| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 11957–11958. doi: 10.1073/iti3405102.PMCID: PMC1189356 Commentaries Genomes on the shrink Howard Ochman PMCID: PMC1189353 Green light for gene targeting in plants Holger Puchta and Barbara Hohn PMCID: PMC1189331 Physical Sciences Applied Physical Sciences Microoxen: Microorganisms to move microscale loads Douglas B. Weibel, Piotr Garstecki, Declan Ryan, Willow R. DiLuzio, Michael Mayer, Jennifer E. Seto, and George M. Whitesides PMCID: PMC1189341 Coupled biophysical global ocean model and molecular genetic analyses identify multiple introductions of cryptogenic species Michael N Dawson, Alex Sen Gupta, and Matthew H. England PMCID: PMC1189321 Engineering The electroosmotic droplet switch: Countering capillarity with electrokinetics Michael J. Vogel, Peter Ehrhard, and Paul H. Steen PMCID: PMC1189335 Geology Decoupled taxonomic radiation and ecological expansion of open-habitat grasses in the Cenozoic of North America Caroline A. E. Strömberg PMCID: PMC1189350 Physics Bohr's 1913 molecular model revisited Anatoly A. Svidzinsky, Marlan O. Scully, and Dudley R. Herschbach PMCID: PMC1186029 Observation of the skin-depth effect on the Casimir force between metallic surfaces Mariangela Lisanti, Davide Iannuzzi, and Federico Capasso PMCID: PMC1189346 Biological Sciences Applied Biological Sciences Coupled biophysical global ocean model and molecular genetic analyses identify multiple introductions of cryptogenic species Michael N Dawson, Alex Sen Gupta, and Matthew H. England PMCID: PMC1189321 From the Cover:
Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide Srinivas Rao, Stella Hu, Louise McHugh, Kira Lueders, Ken Henry, Qi Zhao, Richard A. Fekete, Sudeshna Kar, Sankar Adhya, and Dean H. Hamer PMCID: PMC1189328 Amelioration of laminin-α2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin Chunping Qiao, Jianbin Li, Tong Zhu, Romesh Draviam, Simon Watkins, Xiaojing Ye, Chunlian Chen, Juan Li, and Xiao Xiao PMCID: PMC1189311 Biochemistry Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia Anna C. Schinzel, Osamu Takeuchi, Zhihong Huang, Jill K. Fisher, Zhipeng Zhou, Jeffery Rubens, Claudio Hetz, Nika N. Danial, Michael A. Moskowitz, and Stanley J. Korsmeyer PMCID: PMC1189333 Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal Lutfi Abu-Elheiga, Martin M. Matzuk, Parichher Kordari, WonKeun Oh, Tattym Shaikenov, Ziwei Gu, and Salih J. Wakil PMCID: PMC1189351 Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action David Baram, Erez Pyetan, Assa Sittner, Tamar Auerbach-Nevo, Anat Bashan, and Ada Yonath PMCID: PMC1183488 Targets of microRNA regulation in the Drosophila oocyte proteome Kenji Nakahara, Kevin Kim, Christin Sciulli, Susan R. Dowd, Jonathan S. Minden, and Richard W. Carthew PMCID: PMC1189302 Methanococcus vannielii selenium-binding protein (SeBP): Chemical reactivity of recombinant SeBP produced in Escherichia coli Kemberly G. Patteson, Neel Trivedi, and Thressa C. Stadtman PMCID: PMC1189349 Biophysics Sequence optimization and designability of enzyme active sites Raj Chakrabarti, Alexander M. Klibanov, and Richard A. Friesner PMCID: PMC1189337 Atomic resolution structures of resting-state, substrate- and product-complexed Cu-nitrite reductase provide insight into catalytic mechanism Svetlana V. Antonyuk, Richard W. Strange, Gary Sawers, Robert R. Eady, and S. Samar Hasnain PMCID: PMC1189323 From the Cover:
X-ray damage to the Mn4Ca complex in single crystals of photosystem II: A case study for metalloprotein crystallography Junko Yano, Jan Kern, Klaus-Dieter Irrgang, Matthew J. Latimer, Uwe Bergmann, Pieter Glatzel, Yulia Pushkar, Jacek Biesiadka, Bernhard Loll, Kenneth Sauer, Johannes Messinger, Athina Zouni, and Vittal K. Yachandra PMCID: PMC1186027 Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2 Mai Marie Holm, Marie-Louise Lunn, Stephen F. Traynelis, Jette S. Kastrup, and Jan Egebjerg PMCID: PMC1189343 Monte Carlo modeling of single-molecule cytoplasmic dynein Manoranjan P. Singh, Roop Mallik, Steven P. Gross, and Clare C. Yu PMCID: PMC1189307 Cell Biology Neuronal ELAV proteins enhance mRNA stability by a PKCα-dependent pathway Alessia Pascale, Marialaura Amadio, Giovanni Scapagnini, Cristina Lanni, Marco Racchi, Alessandro Provenzani, Stefano Govoni, Daniel L. Alkon, and Alessandro Quattrone PMCID: PMC1189326 Brain and muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock, regulates adipogenesis Shigeki Shimba, Norimasa Ishii, Yuki Ohta, Toshiharu Ohno, Yuichi Watabe, Mitsuaki Hayashi, Taira Wada, Toshinori Aoyagi, and Masakatsu Tezuka PMCID: PMC1189312 Synergistic induction of tissue factor by coagulation factor Xa and TNF: Evidence for involvement of negative regulatory signaling cascades Ayala Hezi-Yamit, Paul W. Wong, Nga Bien-Ly, Laszlo G. Komuves, K. S. Srinivasa Prasad, David R. Phillips, and Uma Sinha PMCID: PMC1189324 Differential patterns of apoptosis in response to aging in Drosophila Jie Zheng, Scott W. Edelman, Grace Tharmarajah, David W. Walker, Scott D. Pletcher, and Laurent Seroude PMCID: PMC1189317 Identification of an interactor of cadmium ion-induced glycine-rich protein involved in regulation of callose levels in plant vasculature Shoko Ueki and Vitaly Citovsky PMCID: PMC1189354 A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid Shailaja Kasibhatla, Katayoun A. Jessen, Sergei Maliartchouk, Jean Yu Wang, Nicole M. English, John Drewe, Ling Qiu, Shannon P. Archer, Anthony E. Ponce, Nilantha Sirisoma, Songchun Jiang, Han-Zhong Zhang, Kurt R. Gehlsen, Sui Xiong Cai, Douglas R. Green, and Ben Tseng PMCID: PMC1189297 Developmental Biology HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells Sandra Pilat, Sebastian Carotta, Bernhard Schiedlmeier, Kenji Kamino, Andreas Mairhofer, Elke Will, Ute Modlich, Peter Steinlein, Wolfram Ostertag, Christopher Baum, Hartmut Beug, and Hannes Klump PMCID: PMC1189347 Evolution Unifying the spatial population dynamics and molecular evolution of epidemic rabies virus Leslie A. Real, J. Caroline Henderson, Roman Biek, Jennifer Snaman, Tracy Lambert Jack, James E. Childs, Eli Stahl, Lance Waller, Rowland Tinline, and Susan Nadin-Davis PMCID: PMC1186024 Genetics From the Cover:
Bacterial genome size reduction by experimental evolution A. I. Nilsson, S. Koskiniemi, S. Eriksson, E. Kugelberg, J. C. D. Hinton, and D. I. Andersson PMCID: PMC1189319 In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation Giovanni Perini, Daniel Diolaiti, Antonio Porro, and Giuliano Della Valle PMCID: PMC1184034 Large-scale identification of yeast integral membrane protein interactions John P. Miller, Russell S. Lo, Asa Ben-Hur, Cynthia Desmarais, Igor Stagljar, William Stafford Noble, and Stanley Fields PMCID: PMC1189342 Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss Mary Tsikitis, Zhikai Zhang, Winfried Edelman, David Zagzag, and Ganjam