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Abnormal Surge in Brain Development Occurs in Teens and Young Adults with Schizophrenia
July 8, 2008 • Science Update
Schizophrenia may occur, in part, because brain development goes awry during adolescence and young adulthood, when the brain is eliminating some connections between cells as a normal part of maturation, results of a study suggest. The new report appears online July 8, 2008 in Molecular Psychiatry.
NIMH Schizophrenia Initiative Featured in Biological Psychiatry
July 3, 2008 • Science Update
An NIMH initiative to fill the gap between advances in basic cognitive neuroscience and practical clinical applications for patients with schizophrenia is the topic of the July 1, 2008 issue of Biological Psychiatry. It contains eight articles on the Cognitive Neuroscience Approaches to the Treatment of Impaired Cognition in Schizophrenia (CNTRICS) initiative, including a commentary, and descriptions of meetings related to the effort.
HIV-associated Neurological Disease Prevalent in Asia-Pacific Region
July 1, 2008 • Science Update
A new study finds a significant rate of HIV-related neurological disease among HIV-positive populations living in the Asian-Pacific region.
Couples-based Intervention May Limit HIV Transmission in African Countries
June 27, 2008 • Science Update
A shift to a couples-based intervention for married and cohabiting couples in urban Zambia and Rwanda could prevent up to 60 percent of new HIV infections that would otherwise occur, according to an NIMH-funded study published June 27, 2008, in The Lancet.
Mice Expressing Human Genes Bred to Help Unravel Mental Disorders
June 26, 2008 • Science Update
New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH's Division of Neuroscience and Basic Behavioral Science.
New Grant Supports Stem Cell-Derived Model of Autism-Related Illness
June 26, 2008 • Science Update
For the first time, researchers are developing a test tube model of Rett syndrome, a debilitating autism-like illness, in neurons derived from human embryonic stem cells. The study, recently funded by a grant from NIMH’s Division of Neuroscience and Basic Behavioral Science, addresses a crucial gap in understanding the workings of the rare autism spectrum disorder.
Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others
June 23, 2008 • Science Update
Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published online ahead of print June 2, 2008, in the American Journal of Psychiatry.
New Grant Aims to Overcome Obesity in People with Serious Mental Illness
June 20, 2008 • Science Update
A new grant funded by NIMH will test the effectiveness of a promising intervention designed to help people with serious mental illness (SMI) who are overweight or obese lose weight and keep it off.
Anxious Youth Have Disturbed Brain Responses When Looking at Angry Faces
June 20, 2008 • Science Update
When looking at angry faces so quickly that they are hardly aware of seeing them, youth with generalized anxiety disorder (GAD) have unchecked activity in the brain’s fear center, say NIMH researchers.
Potential New Target Found for Developing Medications to Treat Bipolar Disorder
June 20, 2008 • Science Update
Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists.
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