| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 November 28; 103(48): 18027–18028. doi: 10.1073/iti4806103.PMCID: PMC1838698 Commentaries Charting uncertainty about ant origins Ross H. Crozier PMCID: PMC1838699 Multiple independent origins of sex chromosomes in amniotes Eric J. Vallender and Bruce T. Lahn PMCID: PMC1838700 Random mutations, selected mutations: A PIN opens the door to new genetic landscapes Christoph A. Klein PMCID: PMC1838701 Physical Sciences Chemistry INAUGURAL ARTICLE by a Recently Elected Academy Member: Organic haze on Titan and the early Earth Melissa G. Trainer, Alexander A. Pavlov, H. Langley DeWitt, Jose L. Jimenez, Christopher P. McKay, Owen B. Toon, and Margaret A. Tolbert PMCID: PMC1838702 Charge transfer through DNA nanoscaled assembly programmable with DNA building blocks Yasuko Osakada, Kiyohiko Kawai, Mamoru Fujitsuka, and Tetsuro Majima PMCID: PMC1838708 Engineering Polymeric triple-shape materials I. Bellin, S. Kelch, R. Langer, and A. Lendlein PMCID: PMC1838703 Physics Laser trapping in anisotropic fluids and polarization-controlled particle dynamics Ivan I. Smalyukh, Aliaksandr V. Kachynski, Andrey N. Kuzmin, and Paras N. Prasad PMCID: PMC1643843 Biological Sciences Applied Biological Sciences From the Cover:
Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol Ganesan Sunilkumar, LeAnne M. Campbell, Lorraine Puckhaber, Robert D. Stipanovic, and Keerti S. Rathore PMCID: PMC1838705 The use of transcriptional profiles to predict adult mosquito age under field conditions Peter E. Cook, Leon E. Hugo, Iñaki Iturbe-Ormaetxe, Craig R. Williams, Stephen F. Chenoweth, Scott A. Ritchie, Peter A. Ryan, Brian H. Kay, Mark W. Blows, and Scott L. O'Neill PMCID: PMC1838706 Characterization of a cancer/testis (CT) antigen gene family capable of eliciting humoral response in cancer patients Raphael B. Parmigiani, Fabiana Bettoni, Maria D. Vibranovski, Marilene H. Lopes, Waleska K. Martins, Isabela W. Cunha, Fernando A. Soares, Andrew J. G. Simpson, Sandro J. de Souza, and Anamaria A. Camargo PMCID: PMC1838707 Biochemistry Charge transfer through DNA nanoscaled assembly programmable with DNA building blocks Yasuko Osakada, Kiyohiko Kawai, Mamoru Fujitsuka, and Tetsuro Majima PMCID: PMC1838708 Ribosomal tethering and clustering as mechanisms for translation initiation Stephen A. Chappell, Gerald M. Edelman, and Vincent P. Mauro PMCID: PMC1838709 Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer Chad A. Dumstorf, Alan B. Clark, Qingcong Lin, Grace E. Kissling, Tao Yuan, Raju Kucherlapati, W. Glenn McGregor, and Thomas A. Kunkel PMCID: PMC1838710 Costs and benefits of processivity in enzymatic degradation of recalcitrant polysaccharides Svein J. Horn, Pawel Sikorski, Jannicke B. Cederkvist, Gustav Vaaje-Kolstad, Morten Sørlie, Bjørnar Synstad, Gert Vriend, Kjell M. Vårum, and Vincent G. H. Eijsink PMCID: PMC1838711 Emergence of the universal genetic code imprinted in an RNA record Michael J. Hohn, Hee-Sung Park, Patrick O'Donoghue, Michael Schnitzbauer, and Dieter Söll PMCID: PMC1838712 The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity Michelle A. Emrick, Thomas Lee, Paul J. Starkey, Marc C. Mumby, Katheryn A. Resing, and Natalie G. Ahn PMCID: PMC1838713 Human SHPRH is a ubiquitin ligase for Mms2–Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen Ildiko Unk, Ildikó