| | This journal provides immediate access to some articles. Commentaries The complexity of mass extinction Hermann W. Pfefferkorn PMCID: PMC516470 MAPping innate immunity John A. T. Young and Andrew Dillin PMCID: PMC516471 Review Multiple pathways process stalled replication forks Bénédicte Michel, Gianfranco Grompone, Maria-Jose Florès, and Vladimir Bidnenko PMCID: PMC516472 Physical Sciences Applied Physical Sciences From the Cover:
Protein patterns at lipid bilayer junctions Raghuveer Parthasarathy and Jay T. Groves PMCID: PMC516475 Observation of force-detected nuclear magnetic resonance in a homogeneous field L. A. Madsen, G. M. Leskowitz, and D. P. Weitekamp PMCID: PMC516476 Chemistry Chemical cytometry on a picoliter-scale integrated microfluidic chip Hongkai Wu, Aaron Wheeler, and Richard N. Zare PMCID: PMC516477 Engineering Sequential shape-and-solder-directed self-assembly of functional microsystems Wei Zheng, Philippe Buhlmann, and Heiko O. Jacobs PMCID: PMC516478 Geology H2-rich fluids from serpentinization: Geochemical and biotic implications N. H. Sleep, A. Meibom, Th. Fridriksson, R. G. Coleman, and D. K. Bird PMCID: PMC516479 Biological Sciences Anthropology Detecting interregionally diversifying natural selection on modern human cranial form by using matched molecular and morphometric data Charles C. Roseman PMCID: PMC516480 Applied Biological Sciences Biosynthesis of artificial microperoxidases by exploiting the secretion and cytochrome c maturation apparatuses of Escherichia coli Martin Braun and Linda Thöny-Meyer PMCID: PMC516481 Biochemistry NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor Christy R. R. Grace, Marilyn H. Perrin, Michael R. DiGruccio, Charleen L. Miller, Jean E. Rivier, Wylie W. Vale, and Roland Riek PMCID: PMC516482 pH-dependent transition between delocalized and trapped valence states of a CuA center and its possible role in proton-coupled electron transfer Hee Jung Hwang and Yi Lu PMCID: PMC516483 From the Cover:
Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase Bradley A. Carlson, Xue-Ming Xu, Gregory V. Kryukov, Mahadev Rao, Marla J. Berry, Vadim N. Gladyshev, and Dolph L. Hatfield PMCID: PMC516484 Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases Patricia Pellicena, David S. Karow, Elizabeth M. Boon, Michael A. Marletta, and John Kuriyan PMCID: PMC516465 An enzymatic molten globule: Efficient coupling of folding and catalysis Katherina Vamvaca, Beat Vögeli, Peter Kast, Konstantin Pervushin, and Donald Hilvert PMCID: PMC516485 Multiple ATP-hydrolyzing sites that potentially function in cytoplasmic dynein Yoshinori Takahashi, Masaki Edamatsu, and Yoko Y. Toyoshima PMCID: PMC516486 Crystal structure of the S-adenosylmethionine-dependent enzyme MoaA and its implications for molybdenum cofactor deficiency in humans Petra Hänzelmann and Hermann Schindelin PMCID: PMC516487 Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1α,25(OH)2-vitamin D3 signaling Mathew T. Mizwicki, Don Keidel, Craig M. Bula, June E. Bishop, Laura P. Zanello, Jean-Marie Wurtz, Dino Moras, and Anthony W. Norman PMCID: PMC516488 Biophysics Simultaneous atomic force microscope and fluorescence measurements of protein unfolding using a calibrated evanescent wave Atom Sarkar, Ragan B. Robertson, and Julio M. Fernandez PMCID: PMC516489 Imaging of single-molecule translocation through nuclear pore complexes Weidong Yang, Jeff Gelles, and Siegfried M. Musser PMCID: PMC516490 From the Cover:
