| | This journal provides immediate access to some articles. Commentaries TorsinA and torsion dystonia: Unraveling the architecture of the nuclear envelope Larry Gerace PMCID: PMC428431 S-nitrosylation: Physiological regulation of NF-κB Harvey E. Marshall, Douglas T. Hess, and Jonathan S. Stamler PMCID: PMC428432 Myc degradation: Dancing with ubiquitin ligases Bruno Amati PMCID: PMC428433 Physical Sciences Chemistry Three-dimensional phase-encoded chemical shift MRI in the presence of inhomogeneous fields Vasiliki Demas, Dimitris Sakellariou, Carlos A. Meriles, Songi Han, Jeffrey Reimer, and Alexander Pines PMCID: PMC428434 Geophysics Preferential states in soil moisture and climate dynamics Paolo D'Odorico and Amilcare Porporato PMCID: PMC428435 Biological Sciences Applied Biological Sciences Development of insulin resistance and obesity in mice overexpressing cellular glutathione peroxidase James P. McClung, Carol A. Roneker, Weipeng Mu, Donald J. Lisk, Paul Langlais, Feng Liu, and Xin Gen Lei PMCID: PMC428436 Biochemistry Kinetic isotope effects in Ras-catalyzed GTP hydrolysis: Evidence for a loose transition state Xinlin Du, Gavin E. Black, Paolo Lecchi, Fred P. Abramson, and Stephen R. Sprang PMCID: PMC428437 Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21 Yuxin Yin, Aiping Zhu, Yan J. Jin, Yu-Xin Liu, Xia Zhang, Kevin M. Hopkins, and Howard B. Lieberman PMCID: PMC428438 Modification of the erythroid transcription factor GATA-1 by SUMO-1 Licio Collavin, Monica Gostissa, Fabio Avolio, Paola Secco, Antonella Ronchi, Claudio Santoro, and Giannino Del Sal PMCID: PMC428439 Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide Begoña Heras, Melissa A. Edeling, Horst J. Schirra, Satish Raina, and Jennifer L. Martin PMCID: PMC428440 Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells Zhiwen Zhang, Lital Alfonta, Feng Tian, Badry Bursulaya, Sean Uryu, David S. King, and Peter G. Schultz PMCID: PMC428441 Phosphoprotein inhibitor CPI-17 specificity depends on allosteric regulation of protein phosphatase-1 by regulatory subunits Masumi Eto, Toshio Kitazawa, and David L. Brautigan PMCID: PMC428442 Hypoxic inducible factor 1α, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide Douglas D. Thomas, Michael Graham Espey, Lisa A. Ridnour, Lorne J. Hofseth, Daniele Mancardi, Curtis C. Harris, and David A. Wink PMCID: PMC428443 Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications Rajendra K. Agrawal, Manjuli R. Sharma, Michael C. Kiel, Go Hirokawa, Timothy M. Booth, Christian M. T. Spahn, Robert A. Grassucci, Akira Kaji, and Joachim Frank PMCID: PMC428444 Interplay between Drosophila Bloom's syndrome helicase and Ku autoantigen during nonhomologous end joining repair of P element-induced DNA breaks Bosun Min, Brian T. Weinert, and Donald C. Rio PMCID: PMC428445 Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand Patricia J. Willy, Ian R. Murray, Jing Qian, Brett B. Busch, William C. Stevens, Jr., Richard Martin, Raju Mohan, Sihong Zhou, Peter Ordentlich, Ping Wei, Douglas W. Sapp, Robert A. Horlick, Richard A. Heyman, and Ira G. Schulman PMCID: PMC428446 The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization Rosa M. Canet-Avilés, Mark A. Wilson, David W. Miller, Rili Ahmad, Chris McLendon, Sourav Bandyopadhyay, Melisa J. Baptista, Dagmar Ringe, Gregory A. Petsko, and Mark R. Cookson PMCID: PMC428480 Biophysics The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function Ty E. Adams, Matthew F. Hockin, Kenneth G. Mann, and Stephen J. Everse PMCID: PMC428447 Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation Vannakambadi K. Ganesh, Scott A. Smith, Girish J. Kotwal, and Krishna H. M. Murthy PMCID: PMC428448 Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding Dipesh Risal, S. Gourinath, Daniel M. Himmel, Andrew G. Szent-Györgyi, and Carolyn Cohen PMCID: PMC428449 Fluorescence-aided molecule sorting: Analysis of structure and interactions by alternating-laser excitation of single molecules Achillefs N. Kapanidis, Nam Ki Lee, Ted A. Laurence, Sören Doose, Emmanuel Margeat, and Shimon Weiss PMCID: PMC428450 Prediction of protein folding rates from the amino acid sequence-predicted secondary structure Dmitry N. Ivankov and Alexei V. Finkelstein PMCID: PMC428451 Cell Biology From the Cover:
Nitric oxide represses inhibitory κB kinase through S-nitrosylation Niki L. Reynaert, Karina Ckless, Solange H. Korn, Nanda Vos, Amy S. Guala, Emiel F. M. Wouters, Albert van der Vliet, and Yvonne M. W. Janssen-Heininger PMCID: PMC428452 Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton Chris Janetopoulos, Lan Ma, Peter N. Devreotes, and Pablo A. Iglesias PMCID: PMC428453 Inhibition of nuclear import and cell-cycle progression by mutated forms of the dynamin-like GTPase MxB Megan C. King, Graça Raposo, and Mark A. Lemmon PMCID: PMC428454 Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome Robert D. Goldman, Dale K. Shumaker, Michael R. Erdos, Maria Eriksson, Anne E. Goldman, Leslie B. Gordon, Yosef Gruenbaum, Satya Khuon, Melissa Mendez, Renée Varga, and Francis S. Collins PMCID: PMC428455 Chemical genetics to identify NFAT inhibitors: Potential of targeting calcium mobilization in immunosuppression Natarajan Venkatesh, Yan Feng, Brian DeDecker, Patrick Yacono, David Golan, Timothy Mitchison, and Frank McKeon PMCID: PMC428456 Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion Jian Du and Gregory J. Hannon PMCID: PMC428457 From the Cover:
Critical roles of interferon regulatory factor 4 in CD11bhighCD8α– dendritic cell development Shoichi Suzuki, Kiri Honma, Toshifumi Matsuyama, Kazuo Suzuki, Kan Toriyama, Ichinose Akitoyo, Kazuo Yamamoto, Takashi Suematsu, Michio Nakamura, Katsuyuki Yui, and Atsushi Kumatori PMCID: PMC428458 Developmental Biology Spatiotemporal retinoid-X receptor activation detected in live vertebrate embryos Ayala Luria and J. David Furlow PMCID: PMC428459 Ecology Biochemical crypsis in the avoidance of natural enemies by an insect herbivore Consuelo M. De Moraes and Mark C. Mescher PMCID: PMC428460 Genetic diversity enhances the resistance of a seagrass ecosystem to disturbance A. Randall Hughes and John J. Stachowicz PMCID: PMC428461 Evolution Caenorhabditis phylogeny predicts convergence of hermaphroditism and extensive intron loss Karin Kiontke, Nicholas P. Gavin, Yevgeniy Raynes, Casey Roehrig, Fabio Piano, and David H. A. Fitch PMCID: PMC428462 Early events in speciation: Polymorphism for hybrid male sterility in Drosophila Laura K. Reed and Therese A. Markow PMCID: PMC428463 Silencing of a gene adjacent to the breakpoint of a widespread Drosophila inversion by a transposon-induced antisense RNA Marta Puig, Mario Cáceres, and Alfredo Ruiz PMCID: PMC428464 From the Cover:
Selective pressures on the olfactory receptor repertoire since the human-chimpanzee divergence Alexander A. Gimelbrant, Helen Skaletsky, and Andrew Chess PMCID: PMC428465 Phylogenetic expression of Galα1-4Gal on avian glycoproteins: Glycan differentiation inscribed in the early history of modern birds Noriko Suzuki, Michael Laskowski,, Jr., and Yuan C. Lee PMCID: PMC428466 Plant-derived pyrrolizidine alkaloid protects eggs of a moth (Utetheisa ornatrix) against a parasitoid wasp (Trichogramma ostriniae) Alexander Bezzerides, Tze-Hei Yong, Julie Bezzerides, Jad Husseini, Joshua Ladau, Maria Eisner, and Thomas Eisner PMCID: PMC428467 Coevolution of gene expression among interacting proteins Hunter B. Fraser, Aaron E. Hirsh, Dennis P. Wall, and Michael B. Eisen PMCID: PMC439012 Genetics Mutator genes for suppression of gross chromosomal rearrangements identified by a genome-wide screening in Saccharomyces cerevisiae Stephanie Smith, Ji-Young Hwang, Soma Banerjee, Anju Majeed, Amitabha Gupta, and Kyungjaem Myung PMCID: PMC428469 Genetic control of branching in foxtail millet Andrew N. Doust, Katrien M. Devos, Michael D. Gadberry, Mike D. Gale, and Elizabeth A. Kellogg PMCID: PMC428470 Immunology Tumor-specific Ab-mediated targeting of MHC-peptide complexes induces regression of human tumor xenografts in vivo Avital Lev, Roy Noy, Kfir Oved, Hila Novak, Dina Segal, Peter Walden, Dietmar Zehn, and Yoram Reiter PMCID: PMC428471 Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox Geeta Chaudhri, Vijay Panchanathan, R. Mark L. Buller, Alfons J. M. van den Eertwegh, Eric