| | Research Articles Induction of Tachykinin Production in Airway Epithelia in Response to Viral Infection James P. Stewart, Anja Kipar, Helen Cox, Catherine Payne, Sylvia Vasiliou, and John P. Quinn PLoS ONE. 2008; 3(3): e1673. Published online 2008 March 5. doi: 10.1371/journal.pone.0001673.PMCID: PMC2248620 Case-Control Study of Fetal Microchimerism and Breast Cancer Vijayakrishna K. Gadi, Kathleen E. Malone, Katherine A. Guthrie, Peggy L. Porter, and J. Lee Nelson PLoS ONE. 2008; 3(3): e1706. Published online 2008 March 5. doi: 10.1371/journal.pone.0001706.PMCID: PMC2248618 Peripherally-Derived BDNF Promotes Regeneration of Ascending Sensory Neurons after Spinal Cord Injury Xing-Yun Song, Fang Li, Feng-He Zhang, Jin-Hua Zhong, and Xin-Fu Zhou PLoS ONE. 2008; 3(3): e1707. Published online 2008 March 5. doi: 10.1371/journal.pone.0001707.PMCID: PMC2246162 Signaling Signatures and Functional Properties of Anti-Human CD28 Superagonistic Antibodies Zoe Waibler, Linda Y. Sender, Camilla Merten, Roland Hartig, Stefanie Kliche, Matthias Gunzer, Peter Reichardt, Ulrich Kalinke, and Burkhart Schraven PLoS ONE. 2008; 3(3): e1708. Published online 2008 March 5. doi: 10.1371/journal.pone.0001708.PMCID: PMC2246163 SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice Feng Ding, Hong Hua Li, Shengwen Zhang, Nicola M. Solomon, Sally A. Camper, Pinchas Cohen, and Uta Francke PLoS ONE. 2008; 3(3): e1709. Published online 2008 March 5. doi: 10.1371/journal.pone.0001709.PMCID: PMC2248623 SIRT1 Overexpression Antagonizes Cellular Senescence with Activated ERK/S6k1 Signaling in Human Diploid Fibroblasts Jing Huang, Qini Gan, Limin Han, Jian Li, Hai Zhang, Ying Sun, Zongyu Zhang, and Tanjun Tong PLoS ONE. 2008; 3(3): e1710. Published online 2008 March 5. doi: 10.1371/journal.pone.0001710.PMCID: PMC2249701 When Did HIV Incidence Peak in Harare, Zimbabwe? Back-Calculation from Mortality Statistics Ben Lopman and Simon Gregson PLoS ONE. 2008; 3(3): e1711. Published online 2008 March 5. doi: 10.1371/journal.pone.0001711.PMCID: PMC2248619 Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations Taras K. Oleksyk, Kai Zhao, Francisco M. De La Vega, Dennis A. Gilbert, Stephen J. O'Brien, and Michael W. Smith PLoS ONE. 2008; 3(3): e1712. Published online 2008 March 5. doi: 10.1371/journal.pone.0001712.PMCID: PMC2248624 Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity Pernilla Lång, Vanessa van Harmelen, Mikael Rydén, Maria Kaaman, Paolo Parini, Claes Carneheim, A. Ian Cassady, David A. Hume, Göran Andersson, and Peter Arner PLoS ONE. 2008; 3(3): e1713. Published online 2008 March 5. doi: 10.1371/journal.pone.0001713.PMCID: PMC2248616 Ganglion Cell Adaptability: Does the Coupling of Horizontal Cells Play a Role? Karin Dedek, Chethan Pandarinath, Nazia M. Alam, Kerstin Wellershaus, Timm Schubert, Klaus Willecke, Glen T. Prusky, Reto Weiler, and Sheila Nirenberg PLoS ONE. 2008; 3(3): e1714. Published online 2008 March 5. doi: 10.1371/journal.pone.0001714.PMCID: PMC2246161 Heterogeneous Adaptive Trajectories of Small Populations on Complex Fitness Landscapes Daniel E. Rozen, Michelle G. J. L. Habets, Andreas Handel, and J. Arjan G. M. de Visser PLoS ONE. 2008; 3(3): e1715. Published online 2008 March 5. doi: 10.1371/journal.pone.0001715.PMCID: PMC2248617 Relativistic Compression and Expansion of Experiential Time in the Left and Right Space Carmelo Mario Vicario, Patrizia Pecoraro, Patrizia Turriziani, Giacomo Koch, Carlo Caltagirone, and Massimiliano Oliveri PLoS ONE. 2008; 3(3): e1716. Published online 2008 March 5. doi: 10.1371/journal.pone.0001716.PMCID: PMC2248621 A Visual Data Mining Tool that Facilitates Reconstruction of Transcription Regulatory Networks Daniel C. Jupiter and Vincent VanBuren PLoS ONE. 2008; 3(3): e1717. Published online 2008 March 5. doi: 10.1371/journal.pone.0001717.PMCID: PMC2248622 Adaptor SKAP-55 Binds p21ras Activating Exchange Factor RasGRP1 and Negatively Regulates the p21ras-ERK Pathway in T-Cells Helga Schneider, Hongyan Wang, Monika Raab, Elke Valk, Xin Smith, Matt Lovatt, Zhonglin Wu, Braudel Maqueira-Iglesias, Klaus Strebhardt, and Christopher E. Rudd PLoS ONE. 2008; 3(3): e1718. Published online 2008 March 5. doi: 10.1371/journal.pone.0001718.PMCID: PMC2249700 The Effect of Central Loops in miRNA:MRE Duplexes on the Efficiency of miRNA-Mediated Gene Regulation Wenbin Ye, Qing Lv, Chung-Kwun Amy Wong, Sean Hu, Chao Fu, Zhong Hua, Guoping Cai, Guoxi Li, Burton B. Yang, and Yaou Zhang PLoS ONE. 2008; 3(3): e1719. Published online 2008 March 5. doi: 10.1371/journal.pone.0001719.PMCID: PMC2248708 The Balance between Plasmacytoid DC versus Conventional DC Determines Pulmonary Immunity to Virus Infections Joost J. Smit, Dennis M. Lindell, Louis Boon, Mirjam Kool, Bart N. Lambrecht, and Nicholas W. Lukacs PLoS ONE. 2008; 3(3): e1720. Published online 2008 March 5. doi: 10.1371/journal.pone.0001720.PMCID: PMC2249704 Has the DOTS Strategy Improved Case Finding or Treatment Success? An Empirical Assessment Ziad Obermeyer, Jesse Abbott-Klafter, and Christopher J. L. Murray PLoS ONE. 2008; 3(3): e1721. Published online 2008 March 5. doi: 10.1371/journal.pone.0001721.PMCID: PMC2253827 Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target Mariëlle I. Gallegos Ruiz, Karijn Floor, Paul Roepman, José A. Rodriguez, Gerrit A. Meijer, Wolter J. Mooi, Ewa Jassem, Jacek Niklinski, Thomas Muley, Nico van Zandwijk, Egbert F. Smit, Kristin Beebe, Len Neckers, Bauke Ylstra, and Giuseppe Giaccone PLoS ONE. 2008; 3(3): e1722. Published online 2008 March 5. doi: 10.1371/journal.pone.0001722.PMCID: PMC2254495 Transcriptome of Aphanomyces euteiches: New Oomycete Putative Pathogenicity Factors and Metabolic Pathways Elodie Gaulin, Mohammed-Amine Madoui, Arnaud Bottin, Christophe Jacquet, Catherine Mathé, Arnaud Couloux, Patrick Wincker, and Bernard Dumas PLoS ONE. 2008; 3(3): e1723. Published online 2008 March 5. doi: 10.1371/journal.pone.0001723.PMCID: PMC2248709 B Cell Response Is Required for Granuloma Formation in the Early Infection of Schistosoma japonicum Fang Ji, Zhanjie Liu, Jianping Cao, Na Li, Zhijian Liu, Jinxin Zuo, Yan Chen, Xinzhi Wang, and Jian Sun PLoS ONE. 2008; 3(3): e1724. Published online 2008 March 5. doi: 10.1371/journal.pone.0001724.PMCID: PMC2248706 Overestimates of Survival after HAART: Implications for Global Scale-Up Efforts Gregory P. Bisson, Tendani Gaolathe, Robert Gross, Caitlin Rollins, Scarlett Bellamy, Mpho Mogorosi, Ava Avalos, Harvey Friedman, Diana Dickinson, Ian Frank, and Ndwapi Ndwapi PLoS ONE. 2008; 3(3): e1725. Published online 2008 March 5. doi: 10.1371/journal.pone.0001725.PMCID: PMC2254493 Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus Amr H. Sawalha, Ryan Webb, Shizhong Han, Jennifer A. Kelly, Kenneth M. Kaufman, Robert P. Kimberly, Marta E. Alarcón-Riquelme, Judith