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Volume 104(5);  January 30, 2007
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1443–1444. doi: 10.1073/iti0507104.
PMCID: PMC1785265
Commentaries
Transmembrane transporters: An open and closed case
Robert M. Stroud
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1445–1446. Published online 2007 January 24. doi: 10.1073/pnas.0610349104.
PMCID: PMC1785277
Chemical trails and the parasites that follow them
Dickson D. Despommier
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1447–1448. Published online 2007 January 23. doi: 10.1073/pnas.0610778104.
PMCID: PMC1785285
A new human retrovirus associated with prostate cancer
Hung Fan
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1449–1450. Published online 2007 January 23. doi: 10.1073/pnas.0610912104.
PMCID: PMC1785241
Physical Sciences
Applied Physical Sciences
From the Cover:
Semiotic dynamics and collaborative tagging
Ciro Cattuto, Vittorio Loreto, and Luciano Pietronero
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1461–1464. Published online 2007 January 23. doi: 10.1073/pnas.0610487104.
PMCID: PMC1785269
Chemistry
Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state
Dmitriy Lukoyanov, Brett M. Barney, Dennis R. Dean, Lance C. Seefeldt, and Brian M. Hoffman
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1451–1455. Published online 2007 January 24. doi: 10.1073/pnas.0610975104.
PMCID: PMC1785236
Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV
Ivaylo Ivanov, John A. Tainer, and J. Andrew McCammon
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1465–1470. Published online 2007 January 22. doi: 10.1073/pnas.0603468104.
PMCID: PMC1780068
Chiral imine copper chloride-catalyzed enantioselective desymmetrization of 2-substituted 1,2,3-propanetriols
Byunghyuck Jung and Sung Ho Kang
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1471–1475. Published online 2007 January 22. doi: 10.1073/pnas.0607865104.
PMCID: PMC1785247
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis
Rebecca A. Butcher, Frank C. Schroeder, Michael A. Fischbach, Paul D. Straight, Roberto Kolter, Christopher T. Walsh, and Jon Clardy
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1506–1509. Published online 2007 January 18. doi: 10.1073/pnas.0610503104.
PMCID: PMC1785240
Ligand configurational entropy and protein binding
Chia-en A. Chang, Wei Chen, and Michael K. Gilson
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1534–1539. Published online 2007 January 22. doi: 10.1073/pnas.0610494104.
PMCID: PMC1780070
Physics
Superfluid transition of homogeneous and trapped two-dimensional Bose gases
Markus Holzmann, Gordon Baym, Jean-Paul Blaizot, and Franck Laloë
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1476–1481. Published online 2007 January 23. doi: 10.1073/pnas.0609957104.
PMCID: PMC1785267
Biological Sciences
Applied Biological Sciences
Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus
Samuel K. Lai, D. Elizabeth O'Hanlon, Suzanne Harrold, Stan T. Man, Ying-Ying Wang, Richard Cone, and Justin Hanes
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1482–1487. Published online 2007 January 23. doi: 10.1073/pnas.0608611104.
PMCID: PMC1785284
Large-scale phosphorylation analysis of mouse liver
Judit Villén, Sean A. Beausoleil, Scott A. Gerber, and Steven P. Gygi
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1488–1493. Published online 2007 January 22. doi: 10.1073/pnas.0609836104.
PMCID: PMC1785252
Biochemistry
Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state
Dmitriy Lukoyanov, Brett M. Barney, Dennis R. Dean, Lance C. Seefeldt, and Brian M. Hoffman
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1451–1455. Published online 2007 January 24. doi: 10.1073/pnas.0610975104.
PMCID: PMC1785236
Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine
Roberta Leonardi, Charles O. Rock, Suzanne Jackowski, and Yong-Mei Zhang
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1494–1499. Published online 2007 January 22. doi: 10.1073/pnas.0607621104.
PMCID: PMC1785270
From the Cover:
Topological locking restrains replication fork reversal
Marta Fierro-Fernández, Pablo Hernández, Dora B. Krimer, Andrzej Stasiak, and Jorge B. Schvartzman
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1500–1505. Published online 2007 January 22. doi: 10.1073/pnas.0609204104.
PMCID: PMC1780069
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis
Rebecca A. Butcher, Frank C. Schroeder, Michael A. Fischbach, Paul D. Straight, Roberto Kolter, Christopher T. Walsh, and Jon Clardy
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1506–1509. Published online 2007 January 18. doi: 10.1073/pnas.0610503104.
PMCID: PMC1785240
β-Sheet core of human prion protein amyloid fibrils as determined by hydrogen/deuterium exchange
Xiaojun Lu, Patrick L. Wintrode, and Witold K. Surewicz
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1510–1515. Published online 2007 January 22. doi: 10.1073/pnas.0608447104.
