| | This journal provides immediate access to some articles. Letters Oldest North American primate Philip D. Gingerich, Kenneth D. Rose, and Thierry Smith PMCID: PMC2656345 Reply to Gingerich et al.: Oldest North American primate K. Christopher Beard PMCID: PMC2656352 Reply to Herz et al. and Humphrey et al.: Genetic heterogeneity of cerebellar hypoplasia with quadrupedal locomotion Tayfun Ozcelik, Nurten Akarsu, Elif Uz, Safak Caglayan, Suleyman Gulsuner, Onur Emre Onat, Meliha Tan, and Uner Tan PMCID: PMC2656353 This Week in PNAS Proc Natl Acad Sci U S A. 2008 June 10; 105(23): 7895–7896. doi: 10.1073/iti2308105.PMCID: PMC2430335 Commentary Production platforms for the molecular pharming of alkaloid diversity Joe Chappell PMCID: PMC2430336 Physical Sciences Applied Physical Sciences From the Cover:
Localized and extended deformations of elastic shells Ashkan Vaziri and L. Mahadevan PMCID: PMC2430338 Chemistry Experimental evidence for a link among cupredoxins: Red, blue, and purple copper transformations in nitrous oxide reductase Masha G. Savelieff, Tiffany D. Wilson, Youssef Elias, Mark J. Nilges, Dewain K. Garner, and Yi Lu PMCID: PMC2430339 Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution Giorgio Colombo, Giulia Morra, Massimiliano Meli, and Gennady Verkhivker PMCID: PMC2402385 Geophysics X-ray Raman scattering study of MgSiO3 glass at high pressure: Implication for triclustered MgSiO3 melt in Earth's mantle Sung Keun Lee, Jung-Fu Lin, Yong Q. Cai, Nozomu Hiraoka, Peter J. Eng, Takuo Okuchi, Ho-kwang Mao, Yue Meng, Michael Y. Hu, Paul Chow, Jinfu Shu, Baosheng Li, Hiroshi Fukui, Bum Han Lee, Hyun Na Kim, and Choong-Shik Yoo PMCID: PMC2413174 Physics Cultural route to the emergence of linguistic categories Andrea Puglisi, Andrea Baronchelli, and Vittorio Loreto PMCID: PMC2430341 Biological Sciences Applied Biological Sciences From the Cover:
Characterization of the structure–function relationship at the ligament-to-bone interface Kristen L. Moffat, Wan-Hsuan S. Sun, Paul E. Pena, Nadeen O. Chahine, Stephen B. Doty, Gerard A. Ateshian, Clark T. Hung, and Helen H. Lu PMCID: PMC2430342 Biochemistry Evolution of tRNA nucleotidyltransferases: A small deletion generated CC-adding enzymes Anne Neuenfeldt, Andrea Just, Heike Betat, and Mario Mörl PMCID: PMC2430343 The coactivators CBP/p300 and the histone chaperone NAP1 promote transcription-independent nucleosome eviction at the HTLV-1 promoter Neelam Sharma and Jennifer K. Nyborg PMCID: PMC2430344 Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing Asuka Azuma-Mukai, Hideo Oguri, Toutai Mituyama, Zhi Rong Qian, Kiyoshi Asai, Haruhiko Siomi, and Mikiko C. Siomi PMCID: PMC2430345 A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate Hirohide Iwasaki, Yoshimichi Murata, Youngjun Kim, Md. Israil Hossain, Carolyn A. Worby, Jack E. Dixon, Thomas McCormack, Takehiko Sasaki, and Yasushi Okamura PMCID: PMC2430346 Biophysics Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution Giorgio Colombo, Giulia Morra, Massimiliano Meli, and Gennady Verkhivker PMCID: PMC2402385 Label-free and dynamic detection of biomolecular interactions for high-throughput microarray applications Emre Özkumur, James W. Needham, David A. Bergstein, Rodrigo Gonzalez, Mario Cabodi, Jonathan M. Gershoni, Bennett B. Goldberg, and M. Selim Ünlü PMCID: PMC2430348 Barrierless evolution of structure during the submillisecond refolding reaction of a small protein Kalyan K. Sinha and Jayant B. Udgaonkar PMCID: PMC2430349 Structure and host-cell interaction of SH1, a