A. James, Timothy J. Vyse, Gary S. Gilkeson, Chan-Bum Choi, R. Hal Scofield, Sang-Cheol Bae, Swapan K. Nath, and John B. Harley PLoS ONE. 2008; 3(3): e1727. Published online 2008 March 5. doi: 10.1371/journal.pone.0001727.PMCID: PMC2253825 Exploring Action Dynamics as an Index of Paired-Associate Learning Rick Dale, Jennifer Roche, Kristy Snyder, and Ryan McCall PLoS ONE. 2008; 3(3): e1728. Published online 2008 March 5. doi: 10.1371/journal.pone.0001728.PMCID: PMC2253184 Nanofibrous Scaffolds Incorporating PDGF-BB Microspheres Induce Chemokine Expression and Tissue Neogenesis In Vivo Qiming Jin, Guobao Wei, Zhao Lin, James V. Sugai, Samuel E. Lynch, Peter X. Ma, and William V. Giannobile PLoS ONE. 2008; 3(3): e1729. Published online 2008 March 5. doi: 10.1371/journal.pone.0001729.PMCID: PMC2248711 Tempo and Mode of Diversification of Lake Tanganyika Cichlid Fishes Julia J. Day, James A. Cotton, and Timothy G. Barraclough PLoS ONE. 2008; 3(3): e1730. Published online 2008 March 5. doi: 10.1371/journal.pone.0001730.PMCID: PMC2248707 Quantitative Evaluation of DNA Methylation Patterns for ALVE and TVB Genes in a Neoplastic Disease Susceptible and Resistant Chicken Model Ying Yu, Huanmin Zhang, Fei Tian, Larry Bacon, Yuan Zhang, Wensheng Zhang, and Jiuzhou Song PLoS ONE. 2008; 3(3): e1731. Published online 2008 March 5. doi: 10.1371/journal.pone.0001731.PMCID: PMC2254315 Identification and Characterization of a Novel Plasmodium falciparum Merozoite Apical Protein Involved in Erythrocyte Binding and Invasion Thilan Wickramarachchi, Yengkhom S. Devi, Asif Mohmmed, and Virander S. Chauhan PLoS ONE. 2008; 3(3): e1732. Published online 2008 March 5. doi: 10.1371/journal.pone.0001732.PMCID: PMC2253826 Early and Late Pathogenic Events of Newborn Mice Encephalitis Experimentally Induced by Itacaiunas and Curionópolis Bracorhabdoviruses Infection José Antonio Picanço Diniz, Zaire Alves dos Santos, Marcio Augusto Galvão Braga, Ádila Liliane Barros Dias, Daisy Elaine Andrade da Silva, Daniele Barbosa de Almeida Medeiros, Vera Lucia Reis de Souza Barros, Jannifer Oliveira Chiang, Kendra Eyllen de Freitas Zoghbi, Juarez Antônio Simões Quaresma, Christina Maeda Takiya, Vivaldo Moura Neto, Wanderley de Souza, Pedro Fernando da Costa Vasconcelos, and Cristovam Wanderley Picanço Diniz PLoS ONE. 2008; 3(3): e1733. Published online 2008 March 5. doi: 10.1371/journal.pone.0001733.PMCID: PMC2253828 Nonvirally Modified Autologous Primary Hepatocytes Correct Diabetes and Prevent Target Organ Injury in a Large Preclinical Model Nelson K. F. Chen, Jen San Wong, Irene H. C. Kee, Siang Hui Lai, Choon Hua Thng, Wai Har Ng, Robert T. H. Ng, Soo Yong Tan, Shu Yen Lee, Mark E. H. Tan, Jaichandran Sivalingam, Pierce K. H. Chow, and Oi Lian Kon PLoS ONE. 2008; 3(3): e1734. Published online 2008 March 5. doi: 10.1371/journal.pone.0001734.PMCID: PMC2249706 Auditory Cortical Contrast Enhancing by Global Winner-Take-All Inhibitory Interactions Simone Kurt, Anke Deutscher, John M. Crook, Frank W. Ohl, Eike Budinger, Christoph K. Moeller, Henning Scheich, and Holger Schulze PLoS ONE. 2008; 3(3): e1735. Published online 2008 March 5. doi: 10.1371/journal.pone.0001735.PMCID: PMC2253823 Retention of Memory through Metamorphosis: Can a Moth Remember What It Learned As a Caterpillar? Douglas J. Blackiston, Elena Silva Casey, and Martha R. Weiss PLoS ONE. 2008; 3(3): e1736. Published online 2008 March 5. doi: 10.1371/journal.pone.0001736.PMCID: PMC2248710 The Human TPR Protein TTC4 Is a Putative Hsp90 Co-Chaperone Which Interacts with CDC6 and Shows Alterations in Transformed Cells Gilles Crevel, Dorothy Bennett, and Sue Cotterill PLoS ONE. 2008; 3(3): e1737. Published online 2008 March 5. doi: 10.1371/journal.pone.0001737.PMCID: PMC2253824 MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis Katsuhiko Hayashi, Susana M. Chuva de Sousa Lopes, Masahiro Kaneda, Fuchou Tang, Petra Hajkova, Kaiqin Lao, Donal O'Carroll, Partha P. Das, Alexander Tarakhovsky, Eric A. Miska, and M. Azim Surani PLoS ONE. 2008; 3(3): e1738. Published online 2008 March 5. doi: 10.1371/journal.pone.0001738.PMCID: PMC2254191 Estimating Heritabilities and Genetic Correlations: Comparing the ‘Animal Model’ with Parent-Offspring Regression Using Data from a Natural Population Mikael Åkesson, Staffan Bensch, Dennis Hasselquist, Maja Tarka, and Bengt Hansson PLoS ONE. 2008; 3(3): e1739. Published online 2008 March 5. doi: 10.1371/journal.pone.0001739.PMCID: PMC2254494 Architecture of an Antagonistic Tree/Fungus Network: The Asymmetric Influence of Past Evolutionary History Corinne Vacher, Dominique Piou, and Marie-Laure Desprez-Loustau PLoS ONE. 2008; 3(3): e1740. Published online 2008 March 5. doi: 10.1371/journal.pone.0001740.PMCID: PMC2254192 S100A7-Downregulation Inhibits Epidermal Growth Factor-Induced Signaling in Breast Cancer Cells and Blocks Osteoclast Formation Vikram Paruchuri, Anil Prasad, Kevin McHugh, Hari K. Bhat, Kornelia Polyak, and Ramesh K. Ganju PLoS ONE. 2008; 3(3): e1741. Published online 2008 March 5. doi: 10.1371/journal.pone.0001741.PMCID: PMC2254193 Automated 3D Phenotype Analysis Using Data Mining Ilya Plyusnin, Alistair R. Evans, Aleksis Karme, Aristides Gionis, and Jukka Jernvall PLoS ONE. 2008; 3(3): e1742. Published online 2008 March 5. doi: 10.1371/journal.pone.0001742.PMCID: PMC2254194 Hibernation in an Antarctic Fish: On Ice for Winter Hamish A. Campbell, Keiron P. P. Fraser, Charles M. Bishop, Lloyd S. Peck, and Stuart Egginton PLoS ONE. 2008; 3(3): e1743. Published online 2008 March 5. doi: 10.1371/journal.pone.0001743.PMCID: PMC2254195 Frequent Fires in Ancient Shrub Tundra: Implications of Paleorecords for Arctic Environmental Change Philip E. Higuera, Linda B. Brubaker, Patricia M. Anderson, Thomas A. Brown, Alison T. Kennedy, and Feng Sheng Hu PLoS ONE. 2008; 3(3): e1744. Published online 2008 March 5. doi: 10.1371/journal.pone.0001744.PMCID: PMC2254503 Seed Dispersal Anachronisms: Rethinking the Fruits Extinct Megafauna Ate Paulo R. Guimarães, Jr., Mauro Galetti, and Pedro Jordano PLoS ONE. 2008; 3(3): e1745. Published online 2008 March 5. doi: 10.1371/journal.pone.0001745.PMCID: PMC2258420 Association Analysis of the FTO Gene with Obesity in Children of Caucasian and African Ancestry Reveals a Common Tagging SNP Struan F. A. Grant, Mingyao Li, Jonathan P. Bradfield, Cecilia E. Kim, Kiran Annaiah, Erin Santa, Joseph T. Glessner, Tracy Casalunovo, Edward C. Frackelton, F. George Otieno, Julie L. Shaner, Ryan M. Smith, Marcin Imielinski, Andrew W. Eckert, Rosetta M. Chiavacci, Robert I. Berkowitz, and Hakon Hakonarson PLoS ONE. 2008; 3(3): e1746. Published online 2008 March 12. doi: 10.1371/journal.pone.0001746.PMCID: PMC2262153 T Cell Receptor Engagement Triggers Its CD3ε and CD3ζ Subunits to Adopt a Compact, Locked Conformation Ruth M. Risueño, Wolfgang W. A. Schamel, and