National Toxicology Program

CASRN: 10326-27-9

Formula: BA CL2.2H20

Known Uses:

CHEMICAL REAGENT. BOILER COMPOUNDS. PIGMENTS AND TEXTILE DYEING. (2)

Short-Term Toxicity

• 14-Day (Dosed-Water)  (C61074A) Completed 
  • NTIS No. PB94-214178
    Citation: Toxicology and Carcinogenesis Studies of Barium Chloride Dihydrate (CAS No. 10326-27-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Dosed-Water)  (C61074A) Completed 
  • NTIS No. PB94-214178
    Citation: Toxicology and Carcinogenesis Studies of Barium Chloride Dihydrate (CAS No. 10326-27-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: 0,125,4000 PPM/10 PER GROUP

Long-Term Carcinogenicity

• 2-YEAR (Dosed-Water)  (C61074B) Report Complete 
  • TR-432 (NTIS No. PB94-214178)  (Peer Review 06/22/1993)
    Toxicology and Carcinogenesis Studies of Barium Chloride Dihydrate (CAS No. 10326-27-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats No Evidence 
  • Female Rats No Evidence 
  • Male Mice No Evidence 
  • Female Mice No Evidence 
  • Dose: 0,500,1200,2500 PPM

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (384673) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Negative 
• Mouse Lymphoma  (741714) Completed 
  •  Positive 
• Salmonella  (007321) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
  •  Negative 

Organ Systems Toxicity

• Neurotoxicology Assessment (Dosed-Feed)  (NTA94032) Completed 
  • Citation: Animal Neurobehavioral Test Battery in NTP Assessment In: Advances in Neurobehavioral Toxicology: Applications in Environmental & Occupational Health (Barry L. Johnson, ED.), Lewis Publishers, Inc. pp. 403-418 (1990).
  • M/F Rats/Mice: F344/N