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Volume 104(12);  March 20, 2007
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4771–4772. doi: 10.1073/iti.1207104.
PMCID: PMC1829210
Commentaries
Unlocking and opening a DNA gate
James C. Wang
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4773–4774. Published online 2007 March 15. doi: 10.1073/pnas.0701070104.
PMCID: PMC1829211
DNA barcoding and the renaissance of taxonomy
Scott E. Miller
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4775–4776. Published online 2007 March 15. doi: 10.1073/pnas.0700466104.
PMCID: PMC1829212
New tools to build synthetic hormonal pathways
Bruce R. Conklin
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4777–4778. Published online 2007 March 12. doi: 10.1073/pnas.0700913104.
PMCID: PMC1829213
Profile
Profile of Monica G. Turner
Nick Zagorski
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4779–4781. Published online 2007 March 12. doi: 10.1073/pnas.0701264104.
PMCID: PMC1829214
Physical Sciences
Applied Mathematics
The role of cells refractory to productive infection in acute hepatitis B viral dynamics
Stanca M. Ciupe, Ruy M. Ribeiro, Patrick W. Nelson, Geoffrey Dusheiko, and Alan S. Perelson
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5050–5055. Published online 2007 March 14. doi: 10.1073/pnas.0603626104.
PMCID: PMC1829262
Applied Physical Sciences
Pattern regulation in the stripe of zebrafish suggests an underlying dynamic and autonomous mechanism
Motoomi Yamaguchi, Eiichi Yoshimoto, and Shigeru Kondo
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4790–4793. Published online 2007 March 12. doi: 10.1073/pnas.0607790104.
PMCID: PMC1820822
Chemistry
Electronic energy delocalization and dissipation in single- and double-stranded DNA
Ivan Buchvarov, Qiang Wang, Milen Raytchev, Anton Trifonov, and Torsten Fiebig
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4794–4797. Published online 2007 March 12. doi: 10.1073/pnas.0606757104.
PMCID: PMC1829217
Functional, fractal nonlinear response with application to rate processes with memory, allometry, and population genetics
Marcel O. Vlad, Federico Morán, Vlad T. Popa, Stefan E. Szedlacsek, and John Ross
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4798–4803. Published online 2007 March 14. doi: 10.1073/pnas.0700397104.
PMCID: PMC1829218
Bound anionic states of adenine
Maciej Harańczyk, Maciej Gutowski, Xiang Li, and Kit H. Bowen
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4804–4807. Published online 2007 March 12. doi: 10.1073/pnas.0609982104.
PMCID: PMC1829219
Synthesis and evaluation of transthyretin amyloidosis inhibitors containing carborane pharmacophores
Richard L. Julius, Omar K. Farha, Janet Chiang, L. Jeanne Perry, and M. Frederick Hawthorne
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4808–4813. Published online 2007 March 13. doi: 10.1073/pnas.0700316104.
PMCID: PMC1829220
Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme
Thomas Durek, Vladimir Yu. Torbeev, and Stephen B. H. Kent
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4846–4851. Published online 2007 March 8. doi: 10.1073/pnas.0610630104.
PMCID: PMC1829227
Environmental Sciences
The importance of the Montreal Protocol in protecting climate
Guus J. M. Velders, Stephen O. Andersen, John S. Daniel, David W. Fahey, and Mack McFarland
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4814–4819. Published online 2007 March 8. doi: 10.1073/pnas.0610328104.
PMCID: PMC1817831
Large seasonal swings in leaf area of Amazon rainforests
Ranga B. Myneni, Wenze Yang, Ramakrishna R. Nemani, Alfredo R. Huete, Robert E. Dickinson, Yuri Knyazikhin, Kamel Didan, Rong Fu, Robinson I. Negrón Juárez, Sasan S. Saatchi, Hirofumi Hashimoto, Kazuhito Ichii, Nikolay V. Shabanov, Bin Tan, Piyachat Ratana, Jeffrey L. Privette, Jeffrey T. Morisette, Eric F. Vermote, David P. Roy, Robert E. Wolfe, Mark A. Friedl, Steven W. Running, Petr Votava, Nazmi El-Saleous, Sadashiva Devadiga, Yin Su, and Vincent V. Salomonson
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4820–4823. Published online 2007 March 13. doi: 10.1073/pnas.0611338104.