V. Kalpana PMCID: PMC1189334 Characterization of Dicer-deficient murine embryonic stem cells Elizabeth P. Murchison, Janet F. Partridge, Oliver H. Tam, Sihem Cheloufi, and Gregory J. Hannon PMCID: PMC1185572 Arrestin-related proteins mediate pH signaling in fungi Silvia Herranz, José M. Rodríguez, Henk-Jan Bussink, Juan C. Sánchez-Ferrero, Herbert N. Arst, Jr., Miguel A. Peñalva, and Olivier Vincent PMCID: PMC1189327 Loss and gain of chromosome 5 controls growth of Candida albicans on sorbose due to dispersed redundant negative regulators M. Anaul Kabir, Ausaf Ahmad, Jay R. Greenberg, Ying-Kai Wang, and Elena Rustchenko PMCID: PMC1189348 Immunology α1-Antitrypsin monotherapy prolongs islet allograft survival in mice Eli C. Lewis, Leland Shapiro, Owen J. Bowers, and Charles A. Dinarello PMCID: PMC1189344 Medical Sciences An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation Zhiqiang Chen, Matthew W. Foster, Jian Zhang, Lan Mao, Howard A. Rockman, Toshihiro Kawamoto, Kyoko Kitagawa, Keiichi I. Nakayama, Douglas T. Hess, and Jonathan S. Stamler PMCID: PMC1189320 Preventing local regeneration of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 enhances angiogenesis Gary R. Small, Patrick W. F. Hadoke, Isam Sharif, Anna R. Dover, Danielle Armour, Christopher J. Kenyon, Gillian A. Gray, and Brian R. Walker PMCID: PMC1189304 Specific inhibition of CBP/β-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation Jia-Ling Teo, Hong Ma, Cu Nguyen, Crystal Lam, and Michael Kahn PMCID: PMC1189325 Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo Fumitaka Takeshita, Yoshiko Minakuchi, Shunji Nagahara, Kimi Honma, Hideo Sasaki, Kotaro Hirai, Takumi Teratani, Nachi Namatame, Yusuke Yamamoto, Koji Hanai, Takashi Kato, Akihiko Sano, and Takahiro Ochiya PMCID: PMC1183487 Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease Suneil Malik, Laurent Abel, Heather Tooker, Audrey Poon, Leah Simkin, Manon Girard, Gerald J. Adams, Jeffrey R. Starke, Kimberly C. Smith, Edward A. Graviss, James M. Musser, and Erwin Schurr PMCID: PMC1189316 From the Cover:
Roles of PSF protein and VL30 RNA in reversible gene regulation Xu Song, Ying Sun, and Alan Garen PMCID: PMC1189330 Microbiology Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells Melissa R. van Dijk, Bruno Douradinha, Blandine Franke-Fayard, Volker Heussler, Maaike W. van Dooren, Ben van Schaijk, Geert-Jan van Gemert, Robert W. Sauerwein, Maria M. Mota, Andrew P. Waters, and Chris J. Janse PMCID: PMC1189305 Ancestral antibiotic resistance in Mycobacterium tuberculosis Rowan P. Morris, Liem Nguyen, John Gatfield, Kevin Visconti, Kien Nguyen, Dirk Schnappinger, Sabine Ehrt, Yang Liu, Leonid Heifets, Jean Pieters, Gary Schoolnik, and Charles J. Thompson PMCID: PMC1186028 Coevolution between nonhomologous but functionally similar proteins and their conserved partners in the Legionella pathogenesis system Michal Feldman, Tal Zusman, Shelly Hagag, and Gil Segal PMCID: PMC1189309 Neuroscience Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention David S. Tuch, David H. Salat, Jonathan J. Wisco, Alexandra K. Zaleta, Nathanael D. Hevelone, and H. Diana Rosas PMCID: PMC1189298 Unraveling a role for dopamine in Huntington's disease: The dual role of reactive oxygen species and D2 receptor stimulation Delphine Charvin, Peter Vanhoutte, Christiane Pagès, Emiliana Borelli, and Jocelyne Caboche PMCID: PMC1189314 Beyond affect: A role for genetic variation