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Volume 35(6);  March 2007
Molecular Biology
The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function
Giacomo Cattaruzzi, Sandro Altamura, Michela A. Tessari, Alessandra Rustighi, Vincenzo Giancotti, Carlo Pucillo, and Guidalberto Manfioletti
Nucleic Acids Res. 2007 March; 35(6): 1751–1760. Published online 2007 February 25. doi: 10.1093/nar/gkl1106.
PMCID: PMC1874589
Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes
Brian Boer, Janel Kopp, Sunil Mallanna, Michelle Desler, Harini Chakravarthy, Phillip J. Wilder, Cory Bernadt, and Angie Rizzino
Nucleic Acids Res. 2007 March; 35(6): 1773–1786. Published online 2007 February 25. doi: 10.1093/nar/gkm059.
PMCID: PMC1874607
Mlc regulation of Salmonella pathogenicity island I gene expression via hilE repression
Sangyong Lim, Jiae Yun, Hyunjin Yoon, Chehwee Park, Boowon Kim, Byeonghwa Jeon, Dongho Kim, and Sangryeol Ryu
Nucleic Acids Res. 2007 March; 35(6): 1822–1832. Published online 2007 February 28. doi: 10.1093/nar/gkm060.
PMCID: PMC1874608
Switched alternative splicing of oncogene CoAA during embryonal carcinoma stem cell differentiation
Zheqiong Yang, Yang Sui, Shiqin Xiong, Sean S. Liour, Andrew C. Phillips, and Lan Ko
Nucleic Acids Res. 2007 March; 35(6): 1919–1932. Published online 2007 March 1. doi: 10.1093/nar/gkl1092.
PMCID: PMC1874587
Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation
Ester Valls, Noemí Blanco-García, Naiara Aquizu, David Piedra, Conchi Estarás, Xavier de la Cruz, and Marian A. Martínez-Balbás
Nucleic Acids Res. 2007 March; 35(6): 1958–1968. Published online 2007 March 6. doi: 10.1093/nar/gkl1113.
PMCID: PMC1874590
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription
Matjaz Barboric, Jasper H. N. Yik, Nadine Czudnochowski, Zhiyuan Yang, Ruichuan Chen, Xavier Contreras, Matthias Geyer, B. Matija Peterlin, and Qiang Zhou
Nucleic Acids Res. 2007 March; 35(6): 2003–2012. Published online 2007 March 6. doi: 10.1093/nar/gkm063.
PMCID: PMC1874611
Role of GAC63 in transcriptional activation mediated by β-catenin
Yong-Heng Chen, Catherine K. Yang, Meng Xia, Chen-Yin Ou, and Michael R. Stallcup
Nucleic Acids Res. 2007 March; 35(6): 2084–2092. Published online 2007 March 7. doi: 10.1093/nar/gkm095.
PMCID: PMC1874623
Cancer-derived p53 mutants suppress p53-target gene expression—potential mechanism for gain of function of mutant p53
Faina Vikhanskaya, Ming Kei Lee, Marco Mazzoletti, Massimo Broggini, and Kanaga Sabapathy
Nucleic Acids Res. 2007 March; 35(6): 2093–2104. Published online 2007 March 7. doi: 10.1093/nar/gkm099.
PMCID: PMC1874625
RNA
Alternative splicing and bioinformatic analysis of human U12-type introns
Wen-Cheng Chang, Yung-Chia Chen, Kuo-Ming Lee, and Woan-Yuh Tarn
Nucleic Acids Res. 2007 March; 35(6): 1833–1841. Published online 2007 March 1. doi: 10.1093/nar/gkm026.
PMCID: PMC1874599
An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery
A. Cléry, V. Bourguignon-Igel, C. Allmang, A. Krol, and C. Branlant
Nucleic Acids Res. 2007 March; 35(6): 1868–1884. Published online 2007 March 1. doi: 10.1093/nar/gkm066.
