National Toxicology Program

CASRN: 57117-31-4

Formula: C12 H3 C15 O

Synonyms/Common Names:

• PENTACHLORODIBENZOFURAN (TOXIC EQUIVALENCY FACTOR EVALUATION)
• TOXIC EQUIVALENCY FACTOR EVALUATION (2,3,4,7,8-PENTACHLORODIBENZOFURAN)

Known Uses:

ONE OF 5 DIOXIN-LIKE COMPOUNDS PLUS 2 MIXTURES BEING TESTED TO DETERMINE IF THE TOXIC EQUIVALENCY FACTORS (TEFS) FOR THESE CHEMICALS WOULD BE PREDICTIVE OF RODENT CARCINOGENICITY.

Long-Term Carcinogenicity

• 2-YEAR (Gavage)  (C96007F) Report Complete 
  • TR-525 (NTIS No. PB2007-103746)  (Peer Review 02/17/2004)
    Toxicology and Carcinogenesis Studies of 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CAS No. 57117-31-4) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
  • Rats: Sprague Dawley
  • Carcinogenesis Results
  • Female Rats Some Evidence 
  • Dose: FEMALE RATS ONLY: PeCDF -- 0, 6, 20, 44, 92, OR 200 NG/KG; 100/DOSE