| | This journal provides immediate access to some articles. QnAs QnAs with Randy Schekman Nick Zagorski PMCID: PMC1748144 This Week in PNAS Proc Natl Acad Sci U S A. 2006 December 12; 103(50): 18877–18878. doi: 10.1073/iti5006103.PMCID: PMC1748142 Commentary Flavivirus nonstructural protein NS1: Complementary surprises Jacob J. Schlesinger PMCID: PMC1748143 Physical Sciences Applied Physical Sciences Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence Paul Cherukuri, Christopher J. Gannon, Tonya K. Leeuw, Howard K. Schmidt, Richard E. Smalley, Steven A. Curley, and R. Bruce Weisman PMCID: PMC1665645 Chemistry Note on the energy density in the solvent induced by a solute B. Widom and Dor Ben-Amotz PMCID: PMC1748146 Two-dimensional vibrational optical probes for peptide fast folding investigation Wei Zhuang, Darius Abramavicius, and Shaul Mukamel PMCID: PMC1748155 Engineering Distant touch hydrodynamic imaging with an artificial lateral line Yingchen Yang, Jack Chen, Jonathan Engel, Saunvit Pandya, Nannan Chen, Craig Tucker, Sheryl Coombs, Douglas L. Jones, and Chang Liu PMCID: PMC1748147 Environmental Sciences Production of hydrogen peroxide in the atmosphere of a Snowball Earth and the origin of oxygenic photosynthesis Mao-Chang Liang, Hyman Hartman, Robert E. Kopp, Joseph L. Kirschvink, and Yuk L. Yung PMCID: PMC1672611 Physics A statistical approach to close packing of elastic rods and to DNA packaging in viral capsids E. Katzav, M. Adda-Bedia, and A. Boudaoud PMCID: PMC1748149 Biological Sciences Agricultural Sciences Dynamics of global transcriptome in bovine matured oocytes and preimplantation embryos M. Misirlioglu, G. P. Page, H. Sagirkaya, A. Kaya, J. J. Parrish, N. L. First, and E. Memili PMCID: PMC1748150 Applied Biological Sciences Wide-field subdiffraction imaging by accumulated binding of diffusing probes Alexey Sharonov and Robin M. Hochstrasser PMCID: PMC1748151 Biochemistry Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex Christoph H. Hagemeier, Markus K ![[r with umlaut]](corehtml/pmc/pmcents/x0072x0308.gif) er, Rudolf K. Thauer, Eberhard Warkentin, and Ulrich Ermler PMCID: PMC1748152 RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea Jing Yuan, Sotiria Palioura, Juan Carlos Salazar, Dan Su, Patrick O'Donoghue, Michael J. Hohn, Alexander Machado Cardoso, William B. Whitman, and Dieter Söll PMCID: PMC1748153 Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors Andrew C. Paoletti, Tari J. Parmely, Chieri Tomomori-Sato, Shigeo Sato, Dongxiao Zhu, Ronald C. Conaway, Joan Weliky Conaway, Laurence Florens, and Michael P. Washburn PMCID: PMC1672612 Biophysics A statistical approach to close packing of elastic rods and to DNA packaging in viral capsids E. Katzav, M. Adda-Bedia, and A. Boudaoud PMCID: PMC1748149 Two-dimensional vibrational optical probes for peptide fast folding investigation Wei Zhuang, Darius Abramavicius, and Shaul Mukamel PMCID: PMC1748155 Dynamics of allosteric transitions in GroEL Changbong Hyeon, George H. Lorimer, and D. Thirumalai PMCID: PMC1748156 From the Cover:
Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR Alexander N. Volkov, Jonathan A. R. Worrall, Elodie Holtzmann, and Marcellus Ubbink PMCID: PMC1748157 Regions of IκBα that are critical for its inhibition of NF-κB·DNA interaction fold upon binding to NF-κB Stephanie M. E. Truhlar, Justin W. Torpey, and Elizabeth A. Komives PMCID: PMC1748158 Cell Biology MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells Joan C. Ritland Politz, Fan Zhang, and Thoru Pederson PMCID: PMC1748159 Expression of Aedes trypsin-modulating oostatic factor on