Balbino Alarcón PLoS ONE. 2008; 3(3): e1747. Published online 2008 March 5. doi: 10.1371/journal.pone.0001747.PMCID: PMC2254190 Laterality and Flight: Concurrent Tests of Side-Bias and Optimality in Flying Tree Swallows James T. Mandel, John M. Ratcliffe, David J. Cerasale, and David W. Winkler PLoS ONE. 2008; 3(3): e1748. Published online 2008 March 12. doi: 10.1371/journal.pone.0001748.PMCID: PMC2254502 Control of Muscle Mitochondria by Insulin Entails Activation of Akt2-mtNOS Pathway: Implications for the Metabolic Syndrome Paola Finocchietto, Fernando Barreyro, Silvia Holod, Jorge Peralta, María C. Franco, Carlos Méndez, Daniela P. Converso, Alvaro Estévez, Maria C. Carreras, and Juan J. Poderoso PLoS ONE. 2008; 3(3): e1749. Published online 2008 March 12. doi: 10.1371/journal.pone.0001749.PMCID: PMC2258147 Swelling-Activated Ca2+ Channels Trigger Ca2+ Signals in Merkel Cells Henry Haeberle, Leigh A. Bryan, Tegy J. Vadakkan, Mary E. Dickinson, and Ellen A. Lumpkin PLoS ONE. 2008; 3(3): e1750. Published online 2008 March 12. doi: 10.1371/journal.pone.0001750.PMCID: PMC2365925 Automatic Physiological Waveform Processing for fMRI Noise Correction and Analysis Daniel J. Kelley, Terrence R. Oakes, Larry L. Greischar, Moo K. Chung, John M. Ollinger, Andrew L. Alexander, Steven E. Shelton, Ned H. Kalin, and Richard J. Davidson PLoS ONE. 2008; 3(3): e1751. Published online 2008 March 12. doi: 10.1371/journal.pone.0001751.PMCID: PMC2268243 Quantitative Trait Loci for Bone Lengths on Chromosome 5 Using Dual Energy X-Ray Absorptiometry Imaging in the Twins UK Cohort Usha Chinappen-Horsley, Glen M. Blake, Ignac Fogelman, Bernet Kato, Kourosh R. Ahmadi, and Tim D. Spector PLoS ONE. 2008; 3(3): e1752. Published online 2008 March 12. doi: 10.1371/journal.pone.0001752.PMCID: PMC2262137 Direct Isolation, Culture and Transplant of Mouse Skeletal Muscle Derived Endothelial Cells with Angiogenic Potential Nicholas Ieronimakis, Gayathri Balasundaram, and Morayma Reyes PLoS ONE. 2008; 3(3): e1753. Published online 2008 March 12. doi: 10.1371/journal.pone.0001753.PMCID: PMC2262143 The Impact of the Human DNA Topoisomerase II C-Terminal Domain on Activity Emma L. Meczes, Kathryn L. Gilroy, Katherine L. West, and Caroline A. Austin PLoS ONE. 2008; 3(3): e1754. Published online 2008 March 12. doi: 10.1371/journal.pone.0001754.PMCID: PMC2262138 DICER-LIKE2 Plays a Primary Role in Transitive Silencing of Transgenes in Arabidopsis Sizolwenkosi Mlotshwa, Gail J. Pruss, Angela Peragine, Matthew W. Endres, Junjie Li, Xuemei Chen, R. Scott Poethig, Lewis H. Bowman, and Vicki Vance PLoS ONE. 2008; 3(3): e1755. Published online 2008 March 12. doi: 10.1371/journal.pone.0001755.PMCID: PMC2262140 Screen for Localized Proteins in Caulobacter crescentus Jay H. Russell and Kenneth C. Keiler PLoS ONE. 2008; 3(3): e1756. Published online 2008 March 12. doi: 10.1371/journal.pone.0001756.PMCID: PMC2262157 Osteopontin and Systemic Lupus Erythematosus Association: A Probable Gene-Gender Interaction Shizhong Han, Joel M. Guthridge, Isaac T. W. Harley, Andrea L. Sestak, Xana Kim-Howard, Kenneth M. Kaufman, Bahram Namjou, Harshal Deshmukh, Gail Bruner, Luis R. Espinoza, Gary S. Gilkeson, John B. Harley, Judith A. James, and Swapan K. Nath PLoS ONE. 2008; 3(3): e1757. Published online 2008 March 12. doi: 10.1371/journal.pone.0001757.PMCID: PMC2258418 Transcriptional Regulation of PIK3CA Oncogene by NF-κB in Ovarian Cancer Microenvironment Nuo Yang, Jia Huang, Joel Greshock, Shun Liang, Andrea Barchetti, Kosei Hasegawa, Sarah Kim, Antonis Giannakakis, Chunsheng Li, Anne O'Brien-Jenkins, Dionyssios Katsaros, Ralf Bützow, George Coukos, and Lin Zhang PLoS ONE. 2008; 3(3): e1758. Published online 2008 March 12. doi: 10.1371/journal.pone.0001758.PMCID: PMC2258145 SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice Gino Boily, Erin L. Seifert, Lisa Bevilacqua, Xiao Hong He, Guillaume Sabourin, Carmen Estey, Cynthia Moffat, Sean Crawford, Sarah Saliba, Karen Jardine, Jian Xuan, Meredith Evans, Mary-Ellen Harper, and Michael W. McBurney PLoS ONE. 2008; 3(3): e1759. Published online 2008 March 12. doi: 10.1371/journal.pone.0001759.PMCID: PMC2258149 Origins of Spatial Working Memory Deficits in Schizophrenia: An Event-Related fMRI and Near-Infrared Spectroscopy Study Junghee Lee, Bradley S. Folley, John Gore, and Sohee Park PLoS ONE. 2008; 3(3): e1760. Published online 2008 March 12. doi: 10.1371/journal.pone.0001760.PMCID: PMC2257999 The Hippo Pathway Promotes Notch Signaling in Regulation of Cell Differentiation, Proliferation, and Oocyte Polarity Jianzhong Yu, John Poulton, Yi-Chun Huang, and Wu-Min Deng PLoS ONE. 2008; 3(3): e1761. Published online 2008 March 12. doi: 10.1371/journal.pone.0001761.PMCID: PMC2258146 L-Type Ca2+ Channel Function Is Linked to Dystrophin Expression in Mammalian Muscle Oliver Friedrich, Frederic von Wegner, Jeffrey S. Chamberlain, Rainer H. A. Fink, and Petra Rohrbach PLoS ONE. 2008; 3(3): e1762. Published online 2008 March 12. doi: 10.1371/journal.pone.0001762.PMCID: PMC2408559 Hsp110 Chaperones Regulate Prion Formation and Propagation in S. cerevisiae by Two Discrete Activities Heather Sadlish, Heike Rampelt, James Shorter, Renee D. Wegrzyn, Claes Andréasson, Susan Lindquist, and Bernd Bukau PLoS ONE. 2008; 3(3): e1763. Published online 2008 March 12. doi: 10.1371/journal.pone.0001763.PMCID: PMC2258148 The Phylogeny of the Four Pan-American MtDNA Haplogroups: Implications for Evolutionary and Disease Studies Alessandro Achilli, Ugo A. Perego, Claudio M. Bravi, Michael D. Coble, Qing-Peng Kong, Scott R. Woodward, Antonio Salas, Antonio Torroni, and Hans-Jürgen Bandelt PLoS ONE. 2008; 3(3): e1764. Published online 2008 March 12. doi: 10.1371/journal.pone.0001764.PMCID: PMC2258150 Fetuin-A Induces Cytokine Expression and Suppresses Adiponectin Production Anita M. Hennige, Harald Staiger, Corinna Wicke, Fausto Machicao, Andreas Fritsche, Hans-Ulrich Häring, and Norbert Stefan PLoS ONE. 2008; 3(3): e1765. Published online 2008 March 12. doi: 10.1371/journal.pone.0001765.PMCID: PMC2258416 Sub-Nucleocapsid Nanoparticles: A Nasal Vaccine against Respiratory Syncytial Virus Xavier Roux, Catherine Dubuquoy, Guillaume Durand, Thi-Lan Tran-Tolla, Nathalie Castagné, Julie Bernard, Agnès Petit-Camurdan, Jean-François Eléouët, and Sabine Riffault PLoS ONE. 2008; 3(3): e1766. Published online 2008 March 12. doi: 10.1371/journal.pone.0001766.PMCID: PMC2262139 Prospects for Malaria Eradication in Sub-Saharan Africa Ricardo Águas, Lisa J. White, Robert W. Snow, and M. Gabriela M. Gomes PLoS ONE. 2008; 3(3): e1767. Published online 2008 March 12. doi: 10.1371/journal.pone.0001767.PMCID: PMC2262141 Molecular Mapping of Movement-Associated Areas in the Avian Brain: A Motor Theory for Vocal Learning Origin Gesa Feenders, Miriam Liedvogel, Miriam Rivas, Manuela