PMCID: PMC1785245
A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness
R. Ficarella, F. Di Leva, M. Bortolozzi, S. Ortolano, F. Donaudy, M. Petrillo, S. Melchionda, A. Lelli, T. Domi, L. Fedrizzi, D. Lim, G. E. Shull, P. Gasparini, M. Brini, F. Mammano, and E. Carafoli
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1516–1521. Published online 2007 January 18. doi: 10.1073/pnas.0609775104.
PMCID: PMC1785272
High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing
Kara Juneau, Curtis Palm, Molly Miranda, and Ronald W. Davis
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1522–1527. Published online 2007 January 23. doi: 10.1073/pnas.0610354104.
PMCID: PMC1780280
Biophysics
Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations
Kusai A. Merchant, Robert B. Best, John M. Louis, Irina V. Gopich, and William A. Eaton
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1528–1533. Published online 2007 January 24. doi: 10.1073/pnas.0607097104.
PMCID: PMC1785253
Ligand configurational entropy and protein binding
Chia-en A. Chang, Wei Chen, and Michael K. Gilson
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1534–1539. Published online 2007 January 22. doi: 10.1073/pnas.0610494104.
PMCID: PMC1780070
Liposome reconstitution and modulation of recombinant N-methyl-d-aspartate receptor channels by membrane stretch
Anna Kloda, Linda Lua, Rhonda Hall, David J. Adams, and Boris Martinac
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1540–1545. Published online 2007 January 22. doi: 10.1073/pnas.0609649104.
PMCID: PMC1780071
Distortion product otoacoustic emissions measured as vibration on the eardrum of human subjects
E. Dalhoff, D. Turcanu, H.-P. Zenner, and A. W. Gummer
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1546–1551. Published online 2007 January 22. doi: 10.1073/pnas.0610185103.
PMCID: PMC1780065
Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry
Janna G. Kiselar, Rachel Mahaffy, Thomas D. Pollard, Steven C. Almo, and Mark R. Chance
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1552–1557. Published online 2007 January 24. doi: 10.1073/pnas.0605380104.
PMCID: PMC1785275
Cell Biology
The specialized cytosolic J-protein, Jjj1, functions in 60S ribosomal subunit biogenesis
Alison E. Meyer, Nai-Jung Hung, Peizhen Yang, Arlen W. Johnson, and Elizabeth A. Craig
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1558–1563. Published online 2007 January 22. doi: 10.1073/pnas.0610704104.
PMCID: PMC1785244
AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells
Diego Gravotta, Ami Deora, Emilie Perret, Claudia Oyanadel, Andrea Soza, Ryan Schreiner, Alfonso Gonzalez, and Enrique Rodriguez-Boulan
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1564–1569. Published online 2007 January 23. doi: 10.1073/pnas.0610700104.
PMCID: PMC1785260
Developmental Biology
Liver growth in the embryo and during liver regeneration in zebrafish requires the cell cycle regulator, uhrf1
Kirsten C. Sadler, Katherine N. Krahn, Naseem A. Gaur, and Chinweike Ukomadu
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1570–1575. Published online 2007 January 22. doi: 10.1073/pnas.0610774104.
PMCID: PMC1785278
Evolution
Biplane wing planform and flight performance of the feathered dinosaur Microraptor gui
Sankar Chatterjee and R. Jack Templin
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1576–1580. Published online 2007 January 22. doi: 10.1073/pnas.0609975104.
PMCID: PMC1780066
Context modulates signal meaning in primate communication
Jessica C. Flack and Frans de Waal
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1581–1586. Published online 2007 January 23. doi: 10.1073/pnas.0603565104.
PMCID: PMC1780279
Chromosome-wide linkage disequilibrium as a consequence of meiotic drive
Kelly A. Dyer, Brian Charlesworth, and John Jaenike
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1587–1592. Published online 2007 January 22. doi: 10.1073/pnas.0605578104.
PMCID: PMC1785283
Genetics
Interaction of the Wiskott–Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells
Karen Badour, Mary K. H. McGavin, Jinyi Zhang, Spencer Freeman, Claudia Vieira, Dominik Filipp, Michael Julius, Gordon B. Mills, and Katherine A. Siminovitch
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1593–1598. Published online 2007 January 22. doi: 10.1073/pnas.0610543104.
PMCID: PMC1785243
Immunology
Estimation of the rate of killing by cytotoxic T lymphocytes in vivo
Roland R. Regoes, Daniel L. Barber, Rafi Ahmed, and Rustom Antia
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1599–1603. Published online 2007 January 22. doi: 10.1073/pnas.0508830104.
