| | This journal provides immediate access to some articles. Perspective Chromosome Mechanics and Meiotic Engine Maintenance Michael E. Dresser PLoS Genet. 2008 September; 4(9): e1000210. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000210.PMCID: PMC2533404 Review A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker Warren J. Ewens, Mingyao Li, and Richard S. Spielman PLoS Genet. 2008 September; 4(9): e1000180. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000180.PMCID: PMC2528965 Research Articles Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2 Carlos F. Pereira, Rémi Terranova, Natalie K. Ryan, Joana Santos, Kelly J. Morris, Wei Cui, Matthias Merkenschlager, and Amanda G. Fisher PLoS Genet. 2008 September; 4(9): e1000170. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000170.PMCID: PMC2527997 Identification of Neural Crest and Glial Enhancers at the Mouse Sox10 Locus through Transgenesis in Zebrafish Anthony Antonellis, Jimmy L. Huynh, Shih-Queen Lee-Lin, Ryan M. Vinton, Gabriel Renaud, Stacie K. Loftus, Gene Elliot, Tyra G. Wolfsberg, Eric D. Green, Andrew S. McCallion, and William J. Pavan PLoS Genet. 2008 September; 4(9): e1000174. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000174.PMCID: PMC2518861 Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms Celia Payen, Romain Koszul, Bernard Dujon, and Gilles Fischer PLoS Genet. 2008 September; 4(9): e1000175. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000175.PMCID: PMC2518615 Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response Julie M. Koeman, Ryan C. Russell, Min-Han Tan, David Petillo, Michael Westphal, Katherine Koelzer, Julie L. Metcalf, Zhongfa Zhang, Daisuke Matsuda, Karl J. Dykema, Heather L. Houseman, Eric J. Kort, Laura L. Furge, Richard J. Kahnoski, Stéphane Richard, Annick Vieillefond, Pamela J. Swiatek, Bin Tean Teh, Michael Ohh, and Kyle A. Furge PLoS Genet. 2008 September; 4(9): e1000176. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000176.PMCID: PMC2518213 A Sox10 Expression Screen Identifies an Amino Acid Essential for Erbb3 Function Kristina Buac, Dawn E. Watkins-Chow, Stacie K. Loftus, Denise M. Larson, Arturo Incao, Gretchen Gibney, and William J. Pavan PLoS Genet. 2008 September; 4(9): e1000177. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000177.PMCID: PMC2518866 Stability and Dynamics of Polycomb Target Sites in Drosophila Development Camilla Kwong, Boris Adryan, Ian Bell, Lisa Meadows, Steven Russell, J. Robert Manak, and Robert White PLoS Genet. 2008 September; 4(9): e1000178. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000178.PMCID: PMC2525605 Genetic Modifiers of MeCP2 Function in Drosophila Holly N. Cukier, Alma M. Perez, Ann L. Collins, Zhaolan Zhou, Huda Y. Zoghbi, and Juan Botas PLoS Genet. 2008 September; 4(9): e1000179. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000179.PMCID: PMC2518867 Is Mate Choice in Humans MHC-Dependent? Raphaëlle Chaix, Chen Cao, and Peter Donnelly PLoS Genet. 2008 September; 4(9): e1000184. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000184.PMCID: PMC2519788 The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii Magali Lescot, Stéphane Audic, Catherine Robert, Thi Tien Nguyen, Guillaume Blanc, Sally J. Cutler, Patrick Wincker, Arnaud Couloux, Jean-Michel Claverie, Didier Raoult, and Michel Drancourt PLoS Genet. 2008 September; 4(9): e1000185. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000185.PMCID: PMC2525819 MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis J. Kim Holloway, James Booth, Winfried Edelmann, Clare H. McGowan, and Paula E. Cohen PLoS Genet. 2008 September; 4(9): e1000186. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000186.PMCID: PMC2525838 The Genomic Distribution and Function of Histone Variant HTZ-1 during C. elegans Embryogenesis Christina M. Whittle, Karissa N. McClinic, Sevinc Ercan, Xinmin Zhang, Roland D. Green, William G. Kelly, and Jason D. Lieb PLoS Genet. 2008 September; 4(9): e1000187. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000187.PMCID: PMC2522285 Csm4, in Collaboration with Ndj1, Mediates Telomere-Led Chromosome Dynamics and Recombination during Yeast Meiosis Jennifer J. Wanat, Keun P. Kim, Romain Koszul, Sarah Zanders, Beth Weiner, Nancy Kleckner, and Eric Alani PLoS Genet. 2008 September; 4(9): e1000188. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000188.PMCID: PMC2533701 Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling in Response to DNA Interstrand Crosslinks, while MSH2 Functions in DNA Repair Qi Wu and Karen M. Vasquez PLoS Genet. 2008 September; 4(9): e1000189. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000189.PMCID: PMC2526179 The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A. Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez, Susana Gonzalo, Yi Zhang, En Li, and Taiping Chen PLoS Genet. 2008 September; 4(9): e1000190. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000190.PMCID: PMC2527135 Evolution of a New Function by Degenerative Mutation in Cephalochordate Steroid Receptors Jamie T. Bridgham, Justine E. Brown, Adriana Rodríguez-Marí, Julian M. Catchen, and Joseph W. Thornton PLoS Genet. 2008 September; 4(9): e1000191. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000191.PMCID: PMC2527136 A Mouse Model of Harlequin Ichthyosis Delineates a Key Role for Abca12 in Lipid Homeostasis Ian Smyth, Douglas F. Hacking, Adrienne A. Hilton, Nigora Mukhamedova, Peter J. Meikle, Sarah Ellis, Keith Slattery, Janelle E. Collinge, Carolyn A. de Graaf, Melanie Bahlo, Dmitri Sviridov, Benjamin T. Kile, and Douglas J. Hilton PLoS Genet. 2008 September; 4(9): e1000192. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000192.PMCID: PMC2529452 Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis Nicola J. Rutherford, Yong-Jie Zhang, Matt Baker, Jennifer M. Gass, NiCole A. Finch, Ya-Fei Xu, Heather Stewart, Brendan J. Kelley, Karen Kuntz, Richard J. P. Crook, Jemeen Sreedharan, Caroline Vance, Eric Sorenson, Carol Lippa, Eileen H. Bigio, Daniel H. Geschwind, David S. Knopman, Hiroshi Mitsumoto, Ronald C. Petersen, Neil R. Cashman, Mike Hutton, Christopher E. Shaw, Kevin B. Boylan, Bradley Boeve, Neill R. Graff-Radford, Zbigniew K. Wszolek, Richard J. Caselli, Dennis W. Dickson, Ian R. Mackenzie, Leonard Petrucelli, and Rosa Rademakers PLoS Genet. 2008 September; 4(9): e1000193. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000193.PMCID: PMC2527686 corona Is Required for Higher-Order Assembly of Transverse Filaments into Full-Length Synaptonemal Complex in Drosophila Oocytes Scott L. Page, Radhika S. Khetani, Cathleen M. Lake, Rachel J. Nielsen, Jennifer K. Jeffress, William D. Warren, Sharon E. Bickel, and R. Scott Hawley PLoS Genet. 2008 September; 4(9): e1000194. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000194.PMCID: PMC2529403 Missense Mutation in Exon 2 of SLC36A1 Responsible for Champagne Dilution in Horses Deborah Cook, Samantha Brooks, Rebecca Bellone, and Ernest Bailey PLoS Genet. 2008 September; 4(9): e1000195. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000195.PMCID: PMC2535566 Csm4-Dependent Telomere Movement on Nuclear Envelope Promotes Meiotic Recombination Hiromichi Kosaka, Miki Shinohara, and Akira Shinohara PLoS Genet. 2008 September; 4(9): e1000196. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000196.PMCID: PMC2533704 Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected Amy Murphy, Scott T. Weiss, and Christoph Lange PLoS Genet. 