of the serotonin transporter in neural activation during a cognitive attention task Turhan Canli, Kazufumi Omura, Brian W. Haas, Andreas Fallgatter, R. Todd Constable, and Klaus Peter Lesch PMCID: PMC1189322 Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death Kyung-Min Noh, Hidenori Yokota, Toshihiro Mashiko, Pablo E. Castillo, R. Suzanne Zukin, and Michael V. L. Bennett PMCID: PMC1189338 Higher-order thalamic relays burst more than first-order relays E. J. Ramcharan, J. W. Gnadt, and S. M. Sherman PMCID: PMC1189315 Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma Wei Huang, John B. Fileta, Adam Dobberfuhl, Theodoros Filippopolous, Yan Guo, Gina Kwon, and Cynthia L. Grosskreutz PMCID: PMC1186026 Pharmacology Pungent products from garlic activate the sensory ion channel TRPA1 Diana M. Bautista, Pouya Movahed, Andrew Hinman, Helena E. Axelsson, Olov Sterner, Edward D. Högestätt, David Julius, Sven-Eric Jordt, and Peter M. Zygmunt PMCID: PMC1189336 Physiology Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: Role in apical retention and targeting R. Todd Alexander, Wendy Furuya, Katalin Szászi, John Orlowski, and Sergio Grinstein PMCID: PMC1189301 Ca2+ sparks and secretion in dorsal root ganglion neurons Kunfu Ouyang, Hui Zheng, Xiaomei Qin, Chen Zhang, Dongmei Yang, Xian Wang, Caihong Wu, Zhuan Zhou, and Heping Cheng PMCID: PMC1189299 Plant Biology High-frequency gene targeting in Arabidopsis plants expressing the yeast RAD54 gene Hezi Shaked, Cathy Melamed-Bessudo, and Avraham A. Levy PMCID: PMC1189313 From the Cover:
A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening Jian Mao, Yan-Chun Zhang, Yi Sang, Qing-Hua Li, and Hong-Quan Yang PMCID: PMC1189306 Endocytosis and degradation of BOR1, a boron transporter of Arabidopsis thaliana, regulated by boron availability Junpei Takano, Kyoko Miwa, Lixing Yuan, Nicolaus von Wirén, and Toru Fujiwara PMCID: PMC1189310 Quality assessment of maize assembled genomic islands (MAGIs) and large-scale experimental verification of predicted genes Yan Fu, Scott J. Emrich, Ling Guo, Tsui-Jung Wen, Daniel A. Ashlock, Srinivas Aluru, and Patrick S. Schnable PMCID: PMC1186025 Corrections Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 12288. doi: 10.1073/pnas.0506076102.PMCID: PMC1189294 Corrects: Rina Aharoni, et al. Glatiramer acetate-specific T cells in the brain express T helper 2/3 cytokines and brain-derived neurotrophic factor in situ. Proc Natl Acad Sci U S A. 2003 November 25; 100(24): 14157–14162. Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 12288. doi: 10.1073/pnas.0506076102.PMCID: PMC1189295 Corrects: Hava Ben-David, et al. Down-regulation of myasthenogenic T cell responses by a dual altered peptide ligand via CD4+CD25+-regulated events leading to apoptosis. Proc Natl Acad Sci U S A. 2005 February 8; 102(6): 2028–2033. Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 12288. doi: 10.1073/pnas.0506076102.PMCID: PMC1189296 Corrects: Badiga Venkata Aruna, et al. Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells. Proc Natl Acad Sci U S A. 2005 July 19; 102(29): 10285–10290. Proc Natl Acad Sci U S A. 2005 August 23; 102(34): 12288. doi: 10.1073/pnas.0506076102.PMCID: PMC1189355 Corrects: Miri Paas-Rozner, et al. A dual altered peptide ligand down-regulates myasthenogenic T cell responses by up-regulating CD25- and CTLA-4-expressing CD4+ T cells. Proc Natl Acad Sci U S A. 2003 May 27; 100(11): 6676–6681. |