Zapka, Haruhito Horita, Erina Hara, Kazuhiro Wada, Henrik Mouritsen, and Erich D. Jarvis PLoS ONE. 2008; 3(3): e1768. Published online 2008 March 12. doi: 10.1371/journal.pone.0001768.PMCID: PMC2258151 Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents Sylvane Desrivières, Kristina Krause, Anne Dyer, Josef Frank, Dorothea Blomeyer, Mark Lathrop, Karl Mann, Tobias Banaschewski, Manfred Laucht, and Gunter Schumann PLoS ONE. 2008; 3(3): e1769. Published online 2008 March 12. doi: 10.1371/journal.pone.0001769.PMCID: PMC2262154 A Novel Non-Lens βγ−Crystallin and Trefoil Factor Complex from Amphibian Skin and Its Functional Implications Shu-Bai Liu, Ying-Ying He, Yun Zhang, Wen-Hui Lee, Jin-Qiao Qian, Ren Lai, and Yang Jin PLoS ONE. 2008; 3(3): e1770. Published online 2008 March 12. doi: 10.1371/journal.pone.0001770.PMCID: PMC2262142 Positive Feedback and Noise Activate the Stringent Response Regulator Rel in Mycobacteria Kamakshi Sureka, Bhaswar Ghosh, Arunava Dasgupta, Joyoti Basu, Manikuntala Kundu, and Indrani Bose PLoS ONE. 2008; 3(3): e1771. Published online 2008 March 12. doi: 10.1371/journal.pone.0001771.PMCID: PMC2258413 Clinical and Microbiological Features of HIV-Associated Tuberculous Meningitis in Vietnamese Adults M. Estee Torok, Tran Thi Hong Chau, Pham Phuong Mai, Nguyen Duy Phong, Nguyen Thi Dung, Ly Van Chuong, Sue J. Lee, M. Caws, Menno D. de Jong, Tran Tinh Hien, and Jeremy J. Farrar PLoS ONE. 2008; 3(3): e1772. Published online 2008 March 19. doi: 10.1371/journal.pone.0001772.PMCID: PMC2262136 A Novel Campylobacter jejuni Sequence Type from a Culture-Negative Patient in The Gambia Gerard A. J. Morris, Usman N. Ikumapayi, Martin Antonio, Stephen R. C. Howie, and Richard A. Adegbola PLoS ONE. 2008; 3(3): e1773. Published online 2008 March 12. doi: 10.1371/journal.pone.0001773.PMCID: PMC2258414 Circulating Matrix Metalloproteinase-9 Is Associated with Cardiovascular Risk Factors in a Middle-Aged Normal Population Peter Garvin, Lennart Nilsson, John Carstensen, Lena Jonasson, and Margareta Kristenson PLoS ONE. 2008; 3(3): e1774. Published online 2008 March 12. doi: 10.1371/journal.pone.0001774.PMCID: PMC2258002 Haptic Guidance Improves the Visuo-Manual Tracking of Trajectories Jérémy Bluteau, Sabine Coquillart, Yohan Payan, and Edouard Gentaz PLoS ONE. 2008; 3(3): e1775. Published online 2008 March 12. doi: 10.1371/journal.pone.0001775.PMCID: PMC2258003 The Anti-Proliferative Effects of the CHFR Depend on the Forkhead Associated Domain, but not E3 Ligase Activity Mediated by Ring Finger Domain Tomokazu Fukuda, Yasuyuki Kondo, and Hitoshi Nakagama PLoS ONE. 2008; 3(3): e1776. Published online 2008 March 12. doi: 10.1371/journal.pone.0001776.PMCID: PMC2258000 Human Skeletal Muscle Mitochondrial Uncoupling Is Associated with Cold Induced Adaptive Thermogenesis Sander L. J. Wijers, Patrick Schrauwen, Wim H. M. Saris, and Wouter D. van Marken Lichtenbelt PLoS ONE. 2008; 3(3): e1777. Published online 2008 March 12. doi: 10.1371/journal.pone.0001777.PMCID: PMC2258415 Metaproteomics Provides Functional Insight into Activated Sludge Wastewater Treatment Paul Wilmes, Margaret Wexler, and Philip L. Bond PLoS ONE. 2008; 3(3): e1778. Published online 2008 March 12. doi: 10.1371/journal.pone.0001778.PMCID: PMC2289847 Open-Label Comparative Clinical Study of Chlorproguanil−Dapsone Fixed Dose Combination (Lapdap™) Alone or with Three Different Doses of Artesunate for Uncomplicated Plasmodium falciparum Malaria Daniel G. Wootton, Hyginus Opara, Giancarlo A. Biagini, Maxwell K. Kanjala, Stephan Duparc, Paula L. Kirby, Mary Woessner, Colin Neate, Maggie Nyirenda, Hannah Blencowe, Queen Dube-Mbeye, Thomas Kanyok, Stephen Ward, Malcolm Molyneux, Sam Dunyo, and Peter A. Winstanley PLoS ONE. 2008; 3(3): e1779. Published online 2008 March 5. doi: 10.1371/journal.pone.0001779.PMCID: PMC2258152 Small-Bodied Humans from Palau, Micronesia Lee R. Berger, Steven E. Churchill, Bonita De Klerk, and Rhonda L. Quinn PLoS ONE. 2008; 3(3): e1780. Published online 2008 March 12. doi: 10.1371/journal.pone.0001780.PMCID: PMC2268239 Conservation Patterns of HIV-1 RT Connection and RNase H Domains: Identification of New Mutations in NRTI-Treated Patients André F. A. Santos, Renan B. Lengruber, Esmeralda A. Soares, Abhay Jere, Eduardo Sprinz, Ana M. B. Martinez, Jussara Silveira, Fernando S. Sion, Vinay K. Pathak, and Marcelo A. Soares PLoS ONE. 2008; 3(3): e1781. Published online 2008 March 12. doi: 10.1371/journal.pone.0001781.PMCID: PMC2262134 Topological Analysis of MAPK Cascade for Kinetic ErbB Signaling Takashi Nakakuki, Noriko Yumoto, Takashi Naka, Mikako Shirouzu, Shigeyuki Yokoyama, and Mariko Hatakeyama PLoS ONE. 2008; 3(3): e1782. Published online 2008 March 12. doi: 10.1371/journal.pone.0001782.PMCID: PMC2262155 PAX4 Enhances Beta-Cell Differentiation of Human Embryonic Stem Cells Chee Gee Liew, Nadia N. Shah, Sarah J. Briston, Ruth M. Shepherd, Cheen Peen Khoo, Mark J. Dunne, Harry D. Moore, Karen E. Cosgrove, and Peter W. Andrews PLoS ONE. 2008; 3(3): e1783. Published online 2008 March 12. doi: 10.1371/journal.pone.0001783.PMCID: PMC2262135 Decreased Expression of Sprouty2 in the Dorsolateral Prefrontal Cortex in Schizophrenia and Bipolar Disorder: A Correlation with BDNF Expression Anilkumar Pillai PLoS ONE. 2008; 3(3): e1784. Published online 2008 March 12. doi: 10.1371/journal.pone.0001784.PMCID: PMC2262156 Ovulation Order Mediates a Trade-Off between Pre-Hatching and Post-Hatching Viability in an Altricial Bird Keith W. Sockman PLoS ONE. 2008; 3(3): e1785. Published online 2008 March 12. doi: 10.1371/journal.pone.0001785.PMCID: PMC2262150 A Naturally Occurring Plant Cysteine Protease Possesses Remarkable Toxicity against Insect Pests and Synergizes Bacillus thuringiensis Toxin Srinidi Mohan, Peter W. K. Ma, W. Paul Williams, and Dawn S. Luthe PLoS ONE. 2008; 3(3): e1786. Published online 2008 March 12. doi: 10.1371/journal.pone.0001786.PMCID: PMC2262944 Rural-Urban Differences in Maternal Responses to Childhood Fever in South East Nigeria Benjamin S. C. Uzochukwu, Emmanuel O. Onwujekwe, Chima A. Onoka, and Maduka D. Ughasoro PLoS ONE. 2008; 3(3): e1788. Published online 2008 March 12. doi: 10.1371/journal.pone.0001788.PMCID: PMC2258001 Cardiomyocyte Formation by Skeletal Muscle-Derived Multi-Myogenic Stem Cells after Transplantation into Infarcted Myocardium Tetsuro Tamaki, Akira Akatsuka, Yoshinori Okada, Yoshiyasu Uchiyama, Kayoko Tono, Mika Wada, Akio Hoshi, Hideki Iwaguro, Hiroto Iwasaki, Akira Oyamada, and Takayuki Asahara PLoS ONE. 2008; 3(3): e1789. Published online 2008 March 12. doi: 10.1371/journal.pone.0001789.PMCID: PMC2262151 Mitigation Measures for Pandemic Influenza in Italy: An Individual Based Model Considering Different Scenarios Marta Luisa Ciofi degli Atti, Stefano Merler, Caterina Rizzo, Marco Ajelli, Marco