PMCID: PMC1874613
Studies on the function of the riboregulator 6S RNA from E. coli: RNA polymerase binding, inhibition of in vitro transcription and synthesis of RNA-directed de novo transcripts
Nina Gildehaus, Thomas Neußer, Reinhild Wurm, and Rolf Wagner
Nucleic Acids Res. 2007 March; 35(6): 1885–1896. Published online 2007 March 1. doi: 10.1093/nar/gkm085.
PMCID: PMC1874619
Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis
Andrei Yu. Kobitski, Alexander Nierth, Mark Helm, Andres Jäschke, and G. Ulrich Nienhaus
Nucleic Acids Res. 2007 March; 35(6): 2047–2059. Published online 2007 March 7. doi: 10.1093/nar/gkm072.
PMCID: PMC1874616
In vivo and in vitro investigation of bacterial type B RNase P interaction with tRNA 3′-CCA
Barbara Wegscheid and Roland K. Hartmann
Nucleic Acids Res. 2007 March; 35(6): 2060–2073. Published online 2007 March 13. doi: 10.1093/nar/gkm005.
PMCID: PMC1874595
Structural Biology
Pressure dissociation of integration host factor–DNA complexes reveals flexibility-dependent structural variation at the protein–DNA interface
Donald F. Senear, Vira Tretyachenko-Ladokhina, Michael L. Opel, Kimberly A. Aeling, G. Wesley Hatfield, Laurie M. Franklin, Reuben C. Darlington, and J.B. Alexander Ross
Nucleic Acids Res. 2007 March; 35(6): 1761–1772. Published online 2007 February 25. doi: 10.1093/nar/gkl1122.
PMCID: PMC1874591
Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins
Li-Tzu Chen, Tzu-Ping Ko, Yuan-Chih Chang, Kuei-An Lin, Chia-Seng Chang, Andrew H.-J. Wang, and Ting-Fang Wang
Nucleic Acids Res. 2007 March; 35(6): 1787–1801. Published online 2007 February 28. doi: 10.1093/nar/gkl1131.
PMCID: PMC1874592
Novel protein fold discovered in the PabI family of restriction enzymes
Ken-ichi Miyazono, Miki Watanabe, Jan Kosinski, Ken Ishikawa, Masayuki Kamo, Tatsuya Sawasaki, Koji Nagata, Janusz M. Bujnicki, Yaeta Endo, Masaru Tanokura, and Ichizo Kobayashi
Nucleic Acids Res. 2007 March; 35(6): 1908–1918. Published online 2007 March 1. doi: 10.1093/nar/gkm091.
PMCID: PMC1874622
Crystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense molecules
Ella Czarina Magat Juan, Jiro Kondo, Takeshi Kurihara, Takanori Ito, Yoshihito Ueno, Akira Matsuda, and Akio Takénaka
Nucleic Acids Res. 2007 March; 35(6): 1969–1977. Published online 2007 March 6. doi: 10.1093/nar/gkl821.
PMCID: PMC1874594
Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2′-exo (north) and 3′-exo (south) ‘locked’ templates
Melissa Maderia, Shilpa Shenoy, Que N. Van, Victor E. Marquez, and Joseph J. Barchi, Jr
Nucleic Acids Res. 2007 March; 35(6): 1978–1991. Published online 2007 March 6. doi: 10.1093/nar/gkm025.
PMCID: PMC1895885
Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding
Anwer Mujeeb, Nikolai B. Ulyanov, Stefanos Georgantis, Ivan Smirnov, Janet Chung, Tristram G. Parslow, and Thomas L. James
Nucleic Acids Res. 2007 March; 35(6): 2026–2034. Published online 2007 March 6. doi: 10.1093/nar/gkm097.
PMCID: PMC1874624
Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically
Magdalena Kaus-Drobek, Honorata Czapinska, Monika Sokołowska, Gintautas Tamulaitis, Roman H. Szczepanowski, Claus Urbanke, Virginijus Siksnys, and Matthias Bochtler
Nucleic Acids Res. 2007 March; 35(6): 2035–2046. Published online 2007 March 7. doi: 10.1093/nar/gkm064.
