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Science News about Schizophrenia

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Older Medication May Be More Cost-Effective for Some Patients with Schizophrenia
December 1, 2006 • Press Release
A new study analyzing the economic implications of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) concludes that the older (first generation) antipsychotic medication perphenazine was less expensive and no less effective than the newer (second generation) medications used in the trial during initial treatment, suggesting that older antipsychotics still have a role in treating schizophrenia.
New Schizophrenia Trial: Does Method of Administering Medication Make a Difference?
September 5, 2006 • Science Update
A new clinical trial is testing whether an injection of a long-lasting antipsychotic medication every two weeks results in better adherence to treatment and better outcomes among people with schizophrenia than do oral medications taken daily.
New Factors Identified for Predicting Violence in Schizophrenia
July 18, 2006 • Science Update
A study of adults with schizophrenia showed that symptoms of losing contact with reality, such as delusions and hallucinations, increased the odds of serious violence nearly threefold.
Studies ID Molecular Accomplices of Suspect Schizophrenia Genes
May 2, 2006 • Science Update
NIMH-funded researchers have discovered how certain genes work at the molecular level to increase the risk of schizophrenia.
Studies Offer New Information About Treatment Choices for Schizophrenia — Phase 2 Results
April 1, 2006 • Science Update
A national clinical trial comparing clozapine with other new-generation antipsychotic medications for the treatment of chronic schizophrenia has shown that people who switched to clozapine from their first medication because it failed to manage symptoms adequately were twice as likely to continue treatment as patients who switched to other antipsychotic medications.
Web Forum Launched for Schizophrenia Researchers
October 28, 2005 • Press Release
Researchers trying to crack one of medicine's most perplexing unsolved mysteries can now keep abreast of late-breaking developments via the Schizophrenia Research Forum, a website launched this month with funding from the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH). Sponsored by NARSAD,
Teens with Deletion Syndrome Confirm Gene’s Role in Psychosis
October 23, 2005 • Press Release
A study in youth who are missing part of a chromosome is further implicating a suspect gene in schizophrenia.
NIMH Study To Guide Treatment Choices for Schizophrenia (Phase 1 Results)
September 19, 2005 • Press Release
A large study funded by NIH's National Institute of Mental Health (NIMH) provides, for the first time, detailed information comparing the effectiveness and side effects of five medications
Brain Scans Reveal How Gene May Boost Schizophrenia Risk
April 21, 2005 • Press Release
Clues about how a suspect version of a gene may slightly increase risk for schizophrenia are emerging from a brain imaging study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).
Stress Impairs Thinking Via Mania-Linked Enzyme
October 29, 2004 • Press Release
An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows.
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