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Volume 104(47);  November 20, 2007
Biological Science
Applied Biological Sciences
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade
John S. Rudge, Jocelyn Holash, Donna Hylton, Michelle Russell, Shelly Jiang, Raymond Leidich, Nicholas Papadopoulos, Erica A. Pyles, Al Torri, Stanley J. Wiegand, Gavin Thurston, Neil Stahl, and George D. Yancopoulos
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18363–18370. Published online 2007 November 13. doi: 10.1073/pnas.0708865104.
PMCID: PMC2141784
Inaugural Article
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade
John S. Rudge, Jocelyn Holash, Donna Hylton, Michelle Russell, Shelly Jiang, Raymond Leidich, Nicholas Papadopoulos, Erica A. Pyles, Al Torri, Stanley J. Wiegand, Gavin Thurston, Neil Stahl, and George D. Yancopoulos
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18363–18370. Published online 2007 November 13. doi: 10.1073/pnas.0708865104.
PMCID: PMC2141784
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18345–18346. doi: 10.1073/iti4707104.
PMCID: PMC2141778
Commentaries
Decline and fall of the tumor suppressor
George Hinkal and Lawrence A. Donehower
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18347–18348. Published online 2007 November 12. doi: 10.1073/pnas.0709330104.
PMCID: PMC2141779
Getting a grip on calcium regulation
Mordecai P. Blaustein, Thomas H. Charpentier, and David J. Weber
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18349–18350. Published online 2007 November 14. doi: 10.1073/pnas.0709008104.
PMCID: PMC2141780
When HIV spread afar
Edward C. Holmes
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18351–18352. Published online 2007 November 14. doi: 10.1073/pnas.0709179104.
PMCID: PMC2141781
Carbon cycle conundrums
David Schimel
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18353–18354. Published online 2007 November 12. doi: 10.1073/pnas.0709331104.
PMCID: PMC2141782
Perspective
Substrate activation for O2 reactions by oxidized metal centers in biology
Monita Y. M. Pau, John D. Lipscomb, and Edward I. Solomon
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18355–18362. Published online 2007 November 14. doi: 10.1073/pnas.0704191104.
PMCID: PMC2141783
Physical Sciences
Applied Mathematics
A tensor higher-order singular value decomposition for integrative analysis of DNA microarray data from different studies
Larsson Omberg, Gene H. Golub, and Orly Alter
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18371–18376. Published online 2007 November 14. doi: 10.1073/pnas.0709146104.
PMCID: PMC2147680
Dynamical quorum sensing: Population density encoded in cellular dynamics
Silvia De Monte, Francesco d'Ovidio, Sune Danø, and Preben Graae Sørensen
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18377–18381. Published online 2007 November 14. doi: 10.1073/pnas.0706089104.
PMCID: PMC2141785
Applied Physical Sciences
Faceting ionic shells into icosahedra via electrostatics
Graziano Vernizzi and Monica Olvera de la Cruz
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18382–18386. Published online 2007 November 14. doi: 10.1073/pnas.0703431104.
PMCID: PMC2141786
The anomalous behavior of the density of water in the range 30 K < T < 373 K
Francesco Mallamace, Caterina Branca, Matteo Broccio, Carmelo Corsaro, Chung-Yuan Mou, and Sow-Hsin Chen
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18387–18391. Published online 2007 November 13. doi: 10.1073/pnas.0706504104.
PMCID: PMC2141787
A self-consistent theory for graphene transport
Shaffique Adam, E. H. Hwang, V. M. Galitski, and S. Das Sarma
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18392–18397. Published online 2007 November 14. doi: 10.1073/pnas.0704772104.
PMCID: PMC2141788
Chemistry
On anti-portfolio effects in science and technology with application to reaction kinetics, chemical synthesis, and molecular biology
Marcel O. Vlad, Alexandru Dan Corlan, Vlad T. Popa, and John Ross
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18398–18403. Published online 2007 November 14. doi: 10.1073/pnas.0708624104.
PMCID: PMC2147681
From the Cover:
Mapping hydration dynamics around a protein surface
Luyuan Zhang, Lijuan Wang, Ya-Ting Kao, Weihong Qiu, Yi Yang, Oghaghare Okobiah, and Dongping Zhong
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18461–18466. Published online 2007 November 14. doi: 10.1073/pnas.0707647104.