Hajdú, Károly Fátyol, Barnabás Szakál, András Blastyák, Vladimir Bermudez, Jerard Hurwitz, Louise Prakash, Satya Prakash, and Lajos Haracska PMCID: PMC1838714 Biophysics Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains Sarah Batey and Jane Clarke PMCID: PMC1636339 3D structure of amyloid protofilaments of β2-microglobulin fragment probed by solid-state NMR Kentaro Iwata, Toshimichi Fujiwara, Yoh Matsuki, Hideo Akutsu, Satoshi Takahashi, Hironobu Naiki, and Yuji Goto PMCID: PMC1838716 Cell Biology Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules Anthony K. L. Leung, J. Mauro Calabrese, and Phillip A. Sharp PMCID: PMC1838717 A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms Hirotoshi Matsui, Victoria E. Wagner, David B. Hill, Ute E. Schwab, Troy D. Rogers, Brian Button, Russell M. Taylor, II, Richard Superfine, Michael Rubinstein, Barbara H. Iglewski, and Richard C. Boucher PMCID: PMC1838718 H2AX chromatin structures and their response to DNA damage revealed by 4Pi microscopy Jörg Bewersdorf, Brian T. Bennett, and Kendall L. Knight PMCID: PMC1636994 Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function Danny M. Chou and Stephen J. Elledge PMCID: PMC1654129 Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression Xiaoyi Hu, Anthony Addlagatta, Jun Lu, Brian W. Matthews, and Jun O. Liu PMCID: PMC1838721 Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity Eoin P. Cummins, Edurne Berra, Katrina M. Comerford, Amandine Ginouves, Kathleen T. Fitzgerald, Fergal Seeballuck, Catherine Godson, Jens E. Nielsen, Paul Moynagh, Jacques Pouyssegur, and Cormac T. Taylor PMCID: PMC1643842 Developmental Biology Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos Kate Monzo, Ophelia Papoulas, Greg T. Cantin, Yan Wang, John R. Yates, III, and John C. Sisson PMCID: PMC1838723 Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes Andrey A. Sharov, Tatyana Y. Sharova, Andrei N. Mardaryev, Alice Tommasi di Vignano, Ruzanna Atoyan, Lorin Weiner, Shi Yang, Janice L. Brissette, G. Paolo Dotto, and Vladimir A. Botchkarev PMCID: PMC1838724 Evolution From the Cover:
Evaluating alternative hypotheses for the early evolution and diversification of ants Seán G. Brady, Ted R. Schultz, Brian L. Fisher, and Philip S. Ward PMCID: PMC1838725 Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage Patrick D. Evans, Nitzan Mekel-Bobrov, Eric J. Vallender, Richard R. Hudson, and Bruce T. Lahn PMCID: PMC1635020 Drosophila flies in “Evolution Canyon” as a model for incipient sympatric speciation Abraham Korol, Eugenia Rashkovetsky, Konstantin Iliadi, and Eviatar Nevo PMCID: PMC1838727 Genetics From the Cover:
Evidence for different origin of sex chromosomes in snakes, birds, and mammals and step-wise differentiation of snake sex chromosomes Kazumi Matsubara, Hiroshi Tarui, Michihisa Toriba, Kazuhiko Yamada, Chizuko Nishida-Umehara, Kiyokazu Agata, and Yoichi Matsuda PMCID: PMC1838728 Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants Kristina H. Schmidt and Richard D. Kolodner PMCID: PMC1838729 Immunology Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner Leonard L. Dragone, Margaret D. Myers, Carmen White, Shyam Gadwal, Tomasz Sosinowski, Hua Gu, and Arthur Weiss PMCID: PMC1838730 Influence of dominant HIV-1 epitopes on HLA-A3/peptide complex formation Judith Racape, Francine Connan, Johan