PMCID: PMC1785271
MicroRNA-155 is induced during the macrophage inflammatory response
Ryan M. O'Connell, Konstantin D. Taganov, Mark P. Boldin, Genhong Cheng, and David Baltimore
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1604–1609. Published online 2007 January 22. doi: 10.1073/pnas.0610731104.
PMCID: PMC1780072
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
Masayuki Tsuji, Reiko Shinkura, Kazuki Kuroda, Daisuke Yabe, and Tasuku Honjo
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1610–1615. Published online 2007 January 22. doi: 10.1073/pnas.0610520104.
PMCID: PMC1785279
Medical Sciences
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
Ai Kotani, Naoki Kakazu, Tatsuaki Tsuruyama, Il-mi Okazaki, Masamichi Muramatsu, Kazuo Kinoshita, Hitoshi Nagaoka, Daisuke Yabe, and Tasuku Honjo
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1616–1620. Published online 2007 January 24. doi: 10.1073/pnas.0610732104.
PMCID: PMC1785248
Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury
Li Zhu, Wolfgang Bergmeier, Jie Wu, Hong Jiang, Timothy J. Stalker, Marcin Cieslak, Ran Fan, Laurence Boumsell, Atsushi Kumanogoh, Hitoshi Kikutani, Luca Tamagnone, Denisa D. Wagner, Marcos E. Milla, and Lawrence F. Brass
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1621–1626. Published online 2007 January 23. doi: 10.1073/pnas.0606344104.
PMCID: PMC1785259
From the Cover:
Urocanic acid is a major chemoattractant for the skin-penetrating parasitic nematode Strongyloides stercoralis
Daniel Safer, Mario Brenes, Seth Dunipace, and Gerhard Schad
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1627–1630. Published online 2007 January 18. doi: 10.1073/pnas.0610193104.
PMCID: PMC1785286
Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1
Zakir Hossain, Safiah Mohamed Ali, Hui Ling Ko, Jianliang Xu, Chee Peng Ng, Ke Guo, Zeng Qi, Sathivel Ponniah, Wanjin Hong, and Walter Hunziker
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1631–1636. Published online 2007 January 24. doi: 10.1073/pnas.0605266104.
PMCID: PMC1785239
Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet β cell microchimerism
J. Lee Nelson, Kathleen M. Gillespie, Nathalie C. Lambert, Anne M. Stevens, Laurence S. Loubiere, Joe C. Rutledge, Wendy M. Leisenring, Timothy D. Erickson, Zhen Yan, Meghan E. Mullarkey, Nick D. Boespflug, Polly J. Bingley, and Edwin A. M. Gale
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1637–1642. Published online 2007 January 23. doi: 10.1073/pnas.0606169104.
PMCID: PMC1785262
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair
Maria Mirotsou, Zhongyan Zhang, Arjun Deb, Lunan Zhang, Massimiliano Gnecchi, Nicolas Noiseux, Hui Mu, Alok Pachori, and Victor Dzau
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1643–1648. Published online 2007 January 24. doi: 10.1073/pnas.0610024104.
PMCID: PMC1785280
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene
Laëtitia Michou, Sandra Lasbleiz, Anne-Christine Rat, Paola Migliorini, Alejandro Balsa, René Westhovens, Pilar Barrera, Helena Alves, Céline Pierlot, Elodie Glikmans, Sophie Garnier, Jean Dausset, Carlos Vaz, Manuela Fernandes, Elisabeth Petit-Teixeira, Isabelle Lemaire, Dora Pascual-Salcedo, Stefano Bombardieri, Jan Dequeker, Timothy R. Radstake, Piet Van Riel, Leo van de Putte, Antonio Lopes-Vaz, Bernard Prum, Thomas Bardin, Philippe Dieudé, François Cornélis, and European Consortium on Rheumatoid Arthritis Families
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1649–1654. Published online 2007 January 19. doi: 10.1073/pnas.0610250104.
PMCID: PMC1785249
Microbiology
Synthesis of Clostridium cellulovorans minicellulosomes by intercellular complementation
Takamitsu Arai, Satoshi Matsuoka, Hee-Yeon Cho, Hideaki Yukawa, Masayuki Inui, Sui-Lam Wong, and Roy H. Doi
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1456–1460. Published online 2007 January 23. doi: 10.1073/pnas.0610740104.
PMCID: PMC1785254
From the Cover:
An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors
Beihua Dong, Sanggu Kim, Seunghee Hong, Jaydip Das Gupta, Krishnamurthy Malathi, Eric A. Klein, Don Ganem, Joseph L. DeRisi, Samson A. Chow, and Robert H. Silverman
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1655–1660. Published online 2007 January 18. doi: 10.1073/pnas.0610291104.