Claassen, Jie Zhou, Rosalind de Chazal, Jon D. Laman, and Gunasegaran Karupiah PMCID: PMC428472 T cell receptor-ligand interactions: A conformational preequilibrium or an induced fit Dmitry M. Gakamsky, Immanuel F. Luescher, and Israel Pecht PMCID: PMC428473 Medical Sciences High-resolution characterization of the pancreatic adenocarcinoma genome Andrew J. Aguirre, Cameron Brennan, Gerald Bailey, Raktim Sinha, Bin Feng, Christopher Leo, Yunyu Zhang, Jean Zhang, Joseph D. Gans, Nabeel Bardeesy, Craig Cauwels, Carlos Cordon-Cardo, Mark S. Redston, Ronald A. DePinho, and Lynda Chin PMCID: PMC428474 Effective inhibition of Rta expression and lytic replication of Kaposi's sarcoma-associated herpesvirus by human RNase P Jiaming Zhu, Phong Trang, Kihoon Kim, Tianhong Zhou, Hongyu Deng, and Fenyong Liu PMCID: PMC428475 Activation of NF-κB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis Archontoula Stoffel, Mira Chaurushiya, Bhuvanesh Singh, and Arnold J. Levine PMCID: PMC428476 From the Cover:
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation Markus Welcker, Amir Orian, Jianping Jin, Jonathan A. Grim, J. Wade Harper, Robert N. Eisenman, and Bruce E. Clurman PMCID: PMC428477 Microbiology Genome sequence of Picrophilus torridus and its implications for life around pH 0 O. Fütterer, A. Angelov, H. Liesegang, G. Gottschalk, C. Schleper, B. Schepers, C. Dock, G. Antranikian, and W. Liebl PMCID: PMC428478 Neuroscience Functional organization of sensory input to the olfactory bulb glomerulus analyzed by two-photon calcium imaging Matt Wachowiak, Winfried Denk, and Rainer W. Friedrich PMCID: PMC428479 The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization Rosa M. Canet-Avilés, Mark A. Wilson, David W. Miller, Rili Ahmad, Chris McLendon, Sourav Bandyopadhyay, Melisa J. Baptista, Dagmar Ringe, Gregory A. Petsko, and Mark R. Cookson PMCID: PMC428480 Knock-in human rhodopsin-GFP fusions as mouse models for human disease and targets for gene therapy Fung Chan, Allan Bradley, Theodore G. Wensel, and John H. Wilson PMCID: PMC428481 Pharmacology A neurokinin 1 receptor antagonist decreases postoperative peritoneal adhesion formation and increases peritoneal fibrinolytic activity Karen L. Reed, A. Brent Fruin, Adam C. Gower, Arthur F. Stucchi, Susan E. Leeman, and James M. Becker PMCID: PMC428482 RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: A mechanism for diabetes-associated erectile dysfunction Trinity J. Bivalacqua, Hunter C. Champion, Mustafa F. Usta, Selim Cellek, Kanchan Chitaley, R. Clinton Webb, Ronald L. Lewis, Thomas M. Mills, Wayne J. G. Hellstrom, and Philip J. Kadowitz PMCID: PMC428483 Identification of the xenosensors regulating human 5-aminolevulinate synthase Michael Podvinec, Christoph Handschin, Renate Looser, and Urs A. Meyer PMCID: PMC428484 Physiology Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans Todd G. Nystul and Mark B. Roth PMCID: PMC428485 A cardiac arrhythmia syndrome caused by loss of ankyrin-B function Peter J. Mohler, Igor Splawski, Carlo Napolitano, Georgia Bottelli, Leah Sharpe, Katherine Timothy, Silvia G. Priori, Mark T. Keating, and Vann Bennett PMCID: PMC428486 Plant Biology AtNAP7 is a plastidic SufC-like ATP-binding cassette/ATPase essential for Arabidopsis embryogenesis Xiang Ming Xu and Simon Geir Møller PMCID: PMC428487 Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis Stefan Jennewein, Mark R. Wildung, MyDoanh Chau, Kevin Walker, and Rodney Croteau PMCID: PMC428488 Population Biology Using conservation of pattern to estimate spatial parameters from a single snapshot Matt J. Keeling, Stephen P. Brooks, and Christopher A. Gilligan PMCID: PMC428489 Age-structured red blood cell susceptibility and the dynamics of malaria infections Philip G. McQueen and F. Ellis McKenzie PMCID: PMC428490 From the Cover:
Origins and dispersals of Pacific peoples: Evidence from mtDNA phylogenies of the Pacific rat E. Matisoo-Smith and J. H. Robins PMCID: PMC428491 Social Sciences Anthropology From the Cover:
Origins and dispersals of Pacific peoples: Evidence from mtDNA phylogenies of the Pacific rat E. Matisoo-Smith and J. H. Robins PMCID: PMC428491 |
