| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 October 2; 104(40): 15585–15586. doi: 10.1073/iti4007104.PMCID: PMC2000417 Commentaries Crystallography gets the jump on the enzymologists David P. Ballou PMCID: PMC2000423 Sizing up life and death Karl J. Niklas PMCID: PMC2000428 Perspective What a difference a decade makes: Insights into translesion DNA synthesis Wei Yang and Roger Woodgate PMCID: PMC2000391 Physical Sciences Applied Physical Sciences Finite deformation mechanics in buckled thin films on compliant supports Hanqing Jiang, Dahl-Young Khang, Jizhou Song, Yugang Sun, Yonggang Huang, and John A. Rogers PMCID: PMC2000418 Chemistry Exhaled methyl nitrate as a noninvasive marker of hyperglycemia in type 1 diabetes B. J. Novak, D. R. Blake, S. Meinardi, F. S. Rowland, A. Pontello, D. M. Cooper, and P. R. Galassetti PMCID: PMC1994136 A functional single-molecule binding assay via force spectroscopy Yi Cao, M. M. Balamurali, Deepak Sharma, and Hongbin Li PMCID: PMC2000387 Engineering From the Cover:
Physical plasticity of the nucleus in stem cell differentiation J. David Pajerowski, Kris Noel Dahl, Franklin L. Zhong, Paul J. Sammak, and Dennis E. Discher PMCID: PMC2000408 A model for the role of integrins in flow induced mechanotransduction in osteocytes Yilin Wang, Laoise M. McNamara, Mitchell B. Schaffler, and Sheldon Weinbaum PMCID: PMC2000405 Biological Sciences Anthropology Heritability of ultimatum game responder behavior Björn Wallace, David Cesarini, Paul Lichtenstein, and Magnus Johannesson PMCID: PMC1997219 Biochemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p Daqi Tu, Wei Li, Yihong Ye, and Axel T. Brunger PMCID: PMC2000413 DNA sequence- and conformation-directed positioning of nucleosomes by chromatin-remodeling complexes Karsten Rippe, Anna Schrader, Philipp Riede, Ralf Strohner, Elisabeth Lehmann, and Gernot Längst PMCID: PMC2000439 Structural diversity in twin-arginine signal peptide-binding proteins Julien Maillard, Chris A. E. M. Spronk, Grant Buchanan, Verity Lyall, David J. Richardson, Tracy Palmer, Geerten W. Vuister, and Frank Sargent PMCID: PMC2000414 Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi Angie R. Purvis, Julia Gross, Luke T. Dang, Ren-Huai Huang, Milan Kapadia, R. Reid Townsend, and J. Evan Sadler PMCID: PMC1994133 Alterations in an inositol phosphate code through synergistic activation of a G protein and inositol phosphate kinases James C. Otto, Patrick Kelly, Shean-Tai Chiou, and John D. York PMCID: PMC1994134 Molecular basis for passive immunotherapy of Alzheimer's disease Anna S. Gardberg, Lezlee T. Dice, Susan Ou, Rebecca L. Rich, Elizabeth Helmbrecht, Jan Ko, Ronald Wetzel, David G. Myszka, Paul H. Patterson, and Chris Dealwis PMCID: PMC1994138 Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis Sabyasachi Sanyal, Ann Båvner, Anna Haroniti, Lisa-Mari Nilsson, Thomas Lundåsen, Stefan Rehnmark, Michael Robin Witt, Curt Einarsson, Iannis Talianidis, Jan-åke Gustafsson, and Eckardt Treuter PMCID: PMC2000397 How the regulatory protein, IF1, inhibits F1-ATPase from bovine mitochondria Jonathan R. Gledhill, Martin G. Montgomery, Andrew G. W. Leslie, and John E. Walker PMCID: PMC1994141 Biophysics A functional single-molecule binding assay via force spectroscopy Yi Cao, M. M. Balamurali, Deepak Sharma, and Hongbin Li PMCID: PMC2000387 Toward high-resolution prediction and design of transmembrane helical protein structures P. Barth, J. Schonbrun, and D. Baker PMCID: PMC2000396 Load fluctuations drive actin network growth Joshua W. Shaevitz and Daniel A. Fletcher PMCID: PMC2000411 Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation Dharmaraj Samuel, Hong Cheng, Paul W. Riley, Adrian A. Canutescu, Chandrasekaran Nagaswami, John W. Weisel, Zimei Bu, Peter N. Walsh, and Heinrich Roder PMCID: PMC1987390 Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution Janina Buck, Boris Fürtig, Jonas Noeske, Jens Wöhnert, and Harald Schwalbe PMCID: PMC2000436 Direct observation of ligand transfer and bond formation in cytochrome c oxidase by using mid-infrared chirped-pulse upconversion Johanne Treuffet, Kevin J. Kubarych, Jean-Christophe Lambry, Eric Pilet, Jean-Baptiste Masson, Jean-Louis Martin, Marten H. Vos, Manuel Joffre, and Antigoni Alexandrou PMCID: PMC2000433 A study of communication pathways in methionyl- tRNA synthetase by molecular dynamics simulations and structure network analysis Amit Ghosh and Saraswathi Vishveshwara PMCID: PMC2000407 Φ-Value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy Philipp Neudecker, Arash Zarrine-Afsar, Alan R. Davidson, and Lewis E. Kay PMCID: PMC2000424 Atomic-level structural and functional model of a bacterial photosynthetic membrane vesicle Melih K. Şener, John D. Olsen, C. Neil Hunter, and Klaus Schulten PMCID: PMC2000399 Light-triggered β-hairpin folding and unfolding Tobias E. Schrader, Wolfgang J. Schreier, Thorben Cordes, Florian O. Koller, Galina Babitzki, Robert Denschlag, Christian Renner, Markus Löweneck, Shou-Liang Dong, Luis Moroder, Paul Tavan, and Wolfgang Zinth PMCID: PMC1993841 Cell Biology CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature Zhenhua Miao, Kathryn E. Luker, Bretton C. Summers, Rob Berahovich, Mahaveer S. Bhojani, Alnawaz Rehemtulla, Celina G. Kleer, Jeffrey J. Essner, Aidas Nasevicius, Gary D. Luker, Maureen C. Howard, and Thomas J. Schall PMCID: PMC1994579 Chromatin fine structure of the c-MYC insulator element/DNase I-hypersensitive site I is not preserved during mitosis Jun-ichiro Komura, Hironobu Ikehata, and Tetsuya Ono PMCID: PMC2000435 Circadian control by the reduction/oxidation pathway: Catalase represses light-dependent clock gene expression in the zebrafish Jun Hirayama, Sehyung Cho, and Paolo Sassone-Corsi PMCID: PMC2000381 The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels Pascale Daran-Lapujade, Sergio Rossell, Walter M. van Gulik, Marijke A. H. Luttik, Marco J. L. de Groot, Monique Slijper, Albert J. R. Heck, Jean-Marc Daran, Johannes H. de Winde, Hans V. Westerhoff, Jack T. Pronk, and Barbara M. Bakker PMCID: PMC2000426 Suppression of p53-dependent senescence by the JNK signal transduction pathway Madhumita Das, Feng Jiang, Hayla K. Sluss, Chao Zhang, Kevan M. Shokat, Richard A. Flavell, and Roger J. Davis PMCID: PMC2000443 Developmental Biology From the Cover:
Physical plasticity of the nucleus in stem cell differentiation J. David Pajerowski, Kris Noel Dahl, Franklin L. Zhong, Paul J. Sammak, and Dennis E. Discher PMCID: PMC2000408 The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left–right patterning Anja Beckers, Leonie Alten, Christoph Viebahn, Philipp Andre, and Achim Gossler PMCID: PMC2000419 A Myc–Groucho complex integrates EGF and Notch signaling to regulate neural development Amir Orian, Jeffrey J. Delrow, Alicia E. Rosales Nieves, Mona Abed, David Metzger, Ze'ev Paroush, Robert N. Eisenman, and Susan M. Parkhurst PMCID: PMC2000393 Ecology From the Cover:
Allometric scaling of plant life history Núria Marbà, Carlos M. Duarte, and Susana Agustí PMCID: PMC1989662 Environmental Sciences Aquatic eutrophication promotes pathogenic infection in amphibians Pieter T. J. Johnson, Jonathan M. Chase, Katherine L. Dosch, Richard B. Hartson, Jackson A. Gross, Don J. Larson, Daniel R. Sutherland, and Stephen R. Carpenter PMCID: PMC2000446 Evolution From the Cover:
On the origin of smallpox: Correlating variola phylogenics with historical smallpox records Yu Li, Darin S. Carroll, Shea N. Gardner, Matthew C. Walsh, Elizabeth A. Vitalis, and Inger K. Damon PMCID: PMC2000395 Hybrid vigor between native and introduced salamanders raises new challenges for conservation Benjamin M. Fitzpatrick and H. Bradley Shaffer PMCID: PMC2000440 Trait changes in a harvested population are driven by a dynamic tug-of-war between natural and harvest selection Eric Edeline, Stephanie M. Carlson, Leif C. Stige, Ian J. Winfield, Janice M. Fletcher, J. Ben James, Thrond O. Haugen, L. Asbjørn Vøllestad, and Nils C. Stenseth PMCID: PMC2000386 Genetics MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B Muller Fabbri, Ramiro Garzon, Amelia Cimmino, Zhongfa Liu, Nicola Zanesi, Elisa Callegari, Shujun Liu, Hansjuerg Alder, Stefan Costinean, Cecilia Fernandez-Cymering, Stefano Volinia, Gulnur Guler, Carl D. Morrison, Kenneth K. Chan, Guido Marcucci, George A. Calin, Kay Huebner, and Carlo M. Croce PMCID: PMC2000384 A quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species Nelson B. Freimer, Susan K. Service, Roel A. Ophoff, Anna J. Jasinska, Kevin McKee, Amelie Villeneuve, Alexandre Belisle, Julia N. Bailey, Sherry E. Breidenthal, Matthew J. Jorgensen, J. John Mann, Rita M. Cantor, Ken Dewar, and Lynn A. Fairbanks PMCID: PMC1987389 Immunology Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge Rui He, Michiko K. Oyoshi, Haoli Jin, and Raif S. Geha PMCID: PMC2000444 Ulcerative colitis and autoimmunity induced by loss of myeloid αv integrins Adam Lacy-Hulbert, Aileen M. Smith, Hamid Tissire, Marc Barry, Denise Crowley, Roderick T. Bronson, Jürgen T. Roes, John S. Savill, and Richard O. Hynes PMCID: PMC1994135 Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation Akira Togayachi, Yuko Kozono, Hiroyasu Ishida, Sumie Abe, Nami Suzuki, Yuki Tsunoda, Kozue Hagiwara, Atsushi Kuno, Takashi Ohkura, Nobuo Sato, Takashi Sato, Jun Hirabayashi, Yuzuru Ikehara, Kouichi Tachibana, and Hisashi Narimatsu PMCID: PMC2000437 Medical Sciences Exhaled methyl nitrate as a noninvasive marker of hyperglycemia in type 1 diabetes B. J. Novak, D. R. Blake, S. Meinardi, F. S. Rowland, A. Pontello, D. M. Cooper, and P. R. Galassetti PMCID: PMC1994136 PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium falciparum malaria Johan Normark, Daniel Nilsson, Ulf Ribacke, Gerhard Winter, Kirsten Moll, Craig E. Wheelock, Justus Bayarugaba, Fred Kironde, Thomas G. Egwang, Qijun Chen, Björn Andersson, and Mats Wahlgren PMCID: PMC1994139 Proinsulin maturation, misfolding, and proteotoxicity Ming Liu, Israel Hodish, Christopher J. Rhodes, and Peter Arvan PMCID: PMC2000385 Estradiol-17β regulates mouse uterine epithelial cell proliferation through insulin-like growth factor 1 signaling Liyin Zhu and Jeffrey W. Pollard PMCID: PMC2000402 IκB kinase α kinase activity is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells Yixue Cao, Jun-li Luo, and Michael Karin PMCID: PMC2000410 From the Cover:
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids Prescott G. Woodruff, Homer A. Boushey, Gregory M. Dolganov, Chris S. Barker, Yee Hwa Yang, Samantha Donnelly, Almut Ellwanger, Sukhvinder S. Sidhu, Trang P. Dao-Pick, Carlos Pantoja, David J. Erle, Keith R. Yamamoto, and John V. Fahy PMCID: PMC2000427 Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopy Thomas D. Wang, George Triadafilopoulos, James M. Crawford, Lisa R. Dixon, Tarun Bhandari, Peyman Sahbaie, Shai Friedland, Roy Soetikno, and Christopher H. Contag PMCID: PMC2000401 Microbiology The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis Fabien Delaspre, Carlos G. Nieto Peñalver, Olivier Saurel, Patrick Kiefer, Emmanuel Gras, Alain Milon, Christian Boucher, Stéphane Genin, and Julia A. Vorholt PMCID: PMC2000445 From the Cover:
Social cheating in Pseudomonas aeruginosa quorum sensing Kelsi M. Sandoz, Shelby M. Mitzimberg, and Martin Schuster PMCID: PMC2000394 Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion Rhoel R. Dinglasan, Aditi Alaganan, Anil K. Ghosh, Akio Saito, Toin H. van Kuppevelt, and Marcelo Jacobs-Lorena PMCID: PMC2000438 3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili Sophie Helaine, David H. Dyer, Xavier Nassif, Vladimir Pelicic, and Katrina T. Forest PMCID: PMC2000383 Neuroscience Musicians have enhanced subcortical auditory and audiovisual processing of speech and music Gabriella Musacchia, Mikko Sams, Erika Skoe, and Nina Kraus PMCID: PMC2000431 FOXO and insulin signaling regulate sensitivity of the circadian clock to oxidative stress Xiangzhong Zheng, Zhaohai Yang, Zhifeng Yue, John D. Alvarez, and Amita Sehgal PMCID: PMC2000406 Circadian regulation of insect olfactory learning Susan Decker, Shannon McConnaughey, and Terry L. Page PMCID: PMC2000404 In vivo mouse inferior olive neurons exhibit heterogeneous subthreshold oscillations and spiking patterns S. Khosrovani, R. S. Van Der Giessen, C. I. De Zeeuw, and M. T. G. De Jeu PMCID: PMC2000380 Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons Dyke P. McEwen, Robert K. Koenekoop, Hemant Khanna, Paul M. Jenkins, Irma Lopez, Anand Swaroop, and Jeffrey R. Martens PMCID: PMC2000398 Posttetanic potentiation critically depends on an enhanced Ca2+ sensitivity of vesicle fusion mediated by presynaptic PKC Natalya Korogod, Xuelin Lou, and Ralf Schneggenburger PMCID: PMC2000442 Increased motion and travel, rather than stable docking, characterize the last moments before secretory granule fusion Vadim E. Degtyar, Miriam W. Allersma, Daniel Axelrod, and Ronald W. Holz PMCID: PMC2000388 Intensive training in adults refines A1 representations degraded in an early postnatal critical period Xiaoming Zhou and Michael M. Merzenich PMCID: PMC1994137 Physiology A model for the role of integrins in flow induced mechanotransduction in osteocytes Yilin Wang, Laoise M. McNamara, Mitchell B. Schaffler, and Sheldon Weinbaum PMCID: PMC2000405 Plant Biology A chloroplast cyclophilin functions in the assembly and maintenance of photosystem II in Arabidopsis thaliana Aigen Fu, Zengyong He, Hye Sun Cho, Amparo Lima, Bob B. Buchanan, and Sheng Luan PMCID: PMC2000425 Regulation of SHOOT MERISTEMLESS genes via an upstream-conserved noncoding sequence coordinates leaf development Naoyuki Uchida, Brad Townsley, Kook-Hyun Chung, and Neelima Sinha PMCID: PMC2000400 A protein phosphorylation/dephosphorylation network regulates a plant potassium channel Sung Chul Lee, Wen-Zhi Lan, Beom-Gi Kim, Legong Li, Yong Hwa Cheong, Girdhar K. Pandey, Guihua Lu, Bob B. Buchanan, and Sheng Luan PMCID: PMC2000415 Social Sciences Anthropology Spatial gradients in Clovis-age radiocarbon dates across North America suggest rapid colonization from the north Marcus J. Hamilton and Briggs Buchanan PMCID: PMC2000382 Economic Sciences Heritability of ultimatum game responder behavior Björn Wallace, David Cesarini, Paul Lichtenstein, and Magnus Johannesson PMCID: PMC1997219 Correction Correction for Scott et al., A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors PMCID: PMC2000390 Corrects: Andrew M. Scott, et al. A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors. Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4071–4076. |
