Testing Status of Agents at NTP
Toxaphene
CASRN: 8001-35-2
Formula: C10 H8 CL8
Synonyms/Common Names:
- CAMPHECHLOR
Known Uses:
INSECTICIDE
Nomination Background
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C00259) Completed
- NTIS No. PB292290
(Peer Review 08/31/1978)
Citation: Bioassay of Toxaphene for Possible Carcinogenicity (CAS No. 8001-35-2) - Rats: Osborne Mendel; Mice: B6C3F1
- NTIS No. PB292290
(Peer Review 08/31/1978)
- 13-Week (Dosed-Feed)
(C00259) Completed
- NTIS No. PB292290
(Peer Review 08/31/1978)
Citation: Bioassay of Toxaphene for Possible Carcinogenicity (CAS No. 8001-35-2) - Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0,160,2560 (AVG), M: 0,40,1280 (AVG) PPM/10 PER GROUP
- NTIS No. PB292290
(Peer Review 08/31/1978)
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C00259) Report Complete
- TR-037 (NTIS No. PB292290)
(Peer Review 08/31/1978)
Bioassay of Toxaphene for Possible Carcinogenicity (CAS No. 8001-35-2) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal
- Female Rats Equivocal
- Male Mice Positive
- Female Mice Positive
- Dose: MR: 0,556,1112 (AVG), FR: 0,540,1080 (AVG), M: 0,99,198 (AVG) PPM/50 PER GROUP
- TR-037 (NTIS No. PB292290)
(Peer Review 08/31/1978)
Genetic Toxicology
- Salmonella
(907413) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Positive
Web page last updated on January 22, 2009