Testing Information

Testing Status of Agents at NTP

Stannous chloride

Print this pageFriendly URL

http://ntp.niehs.nih.gov/go/TS-10747-F

CASRN: 7772-99-8

Formula: SN CL2

Synonyms/Common Names:

  • TIN CHLORIDE (9CI)

Known Uses:

REDUCING AGENT, IN MANUF. DYES, IN GLASS & PLASTICS MANUF, AS MORDANT IN DYES, IN MANUF. OF TIN CHEMICALS, COLOR PIGMENTS, PHARMACEUTICALS, PAPER, LUBRICATING OIL, TANNING AGENT, REAGENT, CATALYST (MERCK 1989).

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C02722) Completed 
    • NTIS No. PB82-242553  (Peer Review 06/23/1981)
      Citation: Carcinogenesis Bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N Rats and B6C3F1/N Mice (Feed Study)
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C02722) Completed 
    • NTIS No. PB82-242553  (Peer Review 06/23/1981)
      Citation: Carcinogenesis Bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N Rats and B6C3F1/N Mice (Feed Study)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0,500,7500, M: 0,1900,30000 PPM/10 PER GROUP

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C02722) Report Complete 
    • TR-231 (NTIS No. PB82-242553)  (Peer Review 06/23/1981)
      Carcinogenesis Bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N Rats and B6C3F1/N Mice (Feed Study)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Equivocal 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 
    • Dose: 0,1000,2000 PPM/50 PER GROUP

Genetic Toxicology

  • Chromosome Aberrations  (685652) Completed 
    • Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
    • Mice
    • Chromosome Aberation  Positive 
  • In Vitro Cytogenetics (CA/SCE)  (421347) Completed 
    • Citation: Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
    • Chromosome Aberation Positive 
    • Sister Chromatid Exchange Positive 
  • Drosophila  (362954) Completed 
    • Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • Mouse Lymphoma  (671517) Completed 
    • Citation: Myhr, B. and Caspary, W. Chemical mutagenesis at the TK locus in L5178Y mouse lymphoma cells. I. Results for 31 coded compounds in the National Toxicology Program. Environ. Molec. Mutagen. Vol. 18 (1991) 51-83
    •  Negative 
  • Micronucleus  (225751) Completed 
    • Citation: Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (741984) Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
  • Sister Chromatid Exchanges  (685652) Completed 
    • Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
    • Mice
    • Sister Chromatid  Positive 

Back to top

Web page last updated on January 22, 2009