| | This journal provides immediate access to some articles. Commentaries Tarp and Arp: How Chlamydia induces its own entry Joanne Engel PMCID: PMC454194 Connecting genes to metabolites by a systems biology approach Kirsi-Marja Oksman-Caldentey, Dirk Inzé, and Matej Orešič PMCID: PMC454195 Physical Sciences Applied Physical Sciences Localized chemical release from an artificial synapse chip Mark C. Peterman, Jaan Noolandi, Mark S. Blumenkranz, and Harvey A. Fishman PMCID: PMC454196 Chemistry Labeling of fusion proteins with synthetic fluorophores in live cells Antje Keppler, Horst Pick, Claudio Arrivoli, Horst Vogel, and Kai Johnsson PMCID: PMC454197 Activity-based probes for the proteomic profiling of metalloproteases Alan Saghatelian, Nadim Jessani, Arul Joseph, Mark Humphrey, and Benjamin F. Cravatt PMCID: PMC454150 Computer Sciences Stochastic computing with biomolecular automata Rivka Adar, Yaakov Benenson, Gregory Linshiz, Amit Rosner, Naftali Tishby, and Ehud Shapiro PMCID: PMC454388 Engineering A large-area, flexible pressure sensor matrix with organic field-effect transistors for artificial skin applications Takao Someya, Tsuyoshi Sekitani, Shingo Iba, Yusaku Kato, Hiroshi Kawaguchi, and Takayasu Sakurai PMCID: PMC454198 Biological Sciences Agricultural Sciences Rice yields decline with higher night temperature from global warming Shaobing Peng, Jianliang Huang, John E. Sheehy, Rebecca C. Laza, Romeo M. Visperas, Xuhua Zhong, Grace S. Centeno, Gurdev S. Khush, and Kenneth G. Cassman PMCID: PMC454199 Anthropology Auditory capacities in Middle Pleistocene humans from the Sierra de Atapuerca in Spain I. Martínez, M. Rosa, J.-L. Arsuaga, P. Jarabo, R. Quam, C. Lorenzo, A. Gracia, J.-M. Carretero, J.-M. Bermúdez de Castro, and E. Carbonell PMCID: PMC454200 Applied Biological Sciences A general approach for chemical labeling and rapid, spatially controlled protein inactivation Kevin M. Marks, Patrick D. Braun, and Garry P. Nolan PMCID: PMC454201 Biochemistry Stochastic computing with biomolecular automata Rivka Adar, Yaakov Benenson, Gregory Linshiz, Amit Rosner, Naftali Tishby, and Ehud Shapiro PMCID: PMC454388 Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity Dmitry V. Bugreev and Alexander V. Mazin PMCID: PMC454202 Structure of the periplasmic component of a bacterial drug efflux pump Matthew K. Higgins, Evert Bokma, Eva Koronakis, Colin Hughes, and Vassilis Koronakis PMCID: PMC454203 Activity-based probes for the proteomic profiling of metalloproteases Alan Saghatelian, Nadim Jessani, Arul Joseph, Mark Humphrey, and Benjamin F. Cravatt PMCID: PMC454150 The bioactive Taxol conformation on β-tubulin: Experimental evidence from highly active constrained analogs Thota Ganesh, Rebecca C. Guza, Susan Bane, Rudravajhala Ravindra, Natasha Shanker, Ami S. Lakdawala, James P. Snyder, and David G. I. Kingston PMCID: PMC454156 Small molecules targeting severe acute respiratory syndrome human coronavirus Chung-Yi Wu, Jia-Tsrong Jan, Shiou-Hwa Ma, Chih-Jung Kuo, Hsueh-Fen Juan, Yih-Shyun E. Cheng, Hsien-Hua Hsu, Hsuan-Cheng Huang, Douglass Wu, Ashraf Brik, Fu-Sen Liang, Rai-Shung Liu, Jim-Min Fang, Shui-Tein Chen, Po-Huang Liang, and Chi-Huey Wong PMCID: PMC454157 Engineered DsbC chimeras catalyze both protein oxidation and disulfide-bond isomerization in Escherichia coli: Reconciling two competing pathways Laura Segatori, Paul J. Paukstelis, Hiram F. Gilbert, and George Georgiou PMCID: PMC454158 From the Cover:
Yeast telomerase RNA: A flexible scaffold for protein subunits David C. Zappulla and Thomas R. Cech PMCID: PMC454382 The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration Deviprasad R. Gollapalli and Robert R. Rando PMCID: PMC454159 Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton Na Pi, Caren L. Freel Meyers, Michelle Pacholec, Christopher T. Walsh, and Julie A. Leary PMCID: PMC454160 Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity Hiroaki Daitoku, Mitsutoki Hatta, Hitomi Matsuzaki, Satoko Aratani, Takayuki Ohshima, Makoto Miyagishi, Toshihiro Nakajima, and Akiyoshi Fukamizu PMCID: PMC454161 Biophysics Coupling of retinal isomerization to the activation of rhodopsin Ashish B. Patel, Evan Crocker, Markus Eilers, Amiram Hirshfeld, Mordechai Sheves, and Steven O. Smith PMCID: PMC454162 Preferred peptide backbone conformations in the unfolded state revealed by the structure analysis of alanine-based (AXA) tripeptides in aqueous solution Fatma Eker, Kai Griebenow, Xiaolin Cao, Laurence A. Nafie, and Reinhard Schweitzer-Stenner PMCID: PMC454163 Microviscometry reveals reduced blood viscosity and altered shear rate and shear stress profiles in microvessels after hemodilution David S. Long, Michael L. Smith, Axel R. Pries, Klaus Ley, and Edward R. Damiano PMCID: PMC454164 Single-molecule enzymology of RNA: Essential functional groups impact catalysis from a distance David Rueda, Gregory Bokinsky, Maria M. Rhodes, Michael J. Rust, Xiaowei Zhuang, and Nils G. Walter PMCID: PMC454165 Cell Biology An endoplasmic reticulum trafficking signal prevents surface expression of a voltage- and Ca2+-activated K+ channel splice variant M. M. Zarei, M. Eghbali, A. Alioua, M. Song, H.-G. Knaus, E. Stefani, and L. Toro PMCID: PMC454166 From the Cover:
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases David Cortez, Gloria Glick, and Stephen J. Elledge PMCID: PMC454167 Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk–lipid droplets Sherry L. Ogg, Anne K. Weldon, Lorraine Dobbie, Andrew J. H. Smith, and Ian H. Mather PMCID: PMC454168 Apolipoprotein CIII promotes Ca2+-dependent β cell death in type 1 diabetes Lisa Juntti-Berggren, Essam Refai, Ioulia Appelskog, Mats Andersson, Gabriela Imreh, Nancy Dekki, Sabine Uhles, Lina Yu, William J. Griffiths, Sergei Zaitsev, Ingo Leibiger, Shao-Nian Yang, Gunilla Olivecrona, Hans Jörnvall, and Per-Olof Berggren PMCID: PMC454169 Developmental Biology Caste determination in a polyembryonic wasp involves inheritance of germ cells David M. Donnell, Laura S. Corley, Gang Chen, and Michael R. Strand PMCID: PMC454170 Ecology Species and functional group diversity independently influence biomass accumulation and its response to CO2 and N Peter B. Reich, David Tilman, Shahid Naeem, David S. Ellsworth, Johannes Knops, Joseph Craine, David Wedin, and Jared Trost PMCID: PMC454171 A community of unknown, endophytic fungi in western white pine Rebecca J. Ganley, Steven J. Brunsfeld, and George Newcombe PMCID: PMC454172 Evolution From the Cover:
Binocularity and brain evolution in primates R. A. Barton PMCID: PMC454173 Immunology CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: Induction of cytokine release and cytotoxicity against tumors and dendritic cells Simona Sivori, Michela Falco, Mariella Della Chiesa, Simona Carlomagno, Massimo Vitale, Lorenzo Moretta, and Alessandro Moretta PMCID: PMC454174 Donor-specific transplantation tolerance: The paradoxical behavior of CD4+CD25+ T cells Luis Graca, Alain Le Moine, Chun-Yen Lin, Paul J. Fairchild, Stephen P. Cobbold, and Herman Waldmann PMCID: PMC454175 Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin Misao Matsushita, Akiko Matsushita, Yuichi Endo, Munehiro Nakata, Naoya Kojima, Tsuguo Mizuochi, and Teizo Fujita PMCID: PMC454176 Medical Sciences Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis Atsushi Sanbe, Hanna Osinska, Jeffrey E. Saffitz, Charles G. Glabe, Rakez Kayed, Alina Maloyan, and Jeffrey Robbins PMCID: PMC454177 NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis Debajit K. Biswas, Qian Shi, Shanon Baily, Ian Strickland, Sankar Ghosh, Arthur B. Pardee, and J. Dirk Iglehart PMCID: PMC454178 Effects of cigarette smoke on the human airway epithelial