National Toxicology Program

CASRN: 64742-88-7

Formula: UNKNOWN

Synonyms/Common Names:

• SOLVENT NAPTHA, PETROLEUM, MEDIUM ALIPH.

Known Uses:

PETROLEUM SOLVENT; USES INCLUDE PAINT VEHICLES; THINNING AGENT FOR PAINTS, COATINGS, AND WAXES; PRINTING INKS; ADHESIVES; SOLVENT IN LIQUID PHOTOCOPIER TONERS; SOLVENT IN DRY CLEANING; DEGREASES FOR ENGINE PARTS IN MACHINE & AUTO REPAIR SHOPS.

Nomination Background

Short-Term Toxicity

• 2-WEEK (Inhalation)  (C96001) Completed 
  • NTIS No. PB2005-103487  (Peer Review 05/22/2003)
    Citation: Toxicology and Carcinogenesis Studies of Stoddard Solvent IIC (CAS No. 64742-88-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M: 0, 188, 375, 550, 1100, OR 2200 MG/M3; 5 SEX/SPECIES/GROUP
• 13-WEEK (Inhalation)  (C96001) Completed 
  • NTIS No. PB2005-103487  (Peer Review 05/22/2003)
    Citation: Toxicology and Carcinogenesis Studies of Stoddard Solvent IIC (CAS No. 64742-88-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M: 0, 188, 375, 550, 1100, OR 2200 MG/M3; R: 20/SEX/GROUP; M: 10/SEX/GROUP

Long-Term Carcinogenicity

• 2-YEAR (Inhalation)  (C96001) Report Complete 
  • TR-519 (NTIS No. PB2005-103487)  (Peer Review 05/22/2003)
    Toxicology and Carcinogenesis Studies of Stoddard Solvent IIC (CAS No. 64742-88-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Some Evidence 
  • Female Rats No Evidence 
  • Male Mice No Evidence 
  • Female Mice Equivocal Evidence 
  • Dose: MR: 0, 188, 550, OR 1100 MG/M3; FR & M: 0, 550, 1100, OR 2200 MG/M3

Genetic Toxicology

• Micronucleus  (A45886) Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Salmonella  (A03143) Completed 
  •  Negative