Redistribution of Fat and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

This study is ongoing, but not recruiting participants.

Sponsors and Collaborators:	Johns Hopkins University National Institutes of Health (NIH)
Information provided by:	Johns Hopkins University
ClinicalTrials.gov Identifier:	NCT00244803

Purpose

The purpose of this study is to learn whether HIV-infected patients have blood abnormalities which could lead to heart attack or stroke, and to find out what factors may contribute to these abnormalities.

Condition
Human Immunodeficiency Virus

MedlinePlus related topics: AIDS

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study
Official Title:	Redistribution and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

Further study details as provided by Johns Hopkins University:

Estimated Enrollment:	101
Study Start Date:	January 2005

Detailed Description:

This research is being done to learn whether HIV-infected patients have abnormalities in their blood vessels that could eventually lead to heart attack or stroke (atherosclerosis), in how fat is distributed in their body and in how their body handles fat and sugars. If there are abnormalities, this study will also try to find out what factors may contribute to those abnormalitites.

People who participated in FRAM 1 may join FRAM 2.

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:18-65 years old, previous FRAM 1 participant, HIV positive -

Exclusion Criteria:Artificial knee or hip replacement or Harrington rod.Metal objects in the body.Pregnancy. Breastfeeding or less than 3 months after breastfeeding.Weight more than 300 pounds.On insulin, pancreatic enzymes, or thioridazine.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00244803

Locations

United States, Maryland
Johns Hopkins University, The Clinical Trials Unit
Baltimore, Maryland, United States, 21205

Sponsors and Collaborators

Johns Hopkins University

National Institutes of Health (NIH)

Investigators

Principal Investigator:

Joseph Cofrancesco Jr., M.D.

Johns Hopkins University

More Information

Study ID Numbers:	03-07-02-01
Study First Received:	October 25, 2005
Last Updated:	October 25, 2005
ClinicalTrials.gov Identifier:	NCT00244803
Health Authority:	United States: Institutional Review Board

Keywords provided by Johns Hopkins University:

Human Immunodeficiency Virus
FRAM 1

Study placed in the following topic categories:

Virus Diseases
Sexually Transmitted Diseases, Viral
HIV Infections
Sexually Transmitted Diseases

Acquired Immunodeficiency Syndrome
Retroviridae Infections
Immunologic Deficiency Syndromes

Additional relevant MeSH terms:

RNA Virus Infections
Slow Virus Diseases
Immune System Diseases
Lentivirus Infections

ClinicalTrials.gov processed this record on January 16, 2009