PMCID: PMC1820882
Physics
Strong effects of molecular topology on diffusion of entangled DNA molecules
Rae M. Robertson and Douglas E. Smith
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4824–4827. Published online 2007 March 13. doi: 10.1073/pnas.0700137104.
PMCID: PMC1820884
Sustainability Science
Sustainable fuel for the transportation sector
Rakesh Agrawal, Navneet R. Singh, Fabio H. Ribeiro, and W. Nicholas Delgass
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4828–4833. Published online 2007 March 14. doi: 10.1073/pnas.0609921104.
PMCID: PMC1821126
Biological Sciences
Anthropology
Phylogeny and ancient DNA of Sus provides insights into neolithic expansion in Island Southeast Asia and Oceania
Greger Larson, Thomas Cucchi, Masakatsu Fujita, Elizabeth Matisoo-Smith, Judith Robins, Atholl Anderson, Barry Rolett, Matthew Spriggs, Gaynor Dolman, Tae-Hun Kim, Nguyen Thi Dieu Thuy, Ettore Randi, Moira Doherty, Rokus Awe Due, Robert Bollt, Tony Djubiantono, Bion Griffin, Michiko Intoh, Emile Keane, Patrick Kirch, Kuang-Ti Li, Michael Morwood, Lolita M. Pedriña, Philip J. Piper, Ryan J. Rabett, Peter Shooter, Gert Van den Bergh, Eric West, Stephen Wickler, Jing Yuan, Alan Cooper, and Keith Dobney
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4834–4839. Published online 2007 March 14. doi: 10.1073/pnas.0607753104.
PMCID: PMC1829225
Biochemistry
Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase II
R. Derike Smiley, Tammy R. L. Collins, Gordon G. Hammes, and Tao-Shih Hsieh
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4840–4845. Published online 2007 March 14. doi: 10.1073/pnas.0700342104.
PMCID: PMC1829226
Convergent chemical synthesis and high-resolution x-ray structure of human lysozyme
Thomas Durek, Vladimir Yu. Torbeev, and Stephen B. H. Kent
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4846–4851. Published online 2007 March 8. doi: 10.1073/pnas.0610630104.
PMCID: PMC1829227
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor α-binding program on human gene promoters
Young-Soo Kwon, Ivan Garcia-Bassets, Kasey R. Hutt, Christine S. Cheng, Mingjie Jin, Dongyan Liu, Chris Benner, Dong Wang, Zhen Ye, Marina Bibikova, Jian-Bing Fan, Lingxun Duan, Christopher K. Glass, Michael G. Rosenfeld, and Xiang-Dong Fu
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4852–4857. Published online 2007 March 14. doi: 10.1073/pnas.0700715104.
PMCID: PMC1821125
Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand
Christy Rani R. Grace, Marilyn H. Perrin, Jozsef Gulyas, Michael R. DiGruccio, Jeffrey P. Cantle, Jean E. Rivier, Wylie W. Vale, and Roland Riek
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4858–4863. Published online 2007 March 12. doi: 10.1073/pnas.0700682104.
PMCID: PMC1829229
Simultaneous reduction of iron–sulfur protein and cytochrome bL during ubiquinol oxidation in cytochrome bc1 complex
Jian Zhu, Tsuyoshi Egawa, Syun-Ru Yeh, Linda Yu, and Chang-An Yu
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4864–4869. Published online 2007 March 13. doi: 10.1073/pnas.0607812104.
PMCID: PMC1829230
Inhibitory factors associated with anaphase-promoting complex/cylosome in mitotic checkpoint
Ilana Braunstein, Shirly Miniowitz, Yakir Moshe, and Avram Hershko
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4870–4875. Published online 2007 March 13. doi: 10.1073/pnas.0700523104.
PMCID: PMC1829231
S-adenosylmethionine directly inhibits binding of 30S ribosomal subunits to the SMK box translational riboswitch RNA
Ryan T. Fuchs, Frank J. Grundy, and Tina M. Henkin
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4876–4880. Published online 2007 March 9. doi: 10.1073/pnas.0609956104.
PMCID: PMC1829232
Intersubunit movement is required for ribosomal translocation
Lucas H. Horan and Harry F. Noller
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4881–4885. Published online 2007 March 8. doi: 10.1073/pnas.0700762104.