the virion of TMV: A potential larvicide Dov Borovsky, Shailaja Rabindran, William O. Dawson, Charles A. Powell, Donna A. Iannotti, Timothy J. Morris, Jeffry Shabanowitz, Donald F. Hunt, Hendrik L. DeBondt, and Arnold DeLoof PMCID: PMC1748160 The Spemann organizer gene, Goosecoid, promotes tumor metastasis Kimberly A. Hartwell, Beth Muir, Ferenc Reinhardt, Anne E. Carpenter, Dennis C. Sgroi, and Robert A. Weinberg PMCID: PMC1748161 Differential effects of spermatogenesis and fertility in mice lacking androgen receptor in individual testis cells Meng-Yin Tsai, Shauh-Der Yeh, Ruey-Sheng Wang, Shuyuan Yeh, Caixia Zhang, Hung-Yun Lin, Chii-Ruey Tzeng, and Chawnshang Chang PMCID: PMC1748162 FHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells Francesca Bianchi, Alessandra Magnifico, Clelia Olgiati, Nicola Zanesi, Yuri Pekarsky, Elda Tagliabue, Carlo Maria Croce, Sylvie Ménard, and Manuela Campiglio PMCID: PMC1679754 Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor Seon-Joo Yoon, Ken-ichi Nakayama, Toshiyuki Hikita, Kazuko Handa, and Sen-itiroh Hakomori PMCID: PMC1748164 Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton Björn F. Lillemeier, Janet R. Pfeiffer, Zurab Surviladze, Bridget S. Wilson, and Mark M. Davis PMCID: PMC1681352 Developmental Biology Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property Ashutosh P. Jadhav, Seo-Hee Cho, and Constance L. Cepko PMCID: PMC1682012 Dominance of SOX9 function over RUNX2 during skeletogenesis Guang Zhou, Qiping Zheng, Feyza Engin, Elda Munivez, Yuqing Chen, Eiman Sebald, Deborah Krakow, and Brendan Lee PMCID: PMC1748167 Ecology Rapid decay of tree-community composition in Amazonian forest fragments William F. Laurance, Henrique E. M. Nascimento, Susan G. Laurance, Ana Andrade, José E. L. S. Ribeiro, Juan Pablo Giraldo, Thomas E. Lovejoy, Richard Condit, Jerome Chave, Kyle E. Harms, and Sammya D'Angelo PMCID: PMC1682011 A robust measure of food web intervality Daniel B. Stouffer, Juan Camacho, and Luís A. Nunes Amaral PMCID: PMC1748169 Evolution Developmental plasticity mirrors differences among taxa in spadefoot toads linking plasticity and diversity Ivan Gomez-Mestre and Daniel R. Buchholz PMCID: PMC1748170 Almost all human genes resulted from ancient duplication Roy J. Britten PMCID: PMC1748171 Genetics From the Cover:
Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns Timothy R. Lezon, Jayanth R. Banavar, Marek Cieplak, Amos Maritan, and Nina V. Fedoroff PMCID: PMC1748172 Genomewide screens for Escherichia coli genes affecting growth of T7 bacteriophage Udi Qimron, Boriana Marintcheva, Stanley Tabor, and Charles C. Richardson PMCID: PMC1748173 A synthetic phage λ regulatory circuit Shota Atsumi and John W. Little PMCID: PMC1748174 Immunology Viral protease cleavage of inhibitor of κBα triggers host cell apoptosis Carlos Zaragoza, Marta Saura, Elizaveta Y. Padalko, Ester Lopez-Rivera, Tania R. Lizarbe, Santiago Lamas, and Charles J. Lowenstein PMCID: PMC1748175 Identification of a pathogenic antibody response to native myelin oligodendrocyte glycoprotein in multiple sclerosis Dun Zhou, Rajneesh Srivastava, Stefan Nessler, Verena Grummel, Norbert Sommer, Wolfgang Brück, Hans-Peter Hartung, Christine Stadelmann, and Bernhard Hemmer PMCID: PMC1748176 Medical Sciences Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence Paul Cherukuri, Christopher J. Gannon, Tonya K. Leeuw, Howard K. Schmidt, Richard E. Smalley, Steven A. Curley, and R. Bruce Weisman PMCID: PMC1665645 A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions T. S. Wehrman, W. J. Raab, C. L. Casipit, R. Doyonnas, J. H. Pomerantz, and H. M. Blau PMCID: PMC1748177 From the Cover:
Crosstalk between peroxisome proliferator-activated receptor δ and VEGF stimulates cancer progression Dingzhi Wang, Haibin Wang, Yong Guo, Wei Ning, Sharada Katkuri, Walter Wahli, Beatrice Desvergne, Sudhansu K. Dey, and Raymond N. DuBois PMCID: PMC1748178 Correction of hemophilia as a proof of concept for treatment of monogenic diseases by fetal spleen transplantation Anna Aronovich, Dalit Tchorsh, Helena Katchman, Smadar Eventov-Friedman, Elias Shezen, Uri Martinowitz, Bruce R. Blazar, Sivan Cohen, Orna Tal, and Yair Reisner PMCID: PMC1682010 Thymic rejuvenation and the induction of tolerance by adult thymic grafts Shuji Nobori, Akira Shimizu, Masayoshi Okumi, Emma Samelson-Jones, Adam Griesemer, Atsushi Hirakata, David H. Sachs, and Kazuhiko Yamada PMCID: PMC1748180 Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response Ramaswamy Ramchandran, Takanobu Takezako, Yasser Saad, Linda Stull, Bruno Fink, Hirotsugu Yamada, Sergey Dikalov, David G. Harrison, Christine Moravec, and Sadashiva S. Karnik PMCID: PMC1748181 Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange Norbert Weissmann, Alexander Dietrich, Beate Fuchs, Hermann Kalwa, Mahmut Ay, Rio Dumitrascu, Andrea Olschewski, Ursula Storch, Michael Mederos y Schnitzler, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly, Olaf Pinkenburg, Werner Seeger, Friedrich Grimminger, and Thomas Gudermann PMCID: PMC1748182 Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease Weiqiang Gao, Patricia J. Anderson, Elaine M. Majerus, Elodee A. Tuley, and J. Evan Sadler PMCID: PMC1681350 Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes Giuseppe Legname, Hoang-Oanh B. Nguyen, David Peretz, Fred E. Cohen, Stephen J. DeArmond, and Stanley B. Prusiner PMCID: PMC1748184 Microbiology From the Cover:
West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H Kyung Min Chung, M. Kathryn Liszewski, Grant Nybakken, Alan E. Davis, R. Reid Townsend, Daved H. Fremont, John P. Atkinson, and Michael S. Diamond PMCID: PMC1664712 Human cytomegalovirus pUL37x1 induces the release of endoplasmic reticulum calcium stores Ronit Sharon-Friling, Joseph Goodhouse, Anamaris M. Colberg-Poley, and Thomas Shenk PMCID: PMC1748185 Influenza virus pleiomorphy characterized by cryoelectron tomography Audray Harris, Giovanni Cardone, Dennis C. Winkler, J. Bernard Heymann, Matthew Brecher, Judith M. White, and Alasdair C. Steven PMCID: PMC1748186 The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation Peter Meiser, Helge B. Bode, and Rolf Müller PMCID: PMC1748187 Balancing selection and the evolution of functional polymorphism in Old World monkey TRIM5α Ruchi M. Newman, Laura Hall, Michelle Connole, Guo-Lin Chen, Shuji Sato, Eloisa Yuste, William Diehl, Eric Hunter, Amitinder Kaur, Gregory M. Miller, and Welkin E. Johnson PMCID: PMC1679755 Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding Alessia Zamborlini, Yoshiko Usami, Sheli R. Radoshitzky, Elena Popova, Giorgio Palu, and Heinrich Göttlinger PMCID: PMC1748189 Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung Sruti DebRoy, Jenny Dao, Maria Söderberg, Ombeline Rossier, and Nicholas P. Cianciotto PMCID: PMC1748190 Neuroscience Distant touch hydrodynamic imaging with an artificial lateral line Yingchen Yang, Jack Chen, Jonathan Engel, Saunvit Pandya, Nannan Chen, Craig Tucker, Sheryl Coombs, Douglas L. Jones, and Chang Liu PMCID: PMC1748147 Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy Alwin Klaassen, Joseph Glykys, Jamie Maguire, Cesar Labarca, Istvan Mody, and Jim Boulter PMCID: PMC1681351 Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go Sungho Ghil, Jung-Mi Choi, Sung-Soo Kim, Young-Don Lee, Yanhong Liao, Lutz Birnbaumer, and Haeyoung Suh-Kim PMCID: PMC1682014 A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder Chun-Hyung Kim, Maureen K. Hahn, Yoosook Joung, Susan L. Anderson, Angela H. Steele, Michelle S. Mazei-Robinson, Ian Gizer, Martin H. Teicher, Bruce M. Cohen, David Robertson, Irwin D. Waldman, Randy D. Blakely, and Kwang-Soo Kim PMCID: PMC1748193 From the Cover:
Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoids Christian Mirescu, Jennifer D. Peters, Liron Noiman, and Elizabeth Gould PMCID: PMC1748194 ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease Hoon Ryu, Junghee Lee, Sean W. Hagerty, Byoung Yul Soh, Sara E. McAlpin, Kerry A. Cormier, Karen M. Smith, and Robert J. Ferrante PMCID: PMC1748195 Proteolytic processing of SDF-1α reveals a change in receptor specificity mediating HIV-associated neurodegeneration David Vergote, Georgina S. Butler, Martine Ooms, Jennifer H. Cox, Claudia Silva, Morley D. Hollenberg, Jack H. Jhamandas, Christopher M. Overall, and Christopher Power PMCID: PMC1748196 GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons Sara J. Aton, James E. Huettner, Martin Straume, and Erik D. Herzog PMCID: PMC1748197 Pharmacology Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms Sunil Laxman, Aaron Riechers, Martin Sadilek, Frank Schwede, and Joseph A. Beavo PMCID: PMC1748198 Plant Biology RAR1, a central player in plant immunity, is targeted by Pseudomonas syringae effector AvrB Yulei Shang, Xinyan Li, Haitao Cui, Ping He, Roger Thilmony, Satya Chintamanani, Julie Zwiesler-Vollick, Suresh Gopalan, Xiaoyan Tang, and Jian-Min Zhou PMCID: PMC1748199 The Arabidopsis NRT1.1 transporter participates in the signaling pathway triggering root colonization of nitrate-rich patches Tony Remans, Philippe Nacry, Marjorie Pervent, Sophie Filleur, Eugene Diatloff, Emmanuelle Mounier, Pascal Tillard, Brian G. Forde, and Alain Gojon PMCID: PMC1748200 Sustainability Science Rapid decay of tree-community composition in Amazonian forest fragments William F. Laurance, Henrique E. M. Nascimento, Susan G. Laurance, Ana Andrade, José E. L. S. Ribeiro, Juan Pablo Giraldo, Thomas E. Lovejoy, Richard Condit, Jerome Chave, Kyle E. Harms, and Sammya D'Angelo PMCID: PMC1682011 Corrections Correction for Albina et al., Depth sectioning with the aberration-corrected scanning transmission electron microscope PMCID: PMC1748201 Corrects: Albina Y. Borisevich, et al. Depth sectioning with the aberration-corrected scanning transmission electron microscope. Proc Natl Acad Sci U S A. 2006 February 28; 103(9): 3044–3048. Correction for Wang et al., A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans PMCID: PMC1748202 Corrects: Hongyan Wang, et al. From the Cover:
A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans. Proc Natl Acad Sci U S A. 2006 September 5; 103(36): 13463–13467. Correction for Pellegata et al., Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans PMCID: PMC1748203 Corrects: Natalia S. Pellegata, et al. Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans. Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15558–15563. Retraction Retraction for Coldren et al., Flexible bilayers with spontaneous curvature lead to lamellar gels and spontaneous vesicles Solomon H. Snyder and David G. Whitten PMCID: PMC1748204 Retracts: Bret A. Coldren, et al. Flexible bilayers with spontaneous curvature lead to lamellar gels and spontaneous vesicles. Proc Natl Acad Sci U S A. 2006 February 21; 103(8): 2524–2529. |
