National Toxicology Program

CASRN: DIETH/DIMETH

Secondary:

• 84-66-2 - Diethyl phthalate
• 131-11-3 - Dimethyl phthalate

Known Uses:

DIETHYL: CELLULOID MANUFACTURE, COSMETICS, VARNISHES, DOPES, INSECTICIDAL SOAPS, PLASTICIZER. DIMETHYL: INSECTICIDES, PLASTICIZER, SOLVENT, DYE CARRIER, ROCKET FUEL

Long-Term Carcinogenicity

• 2-YEAR (Topical Application)  (C55914) Report Complete 
  • TR-429 (NTIS No. PB96-162276)  (Peer Review 11/17/1993)
    Toxicology and Carcinogenesis Studies of Diethylphthalate (CAS No. 84-66-2) in F344/N Rats and B6C3F1 Mice (Dermal Studies) with Dermal Initiation/Promotion Study of Diethylphthalate and Dimethylphthalate (CAS No. 131-11-3) in Male Swiss (CD-1®) Mice
  • Mice: Swiss CD-1
  • Dose: 100 UL (PROMOTOR) NEAT CHEMICAL ON UNINITIATED AND DMBA INITIATED SKIN