Massari, Piero Manfredi, Cesare Furlanello, Gianpaolo Scalia Tomba, and Mimmo Iannelli PLoS ONE. 2008; 3(3): e1790. Published online 2008 March 12. doi: 10.1371/journal.pone.0001790.PMCID: PMC2258437 Transcriptomic Analyses Reveal Novel Genes with Sexually Dimorphic Expression in the Zebrafish Gonad and Brain Rajini Sreenivasan, Minnie Cai, Richard Bartfai, Xingang Wang, Alan Christoffels, and Laszlo Orban PLoS ONE. 2008; 3(3): e1791. Published online 2008 March 12. doi: 10.1371/journal.pone.0001791.PMCID: PMC2262149 Infection of Semen-Producing Organs by SIV during the Acute and Chronic Stages of the Disease Anna Le Tortorec, Roger Le Grand, Hélène Denis, Anne-Pascale Satie, Karim Mannioui, Pierre Roques, Anne Maillard, Sylvanne Daniels, Bernard Jégou, and Nathalie Dejucq-Rainsford PLoS ONE. 2008; 3(3): e1792. Published online 2008 March 12. doi: 10.1371/journal.pone.0001792.PMCID: PMC2268241 Attainment of Brown Adipocyte Features in White Adipocytes of Hormone-Sensitive Lipase Null Mice Kristoffer Ström, Ola Hansson, Stéphanie Lucas, Pernilla Nevsten, Céline Fernandez, Cecilia Klint, Sofia Movérare-Skrtic, Frank Sundler, Claes Ohlsson, and Cecilia Holm PLoS ONE. 2008; 3(3): e1793. Published online 2008 March 12. doi: 10.1371/journal.pone.0001793.PMCID: PMC2258419 Modulation of Brain Resting-State Networks by Sad Mood Induction Ben J. Harrison, Jesus Pujol, Hector Ortiz, Alex Fornito, Christos Pantelis, and Murat Yücel PLoS ONE. 2008; 3(3): e1794. Published online 2008 March 19. doi: 10.1371/journal.pone.0001794.PMCID: PMC2263138 The Grasping Side of Odours Federico Tubaldi, Caterina Ansuini, Roberto Tirindelli, and Umberto Castiello PLoS ONE. 2008; 3(3): e1795. Published online 2008 March 19. doi: 10.1371/journal.pone.0001795.PMCID: PMC2266792 Characterization and Subcellular Targeting of GCaMP-Type Genetically-Encoded Calcium Indicators Tianyi Mao, Daniel H. O'Connor, Volker Scheuss, Junichi Nakai, and Karel Svoboda PLoS ONE. 2008; 3(3): e1796. Published online 2008 March 19. doi: 10.1371/journal.pone.0001796.PMCID: PMC2262942 The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System Blerina Kola, Imre Farkas, Mirjam Christ-Crain, Gábor Wittmann, Francesca Lolli, Faisal Amin, Judith Harvey-White, Zsolt Liposits, George Kunos, Ashley B. Grossman, Csaba Fekete, and Márta Korbonits PLoS ONE. 2008; 3(3): e1797. Published online 2008 March 12. doi: 10.1371/journal.pone.0001797.PMCID: PMC2258435 Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo Jonghwan Kim, Ji-hoon Lee, and Vishwanath R. Iyer PLoS ONE. 2008; 3(3): e1798. Published online 2008 March 12. doi: 10.1371/journal.pone.0001798.PMCID: PMC2258436 Trade-Offs between the Metabolic Rate and Population Density of Plants Jian-Ming Deng, Tao Li, Gen-Xuan Wang, Jing Liu, Ze-Long Yu, Chang-Ming Zhao, Ming-Fei Ji, Qiang Zhang, and Jian-quan Liu PLoS ONE. 2008; 3(3): e1799. Published online 2008 March 19. doi: 10.1371/journal.pone.0001799.PMCID: PMC2265546 Klebsiella pneumoniae Multiresistance Plasmid pMET1: Similarity with the Yersinia pestis Plasmid pCRY and Integrative Conjugative Elements Alfonso J. C. Soler Bistué, Daniel Birshan, Andrew P. Tomaras, Manisha Dandekar, Tung Tran, Jason Newmark, Duyen Bui, Nisha Gupta, Keziah Hernandez, Renee Sarno, Angeles Zorreguieta, Luis A. Actis, and Marcelo E. Tolmasky PLoS ONE. 2008; 3(3): e1800. Published online 2008 March 19. doi: 10.1371/journal.pone.0001800.PMCID: PMC2262945 Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content Fiona Robinson, Richard J. Jackson, and Christopher W. J. Smith PLoS ONE. 2008; 3(3): e1801. Published online 2008 March 12. doi: 10.1371/journal.pone.0001801.PMCID: PMC2258417 Validity of the Common Cold Questionnaire (CCQ) in Asthma Exacerbations Heather Powell, Joanne Smart, Lisa G. Wood, Terry Grissell, Darren R. Shafren, Michael J. Hensley, and Peter G. Gibson PLoS ONE. 2008; 3(3): e1802. Published online 2008 March 19. doi: 10.1371/journal.pone.0001802.PMCID: PMC2266793 Integrative Genome-Wide Expression Analysis Bears Evidence of Estrogen Receptor-Independent Transcription in Heregulin-Stimulated MCF-7 Cells Takeshi Nagashima, Takahiro Suzuki, Shinji Kondo, Yoko Kuroki, Kaoru Takahashi, Kaori Ide, Noriko Yumoto, Aki Hasegawa, Tetsuro Toyoda, Toshio Kojima, Akihiko Konagaya, Harukazu Suzuki, Yoshihide Hayashizaki, Yoshiyuki Sakaki, and Mariko Hatakeyama PLoS ONE. 2008; 3(3): e1803. Published online 2008 March 19. doi: 10.1371/journal.pone.0001803.PMCID: PMC2266794 Awareness and Use of Benzodiazepines in Healthy Volunteers and Ambulatory Patients Visiting a Tertiary Care Hospital: A Cross Sectional Survey Mustafa Raoof, Haq Nawaz, Rabeeya Nusrat, Aqueel Hussain Pabaney, Ali Raza Randhawa, Rabeea Rehman, Nida Butool Rizvi, and Haider Naqvi PLoS ONE. 2008; 3(3): e1804. Published online 2008 March 19. doi: 10.1371/journal.pone.0001804.PMCID: PMC2265543 Comparative Analysis of Acinetobacters: Three Genomes for Three Lifestyles David Vallenet, Patrice Nordmann, Valérie Barbe, Laurent Poirel, Sophie Mangenot, Elodie Bataille, Carole Dossat, Shahinaz Gas, Annett Kreimeyer, Patricia Lenoble, Sophie Oztas, Julie Poulain, Béatrice Segurens, Catherine Robert, Chantal Abergel, Jean-Michel Claverie, Didier Raoult, Claudine Médigue, Jean Weissenbach, and Stéphane Cruveiller PLoS ONE. 2008; 3(3): e1805. Published online 2008 March 19. doi: 10.1371/journal.pone.0001805.PMCID: PMC2265553 Estimation of Relevant Variables on High-Dimensional Biological Patterns Using Iterated Weighted Kernel Functions Sergio Rojas-Galeano, Emily Hsieh, Dan Agranoff, Sanjeev Krishna, and Delmiro Fernandez-Reyes PLoS ONE. 2008; 3(3): e1806. Published online 2008 March 26. doi: 10.1371/journal.pone.0001806.PMCID: PMC2396875 Association of the Estrogen Receptor 1 (ESR1) Gene with Body Height in Adult Males from Two Swedish Population Cohorts Andreas Dahlgren, Per Lundmark, Tomas Axelsson, Lars Lind, and Ann-Christine Syvänen PLoS ONE. 2008; 3(3): e1807. Published online 2008 March 19. doi: 10.1371/journal.pone.0001807.PMCID: PMC2265544 A Gamma-Herpesvirus Glycoprotein Complex Manipulates Actin to Promote Viral Spread Michael B. Gill, Rachel Edgar, Janet S. May, and Philip G. Stevenson PLoS ONE. 2008; 3(3): e1808. Published online 2008 March 19. doi: 10.1371/journal.pone.0001808.PMCID: PMC2262946 Anti-Tuberculosis Therapy-Induced Hepatotoxicity among Ethiopian HIV-Positive and Negative Patients Getnet Yimer, Getachew Aderaye, Wondwossen Amogne, Eyasu Makonnen, Eleni Aklillu, Lars Lindquist, Lawrence Yamuah, Beniyam Feleke, and Abraham Aseffa PLoS ONE. 2008; 3(3): e1809. Published online 2008 March 19. doi: 10.1371/journal.pone.0001809.PMCID: PMC2265547 High Genetic Stability of Dengue Virus Propagated in MRC-5 Cells as Compared to the Virus Propagated in Vero Cells Chia-Chyi Liu, Shiang-Chi Lee, Michael Butler, and Suh-Chin Wu PLoS