Going mobile: microtubule motors and chromosome segregation.

Theoretical prediction of a crystal structure.

The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme.

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.

A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression.

Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density.

Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction.

Observation via one-dimensional 13Calpha NMR of local conformational substates in thermal unfolding equilibria of a synthetic analog of the GCN4 leucine zipper.

The nucleation of receptor-mediated endocytosis.

Human stanniocalcin: a possible hormonal regulator of mineral metabolism.

Correlation between kinetics and RNA splicing of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors in neocortical neurons.

Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.

Steel mutant mice are deficient in hippocampal learning but not long-term potentiation.

Immune response of HLA-DQ8 transgenic mice to peptides from the third hypervariable region of HLA-DRB1 correlates with predisposition to rheumatoid arthritis.

A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.

Cellular aging, destabilization, and cancer.

Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins.

Anti-idiotypic antibodies mimicking glycoprotein D of herpes simplex virus identify a cellular protein required for virus spread from cell to cell and virus-induced polykaryocytosis.

Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine.

Expression of the fructose transporter GLUT5 in human breast cancer.

The multiple phenotypes of allosteric receptor mutants.

An ATP-activated, ligand-gated ion channel on a cholinergic presynaptic nerve terminal.

Antisense oligodeoxynucleotide inhibition of a swelling-activated cation channel in osteoblast-like osteosarcoma cells.

Structure of a gene encoding a cytosolic acetyl-CoA carboxylase of hexaploid wheat.

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

Numerical vorticity creation based on impulse conservation.

The joining (J) chain is present in invertebrates that do not express immunoglobulins.

Embryonic expression patterns of the neural cell adhesion molecule gene are regulated by homeodomain binding sites.

Midcycle administration of a progesterone synthesis inhibitor prevents ovulation in primates.

Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway.

Chemical specificity and physical properties of the lipid bilayer in the regulation of protein kinase C by anionic phospholipids: evidence for the lack of a specific binding site for phosphatidylserine.

Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy.

FM1-43 dye ultrastructural localization in and release from frog motor nerve terminals.

The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis.

Evolution of chlorophyll and bacteriochlorophyll: the problem of invariant sites in sequence analysis.

Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions.

ARD1, a 64-kDa bifunctional protein containing an 18-kDa GTP-binding ADP-ribosylation factor domain and a 46-kDa GTPase-activating domain.

A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice.

A large-capacity memory system that recognizes the calls and songs of individual birds.

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections.

Single-amino acid substitutions eliminate lysine inhibition of maize dihydrodipicolinate synthase.

Protein degradation and increased mRNAs encoding proteins of the ubiquitin-proteasome proteolytic pathway in BC3H1 myocytes require an interaction between glucocorticoids and acidification.

Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

Nucleotide binding-promoted conformational changes release a nonnative polypeptide from the Escherichia coli chaperonin GroEL.

A general two-process model describes the hydrogen exchange behavior of RNase A in unfolding conditions.

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

Molecular cloning and characterization of SCaMPER, a sphingolipid Ca2+ release-mediating protein from endoplasmic reticulum.

Discontinuous epitopes of hepatitis B surface antigen derived from a filamentous phage peptide library.

Antiangiogenic therapy of transgenic mice impairs de novo tumor growth.

Foldons, protein structural modules, and exons.

T-cell epitope analysis using subtracted expression libraries (TEASEL): application to a 38-kDA autoantigen recognized by T cells from an insulin-dependent diabetic patient.

Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease.

Long-term in vitro correction of alpha-L-iduronidase deficiency (Hurler syndrome) in human bone marrow.

Betidamino acids: versatile and constrained scaffolds for drug discovery.

Characterization of small nontranslated polyadenylylated RNAs in vaccinia virus-infected cells.

Purification and physical properties of the male and female double sex proteins of Drosophila.

A set of genes expressed in response to light in the adult cerebral cortex and regulated during development.

Arrest of endotoxin-induced hypotension by transforming growth factor beta1.

A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis.

Two-hybrid system as a model to study the interaction of beta-amyloid peptide monomers.

Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide.

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation.

Randomness and degrees of irregularity.

Human immunodeficiency virus type 1 and 2 Tat proteins specifically interact with RNA polymerase II.

Cloning the expression of a mammalian gene involved in the reduction of methionine sulfoxide residues in proteins.

Inhibition of G-protein betagamma-subunit functions by phosducin-like protein.

Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C.

Neural tube defects and abnormal brain development in F52-deficient mice.

A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice.

Expression of protein encoded by varicella-zoster virus open reading frame 63 in latently infected human ganglionic neurons.

Cloning, expression, and properties of the microtubule-stabilizing protein STOP.

Enhanced and accelerated lymphoproliferation in Fas-null mice.

Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage.

Azotobacter vinelandii NIFL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensitive switch.

Anticoagulant repertoire of the hookworm Ancylostoma caninum.

The terminal Paleozoic fungal event: evidence of terrestrial ecosystem destabilization and collapse.

Recognition of diverse sequences by class I zinc fingers: asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich elements.

Tumor dormancy and cell signaling: anti-mu-induced apoptosis in human B-lymphoma cells is not caused by an APO-1-APO-1 ligand interaction.

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus.

Factor XII-induced mitogenesis is mediated via a distinct signal transduction pathway that activates a mitogen-activated protein kinase.

Expression of the C terminus of the amyloid precursor protein alters growth factor responsiveness in stably transfected PC12 cells.

Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.

An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae.

Prevention of diabetic alterations in transgenic mice overexpressing Myc in the liver.

Calmodulin controls adaptation of mechanoelectrical transduction by hair cells of the bullfrog's sacculus.

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.

The rate constant of photoinhibition, measured in lincomycin-treated leaves, is directly proportional to light intensity.

Z-membranes: artificial organelles for overexpressing recombinant integral membrane proteins.

Close correspondence between the action spectra for the blue light responses of the guard cell and coleoptile chloroplasts, and the spectra for blue light-dependent stomatal opening and coleoptile phototropism.

The contagion indicator hypothesis for parasite-mediated sexual selection.

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.