PMCID: PMC1829233
Reduction of 1-Cys peroxiredoxins by ascorbate changes the thiol-specific antioxidant paradigm, revealing another function of vitamin C
Gisele Monteiro, Bruno B. Horta, Daniel Carvalho Pimenta, Ohara Augusto, and Luis E. S. Netto
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4886–4891. Published online 2007 March 14. doi: 10.1073/pnas.0700481104.
PMCID: PMC1829234
Biophysics
Electronic energy delocalization and dissipation in single- and double-stranded DNA
Ivan Buchvarov, Qiang Wang, Milen Raytchev, Anton Trifonov, and Torsten Fiebig
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4794–4797. Published online 2007 March 12. doi: 10.1073/pnas.0606757104.
PMCID: PMC1829217
Strong effects of molecular topology on diffusion of entangled DNA molecules
Rae M. Robertson and Douglas E. Smith
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4824–4827. Published online 2007 March 13. doi: 10.1073/pnas.0700137104.
PMCID: PMC1820884
From the Cover:
Single M13 bacteriophage tethering and stretching
Ahmad S. Khalil, Jorge M. Ferrer, Ricardo R. Brau, Stephen T. Kottmann, Christopher J. Noren, Matthew J. Lang, and Angela M. Belcher
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4892–4897. Published online 2007 March 13. doi: 10.1073/pnas.0605727104.
PMCID: PMC1829235
Accurate, conformation-dependent predictions of solvent effects on protein ionization constants
P. Barth, T. Alber, and P. B. Harbury
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4898–4903. Published online 2007 March 14. doi: 10.1073/pnas.0700188104.
PMCID: PMC1829236
Collective neuronal growth and self organization of axons
P.-G. de Gennes
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4904–4906. Published online 2007 March 12. doi: 10.1073/pnas.0609871104.
PMCID: PMC1829237
Predicting coupling limits from an experimentally determined energy landscape
Timothy O. Street, Christina M. Bradley, and Doug Barrick
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4907–4912. Published online 2007 March 14. doi: 10.1073/pnas.0608756104.
PMCID: PMC1829238
Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method
Andres E. Leschziner, Anjanabha Saha, Jacqueline Wittmeyer, Yongli Zhang, Carlos Bustamante, Bradley R. Cairns, and Eva Nogales
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4913–4918. Published online 2007 March 13. doi: 10.1073/pnas.0700706104.
PMCID: PMC1820885
Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC
Xiaoyong Bao, Sung Chang Lee, Luis Reuss, and Guillermo A. Altenberg
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4919–4924. Published online 2007 March 8. doi: 10.1073/pnas.0603154104.
PMCID: PMC1817834
Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations
Hongxing Lei, Chun Wu, Haiguang Liu, and Yong Duan
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4925–4930. Published online 2007 March 12. doi: 10.1073/pnas.0608432104.
PMCID: PMC1829241
Key feature of the catalytic cycle of TNF-α converting enzyme involves communication between distal protein sites and the enzyme catalytic core
Ariel Solomon, Barak Akabayov, Anatoly Frenkel, Marcos E. Milla, and Irit Sagi
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4931–4936. Published online 2007 March 13. doi: 10.1073/pnas.0700066104.
PMCID: PMC1829242
Cytoskeletal dynamics of human erythrocyte
Ju Li, George Lykotrafitis, Ming Dao, and Subra Suresh
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4937–4942. Published online 2007 March 12. doi: 10.1073/pnas.0700257104.
PMCID: PMC1829243
On the thermodynamic stability of a charged arginine side chain in a transmembrane helix
Sudha Dorairaj and Toby W. Allen
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4943–4948. Published online 2007 March 13. doi: 10.1073/pnas.0610470104.
PMCID: PMC1829244
Cell Biology
A lamin A protein isoform overexpressed in Hutchinson–Gilford progeria syndrome interferes with mitosis in progeria and normal cells
Kan Cao, Brian C. Capell, Michael R. Erdos, Karima Djabali, and Francis S. Collins
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4949–4954. Published online 2007 March 14. doi: 10.1073/pnas.0611640104.
