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Volume 36(16);  September 2008
Gene regulation, Chromatin and Epigenetics
An intronic microRNA silences genes that are functionally antagonistic to its host gene
Sailen Barik
Nucleic Acids Res. 2008 September; 36(16): 5232–5241. Published online 2008 September. doi: 10.1093/nar/gkn513.
PMCID: PMC2532712
The orphan receptor ERRα interferes with steroid signaling
Catherine Teyssier, Stéphanie Bianco, Olivia Lanvin, and Jean-Marc Vanacker
Nucleic Acids Res. 2008 September; 36(16): 5350–5361. Published online 2008 September. doi: 10.1093/nar/gkn520.
PMCID: PMC2532727
Genome Integrity, Repair and Replication
The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ
Nives Selak, Csanád Z. Bachrati, Igor Shevelev, Tobias Dietschy, Barbara van Loon, Anette Jacob, Ulrich Hübscher, Joerg D. Hoheisel, Ian D. Hickson, and Igor Stagljar
Nucleic Acids Res. 2008 September; 36(16): 5166–5179. Published online 2008 September. doi: 10.1093/nar/gkn498.
PMCID: PMC2532730
Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
Anja Restle, Martin Färber, Cindy Baumann, Michael Böhringer, Karl Heinz Scheidtmann, Carsten Müller-Tidow, and Lisa Wiesmüller
Nucleic Acids Res. 2008 September; 36(16): 5362–5375. Published online 2008 September. doi: 10.1093/nar/gkn503.
PMCID: PMC2532731
Molecular Biology
Molecular interactions of ASPP1 and ASPP2 with the p53 protein family and the apoptotic promoters PUMA and Bax
Seema Patel, Roger George, Flavia Autore, Franca Fraternali, John E. Ladbury, and Penka V. Nikolova
Nucleic Acids Res. 2008 September; 36(16): 5139–5151. Published online 2008 September. doi: 10.1093/nar/gkn490.
PMCID: PMC2532732
A member of the Whirly family is a multifunctional RNA- and DNA-binding protein that is essential for chloroplast biogenesis
Jana Prikryl, Kenneth P. Watkins, Giulia Friso, Klaas J. van Wijk, and Alice Barkan
Nucleic Acids Res. 2008 September; 36(16): 5152–5165. Published online 2008 September. doi: 10.1093/nar/gkn492.
PMCID: PMC2532728
Positive roles of SAS2 in DNA replication and transcriptional silencing in yeast
Yanfei Zou and Xin Bi
Nucleic Acids Res. 2008 September; 36(16): 5189–5200. Published online 2008 September. doi: 10.1093/nar/gkn465.
PMCID: PMC2532737
Formation of an RNA polymerase II preinitiation complex on an RNA promoter derived from the hepatitis delta virus RNA genome
Abrahem Abrahem and Martin Pelchat
Nucleic Acids Res. 2008 September; 36(16): 5201–5211. Published online 2008 September. doi: 10.1093/nar/gkn501.
PMCID: PMC2532721
The RecU Holliday junction resolvase acts at early stages of homologous recombination
Cristina Cañas, Begoña Carrasco, Silvia Ayora, and Juan C. Alonso
Nucleic Acids Res. 2008 September; 36(16): 5242–5249. Published online 2008 September. doi: 10.1093/nar/gkn500.
PMCID: PMC2532717
A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress
Junko Kimura, Su Tien Nguyen, Hanshao Liu, Naoe Taira, Yoshio Miki, and Kiyotsugu Yoshida
Nucleic Acids Res. 2008 September; 36(16): 5250–5259. Published online 2008 September. doi: 10.1093/nar/gkn506.
PMCID: PMC2532742
Stringent promoter recognition and autoregulation by the group 3 σ-factor SigF in the cyanobacterium Synechocystis sp. strain PCC 6803
Munehiko Asayama and Sousuke Imamura
Nucleic Acids Res. 2008 September; 36(16): 5297–5305. Published online 2008 September. doi: 10.1093/nar/gkn453.
PMCID: PMC2532724
Intragenic suppressors of temperature-sensitive rne mutations lead to the dissociation of RNase E activity on mRNA and tRNA substrates in Escherichia coli
Tariq Perwez, Danyal Hami, Valerie F. Maples, Zhao Min, Bi-Cheng Wang, and Sidney R. Kushner
Nucleic Acids Res. 2008 September; 36(16): 5306–5318. Published online 2008 September. doi: 10.1093/nar/gkn476.