PMCID: PMC2141799
Geology
From the Cover:
The relative importance of directional change, random walks, and stasis in the evolution of fossil lineages
Gene Hunt
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18404–18408. Published online 2007 November 14. doi: 10.1073/pnas.0704088104.
PMCID: PMC2141789
Physics
Attosecond electron pulses for 4D diffraction and microscopy
Peter Baum and Ahmed H. Zewail
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18409–18414. Published online 2007 November 13. doi: 10.1073/pnas.0709019104.
PMCID: PMC2141790
Anyonic braiding in optical lattices
Chuanwei Zhang, V. W. Scarola, Sumanta Tewari, and S. Das Sarma
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18415–18420. Published online 2007 November 13. doi: 10.1073/pnas.0709075104.
PMCID: PMC2141791
Biological Sciences
Agricultural Sciences
Genetic diversity of citrus bacterial canker pathogens preserved in herbarium specimens
Wenbin Li, Qijian Song, Ronald H. Brlansky, and John S. Hartung
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18427–18432. Published online 2007 November 12. doi: 10.1073/pnas.0705590104.
PMCID: PMC2141793
Biochemistry
Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding
Adam W. Barb, Ling Jiang, Christian R. H. Raetz, and Pei Zhou
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18433–18438. Published online 2007 November 19. doi: 10.1073/pnas.0709412104.
PMCID: PMC2141794
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
SunHwa Hong, Young-Wook Cho, Li-Rong Yu, Hong Yu, Timothy D. Veenstra, and Kai Ge
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18439–18444. Published online 2007 November 14. doi: 10.1073/pnas.0707292104.
PMCID: PMC2141795
Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
Laure Yatime, Yves Mechulam, Sylvain Blanquet, and Emmanuelle Schmitt
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18445–18450. Published online 2007 November 13. doi: 10.1073/pnas.0706784104.
PMCID: PMC2141796
A quantum-chemical picture of hemoglobin affinity
R. E. Alcantara, C. Xu, T. G. Spiro, and V. Guallar
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18451–18455. Published online 2007 November 14. doi: 10.1073/pnas.0706026104.
PMCID: PMC2141797
Identification of enzymes and regulatory proteins in Escherichia coli that are oxidized under nitrogen, carbon, or phosphate starvation
Yasuko Noda, Barbara S. Berlett, Earl R. Stadtman, Angel Aponte, Meghan Morgan, and Rong-Fong Shen
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18456–18460. Published online 2007 November 14. doi: 10.1073/pnas.0709368104.
PMCID: PMC2141798
Biophysics
From the Cover:
Mapping hydration dynamics around a protein surface
Luyuan Zhang, Lijuan Wang, Ya-Ting Kao, Weihong Qiu, Yi Yang, Oghaghare Okobiah, and Dongping Zhong
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18461–18466. Published online 2007 November 14. doi: 10.1073/pnas.0707647104.
PMCID: PMC2141799
From the Cover:
The second Ca2+-binding domain of the Na+–Ca2+ exchanger is essential for regulation: Crystal structures and mutational analysis
Gabriel Mercado Besserer, Michela Ottolia, Debora A. Nicoll, Vincent Chaptal, Duilio Cascio, Kenneth D. Philipson, and Jeff Abramson
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18467–18472. Published online 2007 October 25. doi: 10.1073/pnas.0707417104.
PMCID: PMC2141800
Measurement of bond vector orientations in invisible excited states of proteins
Pramodh Vallurupalli, D. Flemming Hansen, Elliott Stollar, Eva Meirovitch, and Lewis E. Kay
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18473–18477. Published online 2007 November 15. doi: 10.1073/pnas.0708296104.
PMCID: PMC2141801
Identification of the βTP site in the x-ray structure of F1-ATPase as the high-affinity catalytic site
Hui Z. Mao and Joachim Weber
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18478–18483. Published online 2007 November 14. doi: 10.1073/pnas.0709322104.
PMCID: PMC2141802
Structural basis for regulation of bifunctional roles in replication initiator protein
Akira Nakamura, Chieko Wada, and Kunio Miki
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18484–18489. Published online 2007 November 13. doi: 10.1073/pnas.0705623104.
PMCID: PMC2141803
Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria
Nathalie Declerck, Laurent Bouillaut, Denis Chaix, Nathalie Rugani, Leyla Slamti, François Hoh, Didier Lereclus, and Stefan T. Arold
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18490–18495. Published online 2007 November 12. doi: 10.1073/pnas.0704501104.