tRNA dynamics on the ribosome during translation Scott C. Blanchard, Harold D. Kim, Ruben L. Gonzalez, Jr., Joseph D. Puglisi, and Steven Chu PMCID: PMC516491 Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets Jonathan V. Rocheleau, Glenn M. Walker, W. Steven Head, Owen P. McGuinness, and David W. Piston PMCID: PMC516492 Repriming the actomyosin crossbridge cycle Walter Steffen and John Sleep PMCID: PMC516493 Tau induces cooperative Taxol binding to microtubules Jennifer L. Ross, Christian D. Santangelo, Victoria Makrides, and D. Kuchnir Fygenson PMCID: PMC516494 Kinetic control of dimer structure formation in amyloid fibrillogenesis Wonmuk Hwang, Shuguang Zhang, Roger D. Kamm, and Martin Karplus PMCID: PMC516495 Cell Biology Deletion of the Ca2+-activated potassium (BK) α-subunit but not the BKβ1-subunit leads to progressive hearing loss Lukas Rüttiger, Matthias Sausbier, Ulrike Zimmermann, Harald Winter, Claudia Braig, Jutta Engel, Martina Knirsch, Claudia Arntz, Patricia Langer, Bernhard Hirt, Marcus Müller, Iris Köpschall, Markus Pfister, Stefan Münkner, Karin Rohbock, Imke Pfaff, Alfons Rüsch, Peter Ruth, and Marlies Knipper PMCID: PMC516466 Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes Ying Zou, Sergei M. Gryaznov, Jerry W. Shay, Woodring E. Wright, and Michael N. Cornforth PMCID: PMC516496 Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro Irina L. Derkatch, Susan M. Uptain, Tiago F. Outeiro, Rajaraman Krishnan, Susan L. Lindquist, and Susan W. Liebman PMCID: PMC516497 Switching leukemia cell phenotype between life and death Steven J. Tucker, Colin Rae, Alison F. Littlejohn, Andrew Paul, and David J. MacEwan PMCID: PMC516498 Developmental Biology Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis Zhibing Zhang, Igor Kostetskii, Stuart B. Moss, Brian H. Jones, Clement Ho, Hongbin Wang, Tatsuro Kishida, George L. Gerton, Glenn L. Radice, and Jerome F. Strauss, III PMCID: PMC516499 Ecology From the Cover:
Environmental mutagenesis during the end-Permian ecological crisis Henk Visscher, Cindy V. Looy, Margaret E. Collinson, Henk Brinkhuis, Johanna H. A. van Konijnenburg-van Cittert, Wolfram M. Kürschner, and Mark A. Sephton PMCID: PMC516500 Evolution H2-rich fluids from serpentinization: Geochemical and biotic implications N. H. Sleep, A. Meibom, Th. Fridriksson, R. G. Coleman, and D. K. Bird PMCID: PMC516479 Modeling the site-specific variation of selection patterns along lineages Stéphane Guindon, Allen G. Rodrigo, Kelly A. Dyer, and John P. Huelsenbeck PMCID: PMC516501 Lack of phylogeography in European mammals before the last glaciation Michael Hofreiter, David Serre, Nadin Rohland, Gernot Rabeder, Doris Nagel, Nicholas Conard, Susanne Münzel, and Svante Pääbo PMCID: PMC516467 Genetics INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of Nancy Hopkins Christen Brownlee PMCID: PMC516473 INAUGURAL ARTICLE by a Recently Elected Academy Member: Identification of 315 genes essential for early zebrafish development Adam Amsterdam, Robert M. Nissen, Zhaoxia Sun, Eric C. Swindell, Sarah Farrington, and Nancy Hopkins PMCID: PMC516474 The immune regulatory protein B7-H3 promotes osteoblast differentiation and bone mineralization W.-K. Suh, S. X. Wang, A. H. Jheon, L. Moreno, S. K. Yoshinaga, B. Ganss, J. Sodek, M. D. Grynpas, and T. W. Mak PMCID: PMC516502 Drosophila lifespan enhancement by exogenous bacteria Ted Brummel, Alisa Ching, Laurent Seroude, Anne F. Simon, and Seymour Benzer PMCID: PMC516503 An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster Johannes H. Bauer, Stephan Goupil, Graham B. Garber, and Stephen L. Helfand PMCID: PMC516504 Orthogonal analysis of C/EBPβ targets in vivo during liver proliferation Joshua R. Friedman, Brian Larris, Phillip P. Le, T. Harshani Peiris, Athanasios Arsenlis, Jonathan Schug, John W. Tobias, Klaus H. Kaestner, and Linda E. Greenbaum PMCID: PMC516505 Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality Gijs van Haaften, Nadine L. Vastenhouw, Ellen A. A. Nollen, Ronald H. A. Plasterk, and Marcel Tijsterman PMCID: PMC516506 Immunology Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled Hong Ming Shen and Ursula Storb PMCID: PMC516507 De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination Nasim A. Begum, Kazuo Kinoshita, Masamichi Muramatsu, Hitoshi Nagaoka, Reiko