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Trans Am Ophthalmol Soc. 2007 December; 105: 252–271.
PMCID: PMC2258122
MONOCULAR DIPLOPIA DUE TO SPHEROCYLINDRICAL REFRACTIVE ERRORS (AN AMERICAN OPHTHALMOLOGICAL SOCIETY THESIS)
Steven M. Archer, MD
From the Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor
Abstract

Purpose
Ordinary spherocylindrical refractive errors have been recognized as a cause of monocular diplopia for over a century, yet explanation of this phenomenon using geometrical optics has remained problematic. This study tests the hypothesis that the diffraction theory treatment of refractive errors will provide a more satisfactory explanation of monocular diplopia.

Methods
Diffraction theory calculations were carried out for modulation transfer functions, point spread functions, and line spread functions under conditions of defocus, astigmatism, and mixed spherocylindrical refractive errors. Defocused photographs of inked and projected black lines were made to demonstrate the predicted consequences of the theoretical calculations.

Results
For certain amounts of defocus, line spread functions resulting from spherical defocus are predicted to have a bimodal intensity distribution that could provide the basis for diplopia with line targets. Multimodal intensity distributions are predicted in point spread functions and provide a basis for diplopia or polyopia of point targets under conditions of astigmatism. The predicted doubling effect is evident in defocused photographs of black lines, but the effect is not as robust as the subjective experience of monocular diplopia.

Conclusions
Monocular diplopia due to ordinary refractive errors can be predicted from diffraction theory. Higher-order aberrations—such as spherical aberration—are not necessary but may, under some circumstances, enhance the features of monocular diplopia. The physical basis for monocular diplopia is relatively subtle, and enhancement by neural processing is probably needed to account for the robustness of the percept.