PMCID: PMC2141804
Large-scale allosteric conformational transitions of adenylate kinase appear to involve a population-shift mechanism
Karunesh Arora and Charles L. Brooks, III
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18496–18501. Published online 2007 November 13. doi: 10.1073/pnas.0706443104.
PMCID: PMC2141805
Cell Biology
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor
Anuradha Pradhan, Que T. Lambert, and Gary W. Reuther
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18502–18507. Published online 2007 November 14. doi: 10.1073/pnas.0702388104.
PMCID: PMC2141806
Cytochrome c oxidase regulates endogenous nitric oxide availability in respiring cells: A possible explanation for hypoxic vasodilation
Miriam Palacios-Callender, Veronica Hollis, Miriam Mitchison, Nanci Frakich, David Unitt, and Salvador Moncada
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18508–18513. Published online 2007 November 14. doi: 10.1073/pnas.0709440104.
PMCID: PMC2141807
Epithelial NF-κB activation promotes urethane-induced lung carcinogenesis
Georgios T. Stathopoulos, Taylor P. Sherrill, Dong-Sheng Cheng, Robert M. Scoggins, Wei Han, Vasiliy V. Polosukhin, Linda Connelly, Fiona E. Yull, Barbara Fingleton, and Timothy S. Blackwell
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18514–18519. Published online 2007 November 13. doi: 10.1073/pnas.0705316104.
PMCID: PMC2141808
The dynamic phagosomal proteome and the contribution of the endoplasmic reticulum
Lindsay D. Rogers and Leonard J. Foster
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18520–18525. Published online 2007 November 15. doi: 10.1073/pnas.0705801104.
PMCID: PMC2141809
Structural basis for recruitment of mitochondrial fission complexes by Fis1
Yan Zhang and David C. Chan
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18526–18530. Published online 2007 November 12. doi: 10.1073/pnas.0706441104.
PMCID: PMC2141810
Developmental Biology
Distinct roles of Wnt/β-catenin and Bmp signaling during early cardiogenesis
Alexandra Klaus, Yumiko Saga, Makoto M. Taketo, Eldad Tzahor, and Walter Birchmeier
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18531–18536. Published online 2007 November 13. doi: 10.1073/pnas.0703113104.
PMCID: PMC2141811
An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line
Elena Zvaritch, Frederic Depreux, Natasha Kraeva, Ryan E. Loy, Sanjeewa A. Goonasekera, Simona Boncompagni, Alexander Kraev, Anthony O. Gramolini, Robert T. Dirksen, Clara Franzini-Armstrong, Christine E. Seidman, J. G. Seidman, and David H. MacLennan
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18537–18542. Published online 2007 November 14. doi: 10.1073/pnas.0709312104.
PMCID: PMC2141812
Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of Drosophila Myc
Nanami Senoo-Matsuda and Laura A. Johnston
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18543–18548. Published online 2007 November 13. doi: 10.1073/pnas.0709021104.
PMCID: PMC2141813
Cell adhesion and cortex contractility determine cell patterning in the Drosophilaretina
Jos Käfer, Takashi Hayashi, Athanasius F. M. Marée, Richard W. Carthew, and François Graner
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18549–18554. Published online 2007 November 14. doi: 10.1073/pnas.0704235104.
PMCID: PMC2141814
Ecology
Quantifying the biodiversity value of tropical primary, secondary, and plantation forests
J. Barlow, T. A. Gardner, I. S. Araujo, T. C. Ávila-Pires, A. B. Bonaldo, J. E. Costa, M. C. Esposito, L. V. Ferreira, J. Hawes, M. I. M. Hernandez, M. S. Hoogmoed, R. N. Leite, N. F. Lo-Man-Hung, J. R. Malcolm, M. B. Martins, L. A. M. Mestre, R. Miranda-Santos, A. L. Nunes-Gutjahr, W. L. Overal, L. Parry, S. L. Peters, M. A. Ribeiro-Junior, M. N. F. da Silva, C. da Silva Motta, and C. A. Peres
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18555–18560. Published online 2007 November 14. doi: 10.1073/pnas.0703333104.