membrane-containing, halophilic euryarchaeal virus Harri T. Jäälinoja, Elina Roine, Pasi Laurinmäki, Hanna M. Kivelä, Dennis H. Bamford, and Sarah J. Butcher PMCID: PMC2430350 Cell Biology Yeast UCS proteins promote actomyosin interactions and limit myosin turnover in cells Matthew Lord, Thomas E. Sladewski, and Thomas D. Pollard PMCID: PMC2430351 Endosome fusion induced by diphtheria toxin translocation domain Antonella Antignani and Richard J. Youle PMCID: PMC2430352 Protein 4.1R-dependent multiprotein complex: New insights into the structural organization of the red blood cell membrane Marcela Salomao, Xihui Zhang, Yang Yang, Soohee Lee, John H. Hartwig, Joel Anne Chasis, Narla Mohandas, and Xiuli An PMCID: PMC2430353 LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of β-catenin Christopher S. Cselenyi, Kristin K. Jernigan, Emilios Tahinci, Curtis A. Thorne, Laura A. Lee, and Ethan Lee PMCID: PMC2430354 Evolution INAUGURAL ARTICLE by a Recently Elected Academy Member: Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coliZachary D. Blount, Christina Z. Borland, and Richard E. Lenski PMCID: PMC2430337 Genetics Acute carbon dioxide avoidance in Caenorhabditis elegans Elissa A. Hallem and Paul W. Sternberg PMCID: PMC2430355 A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans Andrew Jonathan Bretscher, Karl Emanuel Busch, and Mario de Bono PMCID: PMC2410288 Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition John S. K. Kauwe, Carlos Cruchaga, Kevin Mayo, Chiara Fenoglio, Sarah Bertelsen, Petra Nowotny, Daniela Galimberti, Elio Scarpini, John C. Morris, Anne M. Fagan, David M. Holtzman, and Alison M. Goate PMCID: PMC2430357 The prevalence of folate-remedial MTHFR enzyme variants in humans Nicholas J. Marini, Jennifer Gin, Janet Ziegle, Kathryn Hunkapiller Keho, David Ginzinger, Dennis A. Gilbert, and Jasper Rine PMCID: PMC2430358 Immunology From the Cover:
Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity Douglas C. Palmer, Chi-Chao Chan, Luca Gattinoni, Claudia Wrzesinski, Chrystal M. Paulos, Christian S. Hinrichs, Daniel J. Powell, Jr., Christopher A. Klebanoff, Steven E. Finkelstein, Robert N. Fariss, Zhiya Yu, Robert B. Nussenblatt, Steven A. Rosenberg, and Nicholas P. Restifo PMCID: PMC2409137 ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way Alessandra Piccini, Sonia Carta, Sara Tassi, Denise Lasiglié, Gianluca Fossati, and Anna Rubartelli PMCID: PMC2430360 Medical Sciences From the Cover:
Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita Tom Vulliamy, Richard Beswick, Michael Kirwan, Anna Marrone, Martin Digweed, Amanda Walne, and Inderjeet Dokal PMCID: PMC2430361 Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2–7 complex Douglas I. Lin, Priya Aggarwal, and J. Alan Diehl PMCID: PMC2430362 Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice Joseph A. Sennello, Raja Fayad, Maria Pini, Melissa E. Gove, Venkatesh Ponemone, Robert J. Cabay, Britta Siegmund, Charles A. Dinarello, and Giamila Fantuzzi PMCID: PMC2430363 Microbiology Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus Bo-Jian Zheng, Kwok-Wah Chan, Yong-Ping Lin, Guang-Yu Zhao, Chris Chan, Hao-Jie Zhang, Hong-Lin Chen, Samson S. Y. Wong, Susanna K. P. Lau, Patrick C. Y. Woo, Kwok-Hung Chan, Dong-Yan Jin, and Kwok-Yung Yuen PMCID: PMC2430364 From the Cover:
Experimental evidence for negative selection in the evolution of a Yersinia pestis pseudogene Yi-Cheng Sun, B. Joseph Hinnebusch, and Creg Darby PMCID: PMC2430365 A korarchaeal genome reveals insights into the evolution of the Archaea James G. Elkins, Mircea Podar, David E. Graham, Kira S. Makarova, Yuri Wolf, Lennart Randau, Brian P. Hedlund, Céline Brochier-Armanet, Victor Kunin, Iain Anderson, Alla Lapidus, Eugene Goltsman, Kerrie Barry, Eugene V. Koonin, Phil Hugenholtz, Nikos Kyrpides, Gerhard Wanner, Paul Richardson, Martin Keller, and Karl O. Stetter PMCID: PMC2430366 Neuroscience Neural substrates underlying human delay and trace eyeblink conditioning Dominic T. Cheng, John F. Disterhoft, John M. Power, Deborah A. Ellis, and John E. Desmond PMCID: PMC2430367 GDNF is a fast-acting potent inhibitor of alcohol consumption and relapse Sebastien Carnicella, Viktor Kharazia, Jerome Jeanblanc, Patricia H. Janak, and Dorit Ron PMCID: PMC2423415 Eyeblink conditioning in 12-day-old rats using pontine stimulation as the conditioned stimulus Matthew M. Campolattaro and John H. Freeman PMCID: PMC2430369 Functional integration across a gradient of corticostriatal channels controls UP state transitions in the dorsal striatum Fernando Kasanetz, Luis A. Riquelme, Valeria Della-Maggiore, Patricio O'Donnell, and M. Gustavo Murer PMCID: PMC2430370 The tactile integration of local motion cues is analogous to its visual counterpart Y. C. Pei, S. S. Hsiao, and S. J. Bensmaia PMCID: PMC2430371 Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex Lawrence K. Low, Xiao-Bo Liu, Regina L. Faulkner, Jeffrey Coble, and Hwai-Jong Cheng PMCID: PMC2430372 Metaplastic control of the endocannabinoid system at inhibitory synapses in hippocampus David A. Edwards, Longhua Zhang, and Bradley E. Alger PMCID: PMC2409138 Physiology Predisposition to late-onset obesity in GIRK4 knockout mice Cydne A. Perry, Marco Pravetoni, Jennifer A. Teske, Carolina Aguado, Darin J. Erickson, Juan F. Medrano, Rafael Luján, Catherine M. Kotz, and Kevin Wickman PMCID: PMC2430374 Calmodulin-dependent gating of Cav1.2 calcium channels in the absence of Cavβ subunits Arippa Ravindran, Qi Zong Lao, Jo Beth Harry, Parwiz Abrahimi, Evgeny Kobrinsky, and Nikolai M. Soldatov PMCID: PMC2430375 Social Sciences Psychology Neural substrates underlying human delay and trace eyeblink conditioning Dominic T. Cheng, John F. Disterhoft, John M. Power, Deborah A. Ellis, and John E. Desmond PMCID: PMC2430367 Social Sciences Cultural route to the emergence of linguistic categories Andrea Puglisi, Andrea Baronchelli, and Vittorio Loreto PMCID: PMC2430341 Corrections Correction for Jarvis et al., A global perspective of the richness and evenness of traditional crop-variety diversity maintained by farming communities PMCID: PMC2430376 Corrects: Devra I. Jarvis, et al. From the Cover:
A global perspective of the richness and evenness of traditional crop-variety diversity maintained by farming communities. Proc Natl Acad Sci U S A. 2008 April 8; 105(14): 5326–5331. Correction for Mossman, Profile of Hans Joachim Schellnhuber PMCID: PMC2430377 Corrects: Kaspar Mossman. Profile of Hans Joachim Schellnhuber. Proc Natl Acad Sci U S A. 2008 February 12; 105(6): 1783–1785. Correction for Yokoyama et al., The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals PMCID: PMC2430378 Corrects: Utako Yokoyama, et al. The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals. Proc Natl Acad Sci U S A. 2008 April 29; 105(17): 6386–6391. Correction for Xu et al., The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis PMCID: PMC2430379 Corrects: Zhao Xu, et al. The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis. Proc Natl Acad Sci U S A. 2008 February 19; 105(7): 2421–2426. |
