| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 May 17; 102(20): 7051–7052. doi: 10.1073/iti2005102.PMCID: PMC1129151 Commentaries Evidence for an inflammatory process in age-related macular degeneration gains new support Dean Bok PMCID: PMC1129150 The success of animal invaders M. Jake Vander Zanden PMCID: PMC1129137 Physical Sciences Applied Mathematics A network analysis of committees in the U.S. House of Representatives Mason A. Porter, Peter J. Mucha, M. E. J. Newman, and Casey M. Warmbrand PMCID: PMC1129104 Applied Physical Sciences The use of oscillatory signals in the study of genetic networks Ovidiu Lipan and Wing H. Wong PMCID: PMC1129090 Chemistry Four-dimensional ultrafast electron microscopy Vladimir A. Lobastov, Ramesh Srinivasan, and Ahmed H. Zewail PMCID: PMC1129142 Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella Eric W. Schmidt, James T. Nelson, David A. Rasko, Sebastian Sudek, Jonathan A. Eisen, Margo G. Haygood, and Jacques Ravel PMCID: PMC1091749 Engineering From the Cover:
Controlled fabrication of hierarchically branched nanopores, nanotubes, and nanowires Guowen Meng, Yung Joon Jung, Anyuan Cao, Robert Vajtai, and Pulickel M. Ajayan PMCID: PMC1129116 Statistics De novo cis-regulatory module elicitation for eukaryotic genomes Mayetri Gupta and Jun S. Liu PMCID: PMC1129096 Biological Sciences Anthropology A late Neandertal femur from Les Rochers-de-Villeneuve, France Cédric Beauval, Bruno Maureille, François Lacrampe-Cuyaubère, David Serre, David Peressinotto, Jean-Guillaume Bordes, David Cochard, Isabelle Couchoud, David Dubrasquet, Véronique Laroulandie, Arnaud Lenoble, Jean-Baptiste Mallye, Sylvain Pasty, Jérôme Primault, Nadin Rohland, Svante Pääbo, and Erik Trinkaus PMCID: PMC1129143 Biochemistry Isolation and characterization of a retinal pigment epithelial cell fluorophore: An all-trans-retinal dimer conjugate Nathan E. Fishkin, Janet R. Sparrow, Rando Allikmets, and Koji Nakanishi PMCID: PMC1129110 Identification and analysis of vnd/NK-2 homeodomain binding sites in genomic DNA Lan-Hsiang Wang, Rebecca Chmelik, Derek Tang, and Marshall Nirenberg PMCID: PMC1129122 Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopy Xuekui Yu, Phong Trang, Sanket Shah, Ivo Atanasov, Yong-Hwan Kim, Yong Bai, Z. Hong Zhou, and Fenyong Liu PMCID: PMC1091747 Human biliverdin reductase: A member of the insulin receptor substrate family with serine/threonine/tyrosine kinase activity Nicole Lerner-Marmarosh, Jenny Shen, Michael D. Torno, Anatoliy Kravets, Zhenbo Hu, and Mahin D. Maines PMCID: PMC1088173 Structural properties of Aβ protofibrils stabilized by a small molecule Angela D. Williams, Matt Sega, Maolian Chen, Indu Kheterpal, Merav Geva, Valerie Berthelier, David T. Kaleta, Kelsey D. Cook, and Ronald Wetzel PMCID: PMC1091746 Studies of yeast oligosaccharyl transferase subunits using the split-ubiquitin system: Topological features and in vivo interactions Aixin Yan, Elain Wu, and William J. Lennarz PMCID: PMC1129144 Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease Yohei Kirino, Yu-ichi Goto, Yolanda Campos, Joaquin Arenas, and Tsutomu Suzuki PMCID: PMC1129107 Perinatal ω-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood Anura P. Jayasooriya, M. Leigh Ackland, Michael L. Mathai, Andrew J. Sinclair, Harrison S. Weisinger, Richard S. Weisinger, John E. Halver, Klára Kitajka, and László G. Puskás PMCID: PMC1129140 The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation Rajesh Ramachandran, Rodney K. Tweten, and Arthur E. Johnson PMCID: PMC1129106 From the Cover:
Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds Hyotcherl Ihee, Sudarshan Rajagopal, Vukica Šrajer, Reinhard Pahl, Spencer Anderson, Marius Schmidt, Friedrich Schotte, Philip A. Anfinrud, Michael Wulff, and Keith Moffat PMCID: PMC1088170 Biophysics Four-dimensional ultrafast electron microscopy Vladimir A. Lobastov, Ramesh Srinivasan, and Ahmed H. Zewail PMCID: PMC1129142 Detecting remotely related proteins by their interactions and sequence similarity Jordi Espadaler, Ramón Aragüés, Narayanan Eswar, Marc A. Marti-Renom, Enrique Querol, Francesc X. Avilés, Andrej Sali, and Baldomero Oliva PMCID: PMC1129109 How sequence defines structure: A crystallographic map of DNA structure and conformation Franklin A. Hays, Amy Teegarden, Zebulon J. R. Jones, Michael Harms, Dustin Raup, Jeffrey Watson, Emily Cavaliere, and P. Shing Ho PMCID: PMC1129101 Structural and functional similarities between the capsid proteins of bacteriophages T4 and HK97 point to a common ancestry Andrei Fokine, Petr G. Leiman, Mikhail M. Shneider, Bijan Ahvazi, Karen M. Boeshans, Alasdair C. Steven, Lindsay W. Black, Vadim V. Mesyanzhinov, and Michael G. Rossmann PMCID: PMC1129118 Investigating local conformations of double-stranded DNA by low-energy circular dichroism of pyrrolo-cytosine Neil P. Johnson, Walter A. Baase, and Peter H. von Hippel PMCID: PMC1129127 Cell Biology Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype Diana Vradii, Sayyed K. Zaidi, Jane B. Lian, Andre J. van Wijnen, Janet L. Stein, and Gary S. Stein PMCID: PMC1129117 Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue Patricia E. Burger, Xiaozhong Xiong, Sandra Coetzee, Sarah N. Salm, David Moscatelli, Ken Goto, and E. Lynette Wilson PMCID: PMC1129148 Balance of actively generated contractile and resistive forces controls cytokinesis dynamics Wendy Zhang and Douglas N. Robinson PMCID: PMC1129136 Developmental Biology Late-emigrating neural crest cells in the roof plate are restricted to a sensory fate by GDF7 Liching Lo, Emma L. Dormand, and David J. Anderson PMCID: PMC1091754 Ecology From the Cover:
Invasion success of vertebrates in Europe and North America Jonathan M. Jeschke and David L. Strayer PMCID: PMC1129111 Evolution Conservation and evolvability in regulatory networks: The evolution of ribosomal regulation in yeast Amos Tanay, Aviv Regev, and Ron Shamir PMCID: PMC1091753 Clathrin heavy and light chain isoforms originated by independent mechanisms of gene duplication during chordate evolution Diane E. Wakeham, Laurent Abi-Rached, Mhairi C. Towler, Jeremy D. Wilbur, Peter Parham, and Frances M. Brodsky PMCID: PMC1091751 Genetics Insights into TOR function and rapamycin response: Chemical genomic profiling by using a high-density cell array method Michael W. Xie, Fulai Jin, Heejun Hwang, Seungmin Hwang, Vikram Anand, Mara C. Duncan, and Jing Huang PMCID: PMC1091748 Genomewide production of multipurpose alleles for the functional analysis of the mouse genome Frank Schnütgen, Silke De-Zolt, Petra Van Sloun, Melanie Hollatz, Thomas Floss, Jens Hansen, Joachim Altschmied, Claudia Seisenberger, Norbert B. Ghyselinck, Patricia Ruiz, Pierre Chambon, Wolfgang Wurst, and Harald von Melchner PMCID: PMC1129123 From the Cover:
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Gregory S. Hageman, Don H. Anderson, Lincoln V. Johnson, Lisa S. Hancox, Andrew J. Taiber, Lisa I. Hardisty, Jill L. Hageman, Heather A. Stockman, James D. Borchardt, Karen M. Gehrs, Richard J. H. Smith, Giuliana Silvestri, Stephen R. Russell, Caroline C. W. Klaver, Irene Barbazetto, Stanley Chang, Lawrence A. Yannuzzi, Gaetano R. Barile, John C. Merriam, R. Theodore Smith, Adam K. Olsh, Julie Bergeron, Jana Zernant, Joanna E. Merriam, Bert Gold, Michael Dean, and Rando Allikmets PMCID: PMC1088171 Immunology Chromosomal clustering of genes controlled by the aire transcription factor Jonathan B. Johnnidis, Emily S. Venanzi, Debra J. Taxman, Jenny P.-Y. Ting, Christophe O. Benoist, and Diane J. Mathis PMCID: PMC1129145 HIV-1-specific IFN-γ/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells Simone C. Zimmerli, Alexandre Harari, Cristina Cellerai, Florence Vallelian, Pierre-Alexandre Bart, and Giuseppe Pantaleo PMCID: PMC1088398 Laser-capture microdissection of plasma cells from subacute sclerosing panencephalitis brain reveals intrathecal disease-relevant antibodies Mark P. Burgoon, Kathryne M. Keays, Gregory P. Owens, Alanna M. Ritchie, Pradeep R. Rai, Carlyne D. Cool, and Donald H. Gilden PMCID: PMC1129126 Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway Sifeng Chen, Matthias H. Kapturczak, Clive Wasserfall, Olena Y. Glushakova, Martha Campbell-Thompson, Jessy S. Deshane, Reny Joseph, Pedro E. Cruz, William W. Hauswirth, Kirsten M. Madsen, Byron P. Croker, Kenneth I. Berns, Mark A. Atkinson, Terence R. Flotte, C. Craig Tisher, and Anupam Agarwal PMCID: PMC1090475 The Toll pathway is important for an antiviral response in Drosophila Robert A. Zambon, Madhumitha Nandakumar, Vikram N. Vakharia, and Louisa P. Wu PMCID: PMC1129099 Coevolution of TCR-MHC interactions: Conserved MHC tertiary structure is not sufficient for interactions with the TCR Hye-Jung Kim, Donglin Guo, and Derek B. Sant'Angelo PMCID: PMC1091755 Serum IgG mediates mucosal immunity against rotavirus infection Larry E. Westerman, Harold M. McClure, Baoming Jiang, Jeffrey W. Almond, and Roger I. Glass PMCID: PMC1129131 Medical Sciences Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception Noam Zelcer, Koen van de Wetering, Michel Hillebrand, Elise Sarton, Annemieke Kuil, Peter R. Wielinga, Thomas Tephly, Albert Dahan, Jos H. Beijnen, and Piet Borst PMCID: PMC1091780 Utility of siRNA against Keap1 as a strategy to stimulate a cancer chemopreventive phenotype Tim W. P. Devling, Christopher D. Lindsay, Lesley I. McLellan, Michael McMahon, and John D. Hayes PMCID: PMC1091750 c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver Esther Baena, Alberto Gandarillas, Mireia Vallespinós, Jennifer Zanet, Oriol Bachs, Clara Redondo, Isabel Fabregat, Carlos Martinez-A., and Ignacio Moreno de Alborán PMCID: PMC1129100 Recombinant granulocyte colony-stimulating factor-transferrin fusion protein as an oral myelopoietic agent Yun Bai, David K. Ann, and Wei-Chiang Shen PMCID: PMC1129103 The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells Jonathan C. Schisler, Per Bo Jensen, David G. Taylor, Thomas C. Becker, Filip Krag Knop, Shiro Takekawa, Michael German, Gordon C. Weir, Danhong Lu, Raghavendra G. Mirmira, and Christopher B. Newgard PMCID: PMC1091752 Microbiology Predicted highly expressed genes in archaeal genomes Samuel Karlin, Jan Mrázek, Jiong Ma, and Luciano Brocchieri PMCID: PMC1129124 Genomic and proteomic comparisons between bacterial and archaeal genomes and related comparisons with the yeast and fly genomes Samuel Karlin, Luciano Brocchieri, Allan Campbell, Martha Cyert, and Jan Mrázek PMCID: PMC1129125 Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella Eric W. Schmidt, James T. Nelson, David A. Rasko, Sebastian Sudek, Jonathan A. Eisen, Margo G. Haygood, and Jacques Ravel PMCID: PMC1091749 Cellulose utilization by Clostridium thermocellum: Bioenergetics and hydrolysis product assimilation Yi-Heng Percival Zhang and Lee R. Lynd PMCID: PMC1129095 Yeast genome-wide screen reveals dissimilar sets of host genes affecting replication of RNA viruses Tadas Panavas, Elena Serviene, Jeremy Brasher, and Peter D. Nagy PMCID: PMC1129141 From the Cover:
Global divergence of microbial genome sequences mediated by propagating fronts Kalin Vetsigian and Nigel Goldenfeld PMCID: PMC1129147 Neuroscience Prefrontal cortex and flexible cognitive control: Rules without symbols Nicolas P. Rougier, David C. Noelle, Todd S. Braver, Jonathan D. Cohen, and Randall C. O'Reilly PMCID: PMC1129132 Noncholinergic excitatory actions of motoneurons in the neonatal mammalian spinal cord George Z. Mentis, Francisco J. Alvarez, Agnes Bonnot, Dannette S. Richards, David Gonzalez-Forero, Ricardo Zerda, and Michael J. O'Donovan PMCID: PMC1091756 Functional organization of human occipital-callosal fiber tracts Robert F. Dougherty, Michal Ben-Shachar, Roland Bammer, Alyssa A. Brewer, and Brian A. Wandell PMCID: PMC1129102 Brain response to putative pheromones in homosexual men Ivanka Savic, Hans Berglund, and Per Lindström PMCID: PMC1129091 The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus Harald Rösch, Rüdiger Schweigreiter, Tobias Bonhoeffer, Yves-Alain Barde, and Martin Korte PMCID: PMC1129133 G protein-dependent presynaptic inhibition mediated by AMPA receptors at the calyx of Held Hideki Takago, Yukihiro Nakamura, and Tomoyuki Takahashi PMCID: PMC1129093 Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate Todd T. Kroll and Dennis D. M. O'Leary PMCID: PMC1129108 Pharmacology Selective anxiolysis produced by ocinaplon, a GABAA receptor modulator A. Lippa, P. Czobor, J. Stark, B. Beer, E. Kostakis, M. Gravielle, S. Bandyopadhyay, S. J. Russek, T. T. Gibbs, D. H. Farb, and P. Skolnick PMCID: PMC1129138 Physiology Alternative Gnas gene products have opposite effects on glucose and lipid metabolism Min Chen, Oksana Gavrilova, Jie Liu, Tao Xie, Chuxia Deng, Annie T. Nguyen, Lisa M. Nackers, Javier Lorenzo, Laura Shen, and Lee S. Weinstein PMCID: PMC1129092 Population Biology Phylogeography of Barbary macaques (Macaca sylvanus) and the origin of the Gibraltar colony Lara Modolo, Walter Salzburger, and Robert D. Martin PMCID: PMC1129121 Social Sciences Economic Sciences Emotion expression in human punishment behavior Erte Xiao and Daniel Houser PMCID: PMC1129129 |