PMCID: PMC2141815
A cold phase of the East Pacific triggers new phytoplankton blooms in San Francisco Bay
James E. Cloern, Alan D. Jassby, Janet K. Thompson, and Kathryn A. Hieb
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18561–18565. Published online 2007 November 13. doi: 10.1073/pnas.0706151104.
PMCID: PMC2141816
Evolution
From the Cover:
The relative importance of directional change, random walks, and stasis in the evolution of fossil lineages
Gene Hunt
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18404–18408. Published online 2007 November 14. doi: 10.1073/pnas.0704088104.
PMCID: PMC2141789
From the Cover:
The emergence of HIV/AIDS in the Americas and beyond
M. Thomas P. Gilbert, Andrew Rambaut, Gabriela Wlasiuk, Thomas J. Spira, Arthur E. Pitchenik, and Michael Worobey
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18566–18570. Published online 2007 October 31. doi: 10.1073/pnas.0705329104.
PMCID: PMC2141817
A recurrent inversion on the eutherian X chromosome
Mario Cáceres, National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program, Robert T. Sullivan, and James W. Thomas
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18571–18576. Published online 2007 November 14. doi: 10.1073/pnas.0706604104.
PMCID: PMC2141818
Simpler mode of inheritance of transcriptional variation in male Drosophila melanogaster
Marta L. Wayne, Marina Telonis-Scott, Lisa M. Bono, Larry Harshman, Artyom Kopp, Sergey V. Nuzhdin, and Lauren M. McIntyre
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18577–18582. Published online 2007 November 14. doi: 10.1073/pnas.0705441104.
PMCID: PMC2141819
Coevolutionary networks of splicing cis-regulatory elements
Xinshu Xiao, Zefeng Wang, Minyoung Jang, and Christopher B. Burge
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18583–18588. Published online 2007 November 12. doi: 10.1073/pnas.0707349104.
PMCID: PMC2141820
Sympatric speciation by allochrony in a seabird
V. L. Friesen, A. L. Smith, E. Gómez-Díaz, M. Bolton, R. W. Furness, J. González-Solís, and L. R. Monteiro
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18589–18594. Published online 2007 November 15. doi: 10.1073/pnas.0700446104.
PMCID: PMC2141821
Phylogenetic analysis of the scaling of wet and dry biological fibrillar adhesives
A. M. Peattie and R. J. Full
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18595–18600. Published online 2007 November 13. doi: 10.1073/pnas.0707591104.
PMCID: PMC2141822
Genetics
A tensor higher-order singular value decomposition for integrative analysis of DNA microarray data from different studies
Larsson Omberg, Gene H. Golub, and Orly Alter
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18371–18376. Published online 2007 November 14. doi: 10.1073/pnas.0709146104.
PMCID: PMC2147680
On anti-portfolio effects in science and technology with application to reaction kinetics, chemical synthesis, and molecular biology
Marcel O. Vlad, Alexandru Dan Corlan, Vlad T. Popa, and John Ross
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18398–18403. Published online 2007 November 14. doi: 10.1073/pnas.0708624104.
PMCID: PMC2147681
The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-κB target genes
Susanne Wolfrum, Daniel Teupser, Marietta Tan, Kwan Y. Chen, and Jan L. Breslow
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18601–18606. Published online 2007 November 15. doi: 10.1073/pnas.0709011104.
PMCID: PMC2141823
Allelic variant in CTLA4 alters T cell phosphorylation patterns
Lisa M. Maier, David E. Anderson, Philip L. De Jager, Linda S. Wicker, and David A. Hafler
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18607–18612. Published online 2007 November 13. doi: 10.1073/pnas.0706409104.
PMCID: PMC2141824
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
Ting Wang, Jue Zeng, Craig B. Lowe, Robert G. Sellers, Sofie R. Salama, Min Yang, Shawn M. Burgess, Rainer K. Brachmann, and David Haussler
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18613–18618. Published online 2007 November 14. doi: 10.1073/pnas.0703637104.
PMCID: PMC2141825
Immunology
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis
Tomoko Hayashi, Ji-Hun Mo, Xing Gong, Cyprian Rossetto, Angela Jang, Lucinda Beck, Gregory I. Elliott, Irina Kufareva, Ruben Abagyan, David H. Broide, Jongdae Lee, and Eyal Raz
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18619–18624. Published online 2007 November 14. doi: 10.1073/pnas.0709261104.
