U.S. National Institutes of Health

National Institute of Biomedical Imaging and Bioengineering and the Radiological Society of North America

Websites:
http://www.nibib.nih.gov/publicPage.cfm?pageID=639
http://www.rsna.org/

CIP is collaborating with the Radiological Society of North America (RSNA), the NCI Center for Bioinformatics, and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) on a pilot project called the Reference Image Database to Evaluate Response to Therapy in Lung Cancer (RIDER).

RIDER, which is part of the larger LIDC initiative ( http://imaging.cancer.gov/reportsandpublications/ReportsandPresentations/LungImaging), aims to produce a reference database for researchers, allowing them to develop software and other tools to address the problems of cancer detection, characterization, and response to therapy. This collaborative effort is reducing barriers to research by generating publicly available image databases, with the first prototypes being related to the imaging of lung cancer.

The RIDER pilot project thus far has resulted in an initial Web-accessible resource ( http://imaging.nci.nih.gov/i3/) of serial CT data compatible with the NCI Cancer Biomedical Informatics Grid (caBIG). The proposed expansion of the RIDER project will initially include image and related metadata collected from imaging modalities such as X-ray CT and PET/CT as applied to lung cancer, collected from a wide range of both NCI- and industry-\ supported drug trials. One important industry goal of this resource is to attempt to accelerate FDA approval and the Centers for Medicare & Medicaid Services (CMS) reimbursement of software tools.

RIDER is striving to accomplish all its goals using open-source coding so that researchers can tailor applications to meet their individual specifications and mesh with other applications.