Hoebeke, Jeannine Choppin, and Jean-Gérard Guillet PMCID: PMC1654130 Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion Jinfang Zhu, Dragana Jankovic, Alex Grinberg, Liying Guo, and William E. Paul PMCID: PMC1654136 Direct peptide-regulatable interactions between MHC class I molecules and tapasin Syed Monem Rizvi and Malini Raghavan PMCID: PMC1838733 Immunoglobulin G signaling activates lysosome/phagosome docking Vishal Trivedi, Shao C. Zhang, Adam B. Castoreno, Walter Stockinger, Eugenie C. Shieh, Jatin M. Vyas, Eva-Maria Frickel, and Axel Nohturfft PMCID: PMC1838734 A 50-kDa ERK-like protein is up-regulated by a dual altered peptide ligand that suppresses myasthenia gravis-associated responses Hava Ben-David, Badiga Venkata Aruna, Rony Seger, Michael Sela, and Edna Mozes PMCID: PMC1838735 Medical Sciences From the Cover:
Human cancers express a mutator phenotype Jason H. Bielas, Keith R. Loeb, Brian P. Rubin, Lawrence D. True, and Lawrence A. Loeb PMCID: PMC1636340 Sustained high-titer antibody responses induced by conjugating a malarial vaccine candidate to outer-membrane protein complex Yimin Wu, Craig Przysiecki, Elizabeth Flanagan, Sheila N. Bello-Irizarry, Roxana Ionescu, Olga Muratova, Gelu Dobrescu, Lynn Lambert, David Keister, Yvette Rippeon, Carole A. Long, Li Shi, Michael Caulfield, Alan Shaw, Allan Saul, John Shiver, and Louis H. Miller PMCID: PMC1636993 Alanine–glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer Eduardo C. Salido, Xiao M. Li, Yang Lu, Xia Wang, Alfredo Santana, Namita Roy-Chowdhury, Armando Torres, Larry J. Shapiro, and Jayanta Roy-Chowdhury PMCID: PMC1838738 A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure Eva van Rooij, Lillian B. Sutherland, Ning Liu, Andrew H. Williams, John McAnally, Robert D. Gerard, James A. Richardson, and Eric N. Olson PMCID: PMC1838739 NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth Teresa Palomero, Wei Keat Lim, Duncan T. Odom, Maria Luisa Sulis, Pedro J. Real, Adam Margolin, Kelly C. Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P. Weng, Jon C. Aster, Francois Sigaux, Jean Soulier, A. Thomas Look, Richard A. Young, Andrea Califano, and Adolfo A. Ferrando PMCID: PMC1838740 From the Cover:
Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome Bryan E. McGill, Sharyl F. Bundle, Murat B. Yaylaoglu, James P. Carson, Christina Thaller, and Huda Y. Zoghbi PMCID: PMC1636379 Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men Kitt Falk Petersen, Sylvie Dufour, Jing Feng, Douglas Befroy, James Dziura, Chiara Dalla Man, Claudio Cobelli, and Gerald I. Shulman PMCID: PMC1693873 Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI Bastiaan Driehuys, Gary P. Cofer, Jim Pollaro, Julie Boslego Mackel, Laurence W. Hedlund, and G. Allan Johnson PMCID: PMC1838742 Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice Sandra B. Haudek, Ying Xia, Peter Huebener, John M. Lee, Signe Carlson, Jeff R. Crawford, Darrell Pilling, Richard H. Gomer, JoAnn Trial, Nikolaos G. Frangogiannis, and Mark L. Entman PMCID: PMC1643845 Change in chronic disability from 1982 to 2004/2005 as measured by long-term changes in function and health in the U.S. elderly population Kenneth G. Manton, XiLiang Gu, and Vicki L. Lamb PMCID: PMC1635981 Microbiology Pathogen escape from host immunity by a genome program for antigenic variation Alan G. Barbour, Qiyuan