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Volume 36(5);  March 2008
Molecular Biology
A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response
Paolo Benatti, Valentina Basile, Daniele Merico, Luca Isaia Fantoni, Enrico Tagliafico, and Carol Imbriano
Nucleic Acids Res. 2008 March; 36(5): 1415–1428. Published online 2008 March. doi: 10.1093/nar/gkm1046.
PMCID: PMC2275158
Transcription regulation of the type II restriction-modification system AhdI
Ekaterina Bogdanova, Marko Djordjevic, Ioanna Papapanagiotou, Tomasz Heyduk, Geoff Kneale, and Konstantin Severinov
Nucleic Acids Res. 2008 March; 36(5): 1429–1442. Published online 2008 March. doi: 10.1093/nar/gkm1116.
PMCID: PMC2275141
Insights into the selective activation of alternatively used splice acceptors by the human immunodeficiency virus type-1 bidirectional splicing enhancer
Corinna Asang, Ilona Hauber, and Heiner Schaal
Nucleic Acids Res. 2008 March; 36(5): 1450–1463. Published online 2008 March. doi: 10.1093/nar/gkm1147.
PMCID: PMC2275126
Regulation of the MAD1 promoter by G-CSF
Kan Jiang, Nadine Hein, Kolja Eckert, Juliane Lüscher-Firzlaff, and Bernhard Lüscher
Nucleic Acids Res. 2008 March; 36(5): 1517–1531. Published online 2008 March. doi: 10.1093/nar/gkn002.
PMCID: PMC2275144
Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
Amira Zaky, Carlos Busso, Tadahide Izumi, Ranajoy Chattopadhyay, Ahmad Bassiouny, Sankar Mitra, and Kishor K. Bhakat
Nucleic Acids Res. 2008 March; 36(5): 1555–1566. Published online 2008 March. doi: 10.1093/nar/gkm1173.
PMCID: PMC2275136
Primary T-lymphocytes rescue the replication of HIV-1 DIS RNA mutants in part by facilitating reverse transcription
Kate L. Jones, Secondo Sonza, and Johnson Mak
Nucleic Acids Res. 2008 March; 36(5): 1578–1588. Published online 2008 March. doi: 10.1093/nar/gkm1149.
PMCID: PMC2275147
Histone H1 functions as a stimulatory factor in backup pathways of NHEJ
Bustanur Rosidi, Minli Wang, Wenqi Wu, Aparna Sharma, Huichen Wang, and George Iliakis
Nucleic Acids Res. 2008 March; 36(5): 1610–1623. Published online 2008 March. doi: 10.1093/nar/gkn013.
PMCID: PMC2275134
Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65
Christine Buerki, Karin M. Rothgiesser, Taras Valovka, Heather R. Owen, Hubert Rehrauer, Monika Fey, William S. Lane, and Michael O. Hottiger
Nucleic Acids Res. 2008 March; 36(5): 1665–1680. Published online 2008 March. doi: 10.1093/nar/gkn003.
PMCID: PMC2275151
Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)
Ju Youn Beak, Hong Soon Kang, Yong-Sik Kim, and Anton M. Jetten
Nucleic Acids Res. 2008 March; 36(5): 1690–1702. Published online 2008 March. doi: 10.1093/nar/gkn009.
PMCID: PMC2275160
Spliceosomal introns as tools for genomic and evolutionary analysis
Manuel Irimia and Scott William Roy
Nucleic Acids Res. 2008 March; 36(5): 1703–1712. Published online 2008 March. doi: 10.1093/nar/gkn012.
PMCID: PMC2275149
Interaction of p21CDKN1A with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair
Ornella Cazzalini, Paola Perucca, Monica Savio, Daniela Necchi, Livia Bianchi, Lucia A. Stivala, Bernard Ducommun, A. Ivana Scovassi, and Ennio Prosperi
Nucleic Acids Res. 2008 March; 36(5): 1713–1722. Published online 2008 March. doi: 10.1093/nar/gkn014.
PMCID: PMC2275133
Analysis of transcription factor interactions in osteoblasts using competitive chromatin immunoprecipitation
Hernan Roca and Renny T. Franceschi
Nucleic Acids Res. 2008 March; 36(5): 1723–1730. Published online 2008 March. doi: 10.1093/nar/gkn022.
PMCID: PMC2275161
Role of ATM in the telomere response to the G-quadruplex ligand 360A
Gaëlle Pennarun, Christine Granotier, Françoise Hoffschir, Eliane Mandine, Denis Biard, Laurent R. Gauthier, and François D. Boussin
Nucleic Acids Res. 2008 March; 36(5): 1741–1754. Published online 2008 March. doi: 10.1093/nar/gkn026.