PMCID: PMC2141826
Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease
F. Odoardi, N. Kawakami, W. E. F. Klinkert, H. Wekerle, and A. Flügel
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18625–18630. Published online 2007 November 13. doi: 10.1073/pnas.0705033104.
PMCID: PMC2141827
Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2
Nicholas Funderburg, Michael M. Lederman, Zhimin Feng, Michael G. Drage, Julie Jadlowsky, Clifford V. Harding, Aaron Weinberg, and Scott F. Sieg
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18631–18635. doi: 10.1073/PNAS.0702130104.
PMCID: PMC2141828
Medical Sciences
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression
Min Li, Yuqing Zhang, Zijuan Liu, Uddalak Bharadwaj, Hao Wang, Xinwen Wang, Sheng Zhang, Juan P. Liuzzi, Shou-Mei Chang, Robert J. Cousins, William E. Fisher, F. Charles Brunicardi, Craig D. Logsdon, Changyi Chen, and Qizhi Yao
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18636–18641. Published online 2007 November 14. doi: 10.1073/pnas.0709307104.
PMCID: PMC2141829
Clonogenic mast cell progenitors and their excess numbers in chimeric BALB/c mice with inactivated GATA-1
Donald Metcalf, Ian Majewski, Sandra Mifsud, Ladina Di Rago, and Warren S. Alexander
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18642–18647. Published online 2007 November 13. doi: 10.1073/pnas.0709625104.
PMCID: PMC2141830
Protection against simian/human immunodeficiency virus (SHIV) 89.6P in macaques after coimmunization with SHIV antigen and IL-15 plasmid
Jean D. Boyer, Tara M. Robinson, Michele A. Kutzler, Gordon Vansant, David A. Hokey, Sanjeev Kumar, Rose Parkinson, Ling Wu, Maninder K. Sidhu, George N. Pavlakis, Barbara K. Felber, Charles Brown, Peter Silvera, Mark G. Lewis, Joseph Monforte, Thomas A. Waldmann, John Eldridge, and David B. Weiner
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18648–18653. Published online 2007 November 13. doi: 10.1073/pnas.0709198104.
PMCID: PMC2141831
Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
Lanlan Shen, Minoru Toyota, Yutaka Kondo, E Lin, Li Zhang, Yi Guo, Natalie Supunpong Hernandez, Xinli Chen, Saira Ahmed, Kazuo Konishi, Stanley R. Hamilton, and Jean-Pierre J. Issa
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18654–18659. Published online 2007 November 14. doi: 10.1073/pnas.0704652104.
PMCID: PMC2141832
IL-1 receptor accessory protein is essential for IL-33-induced activation of T lymphocytes and mast cells
Shafaqat Ali, Michael Huber, Christian Kollewe, Stephan C. Bischoff, Werner Falk, and Michael U. Martin
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18660–18665. Published online 2007 November 14. doi: 10.1073/pnas.0705939104.
PMCID: PMC2141833
Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin E
Hua Huang, Yan Chen, and Jin Ye
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18666–18670. Published online 2007 November 14. doi: 10.1073/pnas.0708423104.
PMCID: PMC2141834
Growth inhibition of non-small-cell lung carcinoma by BN/GRP antagonist is linked with suppression of K-Ras, COX-2, and pAkt
Florian Hohla, Andrew V. Schally, Celia A. Kanashiro, Stefan Buchholz, Benjamin Baker, Chandrika Kannadka, Angelika Moder, Elmar Aigner, Christian Datz, and Gabor Halmos
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18671–18676. Published online 2007 November 14. doi: 10.1073/pnas.0709455104.
PMCID: PMC2141835
A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension
Minghui Xiang, Mingye Feng, Sabina Muend, and Rajini Rao
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18677–18681. Published online 2007 November 13. doi: 10.1073/pnas.0707120104.
PMCID: PMC2141836
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
Tao Liu, Andrew E. L. Tee, Antonio Porro, Stewart A. Smith, Tanya Dwarte, Pei Yan Liu, Nunzio Iraci, Eric Sekyere, Michelle Haber, Murray D. Norris, Daniel Diolaiti, Giuliano Della Valle, Giovanni Perini, and Glenn M. Marshall
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18682–18687. Published online 2007 November 14. doi: 10.1073/pnas.0705524104.