PMCID: PMC1874612
Survey and Summary
Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation
Ivaylo P. Ivanov and John F. Atkins
Nucleic Acids Res. 2007 March; 35(6): 1842–1858. Published online 2007 March 1. doi: 10.1093/nar/gkm035.
PMCID: PMC1874602
Genomics
Impaired expression of NER gene network in sporadic solid tumors
Mauro A. A. Castro, José C. M. Mombach, Rita M. C. de Almeida, and José C. F. Moreira
Nucleic Acids Res. 2007 March; 35(6): 1859–1867. Published online 2007 March 1. doi: 10.1093/nar/gkm061.
PMCID: PMC1874609
Beyond the 3′ end: experimental validation of extended transcript isoforms
Virginie Moucadel, Fabrice Lopez, Takeshi Ara, Philippe Benech, and Daniel Gautheret
Nucleic Acids Res. 2007 March; 35(6): 1947–1957. Published online 2007 March 4. doi: 10.1093/nar/gkm062.
PMCID: PMC1874610
EST assembly supported by a draft genome sequence: an analysis of the Chlamydomonas reinhardtii transcriptome
Monica Jain, Jeff Shrager, Elizabeth H. Harris, Renee Halbrook, Arthur R. Grossman, Charles Hauser, and Olivier Vallon
Nucleic Acids Res. 2007 March; 35(6): 2074–2083. Published online 2007 March 13. doi: 10.1093/nar/gkm081.
PMCID: PMC1874618
Chemistry
Mechanism of the formation of DNA–protein cross-links by antitumor cisplatin
Kateřina Chválová, Viktor Brabec, and Jana Kašpárková
Nucleic Acids Res. 2007 March; 35(6): 1812–1821. Published online 2007 February 28. doi: 10.1093/nar/gkm032.
PMCID: PMC1874601
Methods Online
Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes
Rory M. Watt, Jing Wang, Meikid Leong, Hsiang-fu Kung, Kathryn S.E. Cheah, Depei Liu, Antoine Danchin, and Jian-Dong Huang
Nucleic Acids Res. 2007 March; 35(6): e37. Published online 2007 January 31. doi: 10.1093/nar/gkl1158.
PMCID: PMC1874593
Motif programming: a microgene-based method for creating synthetic proteins containing multiple functional motifs
Hirohide Saito, Tamiko Minamisawa, and Kiyotaka Shiba
Nucleic Acids Res. 2007 March; 35(6): e38. Published online 2007 February 7. doi: 10.1093/nar/gkm017.
PMCID: PMC1874597
Rapid coupling of Surface Plasmon Resonance (SPR and SPRi) and ProteinChip™ based mass spectrometry for the identification of proteins in nucleoprotein interactions
Emeline Bouffartigues, Hervé Leh, Marielle Anger-Leroy, Sylvie Rimsky, and Malcolm Buckle
Nucleic Acids Res. 2007 March; 35(6): e39. Published online 2007 February 7. doi: 10.1093/nar/gkm030.
PMCID: PMC1874600
Dual priming oligonucleotide system for the multiplex detection of respiratory viruses and SNP genotyping of CYP2C19 gene
Jong-Yoon Chun, Kyoung-Joong Kim, In-Taek Hwang, Yun-Jee Kim, Dae-Hoon Lee, In-Kyoung Lee, and Jong-Kee Kim
Nucleic Acids Res. 2007 March; 35(6): e40. Published online 2007 February 7. doi: 10.1093/nar/gkm051.
PMCID: PMC1874606
Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation
Tomasz K. Wojdacz and Alexander Dobrovic
Nucleic Acids Res. 2007 March; 35(6): e41. Published online 2007 February 8. doi: 10.1093/nar/gkm013.
PMCID: PMC1874596
Quantitative surface-enhanced resonance Raman scattering of phthalocyanine-labelled oligonucleotides
A. Macaskill, A. A. Chernonosov, V. V. Koval, E. A. Lukyanets, O. S. Fedorova, W. E. Smith, K. Faulds, and D. Graham
Nucleic Acids Res. 2007 March; 35(6): e42. Published online 2007 February 8. doi: 10.1093/nar/gkm042.