Shinkura, and Tasuku Honjo PMCID: PMC516508 Medical Sciences Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects Karlyne M. Reilly, Robert G. Tuskan, Emily Christy, Dagan A. Loisel, Jeremy Ledger, Roderick T. Bronson, C. Dahlem Smith, Shirley Tsang, David J. Munroe, and Tyler Jacks PMCID: PMC516509 Decreased neointimal formation in Nox2-deficient mice reveals a direct role for NADPH oxidase in the response to arterial injury Zhiping Chen, John F. Keaney, Jr., Eberhard Schulz, Bruce Levison, Lian Shan, Masashi Sakuma, Xiaobin Zhang, Can Shi, Stanley L. Hazen, and Daniel I. Simon PMCID: PMC516510 Polymorphisms of cardiac presynaptic α2C adrenergic receptors: Diverse intragenic variability with haplotype-specific functional effects Kersten M. Small, Jeanne Mialet-Perez, Carrie A. Seman, Cheryl T. Theiss, Kari M. Brown, and Stephen B. Liggett PMCID: PMC516511 Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein Silvija I. Staprans, Ashley P. Barry, Guido Silvestri, Jeffrey T. Safrit, Natalia Kozyr, Beth Sumpter, Hanh Nguyen, Harold McClure, David Montefiori, Jeffrey I. Cohen, and Mark B. Feinberg PMCID: PMC516468 The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport Constanze Bergt, Subramaniam Pennathur, Xiaoyun Fu, Jaeman Byun, Kevin O'Brien, Thomas O. McDonald, Pragya Singh, G. M. Anantharamaiah, Alan Chait, John Brunzell, Randolph L. Geary, John F. Oram, and Jay W. Heinecke PMCID: PMC516512 Microbiology Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication Matthew J. Evans, Charles M. Rice, and Stephen P. Goff PMCID: PMC516513 Feline immunodeficiency virus targets activated CD4+ T cells by using CD134 as a binding receptor Aymeric de Parseval, Udayan Chatterji, Peiqing Sun, and John H. Elder PMCID: PMC516514 Neuroscience Modulation of long-range neural synchrony reflects temporal limitations of visual attention in humans Joachim Gross, Frank Schmitz, Irmtraud Schnitzler, Klaus Kessler, Kimron Shapiro, Bernhard Hommel, and Alfons Schnitzler PMCID: PMC516515 A nonsense mutation in the gene encoding a zebrafish myosin VI isoform causes defects in hair-cell mechanotransduction James A. Kappler, Catherine J. Starr, Dylan K. Chan, Richard Kollmar, and A. J. Hudspeth PMCID: PMC516516 Physiology RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR) Dawei Jiang, Bailong Xiao, Dongmei Yang, Ruiwu Wang, Philip Choi, Lin Zhang, Heping Cheng, and S. R. Wayne Chen PMCID: PMC516517 Mechanosensory function of microvilli of the kidney proximal tubule Zhaopeng Du, Yi Duan, QingShang Yan, Alan M. Weinstein, Sheldon Weinbaum, and Tong Wang PMCID: PMC516518 Oxytocin in cardiac ontogeny Marek Jankowski, Bogdan Danalache, Donghao Wang, Pangala Bhat, Fadi Hajjar, Mieczyslaw Marcinkiewicz, Joanne Paquin, Samuel M. McCann, and Jolanta Gutkowska PMCID: PMC516519 Plant Biology Most of ADP·glucose linked to starch biosynthesis occurs outside the chloroplast in source leaves Edurne Baroja-Fernández, Francisco José Muñoz, Aitor Zandueta-Criado, María Teresa Morán-Zorzano, Alejandro Miguel Viale, Nora Alonso-Casajús, and Javier Pozueta-Romero PMCID: PMC516520 Psychology The time course of visual information accrual guiding eye movement decisions Avi Caspi, Brent R. Beutter, and Miguel P. Eckstein PMCID: PMC516521 From the Cover:
Aging reduces neural specialization in ventral visual cortex Denise C. Park, Thad A. Polk, Rob Park, Meredith Minear, Anna Savage, and Mason R. Smith PMCID: PMC516469 Social Sciences Environmental Sciences Fishing down the coast: Historical expansion and collapse of oyster fisheries along continental margins Michael Xavier Kirby PMCID: PMC516522 Correction Proc Natl Acad Sci U S A. 2004 August 31; 101(35): 13100. Published online 2004 August 17. doi: 10.1073/pnas.0405229101.PMCID: PMC516523 Corrects: Shivani Nautiyal, et al. The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 July 9; 99(14): 9316–9321. |