PMCID: PMC2141837
Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure
Shengqiang Yu, Karl Hackmann, Jianggang Gao, Xiaobing He, Klaus Piontek, Miguel A. García González, Luis F. Menezes, Hangxue Xu, Gregory G. Germino, Jian Zuo, and Feng Qian
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18688–18693. Published online 2007 November 14. doi: 10.1073/pnas.0708217104.
PMCID: PMC2141838
RARα-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia
Fabien Guidez, Sarah Parks, Henna Wong, Jelena V. Jovanovic, Ashley Mays, Amanda F. Gilkes, Kenneth I. Mills, Marie-Claude Guillemin, Robin M. Hobbs, Pier Paolo Pandolfi, Hugues de Thé, Ellen Solomon, and David Grimwade
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18694–18699. Published online 2007 November 13. doi: 10.1073/pnas.0704433104.
PMCID: PMC2141839
Side population in human uterine myometrium displays phenotypic and functional characteristics of myometrial stem cells
Masanori Ono, Tetsuo Maruyama, Hirotaka Masuda, Takashi Kajitani, Takashi Nagashima, Toru Arase, Mamoru Ito, Kuniaki Ohta, Hiroshi Uchida, Hironori Asada, Yasunori Yoshimura, Hideyuki Okano, and Yumi Matsuzaki
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18700–18705. Published online 2007 November 14. doi: 10.1073/pnas.0704472104.
PMCID: PMC2141840
Microbiology
The W148L substitution in the Escherichia coli ammonium channel AmtB increases flux and indicates that the substrate is an ion
Rebecca N. Fong, Kwang-Seo Kim, Corinne Yoshihara, William B. Inwood, and Sydney Kustu
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18706–18711. Published online 2007 November 12. doi: 10.1073/pnas.0709267104.
PMCID: PMC2141841
B1500, a small membrane protein, connects the two-component systems EvgS/EvgA and PhoQ/PhoP in Escherichia coli
Yoko Eguchi, Junji Itou, Masatake Yamane, Ryo Demizu, Fumiyuki Yamato, Ario Okada, Hirotada Mori, Akinori Kato, and Ryutaro Utsumi
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18712–18717. Published online 2007 November 12. doi: 10.1073/pnas.0705768104.
PMCID: PMC2141842
Bimolecular complementation reveals that glycoproteins gB and gH/gL of herpes simplex virus interact with each other during cell fusion
Doina Atanasiu, J. Charles Whitbeck, Tina M. Cairns, Brigid Reilly, Gary H. Cohen, and Roselyn J. Eisenberg
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18718–18723. Published online 2007 November 14. doi: 10.1073/pnas.0707452104.
PMCID: PMC2141843
Poxvirus DNA primase
Frank S. De Silva, Whitney Lewis, Peter Berglund, Eugene V. Koonin, and Bernard Moss
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18724–18729. Published online 2007 November 13. doi: 10.1073/pnas.0709276104.
PMCID: PMC2141844
Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens
Jun Xu, Charles W. Saunders, Ping Hu, Raymond A. Grant, Teun Boekhout, Eiko E. Kuramae, James W. Kronstad, Yvonne M. DeAngelis, Nancy L. Reeder, Kevin R. Johnstone, Meredith Leland, Angela M. Fieno, William M. Begley, Yiping Sun, Martin P. Lacey, Tanuja Chaudhary, Thomas Keough, Lien Chu, Russell Sears, Bo Yuan, and Thomas L. Dawson, Jr
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18730–18735. Published online 2007 November 13. doi: 10.1073/pnas.0706756104.
PMCID: PMC2141845
Neuroscience
Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice
Roberto C. Agís-Balboa, Graziano Pinna, Fabio Pibiri, Bashkim Kadriu, Erminio Costa, and Alessandro Guidotti
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18736–18741. Published online 2007 November 14. doi: 10.1073/pnas.0709419104.
PMCID: PMC2141846
S-nitrosylation of peroxiredoxin 2 promotes oxidative stress-induced neuronal cell death in Parkinson's disease
Jianguo Fang, Tomohiro Nakamura, Dong-Hyung Cho, Zezong Gu, and Stuart A. Lipton
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18742–18747. Published online 2007 November 14. doi: 10.1073/pnas.0705904104.
PMCID: PMC2141847
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage
Hossein Aleyasin, Maxime W. C. Rousseaux, Maryam Phillips, Raymond H. Kim, Ross J. Bland, Steve Callaghan, Ruth S. Slack, Matthew J. During, Tak W. Mak, and David S. Park
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18748–18753. Published online 2007 November 14. doi: 10.1073/pnas.0709379104.
