A central role for ciliary neurotrophic factor?

The molecular machinery for secretion is conserved from yeast to neurons.

Bioconversion of chitin to chitosan: purification and characterization of chitin deacetylase from Mucor rouxii.

Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity.

Identification and analysis of all components of a gel retardation assay by combination with immunoblotting.

Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity.

Participation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3.

Hepoxilin A3 is the endogenous lipid mediator opposing hypotonic swelling of intact human platelets.

Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts.

Technique for in situ measurement of calcium in intracellular inositol 1,4,5-trisphosphate-sensitive stores using the fluorescent indicator mag-fura-2.

A murine retrovirus induces proliferation of unique lymphoid cell lines expressing T-cell-receptor structures utilizing common variable region alpha and beta chain genes.

Mycobacterium tuberculosis expresses two chaperonin-60 homologs.

Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture.

Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production.

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration.

Insulin receptor isotype expression correlates with risk of non-insulin-dependent diabetes.

Function of yeast cytoplasmic C1-tetrahydrofolate synthase.

Bradyrhizobium japonicum rhizobitoxine genes and putative enzyme functions: expression requires a translational frameshift.

Role of oxygen vs. glucose in energy metabolism in a mammary carcinoma perfused ex vivo: direct measurement by 31P NMR.

Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes.

Protein kinases in divergent eukaryotes: identification of protein kinase activities regulated during trypanosome development.

Cholesterol deprivation affects the fluorescence properties of a ceramide analog at the Golgi apparatus of living cells.

Transposition of an Alu-containing element induced by DNA-advanced glycosylation endproducts.

Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events.

Recognition of vaccinia virus-encoded major histocompatibility complex class I antigens by virus immune cytotoxic T cells is independent of the polymorphism of the peptide transporters.

Molecular basis of genetic polymorphism in major histocompatibility complex-linked proteasome gene (Lmp-2).

p70 lupus autoantigen binds the enhancer of the T-cell receptor beta-chain gene.

Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeat.

Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

Learning selectively increases protein kinase C substrate phosphorylation in specific regions of the chick brain.

Adenine nucleoside diphosphates block adaptation of mechanoelectrical transduction in hair cells.

Cocatalytic zinc motifs in enzyme catalysis.

Isolation of interleukin 2-induced immediate-early genes.

Vimentin mRNA location changes during muscle development.

Homeobox genes are expressed in the retina and brain of adult goldfish.

Rate variation of protein and mitochondrial DNA evolution as revealed by sea urchins separated by the isthmus of Panama.

A dominant-negative mutant of Max that inhibits sequence-specific DNA binding by Myc proteins.

Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter.

Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis.

Transcription-driven site-specific DNA recombination in vitro.

Alteration of the cleavage distance of Fok I restriction endonuclease by insertion mutagenesis.

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.

Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma.

Class II-positive hematopoietic cells cannot mediate positive selection of CD4+ T lymphocytes in class II-deficient mice.

HMT, encoded by H-2M3, is a neoclassical major histocompatibility class I antigen.

Bone lead content assessed by L-line x-ray fluorescence in lead-exposed and non-lead-exposed suburban populations in the United States.

Attempts to restore scrapie prion infectivity after exposure to protein denaturants.

Fragmentation and dispersal of Golgi proteins and redistribution of glycoproteins and glycolipids processed through the Golgi apparatus after infection with herpes simplex virus 1.

Chemical suppression of a subpopulation of primitive hematopoietic progenitor cells: 1,3-butadiene produces a hematopoietic defect similar to steel or white spotted mutations in mice.

Calmodulin and calmodulin-binding proteins in hair bundles.

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice.

Mutation of p53 in primary biopsy material and cell lines from Hodgkin disease.

Kedarcidin chromophore: an enediyne that cleaves DNA in a sequence-specific manner.

Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma.

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase.

Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice.

Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

The APC gene product in normal and tumor cells.

Antibody-promoted dimerization bypasses the regulation of DNA binding by the heme domain of the yeast transcriptional activator HAP1.

