| | This journal provides immediate access to some articles. Retrospective The nine lives of Daniel E. Koshland, Jr. (1920–2007) Randy Schekman PMCID: PMC1976236 This Week in PNAS Proc Natl Acad Sci U S A. 2007 September 11; 104(37): 14545–14546. doi: 10.1073/iti3707104.PMCID: PMC1976219 Commentaries Of light and mouse embryos: Less is more Richard M. Schultz PMCID: PMC1976224 Absolute pitch: A special group of ears Dennis T. Drayna PMCID: PMC1976237 Physical Sciences Applied Physical Sciences From the Cover:
Magnetic microposts as an approach to apply forces to living cells Nathan J. Sniadecki, Alexandre Anguelouch, Michael T. Yang, Corinne M. Lamb, Zhijun Liu, Stuart B. Kirschner, Yaohua Liu, Daniel H. Reich, and Christopher S. Chen PMCID: PMC1976246 Chemistry Solvent coarse-graining and the string method applied to the hydrophobic collapse of a hydrated chain Thomas F. Miller, III, Eric Vanden-Eijnden, and David Chandler PMCID: PMC1955457 Al4H7− is a resilient building block for aluminum hydrogen cluster materials P. J. Roach, A. C. Reber, W. H. Woodward, S. N. Khanna, and A. W. Castleman, Jr. PMCID: PMC1976228 Facile O-atom insertion into C  C and C H bonds by a trinuclear copper complex designed to harness a singlet oxene Peter P.-Y. Chen, Richard B.-G. Yang, Jason C.-M. Lee, and Sunney I. Chan PMCID: PMC1976241 Distinct thermal behavior of GeO2 glass in tetrahedral, intermediate, and octahedral forms Guoyin Shen, Hanns-Peter Liermann, Stanislav Sinogeikin, Wenge Yang, Xinguo Hong, Choong-Shik Yoo, and Hyunchae Cynn PMCID: PMC1976207 Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding Jorge Chahine, Ronaldo J. Oliveira, Vitor B. P. Leite, and Jin Wang PMCID: PMC1976201 Environmental Sciences Impact of anthropogenic atmospheric nitrogen and sulfur deposition on ocean acidification and the inorganic carbon system Scott C. Doney, Natalie Mahowald, Ivan Lima, Richard A. Feely, Fred T. Mackenzie, Jean-Francois Lamarque, and Phil J. Rasch PMCID: PMC1965482 Sustainability Science Impact of anthropogenic atmospheric nitrogen and sulfur deposition on ocean acidification and the inorganic carbon system Scott C. Doney, Natalie Mahowald, Ivan Lima, Richard A. Feely, Fred T. Mackenzie, Jean-Francois Lamarque, and Phil J. Rasch PMCID: PMC1965482 Biological Sciences Biochemistry A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist W. David Tolbert, Jennifer Daugherty, ChongFeng Gao, Qian Xie, Cindy Miranti, Ermanno Gherardi, George Vande Woude, and H. Eric Xu PMCID: PMC1965485 Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template Ching-Hsuan Tsai, Jingyang Chen, and Jack W. Szostak PMCID: PMC1976233 The self-inhibited structure of full-length PCSK9 at 1.9 Å reveals structural homology with resistin within the C-terminal domain Eric N. Hampton, Mark W. Knuth, Jun Li, Jennifer L. Harris, Scott A. Lesley, and Glen Spraggon PMCID: PMC1976225 Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells Chandima Abeywickrama, Hiroko Matsuda, Steffen Jockusch, Jilin Zhou, Young P. Jang, Bi-Xing Chen, Yasuhiro Itagaki, Bernard F. Erlanger, Koji Nakanishi, Nicholas J. Turro, and Janet R. Sparrow PMCID: PMC1976245 Patterns of damage in genomic DNA sequences from a Neandertal Adrian W. Briggs, Udo Stenzel, Philip L. F. Johnson, Richard E. Green, Janet Kelso, Kay Prüfer, Matthias Meyer, Johannes Krause, Michael T. Ronan, Michael Lachmann, and Svante Pääbo PMCID: PMC1976210 Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon Michiyo Mizuuchi, Phoebe A. Rice, Simon J. Wardle, David B. Haniford, and Kiyoshi Mizuuchi PMCID: PMC1964541 The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis Emmanuelle Sacco, Adrian Suarez Covarrubias, Helen M. O'Hare, Paul Carroll, Nathalie Eynard, T. Alwyn Jones, Tanya Parish, Mamadou Daffé, Kristina Bäckbro, and Annaïk Quémard PMCID: PMC1976197 Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases Jason Stagno, Inna Aphasizheva, Ruslan Aphasizhev, and Hartmut Luecke PMCID: PMC1976215 Crystal structure of human mitoNEET reveals distinct groups of iron–sulfur proteins Jinzhong Lin, Tao Zhou, Keqiong Ye, and Jinfeng Wang PMCID: PMC1976232 Biophysics Solvent coarse-graining and the string method applied to the hydrophobic collapse of a hydrated chain Thomas F. Miller, III, Eric Vanden-Eijnden, and David Chandler PMCID: PMC1955457 Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding Jorge Chahine, Ronaldo J. Oliveira, Vitor B. P. Leite, and Jin Wang PMCID: PMC1976201 From the Cover:
Real-time observations of single bacteriophage λ DNA ejections in vitro Paul Grayson, Lin Han, Tabita Winther, and Rob Phillips PMCID: PMC1976217 Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy Thomas Hellerer, Claes Axäng, Christian Brackmann, Per Hillertz, Marc Pilon, and Annika Enejder PMCID: PMC1976189 Automated de novo prediction of native-like RNA tertiary structures Rhiju Das and David Baker PMCID: PMC1955458 Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism Bhupesh Taneja, Bernhard Schnurr, Alexei Slesarev, John F. Marko, and Alfonso Mondragón PMCID: PMC1976220 Spectroscopic validation of the pentameric structure of phospholamban Nathaniel J. Traaseth, Raffaello Verardi, Kurt D. Torgersen, Christine B. Karim, David D. Thomas, and Gianluigi Veglia PMCID: PMC1976191 Temperature-dependent heme kinetics with nonexponential binding and barrier relaxation in the absence of protein conformational substates Xiong Ye, Dan Ionascu, Florin Gruia, Anchi Yu, Abdelkrim Benabbas, and Paul M. Champion PMCID: PMC1976205 Cell Biology Mei4p coordinates the onset of meiosis I by regulating cdc25+ in fission yeast Yuko Murakami-Tonami, Chisato Yamada-Namikawa, Akiko Tochigi, Norio Hasegawa, Hisae Kojima, Mitoshi Kunimatsu, Makoto Nakanishi, and Hiroshi Murakami PMCID: PMC1976235 Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization Johanna I. Partanen, Anni I. Nieminen, Tomi P. Mäkelä, and Juha Klefstrom PMCID: PMC1976192 R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6 Minke E. Binnerts, Kyung-Ah Kim, Jessica M. Bright, Sejal M. Patel, Karolyn Tran, Mei Zhou, John M. Leung, Yi Liu, Woodrow E. Lomas, III, Melissa Dixon, Sophie A. Hazell, Marie Wagle, Wen-Sheng Nie, Nenad Tomasevic, Jason Williams, Xiaoming Zhan, Michael D. Levy, Walter D. Funk, and Arie Abo PMCID: PMC1965484 Centromere identity is specified by a single centromeric nucleosome in budding yeast Suzanne Furuyama and Sue Biggins PMCID: PMC1976213 Light signaling to the zebrafish circadian clock by Cryptochrome 1a T. Katherine Tamai, Lucy C. Young, and David Whitmore PMCID: PMC1976231 Developmental Biology Estrogen receptor-α expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice Yuxin Feng, David Manka, Kay-Uwe Wagner, and Sohaib A. Khan PMCID: PMC1976199 Ecology Carbon dioxide enrichment alters plant community structure and accelerates shrub growth in the shortgrass steppe Jack A. Morgan, Daniel G. Milchunas, Daniel R. LeCain, Mark West, and Arvin R. Mosier PMCID: PMC1964545 Environmental Sciences Impact of anthropogenic atmospheric nitrogen and sulfur deposition on ocean acidification and the inorganic carbon system Scott C. Doney, Natalie Mahowald, Ivan Lima, Richard A. Feely, Fred T. Mackenzie, Jean-Francois Lamarque, and