2008 September; 4(9): e1000197. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000197.PMCID: PMC2529406 An Approximate Bayesian Estimator Suggests Strong, Recurrent Selective Sweeps in Drosophila Jeffrey D. Jensen, Kevin R. Thornton, and Peter Andolfatto PLoS Genet. 2008 September; 4(9): e1000198. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000198.PMCID: PMC2529407 Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice Rupert Öllinger, Andrew J. Childs, Hannah M. Burgess, Robert M. Speed, Pia R. Lundegaard, Nicola Reynolds, Nicola K. Gray, Howard J. Cooke, and Ian R. Adams PLoS Genet. 2008 September; 4(9): e1000199. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000199.PMCID: PMC2531233 Sex-Specific Genetic Structure and Social Organization in Central Asia: Insights from a Multi-Locus Study Laure Ségurel, Begoña Martínez-Cruz, Lluis Quintana-Murci, Patricia Balaresque, Myriam Georges, Tatiana Hegay, Almaz Aldashev, Firuza Nasyrova, Mark A. Jobling, Evelyne Heyer, and Renaud Vitalis PLoS Genet. 2008 September; 4(9): e1000200. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000200.PMCID: PMC2535577 FtsK-Dependent Dimer Resolution on Multiple Chromosomes in the Pathogen Vibrio cholerae Marie-Eve Val, Sean P. Kennedy, Meriem El Karoui, Laetitia Bonné, Fabien Chevalier, and François-Xavier Barre PLoS Genet. 2008 September; 4(9): e1000201. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000201.PMCID: PMC2533119 Sex-Biased Evolutionary Forces Shape Genomic Patterns of Human Diversity Michael F. Hammer, Fernando L. Mendez, Murray P. Cox, August E. Woerner, and Jeffrey D. Wall PLoS Genet. 2008 September; 4(9): e1000202. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000202.PMCID: PMC2538571 Tracing the Source of Campylobacteriosis Daniel J. Wilson, Edith Gabriel, Andrew J. H. Leatherbarrow, John Cheesbrough, Steven Gee, Eric Bolton, Andrew Fox, Paul Fearnhead, C. Anthony Hart, and Peter J. Diggle PLoS Genet. 2008 September; 4(9): e1000203. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000203.PMCID: PMC2538567 Intronic Alus Influence Alternative Splicing Galit Lev-Maor, Oren Ram, Eddo Kim, Noa Sela, Amir Goren, Erez Y. Levanon, and Gil Ast PLoS Genet. 2008 September; 4(9): e1000204. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000204.PMCID: PMC2533698 Corrections Correction: WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q. Hoa, Minoru Okada, Sadiqur R. Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, and Yousuke Takahama PLoS Genet. 2008 September; 4(9): 10.1371/annotation/6683988c-4647-4550-88e3-e8ba052f7916. Published online 2008 September 4. doi: 10.1371/annotation/6683988c-4647-4550-88e3-e8ba052f7916.PMCID: PMC2645275 Corrects: Norimasa Iwanami, et al. WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development. PLoS Genet. 2008 August; 4(8): e1000171. Correction: Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated EGLN2-Mediated Oxygen-Sensing Response Julie M. Koeman, Ryan C. Russell, Min-Han Tan, David Petillo, Michael Westphal, Katherine Koelzer, Julie L. Metcalf, Zhongfa Zhang, Daisuke Matsuda, Karl J. Dykema, Heather L. Houseman, Eric J. Kort, Laura L. Furge, Richard J. Kahnoski, Stéphane Richard, Annick Vieillefond, Pamela J. Swiatek, Bin Tean Teh, Michael Ohh, and Kyle A. Furge PLoS Genet. 2008 September; 4(9): 10.1371/annotation/7f57058f-cc02-45a6-bfab-a835619e3916. Published online 2008 September 18. doi: 10.1371/annotation/7f57058f-cc02-45a6-bfab-a835619e3916.PMCID: PMC2648618 Corrects: Julie M. Koeman, et al. Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response. PLoS Genet. 2008 September; 4(9): e1000176. |