PMCID: PMC1821129
Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging
Thomas Dechat, Takeshi Shimi, Stephen A. Adam, Antonio E. Rusinol, Douglas A. Andres, H. Peter Spielmann, Michael S. Sinensky, and Robert D. Goldman
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4955–4960. Published online 2007 March 14. doi: 10.1073/pnas.0700854104.
PMCID: PMC1829246
Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model
Kris Schauwaers, Karel De Gendt, Philippa T. K. Saunders, Nina Atanassova, Annemie Haelens, Leen Callewaert, Udo Moehren, Johannes V. Swinnen, Guido Verhoeven, Guy Verrijdt, and Frank Claessens
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4961–4966. Published online 2007 March 12. doi: 10.1073/pnas.0610814104.
PMCID: PMC1829247
Ecology
Inorganic nitrogen availability after severe stand-replacing fire in the Greater Yellowstone ecosystem
Monica G. Turner, Erica A. H. Smithwick, Kristine L. Metzger, Daniel B. Tinker, and William H. Romme
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4782–4789. Published online 2007 March 2. doi: 10.1073/pnas.0700180104.
PMCID: PMC1829215
From the Cover:
DNA barcodes affirm that 16 species of apparently generalist tropical parasitoid flies (Diptera, Tachinidae) are not all generalists
M. Alex Smith, D. Monty Wood, Daniel H. Janzen, Winnie Hallwachs, and Paul D. N. Hebert
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4967–4972. Published online 2007 March 14. doi: 10.1073/pnas.0700050104.
PMCID: PMC1821123
From the Cover:
Tradeoffs between income, biodiversity, and ecosystem functioning during tropical rainforest conversion and agroforestry intensification
Ingolf Steffan-Dewenter, Michael Kessler, Jan Barkmann, Merijn M. Bos, Damayanti Buchori, Stefan Erasmi, Heiko Faust, Gerhard Gerold, Klaus Glenk, S. Robbert Gradstein, Edi Guhardja, Marieke Harteveld, Dietrich Hertel, Patrick Höhn, Martin Kappas, Stefan Köhler, Christoph Leuschner, Miet Maertens, Rainer Marggraf, Sonja Migge-Kleian, Johanis Mogea, Ramadhaniel Pitopang, Matthias Schaefer, Stefan Schwarze, Simone G. Sporn, Andrea Steingrebe, Sri S. Tjitrosoedirdjo, Soekisman Tjitrosoemito, André Twele, Robert Weber, Lars Woltmann, Manfred Zeller, and Teja Tscharntke
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4973–4978. Published online 2007 March 14. doi: 10.1073/pnas.0608409104.
PMCID: PMC1829249
Phylogenetic signal in plant pathogen–host range
Gregory S. Gilbert and Campbell O. Webb
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4979–4983. Published online 2007 March 14. doi: 10.1073/pnas.0607968104.
PMCID: PMC1829250
Optimizing the control of disease infestations at the landscape scale
Graeme A. Forster and Christopher A. Gilligan
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4984–4989. Published online 2007 March 13. doi: 10.1073/pnas.0607900104.
PMCID: PMC1829251
Altered soil microbial community at elevated CO2 leads to loss of soil carbon
Karen M. Carney, Bruce A. Hungate, Bert G. Drake, and J. Patrick Megonigal
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4990–4995. Published online 2007 March 13. doi: 10.1073/pnas.0610045104.
PMCID: PMC1820881
Evolution
Rapid evolution of smell and taste receptor genes during host specialization in Drosophila sechellia
Carolyn S. McBride
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4996–5001. Published online 2007 March 9. doi: 10.1073/pnas.0608424104.
PMCID: PMC1829253
Global molecular phylogeography reveals persistent Arctic circumpolar isolation in a marine planktonic protist
Kate F. Darling, Michal Kucera, and Christopher M. Wade
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5002–5007. Published online 2007 March 13. doi: 10.1073/pnas.0700520104.
PMCID: PMC1829254
Innateness and culture in the evolution of language
Simon Kirby, Mike Dowman, and Thomas L. Griffiths
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5241–5245. Published online 2007 March 12. doi: 10.1073/pnas.0608222104.
PMCID: PMC1829293
Genetics
Functional, fractal nonlinear response with application to rate processes with memory, allometry, and population genetics
Marcel O. Vlad, Federico Morán, Vlad T. Popa, Stefan E. Szedlacsek, and John Ross
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4798–4803. Published online 2007 March 14. doi: 10.1073/pnas.0700397104.