PMCID: PMC1874604
Vectors for co-expression of an unrestricted number of proteins
Christoph Scheich, Daniel Kümmel, Dimitri Soumailakakis, Udo Heinemann, and Konrad Büssow
Nucleic Acids Res. 2007 March; 35(6): e43. Published online 2007 February 20. doi: 10.1093/nar/gkm067.
PMCID: PMC1874614
SNP discovery by mismatch-targeting of Mu transposition
Luisa Orsini, Maria Pajunen, Ilkka Hanski, and Harri Savilahti
Nucleic Acids Res. 2007 March; 35(6): e44. Published online 2007 February 20. doi: 10.1093/nar/gkm070.
PMCID: PMC1874615
A versatile ligation-independent cloning method suitable for high-throughput expression screening applications
Nick S. Berrow, David Alderton, Sarah Sainsbury, Joanne Nettleship, Rene Assenberg, Nahid Rahman, David I. Stuart, and Raymond J. Owens
Nucleic Acids Res. 2007 March; 35(6): e45. Published online 2007 February 22. doi: 10.1093/nar/gkm047.
PMCID: PMC1874605
A synthetic luxCDABE gene cluster optimized for expression in high-GC bacteria
Arryn Craney, Tobias Hohenauer, Ye Xu, Naveen Kumar Navani, Yingfu Li, and Justin Nodwell
Nucleic Acids Res. 2007 March; 35(6): e46. Published online 2007 March 1. doi: 10.1093/nar/gkm086.
PMCID: PMC1874620
Computational Biology
Codon conservation in the influenza A virus genome defines RNA packaging signals
Julia R. Gog, Emmanuel Dos Santos Afonso, Rosa M. Dalton, India Leclercq, Laurence Tiley, Debra Elton, Johann C. von Kirchbach, Nadia Naffakh, Nicolas Escriou, and Paul Digard
Nucleic Acids Res. 2007 March; 35(6): 1897–1907. Published online 2007 March 1. doi: 10.1093/nar/gkm087.
PMCID: PMC1874621
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
Stefano Colella, Christopher Yau, Jennifer M. Taylor, Ghazala Mirza, Helen Butler, Penny Clouston, Anne S. Bassett, Anneke Seller, Christopher C. Holmes, and Jiannis Ragoussis
Nucleic Acids Res. 2007 March; 35(6): 2013–2025. Published online 2007 March 6. doi: 10.1093/nar/gkm076.
PMCID: PMC1874617
Nucleic Acid Enzymes
Controlling the motor activity of a transcription-repair coupling factor: autoinhibition and the role of RNA polymerase
Abigail J. Smith, Mark D. Szczelkun, and Nigel J. Savery
Nucleic Acids Res. 2007 March; 35(6): 1802–1811. Published online 2007 February 28. doi: 10.1093/nar/gkm019.
PMCID: PMC1874598
The genomic HDV ribozyme utilizes a previously unnoticed U-turn motif to accomplish fast site-specific catalysis
Jana Sefcikova, Maryna V. Krasovska, Jiří Šponer, and Nils G. Walter
Nucleic Acids Res. 2007 March; 35(6): 1933–1946. Published online 2007 March 2. doi: 10.1093/nar/gkl1104.
PMCID: PMC1874588
USER™ friendly DNA engineering and cloning method by uracil excision
Jurate Bitinaite, Michelle Rubino, Kamini Hingorani Varma, Ira Schildkraut, Romualdas Vaisvila, and Rita Vaiskunaite
Nucleic Acids Res. 2007 March; 35(6): 1992–2002. Published online 2007 March 6. doi: 10.1093/nar/gkm041.
PMCID: PMC1874603
Corrigendum
G-quadruplexes in promoters throughout the human genome
Julian L. Huppert and Shankar Balasubramanian
Nucleic Acids Res. 2007 March; 35(6): 2105. Published online 2007 February 28. doi: 10.1093/nar/gkm109.
PMCID: PMC1874626
Corrects: Julian L. Huppert, et al. G-quadruplexes in promoters throughout the human genome. Nucleic Acids Res. 2007 January; 35(2): 406–413.
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