PMCID: PMC2141848
Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease
Anamitra Ghosh, Avik Roy, Xiaojuan Liu, Jeffrey H. Kordower, Elliott J. Mufson, Dean M. Hartley, Sankar Ghosh, R. Lee Mosley, Howard E. Gendelman, and Kalipada Pahan
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18754–18759. Published online 2007 November 13. doi: 10.1073/pnas.0704908104.
PMCID: PMC2141849
Selective changes of resting-state networks in individuals at risk for Alzheimer's disease
Christian Sorg, Valentin Riedl, Mark Mühlau, Vince D. Calhoun, Tom Eichele, Leonhard Läer, Alexander Drzezga, Hans Förstl, Alexander Kurz, Claus Zimmer, and Afra M. Wohlschläger
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18760–18765. Published online 2007 November 14. doi: 10.1073/pnas.0708803104.
PMCID: PMC2141850
Visual grouping in human parietal cortex
Yaoda Xu and Marvin M. Chun
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18766–18771. Published online 2007 November 12. doi: 10.1073/pnas.0705618104.
PMCID: PMC2141851
Natural stimuli evoke dynamic sequences of states in sensory cortical ensembles
Lauren M. Jones, Alfredo Fontanini, Brian F. Sadacca, Paul Miller, and Donald B. Katz
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18772–18777. Published online 2007 November 13. doi: 10.1073/pnas.0705546104.
PMCID: PMC2141852
Sleep transforms the cerebral trace of declarative memories
Steffen Gais, Geneviève Albouy, Mélanie Boly, Thien Thanh Dang-Vu, Annabelle Darsaud, Martin Desseilles, Géraldine Rauchs, Manuel Schabus, Virginie Sterpenich, Gilles Vandewalle, Pierre Maquet, and Philippe Peigneux
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18778–18783. Published online 2007 November 13. doi: 10.1073/pnas.0705454104.
PMCID: PMC2141853
AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity
Susumu Tomita, R. Keith Byrd, Nathalie Rouach, Camilla Bellone, Angela Venegas, Jessica L. O'Brien, Kwang S. Kim, Olav Olsen, Roger A. Nicoll, and David S. Bredt
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18784–18788. Published online 2007 November 13. doi: 10.1073/pnas.0708970104.
PMCID: PMC2141854
Physiology
Developmental regulation of hypoxia-inducible factor 1 and prolyl-hydroxylases in pulmonary vascular smooth muscle cells
Ernesto R. Resnik, Jean M. Herron, Shu-Chen Lyu, and David N. Cornfield
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18789–18794. Published online 2007 November 13. doi: 10.1073/pnas.0706019104.
PMCID: PMC2141855
Plant Biology
The developmental selector AS1 is an evolutionarily conserved regulator of the plant immune response
Pedro L. Nurmberg, Kirsten A. Knox, Byung-Wook Yun, Peter C. Morris, Reza Shafiei, Andrew Hudson, and Gary J. Loake
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18795–18800. Published online 2007 November 14. doi: 10.1073/pnas.0705586104.
PMCID: PMC2141856
The shoot meristem identity gene TFL1 is involved in flower development and trafficking to the protein storage vacuole
Eun Ju Sohn, Marcela Rojas-Pierce, Songqin Pan, Clay Carter, Antonio Serrano-Mislata, Francisco Madueño, Enrique Rojo, Marci Surpin, and Natasha V. Raikhel
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18801–18806. Published online 2007 November 14. doi: 10.1073/pnas.0708236104.
PMCID: PMC2141857
An Arabidopsis thaliana high-affinity molybdate transporter required for efficient uptake of molybdate from soil
Hajime Tomatsu, Junpei Takano, Hideki Takahashi, Akiko Watanabe-Takahashi, Nakako Shibagaki, and Toru Fujiwara
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18807–18812. Published online 2007 November 14. doi: 10.1073/pnas.0706373104.
PMCID: PMC2141858
Separate functions for nuclear and cytoplasmic cryptochrome 1 during photomorphogenesis of Arabidopsis seedlings
Guosheng Wu and Edgar P. Spalding
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18813–18818. Published online 2007 November 14. doi: 10.1073/pnas.0705082104.