Phil J. Rasch PMCID: PMC1965482 The effect of climate variations on the dynamics of pasture–livestock interactions under cooperative and noncooperative management Kjell Arne Brekke, Bernt Øksendal, and Nils Chr. Stenseth PMCID: PMC1976234 Evolution The evolutionary emergence of cell type-specific genes inferred from the gene expression analysis of Hydra Jung Shan Hwang, Hajime Ohyanagi, Shiho Hayakawa, Naoki Osato, Chiemi Nishimiya-Fujisawa, Kazuho Ikeo, Charles N. David, Toshitaka Fujisawa, and Takashi Gojobori PMCID: PMC1963347 Genetics Nuclear gene silencing directs reception of long-distance mRNA silencing in Arabidopsis C. A. Brosnan, N. Mitter, M. Christie, N. A. Smith, P. M. Waterhouse, and B. J. Carroll PMCID: PMC1964546 From the Cover:
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci John V. Raelson, Randall D. Little, Andreas Ruether, Hélène Fournier, Bruno Paquin, Paul Van Eerdewegh, W. E. C. Bradley, Pascal Croteau, Quynh Nguyen-Huu, Jonathan Segal, Sophie Debrus, René Allard, Philip Rosenstiel, Andre Franke, Gunnar Jacobs, Susanna Nikolaus, Jean-Michel Vidal, Peter Szego, Nathalie Laplante, Hilary F. Clark, René J. Paulussen, John W. Hooper, Tim P. Keith, Abdelmajid Belouchi, and Stefan Schreiber PMCID: PMC1965486 Immunology Specific and covalent labeling of a membrane protein with organic fluorochromes and quantum dots Roberto Bonasio, Christopher V. Carman, Enoch Kim, Peter T. Sage, Kerry R. Love, Thorsten R. Mempel, Timothy A. Springer, and Ulrich H. von Andrian PMCID: PMC1976196 Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 Frederic Sierro, Christine Biben, Laura Martínez-Muñoz, Mario Mellado, Richard M. Ransohoff, Meizhang Li, Blanche Woehl, Helen Leung, Joanna Groom, Marcel Batten, Richard P. Harvey, Carlos Martínez-A, Charles R. Mackay, and Fabienne Mackay PMCID: PMC1976222 T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-γ and IL-13 production Nobuki Hayashi, Tomohiro Yoshimoto, Kenji Izuhara, Kiyoshi Matsui, Toshio Tanaka, and Kenji Nakanishi PMCID: PMC1976243 Medical Sciences Critique of early models of the demographic impact of HIV/AIDS in sub-Saharan Africa based on contemporary empirical data from Zimbabwe Simon Gregson, Constance Nyamukapa, Ben Lopman, Phyllis Mushati, Geoffrey P. Garnett, Stephen K. Chandiwana, and Roy M. Anderson PMCID: PMC1961581 Distinct pathways of genomic progression to benign and malignant tumors of the liver Aaron D. Tward, Kirk D. Jones, Stephen Yant, Siu Tim Cheung, Sheung Tat Fan, Xin Chen, Mark A. Kay, Rong Wang, and J. Michael Bishop PMCID: PMC1964540 Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production Kathryn X. Wang, Yufang Shi, and David T. Denhardt PMCID: PMC1976226 Microbiology Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue Julia Chamot-Rooke, Benoit Rousseau, Fanny Lanternier, Guillain Mikaty, Emilie Mairey, Christian Malosse, Guy Bouchoux, Vladimir Pelicic, Luc Camoin, Xavier Nassif, and Guillaume Duménil PMCID: PMC1976187 Neuroscience Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice Masaaki Ogawa, Tsuyoshi Miyakawa, Kenji Nakamura, Jun Kitano, Kenryo Furushima, Hiroshi Kiyonari, Rika Nakayama, Kazuki Nakao, Koki Moriyoshi, and Shigetada Nakanishi PMCID: PMC1976212 From the Cover:
Dichotomy and perceptual distortions in absolute pitch ability E. Alexandra Athos, Barbara Levinson, Amy Kistler, Jason Zemansky, Alan Bostrom, Nelson Freimer, and Jane Gitschier PMCID: PMC1959403 Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments Sachiko Nishimura-Akiyoshi, Kimie Niimi, Toshiaki Nakashiba, and Shigeyoshi Itohara PMCID: PMC1964543 DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase Eva Andres-Mateos, Celine Perier, Li Zhang, Beatrice Blanchard-Fillion, Todd M. Greco, Bobby Thomas, Han Seok Ko, Masayuki Sasaki, Harry Ischiropoulos, Serge Przedborski, Ted M. Dawson, and Valina L. Dawson PMCID: PMC1976193 Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)α and ERβ ligand treatment Seema Tiwari-Woodruff, Laurie Beth J. Morales, Ruri Lee, and Rhonda R. Voskuhl PMCID: PMC1976208 Mechanism of positioning the cell nucleus in vertebrate photoreceptors Motokazu Tsujikawa, Yoshihiro Omori, Janisha Biyanwila, and Jarema Malicki PMCID: PMC1976238 From the Cover:
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity Philip Van Damme, Elke Bogaert, Maarten Dewil, Nicole Hersmus, Dora Kiraly, Wendy Scheveneels, Ilse Bockx, Dries Braeken, Nathalie Verpoorten, Kristien Verhoeven, Vincent Timmerman, Paul Herijgers, Geert Callewaert, Peter Carmeliet, Ludo Van Den Bosch, and Wim Robberecht PMCID: PMC1976195 Different transmitter transients underlie presynaptic cell type specificity of GABAA,slow and GABAA,fast János Szabadics, Gábor Tamás, and Ivan Soltesz PMCID: PMC1964542 Dissociable roles of the posterior parietal and the prefrontal cortex in manipulation and monitoring processes Anne Sophie Champod and Michael Petrides PMCID: PMC1976242 Pharmacology Antipsychotic drugs reverse the disruption in prefrontal cortex function produced by NMDA receptor blockade with phencyclidine Lucila Kargieman, Noemí Santana, Guadalupe Mengod, Pau Celada, and Francesc Artigas PMCID: PMC1976198 Physiology Renal expression of parvalbumin is critical for NaCl handling and response to diuretics Hendrica Belge, Philippe Gailly, Beat Schwaller, Johannes Loffing, Huguette Debaix, Eva Riveira-Munoz, Renaud Beauwens, Jean-Pierre Devogelaer, Joost G. Hoenderop, René J. Bindels, and Olivier Devuyst PMCID: PMC1976223 SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase Ilwola Mattagajasingh, Cuk-Seong Kim, Asma Naqvi, Tohru Yamamori, Timothy A. Hoffman, Saet-Byel Jung, Jeremy DeRicco, Kenji Kasuno, and Kaikobad Irani PMCID: PMC1976244 Plant Biology Plant disease susceptibility conferred by a “resistance” gene Jennifer M. Lorang, Teresa A. Sweat, and Thomas J. Wolpert PMCID: PMC1976202 The small interfering RNA production pathway is required for shoot meristem initiation in rice Hiroshi Nagasaki, Jun-ichi Itoh, Katsunobu Hayashi, Ken-ichiro Hibara, Namiko Satoh-Nagasawa, Misuzu Nosaka, Motohiro Mukouhata, Motoyuki Ashikari, Hidemi Kitano, Makoto Matsuoka, Yasuo Nagato, and Yutaka Sato PMCID: PMC1976227 Population Biology Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome A. Khan, B. Fux, C. Su, J. P. Dubey, M. L. Darde, J. W. Ajioka, B. M. Rosenthal, and L. D. Sibley PMCID: PMC1965483 Social Sciences Economic Sciences The effect of climate variations on the dynamics of pasture–livestock interactions under cooperative and noncooperative management Kjell Arne Brekke, Bernt Øksendal, and Nils Chr. Stenseth PMCID: PMC1976234 Social Sciences Critique of early models of the demographic impact of HIV/AIDS in sub-Saharan Africa based on contemporary empirical data from Zimbabwe Simon Gregson, Constance Nyamukapa, Ben Lopman, Phyllis Mushati, Geoffrey P. Garnett, Stephen K. Chandiwana, and Roy M. Anderson PMCID: PMC1961581 Correction Correction for Cisse et al., Single-Molecule Chemistry and Biology Special Feature: Fueling protein–DNA interactions inside porous nanocontainers PMCID: PMC1976206 Corrects: Ibrahim Cisse, et al. Fueling protein–DNA interactions inside porous nanocontainers. Proc Natl Acad Sci U S A. 2007 July 31; 104(31): 12646–12650. |