PMCID: PMC1829218
An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes
Ben E. Black, Melissa A. Brock, Sabrina Bédard, Virgil L. Woods, Jr., and Don W. Cleveland
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5008–5013. Published online 2007 March 13. doi: 10.1073/pnas.0700390104.
PMCID: PMC1829255
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
Birgit Gerisch, Veerle Rottiers, Dongling Li, Daniel L. Motola, Carolyn L. Cummins, Hans Lehrach, David J. Mangelsdorf, and Adam Antebi
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5014–5019. Published online 2007 March 14. doi: 10.1073/pnas.0700847104.
PMCID: PMC1821127
Evidence of spatially bound gene regulation in Mus musculus: Decreased gene expression proximal to microRNA genomic location
Hidenori Inaoka, Yutaka Fukuoka, and Isaac S. Kohane
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5020–5025. Published online 2007 March 12. doi: 10.1073/pnas.0611078104.
PMCID: PMC1820821
Immunology
Lymphotoxin β receptor signaling is required for inflammatory lymphangiogenesis in the thyroid
Glaucia C. Furtado, Tatjana Marinkovic, Andrea P. Martin, Alexandre Garin, Benjamin Hoch, Wolfgang Hubner, Benjamin K. Chen, Eric Genden, Mihaela Skobe, and Sergio A. Lira
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5026–5031. Published online 2007 March 14. doi: 10.1073/pnas.0606697104.
PMCID: PMC1829258
A model of immune regulation as a consequence of randomized lymphocyte division and death times
E. D. Hawkins, M. L. Turner, M. R. Dowling, C. van Gend, and P. D. Hodgkin
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5032–5037. Published online 2007 March 14. doi: 10.1073/pnas.0700026104.
PMCID: PMC1821128
Stage-dependent reactivity of thymocytes to self-peptide–MHC complexes
Qibin Leng, Qing Ge, Tam Nguyen, Herman N. Eisen, and Jianzhu Chen
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5038–5043. Published online 2007 March 14. doi: 10.1073/pnas.0700674104.
PMCID: PMC1829260
Antiviral and immunoregulatory activities of IFN-γ depend on constitutively expressed IL-1α
Vladimir Hurgin, Daniela Novick, Ariel Werman, Charles A. Dinarello, and Menachem Rubinstein
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5044–5049. Published online 2007 March 8. doi: 10.1073/pnas.0611608104.
PMCID: PMC1817830
Medical Sciences
The role of cells refractory to productive infection in acute hepatitis B viral dynamics
Stanca M. Ciupe, Ruy M. Ribeiro, Patrick W. Nelson, Geoffrey Dusheiko, and Alan S. Perelson
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5050–5055. Published online 2007 March 14. doi: 10.1073/pnas.0603626104.
PMCID: PMC1829262
Osteopenia in X-linked hyper-IgM syndrome reveals a regulatory role for CD40 ligand in osteoclastogenesis
Eduardo Lopez-Granados, Stephane T. Temmerman, Lynne Wu, James C. Reynolds, Dean Follmann, Shuying Liu, David L. Nelson, Frank Rauch, and Ashish Jain
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5056–5061. Published online 2007 March 9. doi: 10.1073/pnas.0605715104.
PMCID: PMC1817828
Role for CD47-SIRPα signaling in xenograft rejection by macrophages
Kentaro Ide, Hui Wang, Hiroyuki Tahara, Jianxiang Liu, Xiaoying Wang, Toshimasa Asahara, Megan Sykes, Yong-Guang Yang, and Hideki Ohdan
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5062–5066. Published online 2007 March 12. doi: 10.1073/pnas.0609661104.
PMCID: PMC1829264
Human herpesvirus 6A accelerates AIDS progression in macaques
Paolo Lusso, Richard W. Crowley, Mauro S. Malnati, Clelia Di Serio, Maurilio Ponzoni, Angelique Biancotto, Phillip D. Markham, and Robert C. Gallo
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5067–5072. Published online 2007 March 14. doi: 10.1073/pnas.0700929104.
