National Toxicology Program

CASRN: 10026-24-1

Related: COBALT SULFATE

Formula: Co-O4-S.7H2-O

Synonyms/Common Names:

• COBALTOUS SULFATE
• SULFURIC ACID, COBALT(2+) SALT (1:1), HEPTAHYDRATE (8CI)(9CI)

Known Uses:

DRYING AGENT FOR VARNISHES AND INKS; COMPONENT OF ELECTROPLATING SOLUTIONS

Short-Term Toxicity

• 2-WEEK (Inhalation)  (C61530) Completed 
  • TOX-05 (NTIS No. PB91-185348)  (Peer Review 06/27/1989)
    Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1Mice (Inhalation Studies) (CAS No. 10026-24-1)
  • Mice: B6C3F1
• 3-WEEK (Inhalation)  (C61530) Completed 
  • TOX-05 (NTIS No. PB91-185348)  (Peer Review 06/27/1989)
    Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1Mice (Inhalation Studies) (CAS No. 10026-24-1)
  • Rats: F344/N
• 13-WEEK (Inhalation)  (C61530) Report Complete 
  • TOX-05 (NTIS No. PB91-185348)  (Peer Review 06/27/1989)
    Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1Mice (Inhalation Studies) (CAS No. 10026-24-1)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M:0,.3,1.0,3.0, 10.0,30.0 MG/M3

Long-Term Carcinogenicity

• 2-YEAR (Inhalation)  (C61530B) Report Complete 
  • TR-471 (NTIS No. PB99-106627)  (Peer Review 12/11/1996)
    Toxicology and Carcinogenesis Studies of Cobalt Sulfate Heptahydrate (CAS No. 10026-24-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Some Evidence 
  • Female Rats Clear Evidence 
  • Male Mice Clear Evidence 
  • Female Mice Clear Evidence 
  • Dose: R&M: 0, 0.3, 1.0, OR 3.0 MG/M3; 50/SEX/SPECIES/GROUP

Genetic Toxicology

• Salmonella  (591193) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
  •  Weakly Positive