| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 October 24; 103(43): 15723–15724. doi: 10.1073/iti4306103.PMCID: PMC1635069 Commentaries Smoking and lung cancer—a new role for an old toxicant? Stephen S. Hecht PMCID: PMC1635070 Predicting complex biology with simple chemistry Irving R. Epstein PMCID: PMC1635071 Perspective Powering the planet: Chemical challenges in solar energy utilization Nathan S. Lewis and Daniel G. Nocera PMCID: PMC1635072 Profile Profile of Jacob N. Israelachvili Nick Zagorski PMCID: PMC1636843 Physical Sciences Chemistry From the Cover:
Modular chemical mechanism predicts spatiotemporal dynamics of initiation in the complex network of hemostasis Christian J. Kastrup, Matthew K. Runyon, Feng Shen, and Rustem F. Ismagilov PMCID: PMC1635074 Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase Lin Wang, Nina M. Goodey, Stephen J. Benkovic, and Amnon Kohen PMCID: PMC1635075 From the Cover:
Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution Christopher K. Haluska, Karin A. Riske, Valérie Marchi-Artzner, Jean-Marie Lehn, Reinhard Lipowsky, and Rumiana Dimova PMCID: PMC1613233 Geology Late Archean rise of aerobic microbial ecosystems Jennifer L. Eigenbrode and Katherine H. Freeman PMCID: PMC1635076 Physics From the Cover:
Branch-cut singularities in thermodynamics of Fermi liquid systems Arkady Shekhter and Alexander M. Finkel'stein PMCID: PMC1635077 Biological Sciences Applied Biological Sciences An algorithm for assembly of ordered restriction maps from single DNA molecules Anton Valouev, David C. Schwartz, Shiguo Zhou, and Michael S. Waterman PMCID: PMC1635078 Applied Mathematics An algorithm for assembly of ordered restriction maps from single DNA molecules Anton Valouev, David C. Schwartz, Shiguo Zhou, and Michael S. Waterman PMCID: PMC1635078 Biochemistry Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase Lin Wang, Nina M. Goodey, Stephen J. Benkovic, and Amnon Kohen PMCID: PMC1635075 Human DNA polymerase κ forms nonproductive complexes with matched primer termini but not with mismatched primer termini Karissa D. Carlson, Robert E. Johnson, Louise Prakash, Satya Prakash, and M. Todd Washington PMCID: PMC1635079 The genomic landscape of histone modifications in human T cells Tae-Young Roh, Suresh Cuddapah, Kairong Cui, and Keji Zhao PMCID: PMC1613230 The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II Hans Elmlund, Vera Baraznenok, Martin Lindahl, Camilla O. Samuelsen, Philip J. B. Koeck, Steen Holmberg, Hans Hebert, and Claes M. Gustafsson PMCID: PMC1635081 Vitamin K-dependent proteins in Ciona intestinalis, a basal chordate lacking a blood coagulation cascade John D. Kulman, Jeff E. Harris, Noriko Nakazawa, Michio Ogasawara, Masanobu Satake, and Earl W. Davie PMCID: PMC1635082 Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL Eli Chapman, George W. Farr, Renata Usaite, Krystyna Furtak, Wayne A. Fenton, Tapan K. Chaudhuri, Elise R. Hondorp, Rowena G. Matthews, Sharon G. Wolf, John R. Yates, Marc Pypaert, and Arthur L. Horwich PMCID: PMC1613232 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Recent progress in understanding hydrophobic interactions Emily E. Meyer, Kenneth J. Rosenberg, and Jacob Israelachvili PMCID: PMC1635073 Characterization of the nanoscale properties of individual amyloid fibrils Jeffrey F. Smith, Tuomas P. J. Knowles, Christopher M. Dobson, Cait E. MacPhee, and Mark E. Welland PMCID: PMC1635084 The distance that kinesin-1 holds its cargo from the microtubule surface measured by fluorescence interference contrast microscopy Jacob Kerssemakers, Jonathon Howard, Henry Hess, and Stefan Diez PMCID: PMC1595308 Cell-free formation of misfolded prion protein with authentic prion infectivity Petra Weber, Armin Giese, Niklas Piening, Gerda Mitteregger, Achim Thomzig, Michael Beekes, and Hans A. Kretzschmar PMCID: PMC1635086 Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Aβ42 peptide Woojin Kim and Michael H. Hecht PMCID: PMC1635087 Structural basis for mRNA and tRNA positioning on the ribosome Veysel Berk, Wen Zhang, Raj D. Pai, and Jamie H. D. Cate PMCID: PMC1635088 Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination Masoud Vedadi, Frank H. Niesen, Abdellah Allali-Hassani, Oleg Y. Fedorov, Patrick J. Finerty, Jr., Gregory A. Wasney, Ron Yeung, Cheryl Arrowsmith, Linda J. Ball, Helena Berglund, Raymond Hui, Brian D. Marsden, Pär Nordlund, Michael Sundstrom, Johan Weigelt, and Aled M. Edwards PMCID: PMC1595307 From the Cover:
Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution Christopher K. Haluska, Karin A. Riske, Valérie Marchi-Artzner, Jean-Marie Lehn, Reinhard Lipowsky, and Rumiana Dimova PMCID: PMC1613233 Unusual mechanical stability of a minimal RNA kissing complex Pan T. X. Li, Carlos Bustamante, and Ignacio Tinoco, Jr. PMCID: PMC1635091 Pressure-driven transport of confined DNA polymers in fluidic channels Derek Stein, Frank H. J. van der Heyden, Wiepke J. A. Koopmans, and Cees Dekker PMCID: PMC1635092 Sampling the multiple folding mechanisms of Trp-cage in explicit solvent J. Juraszek and P. G. Bolhuis PMCID: PMC1595309 Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer Jessica Richardson, Rikard Blunck, Pinghua Ge, Paul R. Selvin, Francisco Bezanilla, Diane M. Papazian, and Ana M. Correa PMCID: PMC1635094 Effect of force on mononucleosomal dynamics Shirley Mihardja, Andrew J. Spakowitz, Yongli Zhang, and Carlos Bustamante PMCID: PMC1635095 Cell Biology From the Cover:
UV irradiation induces a postreplication DNA damage checkpoint A. John Callegari and Thomas J. Kelly PMCID: PMC1613229 An intramolecular folding sensor for imaging estrogen receptor–ligand interactions Ramasamy Paulmurugan and Sanjiv S. Gambhir PMCID: PMC1635097 erbB2 is required for G protein-coupled receptor signaling in the heart Alejandra Negro, Bhawanjit K. Brar, Yusu Gu, Kirk L. Peterson, Wylie Vale, and Kuo-Fen Lee PMCID: PMC1635098 Developmental Biology Tdrd1/Mtr-1, a tudor-related gene, is essential for male germ-cell differentiation and nuage/germinal granule formation in mice Shinichiro Chuma, Mihoko Hosokawa, Kouichi Kitamura, Shinya Kasai, Makio Fujioka, Masateru Hiyoshi, Kazufumi Takamune, Toshiaki Noce, and Norio Nakatsuji PMCID: PMC1635099 Diversin regulates heart formation and gastrulation movements in development Heinz Moeller, Andreas Jenny, Hans-Joerg Schaeffer, Thomas Schwarz-Romond, Marek Mlodzik, Matthias Hammerschmidt, and Walter Birchmeier PMCID: PMC1635100 Ecology A tunable algorithm for collective decision-making Stephen C. Pratt and David J. T. Sumpter PMCID: PMC1635101 Evolution Natural variation in Drosophila melanogaster diapause due to the insulin-regulated PI3-kinase Karen D. Williams, Macarena Busto, Maximiliano L. Suster, Anthony K.-C. So, Yehuda Ben-Shahar, Sally J. Leevers, and Marla B. Sokolowski PMCID: PMC1635102 Microsporidian mitosomes retain elements of the general mitochondrial targeting system Lena Burri, Bryony A. P. Williams, Dejan Bursac, Trevor Lithgow, and Patrick J. Keeling PMCID: PMC1635103 From the Cover:
Hereditary family signature of facial expression Gili Peleg, Gadi Katzir, Ofer Peleg, Michal Kamara, Leonid Brodsky, Hagit Hel-Or, Daniel Keren, and Eviatar Nevo PMCID: PMC1635104 Genetics Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia Marjorie J. Lindhurst, Giuseppe Fiermonte, Shiwei Song, Eduard Struys, Francesco De Leonardis, Pamela L. Schwartzberg, Amy Chen, Alessandra Castegna, Nanda Verhoeven, Christopher K. Mathews, Ferdinando Palmieri, and Leslie G. Biesecker PMCID: PMC1595310 Isolation, characterization, and genetic complementation of a cellular mutant resistant to retroviral infection Sumit Agarwal, Josephine Harada, Jeffrey Schreifels, Patrycja Lech, Bryan Nikolai, Tomoyuki Yamaguchi, Sumit K. Chanda, and Nikunj V. Somia PMCID: PMC1636844 Differential sensitivities of transcription factor target genes underlie cell type-specific gene expression profiles Kirby D. Johnson, Shin-Il Kim, and Emery H. Bresnick PMCID: PMC1635106 Immunology Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification Katerina Artavanis-Tsakonas, J. Christopher Love, Hidde L. Ploegh, and Jatin M. Vyas PMCID: PMC1635107 Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2−/−γc−/− mice Stefan Baenziger, Roxane Tussiwand, Erika Schlaepfer, Luca Mazzucchelli, Mathias Heikenwalder, Michael O. Kurrer, Silvia Behnke, Joachim Frey, Annette Oxenius, Helen Joller, Adriano Aguzzi, Markus G. Manz, and Roberto F. Speck PMCID: PMC1635108 GATA factors participate in tissue-specific immune responses in Drosophila larvae