PMCID: PMC1829265
Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts
Ingmar Meinecke, Antje Cinski, Anja Baier, Marvin A. Peters, Berno Dankbar, Aline Wille, Andreas Drynda, Heidi Mendoza, Renate E. Gay, Ronald T. Hay, Barbara Ink, Steffen Gay, and Thomas Pap
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5073–5078. Published online 2007 March 14. doi: 10.1073/pnas.0608773104.
PMCID: PMC1829266
A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda
John D. Phillips, Hector A. Bergonia, Christopher A. Reilly, Michael R. Franklin, and James P. Kushner
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5079–5084. Published online 2007 March 9. doi: 10.1073/pnas.0700547104.
PMCID: PMC1820519
From the Cover:
Assisted reproductive technologies do not alter mutation frequency or spectrum
Lee Caperton, Patricia Murphey, Yukiko Yamazaki, C. Alex McMahan, Christi A. Walter, Ryuzo Yanagimachi, and John R. McCarrey
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5085–5090. Published online 2007 March 2. doi: 10.1073/pnas.0611642104.
PMCID: PMC1808421
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow
Linda Yang, Lei Wang, Hartmut Geiger, Jose A. Cancelas, Jun Mo, and Yi Zheng
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5091–5096. Published online 2007 March 12. doi: 10.1073/pnas.0610819104.
PMCID: PMC1829299
Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor
J. Roberto Trujillo, Rick Rogers, Ramon M. Molina, Fernando Dangond, Mary Fran McLane, Max Essex, and Joseph D. Brain
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5097–5102. Published online 2007 March 14. doi: 10.1073/pnas.0611263104.
PMCID: PMC1821124
Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis
Jennifer P. Morton, Michelle E. Mongeau, David S. Klimstra, John P. Morris, Yie Chia Lee, Yoshiya Kawaguchi, Christopher V. E. Wright, Matthias Hebrok, and Brian C. Lewis
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5103–5108. Published online 2007 March 19. doi: 10.1073/pnas.0701158104.
PMCID: PMC1828712
Hypoxia-inducible factor 1α stabilization by carbon monoxide results in cytoprotective preconditioning
Beek Y. Chin, Ge Jiang, Barbara Wegiel, Hong J. Wang, Theresa MacDonald, Xu Chen Zhang, David Gallo, Eva Cszimadia, Fritz H. Bach, Patty J. Lee, and Leo E. Otterbein
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5109–5114. Published online 2007 March 12. doi: 10.1073/pnas.0609611104.
PMCID: PMC1820823
Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
Francesco Dotta, Stefano Censini, Astrid G. S. van Halteren, Lorella Marselli, Matilde Masini, Sabrina Dionisi, Franco Mosca, Ugo Boggi, Andrea Onetti Muda, Stefano Del Prato, John F. Elliott, Antonello Covacci, Rino Rappuoli, Bart O. Roep, and Piero Marchetti
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5115–5120. Published online 2007 March 14. doi: 10.1073/pnas.0700442104.
PMCID: PMC1829272
Microbiology
Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family
Simran Banga, Ping Gao, Xihui Shen, Valena Fiscus, Wei-Xing Zong, Lingling Chen, and Zhao-Qing Luo
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5121–5126. Published online 2007 March 14. doi: 10.1073/pnas.0611030104.
PMCID: PMC1829273
Distinctive features of large complex virus genomes and proteomes
Jan Mrázek and Samuel Karlin
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5127–5132. Published online 2007 March 9. doi: 10.1073/pnas.0700429104.
PMCID: PMC1829274
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
Madhulika Jain, Christopher J. Petzold, Michael W. Schelle, Michael D. Leavell, Joseph D. Mougous, Carolyn R. Bertozzi, Julie A. Leary, and Jeffery S. Cox
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5133–5138. Published online 2007 March 8. doi: 10.1073/pnas.0610634104.
PMCID: PMC1829275
Crystal structures reveal a thiol protease-like catalytic triad in the C-terminal region of Pasteurella multocida toxin
Kengo Kitadokoro, Shigeki Kamitani, Masayuki Miyazawa, Miyuki Hanajima-Ozawa, Aya Fukui, Masami Miyake, and Yasuhiko Horiguchi
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5139–5144. Published online 2007 March 14. doi: 10.1073/pnas.0608197104.
