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- Teens with Treatment-resistant Depression More Likely to Get Better with Switch to Combination Therapy
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February 26, 2008
Press Release
Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more likely to get well if they switch to another antidepressant medication and add psychotherapy rather than just switching to another antidepressant.
- Group Therapy Program Offers Meaningful Gains for People with Borderline Personality Disorder
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February 26, 2008
Science Update
A 20-week group therapy program focusing on cognitive behavioral and skills training, when used in conjunction with usual care, helped reduce symptoms of borderline personality disorder and improve overall functioning, reported NIMH-funded researchers. Their findings were published online February 15, 2008 in the American Journal of Psychiatry.
- Co-occurring Anxiety Complicates Treatment Response for Those with Major Depression
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February 25, 2008
Science Update
People with major depression accompanied by high levels of anxiety are significantly less likely to benefit from antidepressant medication than those without anxiety, according to a study based on data from the NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study.
- Genetic Variation May Influence Response to Depression Treatment
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February 20, 2008
Science Update
Variations in a gene known as TREK1 may explain some forms of treatment-resistant major depression, according to a new study analyzing genetic data.
- Team Care for Depressed Older Adults Cuts Overall Medical Costs
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February 14, 2008
Science Update
A team approach to depression treatment for older adults, already shown to be effective, is also less expensive than usual care.
- Family-centered Intervention Effectively Reduces Risky Behavior Among Hispanic Youth
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December 20, 2007
Science Update
A family-centered program that improves parent-child dynamics and family functioning is more effective at discouraging Hispanic youth from engaging in risky behavior than programs that target specific behaviors.
- Behavioral Therapy Effectively Treats Children with Social Phobia
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December 17, 2007
Science Update
A behavioral therapy designed to treat children diagnosed with social phobia helped them overcome more of their symptoms than the antidepressant fluoxetine (Prozac).
- Behavioral Program May Stabilize Stress Hormone Patterns in Foster Children
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November 30, 2007
Science Update
An intervention designed to enhance family interaction and improve foster parenting skills may benefit young foster children who had experienced extreme neglect or maltreatment in early life.
- Depressed Adolescents Respond Best to Combination Treatment
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October 1, 2007
Press Release
A combination of psychotherapy and antidepressant medication appears to be the most effective treatment for adolescents with major depressive disorder—more than medication alone or psychotherapy alone.
- Family Involvement and Focused Intervention May be Key to Helping Teens with Bulimia
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September 17, 2007
Science Update
Family-based treatment for adolescent bulimia nervosa (FBT-BN) is more effective than an individual-based therapy called supportive psychotherapy (SPT) in helping teens overcome bulimia according to an NIMH-funded study.