PMCID: PMC2532720
N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis
Na Liu, Lifeng Wang, Xia Li, Qi Yang, Xinping Liu, Jing Zhang, Jian Zhang, Yousheng Wu, Shaoping Ji, Yingqi Zhang, Angang Yang, Hua Han, and Libo Yao
Nucleic Acids Res. 2008 September; 36(16): 5335–5349. Published online 2008 September. doi: 10.1093/nar/gkn504.
PMCID: PMC2532733
RNA
Frequency and fate of microRNA editing in human brain
Yukio Kawahara, Molly Megraw, Edward Kreider, Hisashi Iizasa, Louis Valente, Artemis G. Hatzigeorgiou, and Kazuko Nishikura
Nucleic Acids Res. 2008 September; 36(16): 5270–5280. Published online 2008 September. doi: 10.1093/nar/gkn479.
PMCID: PMC2532740
Tetrahymena thermophila and Candida albicans Group I intron-derived ribozymes can catalyze the trans-excision-splicing reaction
P. Patrick Dotson, II, Ashley K. Johnson, and Stephen M. Testa
Nucleic Acids Res. 2008 September; 36(16): 5281–5289. Published online 2008 September. doi: 10.1093/nar/gkn507.
PMCID: PMC2532722
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets
María Flor García-Mayoral, Irene Díaz-Moreno, David Hollingworth, and Andres Ramos
Nucleic Acids Res. 2008 September; 36(16): 5290–5296. Published online 2008 September. doi: 10.1093/nar/gkn509.
PMCID: PMC2532734
miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
Qin Liu, Hanjiang Fu, Fang Sun, Haoming Zhang, Yi Tie, Jie Zhu, Ruiyun Xing, Zhixian Sun, and Xiaofei Zheng
Nucleic Acids Res. 2008 September; 36(16): 5391–5404. Published online 2008 September. doi: 10.1093/nar/gkn522.
PMCID: PMC2532718
Structural Biology
The structure of SgrAI bound to DNA; recognition of an 8 base pair target
Pete W. Dunten, Elizabeth J. Little, Mark T. Gregory, Veena M. Manohar, Michael Dalton, David Hough, Jurate Bitinaite, and Nancy C. Horton
Nucleic Acids Res. 2008 September; 36(16): 5405–5416. Published online 2008 September. doi: 10.1093/nar/gkn510.
PMCID: PMC2532715
Survey and Summary
The triple helix: 50 years later, the outcome
Maria Duca, Pierre Vekhoff, Kahina Oussedik, Ludovic Halby, and Paola B. Arimondo
Nucleic Acids Res. 2008 September; 36(16): 5123–5138. Published online 2008 September. doi: 10.1093/nar/gkn493.
PMCID: PMC2532714
Genomics
A comparison of random sequence reads versus 16S rDNA sequences for estimating the biodiversity of a metagenomic library
Chaysavanh Manichanh, Charles E. Chapple, Lionel Frangeul, Karine Gloux, Roderic Guigo, and Joel Dore
Nucleic Acids Res. 2008 September; 36(16): 5180–5188. Published online 2008 September. doi: 10.1093/nar/gkn496.
PMCID: PMC2532719
Methods Online
Specific ligation to double-stranded RNA for analysis of cellular RNA::RNA interactions
Omid R. Faridani, Gerald M. McInerney, Katarina Gradin, and Liam Good
Nucleic Acids Res. 2008 September; 36(16): e99. Published online 2008 September. doi: 10.1093/nar/gkn445.
PMCID: PMC2532711
Detection of Adriamycin–DNA adducts by accelerator mass spectrometry at clinically relevant Adriamycin concentrations
Kate E. Coldwell, Suzanne M. Cutts, Ted J. Ognibene, Paul T. Henderson, and Don R. Phillips
Nucleic Acids Res. 2008 September; 36(16): e100. Published online 2008 September. doi: 10.1093/nar/gkn439.
PMCID: PMC2532723
Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch
David Greber, Marie Daoud El-Baba, and Martin Fussenegger
Nucleic Acids Res. 2008 September; 36(16): e101. Published online 2008 September. doi: 10.1093/nar/gkn443.