PMCID: PMC2275132
RNA
Sequence-function relationships provide new insight into the cleavage site selectivity of the 8–17 RNA-cleaving deoxyribozyme
Kenny Schlosser, Jimmy Gu, Lauren Sule, and Yingfu Li
Nucleic Acids Res. 2008 March; 36(5): 1472–1481. Published online 2008 March. doi: 10.1093/nar/gkm1175.
PMCID: PMC2275145
rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance
Rasa Rakauskaitė and Jonathan D. Dinman
Nucleic Acids Res. 2008 March; 36(5): 1497–1507. Published online 2008 March. doi: 10.1093/nar/gkm1179.
PMCID: PMC2275155
Proton-guided movements of tRNA within the Leishmania mitochondrial RNA import complex
Sudarshana Basu, Saikat Mukherjee, and Samit Adhya
Nucleic Acids Res. 2008 March; 36(5): 1599–1609. Published online 2008 March. doi: 10.1093/nar/gkn010.
PMCID: PMC2275131
Deadenylation-independent stage-specific mRNA degradation in Leishmania
Simon Haile, Aurélien Dupé, and Barbara Papadopoulou
Nucleic Acids Res. 2008 March; 36(5): 1634–1644. Published online 2008 March. doi: 10.1093/nar/gkn019.
PMCID: PMC2275140
Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications
Veronica K. Coventry and Graeme L. Conn
Nucleic Acids Res. 2008 March; 36(5): 1645–1653. Published online 2008 March. doi: 10.1093/nar/gkn020.
PMCID: PMC2275154
Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation
Tao Sun and Yi Zhang
Nucleic Acids Res. 2008 March; 36(5): 1654–1664. Published online 2008 March. doi: 10.1093/nar/gkm1180.
PMCID: PMC2275129
Structural Biology
Influence of the incorporation of a cyclohexenyl nucleic acid (CeNA) residue onto the sequence d(CGCGAATTCGCG)
Koen Robeyns, Piet Herdewijn, and Luc Van Meervelt
Nucleic Acids Res. 2008 March; 36(5): 1407–1414. Published online 2008 March. doi: 10.1093/nar/gkm1132.
PMCID: PMC2275148
Interaction of cationic surfactants with DNA: a single-molecule study
Sudhir Husale, Wilfried Grange, Marc Karle, Stephan Bürgi, and Martin Hegner
Nucleic Acids Res. 2008 March; 36(5): 1443–1449. Published online 2008 March. doi: 10.1093/nar/gkm1146.
PMCID: PMC2275125
Insights into structure, dynamics and hydration of locked nucleic acid (LNA) strand-based duplexes from molecular dynamics simulations
Vineet Pande and Lennart Nilsson
Nucleic Acids Res. 2008 March; 36(5): 1508–1516. Published online 2008 March. doi: 10.1093/nar/gkm1182.
PMCID: PMC2275159
Stretching and unzipping nucleic acid hairpins using a synthetic nanopore
Q. Zhao, J. Comer, V. Dimitrov, S. Yemenicioglu, A. Aksimentiev, and G. Timp
Nucleic Acids Res. 2008 March; 36(5): 1532–1541. Published online 2008 March. doi: 10.1093/nar/gkm1017.
PMCID: PMC2275135
The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site
Alexander B. Taylor, Britta Meyer, Belinda Z. Leal, Peter Kötter, Virgil Schirf, Borries Demeler, P. John Hart, Karl-Dieter Entian, and Jens Wöhnert
Nucleic Acids Res. 2008 March; 36(5): 1542–1554. Published online 2008 March. doi: 10.1093/nar/gkm1172.
PMCID: PMC2275143
Crystal structure of IcaR, a repressor of the TetR family implicated in biofilm formation in Staphylococcus epidermidis
Wen-Yih Jeng, Tzu-Ping Ko, Chia-I Liu, Rey-Ting Guo, Chien-Liang Liu, Hui-Lin Shr, and Andrew H.-J. Wang
Nucleic Acids Res. 2008 March; 36(5): 1567–1577. Published online 2008 March. doi: 10.1093/nar/gkm1176.
PMCID: PMC2275139
Probing the mechanism of recognition of ssDNA by the Cdc13-DBD
Aimee M. Eldridge and Deborah S. Wuttke
Nucleic Acids Res. 2008 March; 36(5): 1624–1633. Published online 2008 March. doi: 10.1093/nar/gkn017.