PMCID: PMC1776164
Critical role of PA28γ in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis
Kohji Moriishi, Rika Mochizuki, Kyoji Moriya, Hironobu Miyamoto, Yoshio Mori, Takayuki Abe, Shigeo Murata, Keiji Tanaka, Tatsuo Miyamura, Tetsuro Suzuki, Kazuhiko Koike, and Yoshiharu Matsuura
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1661–1666. Published online 2007 January 18. doi: 10.1073/pnas.0607312104.
PMCID: PMC1776165
RNaseE and the other constituents of the RNA degradosome are components of the bacterial cytoskeleton
Aziz Taghbalout and Lawrence Rothfield
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1667–1672. Published online 2007 January 22. doi: 10.1073/pnas.0610491104.
PMCID: PMC1785250
NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system
Richard Bayliss, Richard Harris, Loic Coutte, Amy Monier, Remi Fronzes, Peter J. Christie, Paul C. Driscoll, and Gabriel Waksman
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1673–1678. Published online 2007 January 23. doi: 10.1073/pnas.0609535104.
PMCID: PMC1785264
Neuroscience
From the Cover:
Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL
Edwin C. T. Oh, Naheed Khan, Elena Novelli, Hemant Khanna, Enrica Strettoi, and Anand Swaroop
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1679–1684. Published online 2007 January 22. doi: 10.1073/pnas.0605934104.
PMCID: PMC1780067
Corticothalamic feedback enhances stimulus response precision in the visual system
Ian M. Andolina, Helen E. Jones, Wei Wang, and Adam M. Sillito
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1685–1690. Published online 2007 January 19. doi: 10.1073/pnas.0609318104.
PMCID: PMC1785251
Stimulation of endogenous neurogenesis by anti-EFRH immunization in a transgenic mouse model of Alzheimer's disease
Maria Becker, Vered Lavie, and Beka Solomon
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1691–1696. Published online 2007 January 22. doi: 10.1073/pnas.0610180104.
PMCID: PMC1785268
Imaging synaptosomal calcium concentration microdomains and vesicle fusion by using total internal reflection fluorescent microscopy
Yafell Serulle, Mutsuyuki Sugimori, and Rodolfo R. Llinás
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1697–1702. Published online 2007 January 22. doi: 10.1073/pnas.0610741104.
PMCID: PMC1785242
Octopamine modulates honey bee dance behavior
Andrew B. Barron, Ryszard Maleszka, Robert K. Vander Meer, and Gene E. Robinson
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1703–1707. Published online 2007 January 19. doi: 10.1073/pnas.0610506104.
PMCID: PMC1779631
Plant Biology
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait loci
Joost J. B. Keurentjes, Jingyuan Fu, Inez R. Terpstra, Juan M. Garcia, Guido van den Ackerveken, L. Basten Snoek, Anton J. M. Peeters, Dick Vreugdenhil, Maarten Koornneef, and Ritsert C. Jansen
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1708–1713. Published online 2007 January 19. doi: 10.1073/pnas.0610429104.
PMCID: PMC1785256
RNAi-associated ssRNA-specific ribonucleases in Tombusvirus P19 mutant-infected plants and evidence for a discrete siRNA-containing effector complex
Rustem T. Omarov, Jessica J. Ciomperlik, and Herman B. Scholthof
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1714–1719. Published online 2007 January 23. doi: 10.1073/pnas.0608117104.
PMCID: PMC1785274
A Medicago truncatula phosphate transporter indispensable for the arbuscular mycorrhizal symbiosis
Hélène Javot, R. Varma Penmetsa, Nadia Terzaghi, Douglas R. Cook, and Maria J. Harrison
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1720–1725. Published online 2007 January 22. doi: 10.1073/pnas.0608136104.
PMCID: PMC1785290
Psychology
Patients with hippocampal amnesia cannot imagine new experiences
Demis Hassabis, Dharshan Kumaran, Seralynne D. Vann, and Eleanor A. Maguire
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1726–1731. Published online 2007 January 17. doi: 10.1073/pnas.0610561104.
PMCID: PMC1773058
Corrections
Correction for Wagoner and Baker, Assessing implicit models for nonpolar mean solvation forces: The importance of dispersion and volume terms
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1732. Published online 2007 January 18. doi: 10.1073/pnas.0610582103.
PMCID: PMC1785276
Corrects: Jason A. Wagoner, et al. Assessing implicit models for nonpolar mean solvation forces: The importance of dispersion and volume terms. Proc Natl Acad Sci U S A. 2006 May 30; 103(22): 8331–8336.
Correction for Scheuber et al., Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses
Proc Natl Acad Sci U S A. 2007 January 30; 104(5): 1732–1733. Published online 2007 January 18. doi: 10.1073/pnas.0611561104.
PMCID: PMC1785281
Corrects: Anita Scheuber, et al. Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapses. Proc Natl Acad Sci U S A. 2006 October 31; 103(44): 16562–16567.
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