| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 687–688. doi: 10.1073/iti0307104.PMCID: PMC1783372 Commentaries Nonpeptidic glucagon-like peptide 1 receptor agonists: A magic bullet for diabetes? K. G. Murphy and S. R. Bloom PMCID: PMC1783373 Deception point: Peptidoglycan modification as a means of immune evasion Jennifer L. Bishop, Erin C. Boyle, and B. Brett Finlay PMCID: PMC1783374 Profile Profile of J. Woodland Hastings Tinsley H. Davis PMCID: PMC1783375 Physical Sciences Applied Mathematics Noise can play an organizing role for the recurrent dynamics in excitable media Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E PMCID: PMC1783377 Improved evolutionary optimization from genetically adaptive multimethod search Jasper A. Vrugt and Bruce A. Robinson PMCID: PMC1766340 Chemistry DNA folding and melting observed in real time redefine the energy landscape Hairong Ma, Chaozhi Wan, Aiguo Wu, and Ahmed H. Zewail PMCID: PMC1766338 A precise packing sequence for self-assembled convex structures Ting Chen, Zhenli Zhang, and Sharon C. Glotzer PMCID: PMC1783380 Photoselected electron transfer pathways in DNA photolyase Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis PMCID: PMC1783394 Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner PMCID: PMC1783395 Computer Sciences A consensus view of protein dynamics Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco PMCID: PMC1783393 Mathematics On positivity of certain systems of partial differential equations Alberto Parmeggiani PMCID: PMC1783381 Physics Characterization and application of single fluorescent nanodiamonds as cellular biomarkers Chi-Cheng Fu, Hsu-Yang Lee, Kowa Chen, Tsong-Shin Lim, Hsiao-Yun Wu, Po-Keng Lin, Pei-Kuen Wei, Pei-Hsi Tsao, Huan-Cheng Chang, and Wunshain Fann PMCID: PMC1783382 Effects of lengthscales and attractions on the collapse of hydrophobic polymers in water Manoj V. Athawale, Gaurav Goel, Tuhin Ghosh, Thomas M. Truskett, and Shekhar Garde PMCID: PMC1766333 Biological Sciences Anthropology Freshly excavated fossil bones are best for amplification of ancient DNA Mélanie Pruvost, Reinhard Schwarz, Virginia Bessa Correia, Sophie Champlot, Séverine Braguier, Nicolas Morel, Yolanda Fernandez-Jalvo, Thierry Grange, and Eva-Maria Geigl PMCID: PMC1783384 Biochemistry The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis M. Joanne Lemieux, Sarah J. Fischer, Maia M. Cherney, Katherine S. Bateman, and Michael N. G. James PMCID: PMC1783385 Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB Lauren E. Frick, James C. Delaney, Cintyu Wong, Catherine L. Drennan, and John M. Essigmann PMCID: PMC1783386 Biophysics Noise can play an organizing role for the recurrent dynamics in excitable media Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E PMCID: PMC1783377 Flat and sigmoidally curved contact zones in vesicle–vesicle adhesion P. Ziherl and S. Svetina PMCID: PMC1766337 From the Cover:
Neutron scattering reveals extremely slow cell water in a Dead Sea organism Moeava Tehei, Bruno Franzetti, Kathleen Wood, Frank Gabel, Elisa Fabiani, Marion Jasnin, Michaela Zamponi, Dieter Oesterhelt, Giuseppe Zaccai, Margaret Ginzburg, and Ben-Zion Ginzburg PMCID: PMC1783388 The power stroke of myosin VI and the basis of reverse directionality Zev Bryant, David Altman, and James A. Spudich PMCID: PMC1713167 The unique insert at the end of the myosin VI motor is the sole determinant of directionality Hyokeun Park, Anna Li, Li-Qiong Chen, Anne Houdusse, Paul R. Selvin, and H. Lee Sweeney PMCID: PMC1764864 Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain Kae-Jung Hwang, Fatemeh Mahmoodian, James A. Ferretti, Edward D. Korn, and James M. Gruschus PMCID: PMC1783391 Structure of the light-harvesting bacteriochlorophyll c assembly in chlorosomes from Chlorobium limicola determined by solid-state NMR Ayako Egawa, Toshimichi Fujiwara, Tadashi Mizoguchi, Yoshinori Kakitani, Yasushi Koyama, and Hideo Akutsu PMCID: PMC1783392 A consensus view of protein dynamics Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco PMCID: PMC1783393 Photoselected electron transfer pathways in DNA photolyase Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis PMCID: PMC1783394 Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner PMCID: PMC1783395 A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, and Sylvie Doublié PMCID: PMC1783396 Cell Biology Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase Bin Zheng and Lewis C. Cantley PMCID: PMC1783397 Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype Nienwen Chow, Robert D. Bell, Rashid Deane, Jeffrey W. Streb, Jiyuan Chen, Andrew Brooks, William Van Nostrand, Joseph M. Miano, and Berislav V. Zlokovic PMCID: PMC1783398 Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex Qinghong Zhang, Su-Yan Wang, Capucine Fleuriel, Dominique Leprince, Jonathan V. Rocheleau, David W. Piston, and Richard H. Goodman PMCID: PMC1783399 Developmental Biology Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126) Caroline Schmitz, Parag Kinge, and Harald Hutter PMCID: PMC1783400 The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity John E. Pimanda, Ian J. Donaldson, Marella F. T. R. de Bruijn, Sarah Kinston, Kathy Knezevic, Liz Huckle, Sandie Piltz, Josette-Renée Landry, Anthony R. Green, David Tannahill, and Berthold Göttgens PMCID: PMC1783401 Baf60c is a nuclear Notch signaling component required for the establishment of left–right asymmetry Jun K. Takeuchi, Heiko Lickert, Brent W. Bisgrove, Xin Sun, Masamichi Yamamoto, Kallayanee Chawengsaksophak, Hiroshi Hamada, H. Joseph Yost, Janet Rossant, and Benoit G. Bruneau PMCID: PMC1783402 Polycomb-like genes are necessary for specification of dopaminergic and serotonergic neurons in Caenorhabditis elegans Yong Yang, Yinyan Sun, Xin Luo, Yuxia Zhang, Yaoyao Chen, E. Tian, Robyn Lints, and Hong Zhang PMCID: PMC1783403 Ecology Smelling home can prevent dispersal of reef fish larvae Gabriele Gerlach, Jelle Atema, Michael J. Kingsford, Kerry P. Black, and Vanessa Miller-Sims PMCID: PMC1783404 Soil nutrients influence spatial distributions of tropical tree species Robert John, James W. Dalling, Kyle E. Harms, Joseph B. Yavitt, Robert F. Stallard, Matthew Mirabello, Stephen P. Hubbell, Renato Valencia, Hugo Navarrete, Martha Vallejo, and Robin B. Foster PMCID: PMC1783405 Evolution INAUGURAL ARTICLE by a Recently Elected Academy Member: Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species Liyun Liu and J. Woodland Hastings PMCID: PMC1783376 Improved evolutionary optimization from genetically adaptive multimethod search Jasper A. Vrugt and Bruce A. Robinson PMCID: PMC1766340 Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution Tal Dagan and William Martin PMCID: PMC1783406 From the Cover:
Cooperation and conflict in microbial biofilms Joao B. Xavier and Kevin R. Foster PMCID: PMC1783407 Modern origin of numerous alternatively spliced human introns from tandem arrays Degen Zhuo, Richard Madden, Sherif Abou Elela, and Benoit Chabot PMCID: PMC1783408 Global patterns of diversification in the history of modern amphibians Kim Roelants, David J. Gower, Mark Wilkinson, Simon P. Loader, S. D. Biju, Karen Guillaume, Linde Moriau, and Franky Bossuyt PMCID: PMC1783409 Genetics Role of SUMO in the dynamics of telomere maintenance in fission yeast Blerta Xhemalce, Eva Madi Riising, Peter Baumann, Anne Dejean, Benoît Arcangioli, and Jacob-S. Seeler PMCID: PMC1783410 Epigenetic memory at malaria virulence genes Thanat Chookajorn, Ron Dzikowski, Matthias Frank, Felomena Li, Alisha Z. Jiwani, Daniel L. Hartl, and Kirk W. Deitsch PMCID: PMC1764221 Immunology Role for rearranged variable gene segments in directing secondary T cell receptor α recombination Abbas Hawwari and Michael S. Krangel PMCID: PMC1783412 Negative feedback loop in T cell activation through IκB kinase-induced phosphorylation and degradation of Bcl10 Camille Lobry, Tatiana Lopez, Alain Israël, and Robert Weil PMCID: PMC1783413 Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFκB Hai-Chon Lee and Steven F. Ziegler PMCID: PMC1783414 Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis Francesca Odoardi, Naoto Kawakami, Zhaoxia Li, Chiara Cordiglieri, Kristina Streyl, Mikhail Nosov, Wolfgang E. F. Klinkert, Joachim W. Ellwart, Jan Bauer, Hans Lassmann, Hartmut Wekerle, and Alexander Flügel PMCID: PMC1783415 WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP) Miguel A. de la Fuente, Yoji Sasahara, Marco Calamito, Inés M. Antón, Abdallah Elkhal, Maria D. Gallego, Koduru Suresh, Katherine Siminovitch, Hans D. Ochs, Kenneth C. Anderson, Fred S. Rosen, Raif S. Geha, and Narayanaswamy Ramesh PMCID: PMC1783416 Medical Sciences Biomimetic amplification of nanoparticle homing to tumors Dmitri Simberg, Tasmia Duza, Ji Ho Park, Markus Essler, Jan Pilch, Lianglin Zhang, Austin M. Derfus, Meng Yang, Robert M. Hoffman, Sangeeta Bhatia, Michael J. Sailor, and Erkki Ruoslahti PMCID: PMC1783417 From the Cover:
Small-molecule agonists for the glucagon-like peptide 1 receptor Lotte Bjerre Knudsen, Dan Kiel, Min Teng, Carsten Behrens, Dilip Bhumralkar, János T. Kodra, Jens J. Holst, Claus B. Jeppesen, Michael D. Johnson, Johannes Cornelis de Jong, Anker Steen Jorgensen, Tim Kercher, Jarek Kostrowicki, Peter Madsen, Preben H. Olesen, Jacob S. Petersen, Fritz Poulsen, Ulla G. Sidelmann, Jeppe Sturis, Larry Truesdale, John May, and Jesper Lau PMCID: PMC1783418 From the Cover:
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice Desu Chen, Jiayu Liao, Na Li, Caihong Zhou, Qing Liu, Guangxing Wang, Rui Zhang, Song Zhang, Lilin Lin, Kaixian Chen, Xin Xie, Fajun Nan, Andrew A. Young, and Ming-Wei Wang PMCID: PMC1764862 Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1 Sophie Bensing, Sergueï O. Fetissov, Jan Mulder, Jaakko Perheentupa, Jan Gustafsson, Eystein S. Husebye, Mikael Oscarson, Olov Ekwall, Patricia A. Crock, Tomas Hökfelt, Anna-Lena Hulting, and Olle Kämpe PMCID: PMC1783420 Molecular markers of early Parkinson's disease based on gene expression in blood Clemens R. Scherzer, Aron C. Eklund, Lee J. Morse, Zhixiang Liao, Joseph J. Locascio, Daniel Fefer, Michael A. Schwarzschild, Michael G. Schlossmacher, Michael A. Hauser, Jeffery M. Vance, Lewis R. Sudarsky, David G. Standaert, John H. Growdon, Roderick V. Jensen, and Steven R. Gullans PMCID: PMC1766335 Detecting and assessing macrophages in vivo to evaluate atherosclerosis noninvasively using molecular MRI Vardan Amirbekian, Michael J. Lipinski, Karen C. Briley-Saebo, Smbat Amirbekian, Juan Gilberto S. Aguinaldo, David B. Weinreb, Esad Vucic, Juan C. Frias, Fabien Hyafil, Venkatesh Mani, Edward A. Fisher, and Zahi A. Fayad PMCID: PMC1766334 Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis Michael I. Dorrell, Edith Aguilar, Lea Scheppke, Faith H. Barnett, and Martin Friedlander PMCID: PMC1764763 Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma M. E. Prince, R. Sivanandan, A. Kaczorowski, G. T. Wolf, M. J. Kaplan, P. Dalerba, I. L. Weissman, M. F. Clarke, and L. E. Ailles PMCID: PMC1783424 From the Cover:
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice Fredrik Bäckhed, Jill K. Manchester, Clay F. Semenkovich, and Jeffrey I. Gordon PMCID: PMC1764762 A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection Ying Huang, Huiying Yang, Brian B. Borg, Xiaowen Su, Shannon L. Rhodes, Kai Yang, Xiaomei Tong, George Tang, Charles D. Howell, Hugo R. Rosen, Chloe L. Thio, David L. Thomas, Harvey J. Alter, Ronda K. Sapp, and T. Jake Liang PMCID: PMC1783426 Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins Alessia Angelin, Tania Tiepolo, Patrizia Sabatelli, Paolo Grumati, Natascha Bergamin, Cristina Golfieri, Elisabetta Mattioli, Francesca Gualandi, Alessandra Ferlini, Luciano Merlini, Nadir M. Maraldi, Paolo Bonaldo, and Paolo Bernardi PMCID: PMC1783427 Microbiology From the Cover:
A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system Ivo G. Boneca, Olivier Dussurget, Didier Cabanes, Marie-Anne Nahori, Sandra Sousa, Marc Lecuit, Emmanuel Psylinakis, Vassilis Bouriotis, Jean-Pierre Hugot, Marco Giovannini, Anthony Coyle, John Bertin, Abdelkader Namane, Jean-Claude Rousselle, Nadège Cayet, Marie-Christine Prévost, Viviane Balloy, Michel Chignard, Dana J. Philpott, Pascale Cossart, and Stephen E. Girardin PMCID: PMC1766339 Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase Lindsay G. Stevenson, Kvido Strisovsky, Katy M. Clemmer, Shantanu Bhatt, Matthew Freeman, and Philip N. Rather PMCID: PMC1783354 A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate Larry A. Gallagher, Elizabeth Ramage, Michael A. Jacobs, Rajinder Kaul, Mitchell Brittnacher, and Colin Manoil PMCID: PMC1783355 HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcription Christine Goffinet, Ina Allespach, and Oliver T. Keppler PMCID: PMC1783356 A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine David G. Longstaff, Ross C. Larue, Joseph E. Faust, Anirban Mahapatra, Liwen Zhang, Kari B. Green-Church, and Joseph A. Krzycki PMCID: PMC1783357 Neuroscience Controlled expression of transgenes introduced by in vivo electroporation Takahiko Matsuda and Constance L. Cepko PMCID: PMC1764220 Differential distribution of NCX1 contributes to spine–dendrite compartmentalization in CA1 pyramidal cells Andrea Lőrincz, Balázs Rózsa, Gergely Katona, E. Sylvester Vizi, and Gábor Tamás PMCID: PMC1783359 A G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli Alexander T. Chesler, Dong-Jing Zou, Claire E. Le Pichon, Zita A. Peterlin, Glennis A. Matthews, Xin Pei, Michael C. Miller, and Stuart Firestein PMCID: PMC1783360 Further evidence that Whorfian effects are stronger in the right visual field than the left G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies PMCID: PMC1783370 Pharmacology In the regulation of cytochrome P450 genes, phenobarbital targets LKB1 for necessary activation of AMP-activated protein kinase Sharon M. Blättler, Franck Rencurel, Michel R. Kaufmann, and Urs A. Meyer PMCID: PMC1783361 Physiology A quantitative, theoretical framework for understanding mammalian sleep Van M. Savage and Geoffrey B. West PMCID: PMC1783362 Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo Catherine E. Amara, Eric G. Shankland, Sharon A. Jubrias, David J. Marcinek, Martin J. Kushmerick, and Kevin E. Conley PMCID: PMC1766336 A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel David A. Hill, Ajay D. Pillai, Fatima Nawaz, Karen Hayton, Lanxuan Doan, Godfrey Lisk, and Sanjay A. Desai PMCID: PMC1783364 Plant Biology Requirement of the C3HC4 zinc RING finger of the Arabidopsis PEX10 for photorespiration and leaf peroxisome contact with chloroplasts Uwe Schumann, Jakob Prestele, Henriette O'Geen, Robert Brueggeman, Gerhard Wanner, and Christine Gietl PMCID: PMC1783365 Arabidopsis systemic immunity uses conserved defense signaling pathways and is mediated by jasmonates William Truman, Mark H. Bennett, Ines Kubigsteltig, Colin Turnbull, and Murray Grant PMCID: PMC1783366 Conservation of B class gene expression in the second whorl of a basal grass and outgroups links the origin of lodicules and petals Clinton J. Whipple, Michael J. Zanis, Elizabeth A. Kellogg, and Robert J. Schmidt PMCID: PMC1783367 Social Sciences Anthropology Plants and people from the Early Neolithic to Shang periods in North China Gyoung-Ah Lee, Gary W. Crawford, Li Liu, and Xingcan Chen PMCID: PMC1764861 Economic Sciences A compensation election for binary social choice Ryan D. Oprea, Vernon L. Smith, and Abel M. Winn PMCID: PMC1783369 Psychology Further evidence that Whorfian effects are stronger in the right visual field than the left G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies PMCID: PMC1783370 Correction Correction for Shoshani et al., A proboscidean from the late Oligocene of Eritrea, a ‘missing link’ between early Elephantiformes and Elephantimorpha, and biogeographic implications PMCID: PMC1783371 Corrects: Jeheskel Shoshani, et al. A proboscidean from the late Oligocene of Eritrea, a “missing link” between early Elephantiformes and Elephantimorpha, and biogeographic implications. Proc Natl Acad Sci U S A. 2006 November 14; 103(46): 17296–17301. |