PMCID: PMC2275150
Solution structure of stem-loop α of the hepatitis B virus post-transcriptional regulatory element
Martin Schwalbe, Oliver Ohlenschläger, Aliaksandr Marchanka, Ramadurai Ramachandran, Sabine Häfner, Tilman Heise, and Matthias Görlach
Nucleic Acids Res. 2008 March; 36(5): 1681–1689. Published online 2008 March. doi: 10.1093/nar/gkn006.
PMCID: PMC2275152
Chemistry
Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences
Takumi Ishizuka, Junya Yoshida, Yoji Yamamoto, Jun Sumaoka, Tullia Tedeschi, Roberto Corradini, Stefano Sforza, and Makoto Komiyama
Nucleic Acids Res. 2008 March; 36(5): 1464–1471. Published online 2008 March. doi: 10.1093/nar/gkm1154.
PMCID: PMC2275137
Methods Online
Discriminating single-base difference miRNA expressions using microarray Probe Design Guru (ProDeG)
Inhan Lee, Subramanian S. Ajay, Haiming Chen, Atsushi Maruyama, Nulang Wang, Melvin G. McInnis, and Brian D. Athey
Nucleic Acids Res. 2008 March; 36(5): e27. Published online 2008 March. doi: 10.1093/nar/gkm1165.
PMCID: PMC2275156
Improvement of reporter activity by IRES-mediated polycistronic reporter system
Hicham Bouabe, Reinhard Fässler, and Jürgen Heesemann
Nucleic Acids Res. 2008 March; 36(5): e28. Published online 2008 March. doi: 10.1093/nar/gkm1119.
PMCID: PMC2275123
Predicting RNA-binding sites from the protein structure based on electrostatics, evolution and geometry
Yao Chi Chen and Carmay Lim
Nucleic Acids Res. 2008 March; 36(5): e29. Published online 2008 March. doi: 10.1093/nar/gkn008.
PMCID: PMC2275128
Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons
Won Jong Rhee, Philip J. Santangelo, Hanjoong Jo, and Gang Bao
Nucleic Acids Res. 2008 March; 36(5): e30. Published online 2008 March. doi: 10.1093/nar/gkn039.
PMCID: PMC2275124
Facile SNP detection using bifunctional, cross-linking oligonucleotide probes
Xiaohua Peng and Marc M. Greenberg
Nucleic Acids Res. 2008 March; 36(5): e31. Published online 2008 March. doi: 10.1093/nar/gkn052.
PMCID: PMC2275146
The use of multiple displacement amplification to amplify complex DNA libraries
Melissa J. Fullwood, Jack J. S. Tan, Patrick W. P. Ng, Kuo Ping Chiu, Jun Liu, Chia Lin Wei, and Yijun Ruan
Nucleic Acids Res. 2008 March; 36(5): e32. Published online 2008 March. doi: 10.1093/nar/gkn074.
PMCID: PMC2275127
Performance comparison between k-tuple distance and four model-based distances in phylogenetic tree reconstruction
Kuan Yang and Liqing Zhang
Nucleic Acids Res. 2008 March; 36(5): e33. Published online 2008 March. doi: 10.1093/nar/gkn075.
PMCID: PMC2275138
Bisulfite sequencing Data Presentation and Compilation (BDPC) web server—a useful tool for DNA methylation analysis
Christian Rohde, Yingying Zhang, Tomasz P. Jurkowski, Heinrich Stamerjohanns, Richard Reinhardt, and Albert Jeltsch
Nucleic Acids Res. 2008 March; 36(5): e34. Published online 2008 March. doi: 10.1093/nar/gkn083.
PMCID: PMC2275153
Computational Biology
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA
Dmitry B. Veprintsev and Alan R. Fersht
Nucleic Acids Res. 2008 March; 36(5): 1589–1598. Published online 2008 March. doi: 10.1093/nar/gkm1040.
PMCID: PMC2275157
Nucleic Acid Enzymes
Identification and characterization of coumestans as novel HCV NS5B polymerase inhibitors
Neerja Kaushik-Basu, Alain Bopda-Waffo, Tanaji T. Talele, Amartya Basu, Paulo R. R. Costa, Alcides J. M. da Silva, Stefan G. Sarafianos, and François Noël
Nucleic Acids Res. 2008 March; 36(5): 1482–1496. Published online 2008 March. doi: 10.1093/nar/gkm1178.
PMCID: PMC2275130
Substitution of a residue contacting the triphosphate moiety of the incoming nucleotide increases the fidelity of yeast DNA polymerase ζ
Craig A. Howell, Christine M. Kondratick, and M. Todd Washington
Nucleic Acids Res. 2008 March; 36(5): 1731–1740. Published online 2008 March. doi: 10.1093/nar/gkn023.
PMCID: PMC2275142
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