Dai, Blanca I. Restrepo, Herbert G. Stoenner, and Steven A. Frank PMCID: PMC1635980 Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum symbiosum Steven J. Hallam, Konstantinos T. Konstantinidis, Nik Putnam, Christa Schleper, Yoh-ichi Watanabe, Junichi Sugahara, Christina Preston, José de la Torre, Paul M. Richardson, and Edward F. DeLong PMCID: PMC1643844 Murine cytomegalovirus encodes a stable intron that facilitates persistent replication in the mouse Caroline A. Kulesza and Thomas Shenk PMCID: PMC1838746 Neuroscience Poly(ADP-ribose) (PAR) polymer is a death signal Shaida A. Andrabi, No Soo Kim, Seong-Woon Yu, Hongmin Wang, David W. Koh, Masayuki Sasaki, Judith A. Klaus, Takashi Otsuka, Zhizheng Zhang, Raymond C. Koehler, Patricia D. Hurn, Guy G. Poirier, Valina L. Dawson, and Ted M. Dawson PMCID: PMC1838747 Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death Seong-Woon Yu, Shaida A. Andrabi, Hongmin Wang, No Soo Kim, Guy G. Poirier, Ted M. Dawson, and Valina L. Dawson PMCID: PMC1838748 Mst3b, a purine-sensitive Ste20-like protein kinase, regulates axon outgrowth N. Irwin, Y.-M. Li, J. E. O'Toole, and L. I. Benowitz PMCID: PMC1838749 Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration Jian Luo, Amy H. Lin, Eliezer Masliah, and Tony Wyss-Coray PMCID: PMC1838750 Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size Ruud F. G. Toonen, Keimpe Wierda, Michèle S. Sons, Heidi de Wit, L. Niels Cornelisse, Arjen Brussaard, Jaap J. Plomp, and Matthijs Verhage PMCID: PMC1838751 Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin Wenhua Liu, Eunice Y. Yuen, Patrick B. Allen, Jian Feng, Paul Greengard, and Zhen Yan PMCID: PMC1838752 Physiology Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel Erik-Jan Kamsteeg, Giel Hendriks, Michelle Boone, Irene B. M. Konings, Viola Oorschot, Peter van der Sluijs, Judith Klumperman, and Peter M. T. Deen PMCID: PMC1838753 Role of estrogen receptor β in uterine stroma and epithelium: Insights from estrogen receptor β−/− mice Osamu Wada-Hiraike, Haruko Hiraike, Hiroko Okinaga, Otabek Imamov, Rodrigo P. A. Barros, Andrea Morani, Yoko Omoto, Margaret Warner, and Jan-Åke Gustafsson PMCID: PMC1838754 Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism Wolfgang Boehmerle, Ute Splittgerber, Michael B. Lazarus, Kathleen M. McKenzie, David G. Johnston, David J. Austin, and Barbara E. Ehrlich PMCID: PMC1838755 Plant Biology The voltage-dependent anion channel, a major component of the tRNA import machinery in plant mitochondria Thalia Salinas, Anne-Marie Duchêne, Ludovic Delage, Stefan Nilsson, Elzbieta Glaser, Marlyse Zaepfel, and Laurence Maréchal-Drouard PMCID: PMC1838756 A second isoform of the ferredoxin:NADP oxidoreductase generated by an in-frame initiation of translation Jean-Claude Thomas, Bettina Ughy, Bernard Lagoutte, and Ghada Ajlani PMCID: PMC1838757 Social Sciences Social Sciences Change in chronic disability from 1982 to 2004/2005 as measured by long-term changes in function and health in the U.S. elderly population Kenneth G. Manton, XiLiang Gu, and Vicki L. Lamb PMCID: PMC1635981 Correction Correction for Ziv et al., Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury PMCID: PMC1838759 Corrects: Yaniv Ziv, et al. Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc Natl Acad Sci U S A. 2006 August 29; 103(35): 13174–13179. |
