Testing Status of Agents at NTP
Decalin
CASRN: 91-17-8
Related: TETRALIN (CAS: 119-64-2)
Formula: C10-H18
Synonyms/Common Names:
- NAPHTHALENE, DECAHYDRO- (9CI)
Known Uses:
RESEARCH CHEMICAL, SOLVENT FOR NAPHTHALENE, FATS, RESINS, OILS, IN MOTOR FUEL & LUBRICANTS.
Nomination Background
Short-Term Toxicity
- 2-WEEK (Inhalation)
(C93026) Completed
- NTIS No. PB2005-107379
(Peer Review 09/05/2002)
Citation: Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR Rats (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1; Rats: NCI Black Reiter (NBR)
- Dose: R&M: 0, 25, 50, 100, 200, OR 400 PPM; 5/SEX/SPECIES/GROUP
- NTIS No. PB2005-107379
(Peer Review 09/05/2002)
- 13-WEEK (Inhalation)
(C93026) Completed
- NTIS No. PB2005-107379
(Peer Review 09/05/2002)
Citation: Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR Rats (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 25, 50, 100, 200, OR 400 PPM R: 20/SEX/GROUP M: 10/SEX/GROUP MR: 5/GROUP RENAL TOX
- NTIS No. PB2005-107379
(Peer Review 09/05/2002)
Long-Term Carcinogenicity
- 2-YEAR (Inhalation)
(C93026) Report Complete
- TR-513 (NTIS No. PB2005-107379)
(Peer Review 09/05/2002)
Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR Rats (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Clear Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice Equivocal Evidence
- Dose: M&F MICE AND FEMALE RATS: 0, 25, 100, OR 400 PPM MALE RATS: 0, 25, 50, 100, OR 400 PPM (20 MALES); 50/SEX/SPECIES/GROUP
- TR-513 (NTIS No. PB2005-107379)
(Peer Review 09/05/2002)
Genetic Toxicology
- Micronucleus
(A40482) Completed
- Mice: B6C3F1
- Male Weakly Positive
- Female Negative
- Salmonella
(A08124) Completed
- Negative
Organ Systems Toxicity
- GD 7-14 Short-Term in vivo Repro. Tox. (Gavage)
(T0037) Completed
- NTIS No. PB83-257600
Citation: Screening of Priority Chemicals for Reproductive Hazards - F Mice: Swiss
- Dose: 2700 MG/KG BODY WEIGHT
- NTIS No. PB83-257600
Web page last updated on January 22, 2009