Cloning of the cDNA encoding a myosin heavy chain B isoform of Xenopus nonmuscle myosin with an insert in the head region.

Transcription initiation factor activity of vaccinia virus capping enzyme is independent of mRNA guanylylation.

Bovine papilloma virus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin.

Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1(IX) collagen chains with a central deletion.

High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells.

Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.

Endothelial cells are required for the cAMP regulation of cardiac contractile proteins.

Purification, characterization, and cDNA cloning of an NADPH-cytochrome P450 reductase from mung bean.

Muscle-specific trk-related receptor with a kringle domain defines a distinct class of receptor tyrosine kinases.

Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells.

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

Rhabdomyosarcoma arising in transgenic mice harboring the beta-globin locus control region fused with simian virus 40 large T antigen gene.

Opioid peptides activate phospholipase D and protein kinase C-epsilon in chicken embryo neuron cultures.

Experimental resolution of the free energies of aqueous solvation contributions to ligand-protein binding: quinone-QA site interactions in the photosynthetic reaction center protein.

Relaxase (TraI) of IncP alpha plasmid RP4 catalyzes a site-specific cleaving-joining reaction of single-stranded DNA.

Crystal structure of CATGGCCATG and its implications for A-tract bending models.

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

Biocatalytic synthesis of acrylates in supercritical fluids: tuning enzyme activity by changing pressure.

Expression of the major protein kinase C substrate, the acidic 80-kilodalton myristoylated alanine-rich C kinase substrate, increases sharply when Swiss 3T3 cells move out of cycle and enter G0.

cDNA for R-cognin: homology with a multifunctional protein.

Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase.

Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.

Chemical and molecular regulation of enzymes that detoxify carcinogens.

Molecular characterization of an operon required for pertussis toxin secretion.

Electrophysiological tests of neural models: evidence for nonlinear binocular interactions in humans.

The sluggish-A gene of Drosophila melanogaster is expressed in the nervous system and encodes proline oxidase, a mitochondrial enzyme involved in glutamate biosynthesis.

Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses.

Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants.

Observing the helical geometry of double-stranded DNA in solution by fluorescence resonance energy transfer.

Sites of predicted stress-induced DNA duplex destabilization occur preferentially at regulatory loci.

Potential role for a FTZ-F1 steroid receptor superfamily member in the control of Drosophila metamorphosis.

Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes.

Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen.

Direct coupling of opioid receptors to both stimulatory and inhibitory guanine nucleotide-binding proteins in F-11 neuroblastoma-sensory neuron hybrid cells.

In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases.

In vitro assembly of multiprotein complexes containing alpha, beta, and gamma tubulin, heat shock protein HSP70, and elongation factor 1 alpha.

Carbohydrate binding activities of Bradyrhizobium japonicum: unipolar localization of the lectin BJ38 on the bacterial cell surface.

Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow.

An 83-nucleotide promoter of the acetylcholine receptor epsilon-subunit gene confers preferential synaptic expression in mouse muscle.

Presumptive Renshaw cells contain decreased calbindin during recovery from sciatic nerve lesions.

Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans.

Molecular cloning and expression of cDNA for mammalian translation initiation factor 5.

Two distinct gene subfamilies within the family of cysteine protease genes.

Ca2+ and Mn2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells.

Association of GAD-65, but not of GAD-67, with the Golgi complex of transfected Chinese hamster ovary cells mediated by the N-terminal region.

Dual control of heat shock response: involvement of a constitutive heat shock element-binding factor.

Synergistic activation of transcription by Escherichia coli cAMP receptor protein.

Soluble antigen profoundly reduces memory B-cell numbers even when given after challenge immunization.

Enteroaggregative Escherichia coli heat-stable enterotoxin 1 represents another subfamily of E. coli heat-stable toxin.

Noninvasive somatosensory homunculus mapping in humans by using a large-array biomagnetometer.

Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.

Redox-activated expression of the cytosolic copper/zinc superoxide dismutase gene in Nicotiana.

Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells.

A monomeric von Willebrand factor fragment, Leu-504—Ser-728, inhibits von Willebrand factor interaction with glycoprotein Ib-IX