ONE. 2008; 3(3): e1810. Published online 2008 March 19. doi: 10.1371/journal.pone.0001810.PMCID: PMC2265545 Cellular Responses in Sea Fan Corals: Granular Amoebocytes React to Pathogen and Climate Stressors Laura D. Mydlarz, Sally F. Holthouse, Esther C. Peters, and C. Drew Harvell PLoS ONE. 2008; 3(3): e1811. Published online 2008 March 26. doi: 10.1371/journal.pone.0001811.PMCID: PMC2267492 Clinical Severity of Clostridium difficile PCR Ribotype 027: A Case-Case Study Oliver W. Morgan, Boaventura Rodrigues, Tony Elston, Neville Q. Verlander, Derek F. J. Brown, Jonathan Brazier, and Mark Reacher PLoS ONE. 2008; 3(3): e1812. Published online 2008 March 19. doi: 10.1371/journal.pone.0001812.PMCID: PMC2265541 The Role of Thioredoxin Reductases in Brain Development Jonna Soerensen, Cemile Jakupoglu, Heike Beck, Heidi Förster, Jörg Schmidt, Wolfgang Schmahl, Ulrich Schweizer, Marcus Conrad, and Markus Brielmeier PLoS ONE. 2008; 3(3): e1813. Published online 2008 March 19. doi: 10.1371/journal.pone.0001813.PMCID: PMC2263137 Anchor Side Chains of Short Peptide Fragments Trigger Ligand-Exchange of Class II MHC Molecules Shashank Gupta, Sabine Höpner, Bernd Rupp, Sebastian Günther, Katharina Dickhaut, Noopur Agarwal, M. Cristina Cardoso, Ronald Kühne, Karl-Heinz Wiesmüller, Günther Jung, Kirsten Falk, and Olaf Rötzschke PLoS ONE. 2008; 3(3): e1814. Published online 2008 March 19. doi: 10.1371/journal.pone.0001814.PMCID: PMC2265549 The Assembly of the Plasmodial PLP Synthase Complex Follows a Defined Course Ingrid B. Müller, Julia Knöckel, Matthew R. Groves, Rositsa Jordanova, Steven E. Ealick, Rolf D. Walter, and Carsten Wrenger PLoS ONE. 2008; 3(3): e1815. Published online 2008 March 19. doi: 10.1371/journal.pone.0001815.PMCID: PMC2266796 Multiple Oncogenic Pathway Signatures Show Coordinate Expression Patterns in Human Prostate Tumors Chad J. Creighton PLoS ONE. 2008; 3(3): e1816. Published online 2008 March 19. doi: 10.1371/journal.pone.0001816.PMCID: PMC2263127 Evidence against a Human Cell-Specific Role for LRP6 in Anthrax Toxin Entry Patricia L. Ryan and John A. T. Young PLoS ONE. 2008; 3(3): e1817. Published online 2008 March 19. doi: 10.1371/journal.pone.0001817.PMCID: PMC2263128 A Built-In Strategy for Containment of Transgenic Plants: Creation of Selectively Terminable Transgenic Rice Chaoyang Lin, Jun Fang, Xiaoli Xu, Te Zhao, Jiaan Cheng, Juming Tu, Gongyin Ye, and Zhicheng Shen PLoS ONE. 2008; 3(3): e1818. Published online 2008 March 19. doi: 10.1371/journal.pone.0001818.PMCID: PMC2262152 Catechol-O-Methyltransferase Gene Polymorphism Is Associated with Skeletal Muscle Properties in Older Women Alone and Together with Physical Activity Paula H. A. Ronkainen, Eija Pöllänen, Timo Törmäkangas, Kristina Tiainen, Markku Koskenvuo, Jaakko Kaprio, Taina Rantanen, Sarianna Sipilä, and Vuokko Kovanen PLoS ONE. 2008; 3(3): e1819. Published online 2008 March 19. doi: 10.1371/journal.pone.0001819.PMCID: PMC2265555 Probabilistic Inference of Transcription Factor Binding from Multiple Data Sources Harri Lähdesmäki, Alistair G. Rust, and Ilya Shmulevich PLoS ONE. 2008; 3(3): e1820. Published online 2008 March 26. doi: 10.1371/journal.pone.0001820.PMCID: PMC2268002 Identification of Direct Target Genes Using Joint Sequence and Expression Likelihood with Application to DAF-16 Ron X. Yu, Jie Liu, Nick True, and Wei Wang PLoS ONE. 2008; 3(3): e1821. Published online 2008 March 19. doi: 10.1371/journal.pone.0001821.PMCID: PMC2266795 Song Diversity Predicts the Viability of Fragmented Bird Populations Paola Laiolo, Matthias Vögeli, David Serrano, and José L. Tella PLoS ONE. 2008; 3(3): e1822. Published online 2008 March 19. doi: 10.1371/journal.pone.0001822.PMCID: PMC2266806 A Dual-Color Fluorescence-Based Platform to Identify Selective Inhibitors of Akt Signaling Aranzazú Rosado, Fabian Zanella, Beatriz Garcia, Amancio Carnero, and Wolfgang Link PLoS ONE. 2008; 3(3): e1823. Published online 2008 March 19. doi: 10.1371/journal.pone.0001823.PMCID: PMC2267216 Application of In Vivo Induced Antigen Technology (IVIAT) to Bacillus anthracis Sean M. Rollins, Amanda Peppercorn, John S. Young, Melissa Drysdale, Andrea Baresch, Margaret V. Bikowski, David A. Ashford, Conrad P. Quinn, Martin Handfield, Jeffrey D. Hillman, C. Rick Lyons, Theresa M. Koehler, Stephen B. Calderwood, and Edward T. Ryan PLoS ONE. 2008; 3(3): e1824. Published online 2008 March 19. doi: 10.1371/journal.pone.0001824.PMCID: PMC2265799 Detailed Enzyme Kinetics in Terms of Biochemical Species: Study of Citrate Synthase Daniel A. Beard, Kalyan C. Vinnakota, and Fan Wu PLoS ONE. 2008; 3(3): e1825. Published online 2008 March 19. doi: 10.1371/journal.pone.0001825.PMCID: PMC2266798 CD44v4 Is a Major E-Selectin Ligand that Mediates Breast Cancer Cell Transendothelial Migration Ke Zen, Dan-Qing Liu, Ya-Lan Guo, Chen Wang, Jun Shan, Ming Fang, Chen-Yu Zhang, and Yuan Liu PLoS ONE. 2008; 3(3): e1826. Published online 2008 March 19. doi: 10.1371/journal.pone.0001826.PMCID: PMC2265551 Modulation of Drosophila Retinal Epithelial Integrity by the Adhesion Proteins Capricious and Tartan Yanlan Mao, Martin Kerr, and Matthew Freeman PLoS ONE. 2008; 3(3): e1827. Published online 2008 March 19. doi: 10.1371/journal.pone.0001827.PMCID: PMC2265552 A Mouse Model of Pulmonary Metastasis from Spontaneous Osteosarcoma Monitored In Vivo by Luciferase Imaging Silvia Miretti, Ilaria Roato, Riccardo Taulli, Carola Ponzetto, Michele Cilli, Martina Olivero, Maria Flavia Di Renzo, Laura Godio, Adriana Albini, Paolo Buracco, and Riccardo Ferracini PLoS ONE. 2008; 3(3): e1828. Published online 2008 March 19. doi: 10.1371/journal.pone.0001828.PMCID: PMC2265554 Highly Specific Gene Silencing by Artificial miRNAs in Rice Norman Warthmann, Hao Chen, Stephan Ossowski, Detlef Weigel, and Philippe Hervé PLoS ONE. 2008; 3(3): e1829. Published online 2008 March 19. doi: 10.1371/journal.pone.0001829.PMCID: PMC2262943 Association of a Bovine Prion Gene Haplotype with Atypical BSE Michael L. Clawson, Juergen A. Richt, Thierry Baron, Anne-Gaëlle Biacabe, Stefanie Czub, Michael P. Heaton, Timothy P. L. Smith, and William W. Laegreid PLoS ONE. 2008; 3(3): e1830. Published online 2008 March 19. doi: 10.1371/journal.pone.0001830.PMCID: PMC2263129 Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire Sune Frankild, Rob J. de Boer, Ole Lund, Morten Nielsen, and Can Kesmir PLoS ONE. 2008; 3(3): e1831. Published online 2008 March 19. doi: 10.1371/journal.pone.0001831.PMCID: PMC2263130 Electrical Brain Responses in Language-Impaired Children Reveal Grammar-Specific Deficits Elisabeth Fonteneau and Heather K. J. van der Lely PLoS ONE. 2008; 3(3): e1832. Published online 2008 March 12. doi: 10.1371/journal.pone.0001832.PMCID: PMC2268250 Nitric Oxide Antagonizes the Acid Tolerance Response that Protects Salmonella against Innate