PMCID: PMC1829276
Mycobacterium tuberculosis produces pili during human infection
Christopher J. Alteri, Juan Xicohténcatl-Cortes, Sonja Hess, Guillermo Caballero-Olín, Jorge A. Girón, and Richard L. Friedman
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5145–5150. Published online 2007 March 8. doi: 10.1073/pnas.0602304104.
PMCID: PMC1817835
Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage
Shah M. Faruque, Vincent C. Tam, Nityananda Chowdhury, Pornphan Diraphat, Michelle Dziejman, John F. Heidelberg, John D. Clemens, John J. Mekalanos, and G. Balakrish Nair
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5151–5156. Published online 2007 March 12. doi: 10.1073/pnas.0700365104.
PMCID: PMC1829278
Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
Apoorva Bhatt, Nagatoshi Fujiwara, Kiranmai Bhatt, Sudagar S. Gurcha, Laurent Kremer, Bing Chen, John Chan, Steven A. Porcelli, Kazuo Kobayashi, Gurdyal S. Besra, and William R. Jacobs, Jr.
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5157–5162. Published online 2007 March 12. doi: 10.1073/pnas.0608654104.
PMCID: PMC1829279
Neuroscience
From the Cover:
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand
Blaine N. Armbruster, Xiang Li, Mark H. Pausch, Stefan Herlitze, and Bryan L. Roth
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5163–5168. Published online 2007 March 2. doi: 10.1073/pnas.0700293104.
PMCID: PMC1829280
Differential responses of hippocampal subfields to cortical up–down states
Thomas T. G. Hahn, Bert Sakmann, and Mayank R. Mehta
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5169–5174. Published online 2007 March 12. doi: 10.1073/pnas.0700222104.
PMCID: PMC1829281
First-spike latency information in single neurons increases when referenced to population onset
Steven M. Chase and Eric D. Young
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5175–5180. Published online 2007 March 9. doi: 10.1073/pnas.0610368104.
PMCID: PMC1829282
Prefrontal/accumbal catecholamine system determines motivational salience attribution to both reward- and aversion-related stimuli
Rossella Ventura, Cristina Morrone, and Stefano Puglisi-Allegra
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5181–5186. Published online 2007 March 9. doi: 10.1073/pnas.0610178104.
PMCID: PMC1820518
Dopamine modulation of neuronal Na+ channels requires binding of A kinase-anchoring protein 15and PKA by a modified leucine zipper motif
W. Preston Few, Todd Scheuer, and William A. Catterall
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5187–5192. Published online 2007 March 14. doi: 10.1073/pnas.0611619104.
PMCID: PMC1829284
Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression
Marta Pascual, Ibane Abasolo, Ana Mingorance-Le Meur, Albert Martínez, José A. Del Rio, Christopher V. E. Wright, Francisco X. Real, and Eduardo Soriano
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5193–5198. Published online 2007 March 14. doi: 10.1073/pnas.0605699104.
PMCID: PMC1829285
Peripheral multidendritic sensory neurons are necessary for rhythmic locomotion behavior in Drosophila larvae
Wei Song, Maika Onishi, Lily Yeh Jan, and Yuh Nung Jan
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5199–5204. Published online 2007 March 13. doi: 10.1073/pnas.0700895104.
PMCID: PMC1820883
A genomic screen for activators of the antioxidant response element
Yanxia Liu, Jonathan T. Kern, John R. Walker, Jeffrey A. Johnson, Peter G. Schultz, and Hendrik Luesch
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5205–5210. Published online 2007 March 12. doi: 10.1073/pnas.0700898104.
PMCID: PMC1829287
Neural correlates of perceptual filling-in of an artificial scotoma in humans
R. S. Weil, J. M. Kilner, J. D. Haynes, and G. Rees
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5211–5216. Published online 2007 March 14. doi: 10.1073/pnas.0609294104.
PMCID: PMC1829288
Physiology
Genetic deletion of p66Shc adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress
Giovanni G. Camici, Marzia Schiavoni, Pietro Francia, Markus Bachschmid, Ines Martin-Padura, Martin Hersberger, Felix C. Tanner, PierGiuseppe Pelicci, Massimo Volpe, Piero Anversa, Thomas F. Lüscher, and Francesco Cosentino
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5217–5222. Published online 2007 March 14. doi: 10.1073/pnas.0609656104.
