Testing Status of Agents at NTP
Allyl glycidyl ether
CASRN: 106-92-3
Formula: C6 H10 O2
Synonyms/Common Names:
- ((2-PROPENYLOXY)METHYL)-OXIRANE (9CI)
Known Uses:
STABILIZER OF CHLORINATED COMPOUNDS, VINYL RESINS, RUBBER; RESIN INTERMEDIATE.
Short-Term Toxicity
- 14-Day (Inhalation)
(C56666) Completed
- NTIS No. PB90-260027
(Peer Review 06/27/1989)
Citation: Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CAS No. 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalation Studies) - Rats: Osborne Mendel; Mice: B6C3F1
- NTIS No. PB90-260027
(Peer Review 06/27/1989)
- 13-Week (Inhalation)
(C56666) Completed
- NTIS No. PB90-260027
(Peer Review 06/27/1989)
Citation: Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CAS No. 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalation Studies) - Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0,4,200, M: 0,1,30 PPM/10 PER GROUP
- NTIS No. PB90-260027
(Peer Review 06/27/1989)
Long-Term Carcinogenicity
- 2-YEAR (Inhalation)
(C56666) Report Complete
- TR-376 (NTIS No. PB90-260027)
(Peer Review 06/27/1989)
Toxicology and Carcinogenesis Studies of Allyl Glycidyl Ether (CAS No. 106-92-3) in Osborne-Mendel Rats and B6C3F1 Mice (Inhalation Studies) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Equivocal Evidence
- Female Rats No Evidence
- Male Mice Some Evidence
- Female Mice Equivocal Evidence
- Dose: R&M: 0,5,10 PPM/50 PER GROUP
- TR-376 (NTIS No. PB90-260027)
(Peer Review 06/27/1989)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(691488) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- Drosophila
(486088) Completed
- Citation: Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
- Sex-Linked Recessive Lethal Positive
- Reciprocal Translocation Negative
- Micronucleus
(446759) Completed
- Mice: B6C3F1
- Male Positive
- Micronucleus
(A65776) Completed
- Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
- Mice: B6C3F1
- Male Negative
- Female Negative
- Salmonella
(838866) Completed
- Citation: Canter, D.A., Zeiger, E., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Comparative mutagenicity of aliphatic epoxides in Salmonella Mutation Res. Vol. 172 (1986) 105-138
- Positive
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