PMCID: PMC2141859
Circadian rhythms of superhelical status of DNA in cyanobacteria
Mark A. Woelfle, Yao Xu, Ximing Qin, and Carl Hirschie Johnson
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18819–18824. Published online 2007 November 13. doi: 10.1073/pnas.0706069104.
PMCID: PMC2141860
NPY1, a BTB-NPH3-like protein, plays a critical role in auxin-regulated organogenesis in Arabidopsis
Youfa Cheng, Genji Qin, Xinhua Dai, and Yunde Zhao
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18825–18829. Published online 2007 November 13. doi: 10.1073/pnas.0708506104.
PMCID: PMC2141861
A distinct mechanism regulating a pollen-specific guanine nucleotide exchange factor for the small GTPase Rop in Arabidopsis thaliana
Yan Zhang and Sheila McCormick
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18830–18835. Published online 2007 November 13. doi: 10.1073/pnas.0705874104.
PMCID: PMC2141862
Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana
Frank Hartung, Stefanie Suer, and Holger Puchta
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18836–18841. Published online 2007 November 13. doi: 10.1073/pnas.0705998104.
PMCID: PMC2141863
Regulation of tradeoffs between plant defenses against pathogens with different lifestyles
Steven H. Spoel, Jessica S. Johnson, and Xinnian Dong
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18842–18847. Published online 2007 November 12. doi: 10.1073/pnas.0708139104.
PMCID: PMC2141864
Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism
Roland Jenrich, Inga Trompetter, Søren Bak, Carl Erik Olsen, Birger Lindberg Møller, and Markus Piotrowski
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18848–18853. Published online 2007 November 14. doi: 10.1073/pnas.0709315104.
PMCID: PMC2141865
Psychology
Inequity responses of monkeys modified by effort
Megan van Wolkenten, Sarah F. Brosnan, and Frans B. M. de Waal
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18854–18859. Published online 2007 November 13. doi: 10.1073/pnas.0707182104.
PMCID: PMC2141866
Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism
Avshalom Caspi, Benjamin Williams, Julia Kim-Cohen, Ian W. Craig, Barry J. Milne, Richie Poulton, Leonard C. Schalkwyk, Alan Taylor, Helen Werts, and Terrie E. Moffitt
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18860–18865. Published online 2007 November 5. doi: 10.1073/pnas.0704292104.
PMCID: PMC2141867
Sustainability Science
From the Cover:
Contributions to accelerating atmospheric CO2 growth from economic activity, carbon intensity, and efficiency of natural sinks
Josep G. Canadell, Corinne Le Quéré, Michael R. Raupach, Christopher B. Field, Erik T. Buitenhuis, Philippe Ciais, Thomas J. Conway, Nathan P. Gillett, R. A. Houghton, and Gregg Marland
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18866–18870. Published online 2007 October 25. doi: 10.1073/pnas.0702737104.
PMCID: PMC2141868
Sustainable and efficient biohydrogen production via electrohydrogenesis
Shaoan Cheng and Bruce E. Logan
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18871–18873. Published online 2007 November 13. doi: 10.1073/pnas.0706379104.
PMCID: PMC2141869
Social Sciences
Economic Sciences
Optimal savings and the value of population
Kenneth J. Arrow, Alain Bensoussan, Qi Feng, and Suresh P. Sethi
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18421–18426. Published online 2007 November 5. doi: 10.1073/pnas.0708030104.
PMCID: PMC2141792
Corrections
Correction for Sales-Pardo et al., Extracting the hierarchical organization of complex systems
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18874. Published online 2007 November 12. doi: 10.1073/pnas.0709460104.
PMCID: PMC2141870
Corrects: Marta Sales-Pardo, et al. Extracting the hierarchical organization of complex systems. Proc Natl Acad Sci U S A. 2007 September 25; 104(39): 15224–15229.
Correction for Estébanez-Perpiñá et al., A surface on the androgen receptor that allosterically regulates coactivator binding
Proc Natl Acad Sci U S A. 2007 November 20; 104(47): 18874. Published online 2007 November 12. doi: 10.1073/pnas.0709913104.
PMCID: PMC2141871
Corrects: Eva Estébanez-Perpiñá, et al. A surface on the androgen receptor that allosterically regulates coactivator binding. Proc Natl Acad Sci U S A. 2007 October 9; 104(41): 16074–16079.
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