cell transcriptome Avrum Spira, Jennifer Beane, Vishal Shah, Gang Liu, Frank Schembri, Xuemei Yang, John Palma, and Jerome S. Brody PMCID: PMC454179 Neutralizing antibody response during acute and chronic hepatitis C virus infection C. Logvinoff, M. E. Major, D. Oldach, S. Heyward, A. Talal, P. Balfe, S. M. Feinstone, H. Alter, C. M. Rice, and J. A. McKeating PMCID: PMC454180 Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement Holger Thiele, Masahiro Sakano, Hiroshi Kitagawa, Kazuyuki Sugahara, Anna Rajab, Wolfgang Höhne, Heide Ritter, Gundula Leschik, Peter Nürnberg, and Stefan Mundlos PMCID: PMC454181 Microbiology An in vivo assay identifies changes in residue accessibility on mechanosensitive channel gating Jessica L. Bartlett, Gal Levin, and Paul Blount PMCID: PMC454182 From the Cover:
A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin D. R. Clifton, K. A. Fields, S. S. Grieshaber, C. A. Dooley, E. R. Fischer, D. J. Mead, R. A. Carabeo, and T. Hackstadt PMCID: PMC454183 Neuroscience Localized chemical release from an artificial synapse chip Mark C. Peterman, Jaan Noolandi, Mark S. Blumenkranz, and Harvey A. Fishman PMCID: PMC454196 Notch signaling in Drosophila long-term memory formation Xuecai Ge, Frances Hannan, Zuolei Xie, Chunhua Feng, Tim Tully, Haimeng Zhou, Zuoping Xie, and Yi Zhong PMCID: PMC454384 No evidence for new dopaminergic neurons in the adult mammalian substantia nigra Helena Frielingsdorf, Katherine Schwarz, Patrik Brundin, and Paul Mohapel PMCID: PMC454184 Phosphatase inhibitors remove the run-down of γ-aminobutyric acid type A receptors in the human epileptic brain E. Palma, D. A. Ragozzino, S. Di Angelantonio, G. Spinelli, F. Trettel, A. Martinez-Torres, G. Torchia, A. Arcella, G. Di Gennaro, P. P. Quarato, V. Esposito, G. Cantore, R. Miledi, and F. Eusebi PMCID: PMC454185 Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor Daniela Marazziti, Elisabetta Golini, Silvia Mandillo, Armando Magrelli, Walter Witke, Rafaele Matteoni, and Glauco P. Tocchini-Valentini PMCID: PMC454186 A fluorophore attached to nicotinic acetylcholine receptor βM2 detects productive binding of agonist to the αδ site David S. Dahan, Mohammed I. Dibas, E. James Petersson, Vincent C. Auyeung, Baron Chanda, Francisco Bezanilla, Dennis A. Dougherty, and Henry A. Lester PMCID: PMC454187 Pharmacology Selective facilitation of sexual solicitation in the female rat by a melanocortin receptor agonist James G. Pfaus, Annette Shadiack, Tanya Van Soest, Maric Tse, and Perry Molinoff PMCID: PMC454387 Plant Biology From the Cover:
Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana Masami Yokota Hirai, Mitsuru Yano, Dayan B. Goodenowe, Shigehiko Kanaya, Tomoko Kimura, Motoko Awazuhara, Masanori Arita, Toru Fujiwara, and Kazuki Saito PMCID: PMC454188 A probable Na+(K+)/H+ exchanger on the chloroplast envelope functions in pH homeostasis and chloroplast development in Arabidopsis thaliana Chun-Peng Song, Yan Guo, Quansheng Qiu, Georgina Lambert, David W. Galbraith, André Jagendorf, and Jian-Kang Zhu PMCID: PMC454189 Six nonnodulating plant mutants defective for Nod factor-induced transcriptional changes associated with the legume-rhizobia symbiosis Raka M. Mitra, Sidney L. Shaw, and Sharon R. Long PMCID: PMC454190 Population Biology Methicillin-resistant Staphylococcus aureus in hospitals and the community: Stealth dynamics and control catastrophes B. S. Cooper, G. F. Medley, S. P. Stone, C. C. Kibbler, B. D. Cookson, J. A. Roberts, G. Duckworth, R. Lai, and S. Ebrahim PMCID: PMC454191 Diversity in pathogenicity can cause outbreaks of meningococcal disease Nico Stollenwerk, Martin C. J. Maiden, and Vincent A. A. Jansen PMCID: PMC454192 Social Sciences Social Sciences The evolution of culture: From primate social learning to human culture Laureano Castro and Miguel A. Toro PMCID: PMC454193 |