PMCID: PMC1829289
PGC-1β controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis
Junichiro Sonoda, Isaac R. Mehl, Ling-Wa Chong, Russell R. Nofsinger, and Ronald M. Evans
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5223–5228. Published online 2007 March 12. doi: 10.1073/pnas.0611623104.
PMCID: PMC1829290
Absence of the proapoptotic Bax protein extends fertility and alleviates age-related health complications in female mice
Gloria I. Perez, Andrea Jurisicova, Lisa Wise, Tatiana Lipina, Marijana Kanisek, Allison Bechard, Yasushi Takai, Patricia Hunt, John Roder, Marc Grynpas, and Jonathan L. Tilly
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5229–5234. Published online 2007 March 8. doi: 10.1073/pnas.0608557104.
PMCID: PMC1817832
Ca2+ sparks operated by membrane depolarization require isoform 3 ryanodine receptor channels in skeletal muscle
Sandrine Pouvreau, Leandro Royer, Jianxun Yi, Gustavo Brum, Gerhard Meissner, Eduardo Ríos, and Jingsong Zhou
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5235–5240. Published online 2007 March 14. doi: 10.1073/pnas.0700748104.
PMCID: PMC1829292
Social Sciences
Anthropology
Phylogeny and ancient DNA of Sus provides insights into neolithic expansion in Island Southeast Asia and Oceania
Greger Larson, Thomas Cucchi, Masakatsu Fujita, Elizabeth Matisoo-Smith, Judith Robins, Atholl Anderson, Barry Rolett, Matthew Spriggs, Gaynor Dolman, Tae-Hun Kim, Nguyen Thi Dieu Thuy, Ettore Randi, Moira Doherty, Rokus Awe Due, Robert Bollt, Tony Djubiantono, Bion Griffin, Michiko Intoh, Emile Keane, Patrick Kirch, Kuang-Ti Li, Michael Morwood, Lolita M. Pedriña, Philip J. Piper, Ryan J. Rabett, Peter Shooter, Gert Van den Bergh, Eric West, Stephen Wickler, Jing Yuan, Alan Cooper, and Keith Dobney
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4834–4839. Published online 2007 March 14. doi: 10.1073/pnas.0607753104.
PMCID: PMC1829225
Psychology
Innateness and culture in the evolution of language
Simon Kirby, Mike Dowman, and Thomas L. Griffiths
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5241–5245. Published online 2007 March 12. doi: 10.1073/pnas.0608222104.
PMCID: PMC1829293
Compatibility of basic social perceptions determines perceived attractiveness
Kerri L. Johnson and Louis G. Tassinary
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5246–5251. Published online 2007 March 13. doi: 10.1073/pnas.0608181104.
PMCID: PMC1829294
Sustainability Science
From the Cover:
Tradeoffs between income, biodiversity, and ecosystem functioning during tropical rainforest conversion and agroforestry intensification
Ingolf Steffan-Dewenter, Michael Kessler, Jan Barkmann, Merijn M. Bos, Damayanti Buchori, Stefan Erasmi, Heiko Faust, Gerhard Gerold, Klaus Glenk, S. Robbert Gradstein, Edi Guhardja, Marieke Harteveld, Dietrich Hertel, Patrick Höhn, Martin Kappas, Stefan Köhler, Christoph Leuschner, Miet Maertens, Rainer Marggraf, Sonja Migge-Kleian, Johanis Mogea, Ramadhaniel Pitopang, Matthias Schaefer, Stefan Schwarze, Simone G. Sporn, Andrea Steingrebe, Sri S. Tjitrosoedirdjo, Soekisman Tjitrosoemito, André Twele, Robert Weber, Lars Woltmann, Manfred Zeller, and Teja Tscharntke
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 4973–4978. Published online 2007 March 14. doi: 10.1073/pnas.0608409104.
PMCID: PMC1829249
Correction
Correction for Hebbeln et al., Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module
Proc Natl Acad Sci U S A. 2007 March 20; 104(12): 5252. Published online 2007 March 9. doi: 10.1073/pnas.0701704104.
PMCID: PMC1829295
Corrects: Peter Hebbeln, et al. Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module. Proc Natl Acad Sci U S A. 2007 February 20; 104(8): 2909–2914.
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