–931.
PMCID: PMC521426
Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.
A Sureau and B Perbal
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 932–936.
PMCID: PMC521427
Determination of spin-label orientation within the myosin head.
P G Fajer
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 937–941.
PMCID: PMC521428
A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif.
T G Doak, F P Doerder, C L Jahn, and G Herrick
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 942–946.
PMCID: PMC521429
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.
C Pothoulakis, I Castagliuolo, J T LaMont, A Jaffer, J C O'Keane, R M Snider, and S E Leeman
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 947–951.
PMCID: PMC521430
The protein phosphatase inhibitor calyculin A mimics elicitor action in plant cells and induces rapid hyperphosphorylation of specific proteins as revealed by pulse labeling with [33P]phosphate.
G Felix, M Regenass, P Spanu, and T Boller
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 952–956.
PMCID: PMC521431
Cytoplasmic sequences of the growth hormone receptor necessary for signal transduction.
L Goujon, G Allevato, G Simonin, L Paquereau, A Le Cam, J Clark, J H Nielsen, J Djiane, M C Postel-Vinay, M Edery, et al.
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 957–961.
PMCID: PMC521432
Convergence of quantum electrodynamics in a curved modification of Minkowski space.
I E Segal and Z Zhou
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 962–963.
PMCID: PMC521433
Supramolecular organization of the mammalian translation system.
B S Negrutskii, R Stapulionis, and M P Deutscher
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 964–968.
PMCID: PMC521434
Humanization of murine monoclonal antibodies through variable domain resurfacing.
M A Roguska, J T Pedersen, C A Keddy, A H Henry, S J Searle, J M Lambert, V S Goldmacher, W A Blättler, A R Rees, and B C Guild
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 969–973.
PMCID: PMC521435
Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.
C Portera-Cailliau, C H Sung, J Nathans, and R Adler
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 974–978.
PMCID: PMC521436
Multiple forms of poly(A) polymerases in human cells.
A C Thuresson, J Aström, A Aström, K O Grönvik, and A Virtanen
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 979–983.
PMCID: PMC521437
Light-regulated, tissue-specific immunophilins in a higher plant.
S Luan, M W Albers, and S L Schreiber
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 984–988.
PMCID: PMC521438
High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains.
H G Cheon, W J LaRochelle, D P Bottaro, W H Burgess, and S A Aaronson
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 989–993.
PMCID: PMC521439
Concerted evolution at the population level: pupfish HindIII satellite DNA sequences.
J F Elder, Jr and B J Turner
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 994–998.
PMCID: PMC521440
Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide.
I P Oswald, I Eltoum, T A Wynn, B Schwartz, P Caspar, D Paulin, A Sher, and S L James
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 999–1003.
PMCID: PMC521441
Identification of the MAGE-1 gene product by monoclonal and polyclonal antibodies.
Y T Chen, E Stockert, Y Chen, P Garin-Chesa, W J Rettig, P van der Bruggen, T Boon, and L J Old
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1004–1008.
PMCID: PMC521442
Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors.
H Liu, J L Brown, L Jasmin, J E Maggio, S R Vigna, P W Mantyh, and A I Basbaum
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1009–1013.
PMCID: PMC521443
Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels.
J Nakai, B A Adams, K Imoto, and K G Beam
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1014–1018.
PMCID: PMC521444
Effect of ethanol on cytochrome P450 in the rat brain.
M Warner and J A Gustafsson
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1019–1023.
PMCID: PMC521445
All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase.
M K Dosanjh, A Chenna, E Kim, H Fraenkel-Conrat, L Samson, and B Singer
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1024–1028.
PMCID: PMC521446
Spectral hole burning and selection of conformational substates in chromoproteins.
J Friedrich, J Gafert, J Zollfrank, J Vanderkooi, and J Fidy
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1029–1033.
PMCID: PMC521447
Mechanism of electron transfer in the cytochrome b/f complex of algae: evidence for a semiquinone cycle.
P Joliot and A Joliot
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1034–1038.
PMCID: PMC521448
Cellular epigenetics: control of the size, shape, and spatial distribution of transformed foci by interactions between the transformed and nontransformed cells.
H Rubin
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1039–1043.
PMCID: PMC521449
Superoxide and peroxynitrite in atherosclerosis.
C R White, T A Brock, L Y Chang, J Crapo, P Briscoe, D Ku, W A Bradley, S H Gianturco, J Gore, B A Freeman, et al.
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1044–1048.
PMCID: PMC521450
Assessment of genetic diversity of seagrass populations using DNA fingerprinting: implications for population stability and management.
R S Alberte, G K Suba, G Procaccini, R C Zimmerman, and S R Fain
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1049–1053.
PMCID: PMC521451
An analogue of the DnaJ molecular chaperone in Escherichia coli.
C Ueguchi, M Kakeda, H Yamada, and T Mizuno
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1054–1058.
PMCID: PMC521452
Hidden Markov models of biological primary sequence information.
P Baldi, Y Chauvin, T Hunkapiller, and M A McClure
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1059–1063.
PMCID: PMC521453
Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.
D Meyer and C Birchmeier
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1064–1068.
PMCID: PMC521454
Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes.
T Nakano, E W Raines, J A Abraham, M Klagsbrun, and R Ross
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1069–1073.
PMCID: PMC521455
Keratinocyte growth factor functions in epithelial induction during seminal vesicle development.
E T Alarid, J S Rubin, P Young, M Chedid, D Ron, S A Aaronson, and G R Cunha
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1074–1078.
PMCID: PMC521456
Evolution of recombination among multiple selected loci: a generalized reduction principle.