Gastric Defenses Travis J. Bourret, Steffen Porwollik, Michael McClelland, Rui Zhao, Todd Greco, Harry Ischiropoulos, and Andrés Vázquez-Torres PLoS ONE. 2008; 3(3): e1833. Published online 2008 March 19. doi: 10.1371/journal.pone.0001833.PMCID: PMC2266805 Structural Elements Regulating Amyloidogenesis: A Cholinesterase Model System Létitia Jean, Chiu Fan Lee, Michael Shaw, and David J. Vaux PLoS ONE. 2008; 3(3): e1834. Published online 2008 March 19. doi: 10.1371/journal.pone.0001834.PMCID: PMC2265548 Ancient DNA Elucidates the Controversy about the Flightless Island Hens (Gallinula sp.) of Tristan da Cunha Dick S. J. Groenenberg, Albert J. Beintema, René W. R. J. Dekker, and Edmund Gittenberger PLoS ONE. 2008; 3(3): e1835. Published online 2008 March 19. doi: 10.1371/journal.pone.0001835.PMCID: PMC2266797 Improving Phrap-Based Assembly of the Rat Using “Reliable” Overlaps Michael Roberts, Aleksey V. Zimin, Wayne Hayes, Brian R. Hunt, Cevat Ustun, James R. White, Paul Havlak, and James Yorke PLoS ONE. 2008; 3(3): e1836. Published online 2008 March 19. doi: 10.1371/journal.pone.0001836.PMCID: PMC2266800 Hippocampus Shape Analysis and Late-Life Depression Zheen Zhao, Warren D. Taylor, Martin Styner, David C. Steffens, K. Ranga R. Krishnan, and James R. MacFall PLoS ONE. 2008; 3(3): e1837. Published online 2008 March 19. doi: 10.1371/journal.pone.0001837.PMCID: PMC2265542 A Role for Gene Duplication and Natural Variation of Gene Expression in the Evolution of Metabolism Daniel J. Kliebenstein PLoS ONE. 2008; 3(3): e1838. Published online 2008 March 19. doi: 10.1371/journal.pone.0001838.PMCID: PMC2263126 Population-Wide Emergence of Antiviral Resistance during Pandemic Influenza Seyed M. Moghadas, Christopher S. Bowman, Gergely Röst, and Jianhong Wu PLoS ONE. 2008; 3(3): e1839. Published online 2008 March 19. doi: 10.1371/journal.pone.0001839.PMCID: PMC2266801 Seeing ‘Where’ through the Ears: Effects of Learning-by-Doing and Long-Term Sensory Deprivation on Localization Based on Image-to-Sound Substitution Michael J. Proulx, Petra Stoerig, Eva Ludowig, and Inna Knoll PLoS ONE. 2008; 3(3): e1840. Published online 2008 March 26. doi: 10.1371/journal.pone.0001840.PMCID: PMC2267489 Morphological Evolution of Spiders Predicted by Pendulum Mechanics Jordi Moya-Laraño, Dejan Vinković, Eva De Mas, Guadalupe Corcobado, and Eulalia Moreno PLoS ONE. 2008; 3(3): e1841. Published online 2008 March 26. doi: 10.1371/journal.pone.0001841.PMCID: PMC2266996 Stochastic Resonance Reveals “Pilot Light” Expression in Mammalian Genes Andrey Ptitsyn PLoS ONE. 2008; 3(3): e1842. Published online 2008 March 26. doi: 10.1371/journal.pone.0001842.PMCID: PMC2266998 Mouse Ribosomal RNA Genes Contain Multiple Differentially Regulated Variants Hung Tseng, Weichin Chou, Junwen Wang, Xiaohong Zhang, Shengliang Zhang, and Richard M. Schultz PLoS ONE. 2008; 3(3): e1843. Published online 2008 March 26. doi: 10.1371/journal.pone.0001843.PMCID: PMC2266999 Dynamics of Co-Transcriptional Pre-mRNA Folding Influences the Induction of Dystrophin Exon Skipping by Antisense Oligonucleotides Keng Boon Wee, Zacharias Aloysius Dwi Pramono, Jian Li Wang, Karl F. MacDorman, Poh San Lai, and Woon Chee Yee PLoS ONE. 2008; 3(3): e1844. Published online 2008 March 26. doi: 10.1371/journal.pone.0001844.PMCID: PMC2267000 Isotope Analysis Reveals Foraging Area Dichotomy for Atlantic Leatherback Turtles Stéphane Caut, Elodie Guirlet, Elena Angulo, Krishna Das, and Marc Girondot PLoS ONE. 2008; 3(3): e1845. Published online 2008 March 26. doi: 10.1371/journal.pone.0001845.PMCID: PMC2267998 Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster Matthias Vömel and Christian Wegener PLoS ONE. 2008; 3(3): e1848. Published online 2008 March 26. doi: 10.1371/journal.pone.0001848.PMCID: PMC2268740 Distinct Methylation Changes at the IGF2-H19 Locus in Congenital Growth Disorders and Cancer Adele Murrell, Yoko Ito, Gaetano Verde, Joanna Huddleston, Kathryn Woodfine, Margherita Cirillo Silengo, Filippo Spreafico, Daniela Perotti, Agostina De Crescenzo, Angela Sparago, Flavia Cerrato, and Andrea Riccio PLoS ONE. 2008; 3(3): e1849. Published online 2008 March 26. doi: 10.1371/journal.pone.0001849.PMCID: PMC2268001 T-Cell Assays for Tuberculosis Infection: Deriving Cut-Offs for Conversions Using Reproducibility Data Anandharaman Veerapathran, Rajnish Joshi, Kalyan Goswami, Sandeep Dogra, Erica E. M. Moodie, M. V. R. Reddy, Shriprakash Kalantri, Kevin Schwartzman, Marcel A. Behr, Dick Menzies, and Madhukar Pai PLoS ONE. 2008; 3(3): e1850. Published online 2008 March 26. doi: 10.1371/journal.pone.0001850.PMCID: PMC2266993 Notch Signaling Regulates Bile Duct Morphogenesis in Mice Julie Lozier, Brent McCright, and Thomas Gridley PLoS ONE. 2008; 3(3): e1851. Published online 2008 March 26. doi: 10.1371/journal.pone.0001851.PMCID: PMC2266994 Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels Federica Chiara, Diego Castellaro, Oriano Marin, Valeria Petronilli, William S. Brusilow, Magdalena Juhaszova, Steven J. Sollott, Michael Forte, Paolo Bernardi, and Andrea Rasola PLoS ONE. 2008; 3(3): e1852. Published online 2008 March 19. doi: 10.1371/journal.pone.0001852.PMCID: PMC2267038 Haplotype Reconstruction Error as a Classical Misclassification Problem: Introducing Sensitivity and Specificity as Error Measures Claudia Lamina, Friedhelm Bongardt, Helmut Küchenhoff, and Iris M. Heid PLoS ONE. 2008; 3(3): e1853. Published online 2008 March 26. doi: 10.1371/journal.pone.0001853.PMCID: PMC2267219 Using Ribosomal Protein Genes as Reference: A Tale of Caution Lieven Thorrez, Katrijn Van Deun, Léon-Charles Tranchevent, Leentje Van Lommel, Kristof Engelen, Kathleen Marchal, Yves Moreau, Iven Van Mechelen, and Frans Schuit PLoS ONE. 2008; 3(3): e1854. Published online 2008 March 26. doi: 10.1371/journal.pone.0001854.PMCID: PMC2267211 Plasmodium falciparum Transcriptome Analysis Reveals Pregnancy Malaria Associated Gene Expression Nicaise Tuikue Ndam, Emmanuel Bischoff, Caroline Proux, Thomas Lavstsen, Ali Salanti, Juliette Guitard, Morten A. Nielsen, Jean-Yves Coppée, Alioune Gaye, Thor Theander, Peter H. David, and Philippe Deloron PLoS ONE. 2008; 3(3): e1855. Published online 2008 March 26. doi: 10.1371/journal.pone.0001855.PMCID: PMC2267001 Nogo-66 Promotes the Differentiation of Neural Progenitors into Astroglial Lineage Cells through mTOR-STAT3 Pathway Bin Wang, Zhifeng Xiao, Bing Chen, Jin Han, Yuan Gao, Jing Zhang, Wenxue Zhao, Xia Wang, and Jianwu Dai PLoS ONE. 2008; 3(3): e1856. Published online 2008 March 26. doi: 10.1371/journal.pone.0001856.PMCID: PMC2266802 Transepithelial Transport and Enzymatic Detoxification of Gluten in Gluten-Sensitive Rhesus Macaques Michael T. Bethune, Erin Ribka, Chaitan Khosla, and Karol Sestak PLoS ONE. 2008; 3(3): e1857. Published online 2008 March 26. doi: 