Testing Status of Agents at NTP
4-Chloro-o-toluidine hydrochloride
CASRN: 3165-93-3
Formula: C7 H8 CL N.CL H
Synonyms/Common Names:
- RED BASE IRGA IX
Known Uses:
DYE INTERMEDIATE
Short-Term Toxicity
- 13-WEEK (Dosed-Feed)
(C02368) Completed
- NTIS No. PB295864
(Peer Review 12/13/1978)
Citation: Bioassay of 4-Chloro-o-toluidine Hydrochloride for Possible Carcinogenicity (CAS No. 3165-93-3) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0,6200,50000, M: 0,15000,20000 PPM/5 PER GROUP
- NTIS No. PB295864
(Peer Review 12/13/1978)
Long-Term Carcinogenicity
- 2-YEAR (Dosed-Feed)
(C02368) Report Complete
- TR-165 (NTIS No. PB295864)
(Peer Review 12/13/1978)
Bioassay of 4-Chloro-o-toluidine Hydrochloride for Possible Carcinogenicity (CAS No. 3165-93-3) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Positive
- Female Mice Positive
- Dose: R&FM: 0,1250,5000, MM: 0,3750,15000 PPM/50 PER GROUP
- TR-165 (NTIS No. PB295864)
(Peer Review 12/13/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(333979) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Weakly Positive
- Sister Chromatid Exchange Positive
- Mouse Lymphoma
(151592) Completed
- Positive
- Salmonella
(402517) Completed
- Inconclusive
- Salmonella
(721054) Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative
Web page last updated on January 22, 2009