Kate Senger, Kristina Harris, and Mike Levine PMCID: PMC1635109 Differences in potential for amino acid change after mutation reveals distinct strategies for κ and λ light-chain variation Uri Hershberg and Mark J. Shlomchik PMCID: PMC1635110 Medical Sciences Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1 Shaoyong Chen, Youyuan Xu, Xin Yuan, Glenn J. Bubley, and Steven P. Balk PMCID: PMC1635111 Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy Victor L. J. L. Thijssen, Ruben Postel, Ricardo J. M. G. E. Brandwijk, Ruud P. M. Dings, Irina Nesmelova, Sietske Satijn, Nicole Verhofstad, Yusaku Nakabeppu, Linda G. Baum, Jeroen Bakkers, Kevin H. Mayo, Françoise Poirier, and Arjan W. Griffioen PMCID: PMC1635112 An inherent role of microtubule network in the action of nuclear receptor Bramanandam Manavathi, Filippo Acconcia, Suresh K. Rayala, and Rakesh Kumar PMCID: PMC1635113 Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination Wing-pui Kong, Chantelle Hood, Zhi-yong Yang, Chih-Jen Wei, Ling Xu, Adolfo García-Sastre, Terrence M. Tumpey, and Gary J. Nabel PMCID: PMC1613227 Detection of inflamed atherosclerotic lesions with diadenosine-5′,5 ![[triple prime]](corehtml/pmc/pmcents/x2034.gif) - P1, P4-tetraphosphate (Ap 4A) and positron-emission tomography D. R. Elmaleh, A. J. Fischman, A. Tawakol, A. Zhu, T. M. Shoup, U. Hoffmann, A.-L. Brownell, and P. C. Zamecnik PMCID: PMC1599947 Ultrashort antibacterial and antifungal lipopeptides Arik Makovitzki, Dorit Avrahami, and Yechiel Shai PMCID: PMC1635116 PGC-1α controls hepatitis B virus through nutritional signals Amir Shlomai, Nir Paran, and Yosef Shaul PMCID: PMC1635117 Microbiology Emergence of a bacterial clone with enhanced virulence by acquisition of a phage encoding a secreted phospholipase A2 Izabela Sitkiewicz, Michal J. Nagiec, Paul Sumby, Stephanie D. Butler, Colette Cywes-Bentley, and James M. Musser PMCID: PMC1635118 Neuroscience Direct magnetic resonance detection of neuronal electrical activity Natalia Petridou, Dietmar Plenz, Afonso C. Silva, Murray Loew, Jerzy Bodurka, and Peter A. Bandettini PMCID: PMC1635119 Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis David R. Beers, Jenny S. Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A. Yen, Laszlo Siklos, Scott R. McKercher, and Stanley H. Appel PMCID: PMC1613228 A role for adrenomedullin as a pain-related peptide in the rat Weiya Ma, Jean-Guy Chabot, and Remi Quirion PMCID: PMC1635121 Neural correlates of epigenesis Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W. Haas, Zenab Amin, Martin J. Herrmann, R. Todd Constable, and Klaus Peter Lesch PMCID: PMC1592642 Physiology IL-1 resets glucose homeostasis at central levels Adriana del Rey, Eduardo Roggero, Anke Randolf, Carolina Mahuad, Samuel McCann, Valeria Rettori, and Hugo O. Besedovsky PMCID: PMC1635123 Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT1 and AT2 receptors Ming-Zhi Zhang, Bing Yao, Hui-Fang Cheng, Su-Wan Wang, Tadashi Inagami, and Raymond C. Harris PMCID: PMC1635124 Plant Biology Calcium regulation of chloroplast protein translocation is mediated by calmodulin binding to Tic32 Fatima Chigri, Friederike Hörmann, Anna Stamp, David K. Stammers, Bettina Bölter, Jürgen Soll, and Ute C. Vothknecht PMCID: PMC1635125 Social Sciences Psychology Neural correlates of epigenesis Turhan Canli, Maolin Qiu, Kazufumi Omura, Eliza Congdon, Brian W. Haas, Zenab Amin, Martin J. Herrmann, R. Todd Constable, and Klaus Peter Lesch PMCID: PMC1592642 Corrections Correction for Goldberg et al., A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes PMCID: PMC1635126 Corrects: Susanne M. D. Goldberg, et al. A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes. Proc Natl Acad Sci U S A. 2006 July 25; 103(30): 11240–11245. Correction for Simonin et al., RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia PMCID: PMC1635127 Corrects: Frédéric Simonin, et al. RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci U S A. 2006 January 10; 103(2): 466–471. Correction for Kozlov et al., Target cell-specific modulation of neuronal activity by astrocytes PMCID: PMC1635128 Corrects: A. S. Kozlov, et al. Target cell-specific modulation of neuronal activity by astrocytes. Proc Natl Acad Sci U S A. 2006 June 27; 103(26): 10058–10063. |