10.1371/journal.pone.0001857.PMCID: PMC2267209 Australia's Oldest Marsupial Fossils and their Biogeographical Implications Robin M. D. Beck, Henk Godthelp, Vera Weisbecker, Michael Archer, and Suzanne J. Hand PLoS ONE. 2008; 3(3): e1858. Published online 2008 March 26. doi: 10.1371/journal.pone.0001858.PMCID: PMC2267999 Genomics of Signaling Crosstalk of Estrogen Receptor α in Breast Cancer Cells Peter Dudek and Didier Picard PLoS ONE. 2008; 3(3): e1859. Published online 2008 March 26. doi: 10.1371/journal.pone.0001859.PMCID: PMC2268000 Tool-Use Training in a Species of Rodent: The Emergence of an Optimal Motor Strategy and Functional Understanding Kazuo Okanoya, Naoko Tokimoto, Noriko Kumazawa, Sayaka Hihara, and Atsushi Iriki PLoS ONE. 2008; 3(3): e1860. Published online 2008 March 26. doi: 10.1371/journal.pone.0001860.PMCID: PMC2268009 Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury Matthew Siegel, Pavel Strnad, R. Edward Watts, Kihang Choi, Bana Jabri, M. Bishr Omary, and Chaitan Khosla PLoS ONE. 2008; 3(3): e1861. Published online 2008 March 26. doi: 10.1371/journal.pone.0001861.PMCID: PMC2267210 p16INK4a Translation Suppressed by miR-24 Ashish Lal, Hyeon Ho Kim, Kotb Abdelmohsen, Yuki Kuwano, Rudolf Pullmann, Jr., Subramanya Srikantan, Ramesh Subrahmanyam, Jennifer L. Martindale, Xiaoling Yang, Fariyal Ahmed, Francisco Navarro, Derek Dykxhoorn, Judy Lieberman, and Myriam Gorospe PLoS ONE. 2008; 3(3): e1864. Published online 2008 March 26. doi: 10.1371/journal.pone.0001864.PMCID: PMC2274865 The Deleted in Brachydactyly B Domain of ROR2 Is Required for Receptor Activation by Recruitment of Src Shiva Akbarzadeh, Lee M. Wheldon, Steve M. M. Sweet, Sonia Talma, Faraz Khosravi Mardakheh, and John K. Heath PLoS ONE. 2008; 3(3): e1873. Published online 2008 March 26. doi: 10.1371/journal.pone.0001873.PMCID: PMC2268744 Malaria Liver Stage Susceptibility Locus Identified on Mouse Chromosome 17 by Congenic Mapping Lígia Antunes Gonçalves, Paulo Almeida, Maria Manuel Mota, and Carlos Penha-Gonçalves PLoS ONE. 2008; 3(3): e1874. Published online 2008 March 26. doi: 10.1371/journal.pone.0001874.PMCID: PMC2267218 Differences in Muscle Protein Synthesis and Anabolic Signaling in the Postabsorptive State and in Response to Food in 65–80 Year Old Men and Women Gordon I. Smith, Philip Atherton, Dennis T. Villareal, Tiffany N. Frimel, Debbie Rankin, Michael J. Rennie, and Bettina Mittendorfer PLoS ONE. 2008; 3(3): e1875. Published online 2008 March 26. doi: 10.1371/journal.pone.0001875.PMCID: PMC2267222 Massive Autophosphorylation of the Ser/Thr-Rich Domain Controls Protein Kinase Activity of TRPM6 and TRPM7 Kristopher Clark, Jeroen Middelbeek, Nick A. Morrice, Carl G. Figdor, Edwin Lasonder, and Frank N. van Leeuwen PLoS ONE. 2008; 3(3): e1876. Published online 2008 March 26. doi: 10.1371/journal.pone.0001876.PMCID: PMC2267223 A Marked Effect of Electroconvulsive Stimulation on Behavioral Aberration of Mice with Neuron-Specific Mitochondrial DNA Defects Takaoki Kasahara, Mie Kubota, Taeko Miyauchi, Mizuho Ishiwata, and Tadafumi Kato PLoS ONE. 2008; 3(3): e1877. Published online 2008 March 26. doi: 10.1371/journal.pone.0001877.PMCID: PMC2267493 An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation Maria E. Figueroa, Mark Reimers, Reid F. Thompson, Kenny Ye, Yushan Li, Rebecca R. Selzer, Jakob Fridriksson, Elisabeth Paietta, Peter Wiernik, Roland D. Green, John M. Greally, and Ari Melnick PLoS ONE. 2008; 3(3): e1882. Published online 2008 March 26. doi: 10.1371/journal.pone.0001882.PMCID: PMC2266992 The Efficacy of Tetracyclines in Peripheral and Intracerebral Prion Infection Ada De Luigi, Laura Colombo, Luisa Diomede, Raffaella Capobianco, Michela Mangieri, Claudia Miccolo, Lucia Limido, Gianluigi Forloni, Fabrizio Tagliavini, and Mario Salmona PLoS ONE. 2008; 3(3): e1888. Published online 2008 March 26. doi: 10.1371/journal.pone.0001888.PMCID: PMC2268013 Genome-Wide Detection of Serpentine Receptor-Like Proteins in Malaria Parasites Luciana Madeira, Pedro A. F. Galante, Alexandre Budu, Mauro F. Azevedo, Bettina Malnic, and Célia R. S. Garcia PLoS ONE. 2008; 3(3): e1889. Published online 2008 March 26. doi: 10.1371/journal.pone.0001889.PMCID: PMC2268965 Contribution of Recipient-Derived Cells in Allograft Neointima Formation and the Response to Stent Implantation Xiaoli Ma, Benjamin Hibbert, Dawn White, Richard Seymour, Stewart C. Whitman, and Edward R. O'Brien PLoS ONE. 2008; 3(3): e1894. Published online 2008 March 26. doi: 10.1371/journal.pone.0001894.PMCID: PMC2267220 The Efficacy of Pharmacotherapy for Decreasing the Expansion Rate of Abdominal Aortic Aneurysms: A Systematic Review and Meta-Analysis Idris Guessous, Daniel Periard, Diane Lorenzetti, Jacques Cornuz, and William A. Ghali PLoS ONE. 2008; 3(3): e1895. Published online 2008 March 26. doi: 10.1371/journal.pone.0001895.PMCID: PMC2267254 Mapping Peptidergic Cells in Drosophila: Where DIMM Fits In Dongkook Park, Jan A. Veenstra, Jae H. Park, and Paul H. Taghert PLoS ONE. 2008; 3(3): e1896. Published online 2008 March 26. doi: 10.1371/journal.pone.0001896.PMCID: PMC2266995 Regulation of the Neural Circuitry of Emotion by Compassion Meditation: Effects of Meditative Expertise Antoine Lutz, Julie Brefczynski-Lewis, Tom Johnstone, and Richard J. Davidson PLoS ONE. 2008; 3(3): e1897. Published online 2008 March 26. doi: 10.1371/journal.pone.0001897.PMCID: PMC2267490 Host Genetic Factors and Vaccine-Induced Immunity to Hepatitis B Virus Infection Branwen J. Hennig, Katherine Fielding, John Broxholme, Mathurin Diatta, Maimuna Mendy, Catrin Moore, Andrew J. Pollard, Pura Rayco-Solon, Giorgio Sirugo, Marianne A. van der Sande, Pauline Waight, Hilton C. Whittle, Syed M. Zaman, Adrian V. Hill, and Andrew J. Hall PLoS ONE. 2008; 3(3): e1898. Published online 2008 March 26. doi: 10.1371/journal.pone.0001898.PMCID: PMC2268746 Corrections Correction: Small-Bodied Humans from Palau, Micronesia Lee R. Berger, Steven E. Churchill, Bonita De Klerk, and Rhonda L. Quinn PLoS ONE. 2008; 3(3): 10.1371/annotation/0b1a375a-ea43-4586-824f-05bc5b359d63. Published online 2008 March 19. doi: 10.1371/annotation/0b1a375a-ea43-4586-824f-05bc5b359d63.PMCID: PMC2637093 Corrects: Lee R. Berger, et al. Small-Bodied Humans from Palau, Micronesia. PLoS ONE. 2008; 3(3): e1780. Correction: Architecture of an Antagonistic Tree/Fungus Network: The Asymmetric Influence of Past Evolutionary History Corinne Vacher, Dominique Piou, and Marie-Laure Desprez-Loustau PLoS ONE. 2008; 3(3): 10.1371/annotation/c03a4beb-a3fa-4b78-8724-b3c8ce28c415. Published online 2008 March 19. doi: 10.1371/annotation/c03a4beb-a3fa-4b78-8724-b3c8ce28c415.PMCID: PMC2637094 Corrects: Corinne Vacher, et al. Architecture of an Antagonistic Tree/Fungus Network: The Asymmetric Influence of Past Evolutionary History. PLoS ONE. 2008; 3(3): e1740. |