PMCID: PMC2532736
Phenotypic engineering by reprogramming gene transcription using novel artificial transcription factors in Escherichia coli
Ju Young Lee, Bong Hyun Sung, Byung Jo Yu, Jun Hyoung Lee, Sang Hee Lee, Mi Sun Kim, Michael D. Koob, and Sun Chang Kim
Nucleic Acids Res. 2008 September; 36(16): e102. Published online 2008 September. doi: 10.1093/nar/gkn449.
PMCID: PMC2532725
Transduction of artificial transcriptional regulatory proteins into human cells
Chae-Ok Yun, Hyun-Chul Shin, Tae-Dong Kim, Wan-Hee Yoon, Yoon-A Kang, Heung-Sun Kwon, Seong Keun Kim, and Jin-Soo Kim
Nucleic Acids Res. 2008 September; 36(16): e103. Published online 2008 September. doi: 10.1093/nar/gkn398.
PMCID: PMC2532713
End-joining long nucleic acid polymers
M. van den Hout, S. Hage, C. Dekker, and N. H. Dekker
Nucleic Acids Res. 2008 September; 36(16): e104. Published online 2008 September. doi: 10.1093/nar/gkn442.
PMCID: PMC2532729
Substantial biases in ultra-short read data sets from high-throughput DNA sequencing
Juliane C. Dohm, Claudio Lottaz, Tatiana Borodina, and Heinz Himmelbauer
Nucleic Acids Res. 2008 September; 36(16): e105. Published online 2008 September. doi: 10.1093/nar/gkn425.
PMCID: PMC2532726
Computational Biology
Genome-wide identification of in vivo protein–DNA binding sites from ChIP-Seq data
Raja Jothi, Suresh Cuddapah, Artem Barski, Kairong Cui, and Keji Zhao
Nucleic Acids Res. 2008 September; 36(16): 5221–5231. Published online 2008 September. doi: 10.1093/nar/gkn488.
PMCID: PMC2532738
The cis-regulatory map of Shewanella genomes
Jiajian Liu, Xing Xu, and Gary D. Stormo
Nucleic Acids Res. 2008 September; 36(16): 5376–5390. Published online 2008 September. doi: 10.1093/nar/gkn515.
PMCID: PMC2532739
Nucleic Acid Enzymes
A comparative analysis of two conserved motifs in bacterial poly(A) polymerase and CCA-adding enzyme
Andrea Just, Falk Butter, Michelle Trenkmann, Tony Heitkam, Mario Mörl, and Heike Betat
Nucleic Acids Res. 2008 September; 36(16): 5212–5220. Published online 2008 September. doi: 10.1093/nar/gkn494.
PMCID: PMC2532741
Hyperthermophilic Aquifex aeolicus initiates primer synthesis on a limited set of trinucleotides comprised of cytosines and guanines
Marilynn A. Larson, Rafael Bressani, Khalid Sayood, Jacob E. Corn, James M. Berger, Mark A. Griep, and Steven H. Hinrichs
Nucleic Acids Res. 2008 September; 36(16): 5260–5269. Published online 2008 September. doi: 10.1093/nar/gkn461.
PMCID: PMC2532735
Interactions between branched DNAs and peptide inhibitors of DNA repair
Kevin V. Kepple, Namita Patel, Peter Salamon, and Anca M. Segall
Nucleic Acids Res. 2008 September; 36(16): 5319–5334. Published online 2008 September. doi: 10.1093/nar/gkn512.
PMCID: PMC2532710
DNA base flipping by both members of the PspGI restriction–modification system
Michael A. Carpenter and Ashok S. Bhagwat
Nucleic Acids Res. 2008 September; 36(16): 5417–5425. Published online 2008 September. doi: 10.1093/nar/gkn528.
PMCID: PMC2532716
Corrigendum
Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon
Takuma Gondai, Kazuya Yamaguchi, Naoko Miyano-Kurosaki, Yuichirou Habu, and Hiroshi Takaku
Nucleic Acids Res. 2008 September; 36(16): 5426. Published online 2008 September. doi: 10.1093/nar/gkn547.
PMCID: PMC2532709
Corrects: Takuma Gondai, et al. Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon. Nucleic Acids Res. 2008 September; 36(16): 5426.
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