L A Zhivotovsky, M W Feldman, and F B Christiansen
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1079–1083.
PMCID: PMC521457
Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.
A De, D G Brown, M A Gorman, M Carr, M R Sanderson, and P S Freemont
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1084–1088.
PMCID: PMC521458
Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
T N Bhat, G A Bentley, G Boulot, M I Greene, D Tello, W Dall'Acqua, H Souchon, F P Schwarz, R A Mariuzza, and R J Poljak
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1089–1093.
PMCID: PMC521459
Identification of T-cell receptor alpha-chain genes in the chicken.
T W Göbel, C L Chen, J Lahti, T Kubota, C L Kuo, R Aebersold, L Hood, and M D Cooper
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1094–1098.
PMCID: PMC521460
CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency.
M Farrington, L S Grosmaire, S Nonoyama, S H Fischer, D Hollenbaugh, J A Ledbetter, R J Noelle, A Aruffo, and H D Ochs
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1099–1103.
PMCID: PMC521461
Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytes.
K Saksela, C Stevens, P Rubinstein, and D Baltimore
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1104–1108.
PMCID: PMC521462
A single negative charge within the pore region of a cGMP-gated channel controls rectification, Ca2+ blockage, and ionic selectivity.
E Eismann, F Müller, S H Heinemann, and U B Kaupp
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1109–1113.
PMCID: PMC521463
Stimulation of endogenous ADP-ribosylation by brefeldin A.
M A De Matteis, M Di Girolamo, A Colanzi, M Pallas, G Di Tullio, L J McDonald, J Moss, G Santini, S Bannykh, D Corda, et al.
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1114–1118.
PMCID: PMC521464
Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor.
D P Gearing, S F Ziegler, M R Comeau, D Friend, B Thoma, D Cosman, L Park, and B Mosley
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1119–1123.
PMCID: PMC521465
Phylogenetic subtypes of human T-lymphotropic virus type I and their relations to the anthropological background.
T Miura, T Fukunaga, T Igarashi, M Yamashita, E Ido, S Funahashi, T Ishida, K Washio, S Ueda, K Hashimoto, et al.
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1124–1127.
PMCID: PMC521466
Intracellular pH and the control of multidrug resistance.
S Simon, D Roy, and M Schindler
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1128–1132.
PMCID: PMC521467
Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.
J J Wysolmerski, A E Broadus, J Zhou, E Fuchs, L M Milstone, and W M Philbrick
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1133–1137.
PMCID: PMC521468
Exogenous Mtv-7 superantigen transgene expression in major histocompatibility complex class II I-E- mice reconstituted with embryonic stem cell-derived hematopoietic stem cells.
C A Chambers, J Kang, J Pawling, B Huber, N Hozumi, and A Nagy
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1138–1142.
PMCID: PMC521469
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine.
A F Cowman, D Galatis, and J K Thompson
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1143–1147.
PMCID: PMC521470
Asynchronous pre- and postsynaptic activity induces associative long-term depression in area CA1 of the rat hippocampus in vitro.
D Debanne, B H Gähwiler, and S M Thompson
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1148–1152.
PMCID: PMC521471
Intra- and extracellular calcium modulates stereocilia stiffness on chick cochlear hair cells.
S S Pae and J C Saunders
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1153–1157.
PMCID: PMC521472
Mitochondrial DNA "clock" for the Amerinds and its implications for timing their entry into North America.
A Torroni, J V Neel, R Barrantes, T G Schurr, and D C Wallace
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1158–1162.
PMCID: PMC521473
Autophosphorylation and phosphotransfer in the Bordetella pertussis BvgAS signal transduction cascade.
M A Uhl and J F Miller
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1163–1167.
PMCID: PMC521474
A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family.
M van Zeijl, S V Johann, E Closs, J Cunningham, R Eddy, T B Shows, and B O'Hara
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1168–1172.
PMCID: PMC521475
DNA double-strand break repair: genetic determinants of flanking crossing-over.
K Kusano, Y Sunohara, N Takahashi, H Yoshikura, and I Kobayashi
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1173–1177.
PMCID: PMC521476
PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.
Z Chen, F Guidez, P Rousselot, A Agadir, S J Chen, Z Y Wang, L Degos, A Zelent, S Waxman, and C Chomienne
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1178–1182.
PMCID: PMC521477
Oxidative susceptibility of low density lipoprotein subfractions is related to their ubiquinol-10 and alpha-tocopherol content.
D L Tribble, J J van den Berg, P A Motchnik, B N Ames, D M Lewis, A Chait, and R M Krauss
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1183–1187.
PMCID: PMC521478
A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization.
J L Corey, M W Quick, N Davidson, H A Lester, and J Guastella
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1188–1192.
PMCID: PMC521479
Corrections
Expression of functional trk protooncogene in human monocytes
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1193.
PMCID: PMC521480
Corrects: P B Ehrhard, et al. Expression of functional trk protooncogene in human monocytes. Proc Natl Acad Sci U S A. 1993 June 15; 90(12): 5423–5427.
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization.
B L Kieffer, K Befort, C Gavériaux-Ruff, and C G Hirth
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1193.
PMCID: PMC521481
Corrects: B L Kieffer, et al. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc Natl Acad Sci U S A. 1992 December 15; 89(24): 12048–12052.
Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries
Proc Natl Acad Sci U S A. 1994 February 1; 91(3): 1193.
PMCID: PMC521482
Corrects: R A Williamson, et al. Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries. Proc Natl Acad Sci U S A. 1993 May 1; 90(9): 4141–4145.
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